I am not aware of any specific diet for Alport. Would recommend a general healthy diet

I tell my patients that it's not possible to reverse, but one can slow the progression of CKD by:

1. Controlling blood pressure ideally to < 130/80, 2. Lowering urinary protein (controlling BP with RAS blockers also helps with this). 3. Avoid medications that are toxic to the kidneys and 4. Be healthy (exercise/ diet) whatever is good for the blood vessels will be good for the kidney.

Thanks!

Thanks!

Thanks! For equations I would start with acid base and free water deficit. Check out this article for acid base. bcnephro.com/understanding-acid-base-disorders/

@BCNephro also how to calculate filtration fractions

I haven't heard of this. I do believe that sugars can contribute to inflammation though

It depends, things to ask your doctor are is the creatinine stable, is there proteinuria or an abnormal urinalysis, is there an abnormal renal ultrasound or is the blood pressure elevated

Thanks

Thanks

Things to consider and ask your doctor are if the creatinine and eGFR are stable and if there are other abnormalities on urinalysis, urine albumin or ultrasound

@ thank you. The eGFR has been at 64 as the best and 57 as the worst in the last two years. This is with 6 different examinations. There is no abnormalities in the imaging. Creatinine levels range 1.1 to 1.2.

You're welcome

Yes exxxaacctly! Mine went from egfr 46 to 62 in 1 month. All I did was quit sugar and carbs and drink more water. I didn't even realize how addicted I was to sugar and coffee. I think next time my egfr will be even higher and I didn't cut down on protein. Truthfully i increased protein by moving to a keto diet.

There are a number of reasons the eGFR could change/ improve like how hydrated someone is or medications. But, congratulations on working on your diet.

Congratulations on focusing on your diet and hydration

@@BCNephro Yes I think those 2 are the key. That was quite a scare for me because the doctor said after 3 months I would be diagnosed with stage 3 kidney disease. I had no idea what I was doing wrong at the time, or that there was a problem.

Thanks

Now what about your status

Thanks for the feedback. Let me know if you find this weeks video better. kzbin.info/www/bejne/h3y0koajfKynerMsi=go6704rquWbzL4_5

The calcium oxalate crystals form in the kidney tissue itself causing damage to the cells. Kidney stones form in the urinary collecting system.

@@BCNephro Thank you for the reply!

I've never checked a calcitonin level. This blood test is used for the evaluation for medullary thyroid carcinoma, not for the evaluation of hypercalcemia.

@@BCNephro Do you always see D 1,25 low in subclinical hypercalcemia where blood calcium isn't yet out of range? I've been talking to a few people that have falling eGFR and low PTH but claim to have normal D levels.

A low 1,25 vitamin D level would be expected in CKD with secondary hyperparathyroidism, with the elevated PTH maintaining the calcium in the normal range. However I don't typically check 1,25 vitamin D in this situation. An elevated 1,25 vitamin D can be a cause of hypercalcemia in granulomatous diseases like sarcoidosis or lymphoma. This would be a part of my evaluation in a patient with hypercalcemia and a suppressed PTH.

Check out this video and article. kzbin.info/www/bejne/gXLOiWqtr7GgqLssi=DGprWmDFd-fdNELd bcnephro.com/the-solitary-kidney-living-with-one-kidney/

Your welcome!

Your welcome!

Yes, thanks for the suggestion, I will work on this topic

@@BCNephro thank you

Alport syndrome video will be out tomorrow

@@BCNephro thank you very much

Received for lab result showing low anion. Thank you for video. Struggling on what direction I should consider to go with the result.

Thanks! Good to hear from you. Good luck in your fellowship!

That's great. How do you feel with your diet? What foods do you get protein from?

@@BCNephro A lot of tofu, chickpeas, and kidney & black beans. I do feel tired often, but also have insomnia I believe due to menopause. Stage 3A with 1+ protein.

Yes guidelines recommend it for this indication. Although I typical reserve it for patients with overt albuminuria already on a renin angiotensin system blocker. The link below has current recommendations regarding SGLT inhibitors in chapter 3.7 kdigo.org/wp-content/uploads/2024/03/KDIGO-2024-CKD-Guideline.pdf