Пікірлер
@anwarahmed7123
@anwarahmed7123 2 күн бұрын
Can we use Ivabrad to control HR , along with Dobutamine
@ranjithkumar-rm8zw
@ranjithkumar-rm8zw 4 күн бұрын
Gudmrng @tapesh sir what is the reason for thrombocytopenia in trauma patients, as thrombocytopenia becomes contraindication for epidural in many patient sir?
@youngindiaintensivist7709
@youngindiaintensivist7709 3 күн бұрын
Bcz of sirs/trauma induced coagulopathy
@ranjithkumar-rm8zw
@ranjithkumar-rm8zw 3 күн бұрын
@youngindiaintensivist7709 how long tranexemic acid is used I mean duration and frequency of tranexa in trauma sir???
@youngindiaintensivist7709
@youngindiaintensivist7709 3 күн бұрын
@ranjith,,,,Given 1 gm stat over 10 min and then 1gm over 8h as early as possible ,further doses can be given if TEG shows hyperfibrinolysis as Txa is antifibrinolytic -,usually not given
@ranjithkumar-rm8zw
@ranjithkumar-rm8zw 3 күн бұрын
@@youngindiaintensivist7709 and tranexa is it contraindicated in ihd previous stroke , dvt patients sir?
@youngindiaintensivist7709
@youngindiaintensivist7709 3 күн бұрын
@ranjithkumar-rm8zw if pt is ongoing thrombosis at some site then u would like to not give it.These are relative c/i .Absolute ci is urethral bleed as it can cause clot formation and urinary obtn
@shijinas8349
@shijinas8349 6 күн бұрын
Excellent talk
@puneetgoyal9858
@puneetgoyal9858 9 күн бұрын
Thanks for such a great presentation
@EDCRITICALCARE
@EDCRITICALCARE 10 күн бұрын
Content are good , quality of video / editing has to be improved
@tusharchopawar8255
@tusharchopawar8255 11 күн бұрын
Thank you so much Tapesh sir for so informative discussion
@Haywire91
@Haywire91 11 күн бұрын
Can we use the same strategy of treating severe hypokalemia (K <2) with mannitol and K in normal ICU patients in emergency situations to build up potassium (when we dont have a central line and are limited in the amount of K we can use through peripheral iv)?
@youngindiaintensivist7709
@youngindiaintensivist7709 10 күн бұрын
@Haywire91 This wont work, in hppk there is shift of k from ecf to icf so mannitol draws out k with water(drag effect) thus restoring it, along with k supplement . If u give kcl in mannitol in usual hypok where icf is also having low k you may increase ecf k but icf k wl decrease and you dont want that
@Haywire91
@Haywire91 8 күн бұрын
@@youngindiaintensivist7709 Got it sir. Thanks
@drdanielfreire
@drdanielfreire 12 күн бұрын
EXCELLENT
@ipathak7
@ipathak7 14 күн бұрын
Sir then which oral antibiotic should be given ico uncomplicated uti? Cotri?
@youngindiaintensivist7709
@youngindiaintensivist7709 14 күн бұрын
ipathak Fosfo satchets every 3 days for 2 doses ,cotri,levo are good
@ipathak7
@ipathak7 13 күн бұрын
@ but in the video only you said fq resistant is so high that its almost useless?
@youngindiaintensivist7709
@youngindiaintensivist7709 13 күн бұрын
@ipathak7 uncomplicated UTI is a term we use for non ICU pt generally. In ICU pt there would be resistance
@ipathak7
@ipathak7 13 күн бұрын
@@youngindiaintensivist7709 But in other comment you said that since mdr is rampant now in India, even community infections are very commonly coming out as mdr?
@youngindiaintensivist7709
@youngindiaintensivist7709 13 күн бұрын
@@ipathak7 it depends upon what your antibiogram of opd /ward pts is -- community resistance is variable. PL UNDERSTAND ONE HAS TO KNOW THE C/S PATTERNS OF PTS COMING TO YOUR ICU AND THOSE TO OPD , THAT DETERMINES YOUR ANTIBIOTIC USEAGE , THERE IS INCREASING RESISTANCE BUT IN CERTAI AREAS THEY ARESTILL EFFECTIVE ---THIS IS PRINCIPLE OF ANTIBIOTIC USE
@zahidabdulmajeed1482
@zahidabdulmajeed1482 14 күн бұрын
Sir, I have a few queries. 1. Static vs. Cidal Antibiotics: What is your perspective on the relevance of bacteriostatic versus bactericidal antibiotics in clinical practice? Is this distinction more of a microbiological concept, or does it hold significant clinical implications backed by any good quality data ? Mandel describes it in myths around ID .. also clinically never ever any cidal has fared better than static .. levo vs azee , vanco vs linid.. no data 2. Role of Double Coverage: In patients not on polymyxins, where we typically combine agents like meropenem or other carbapenems, what is the role of double coverage? When is it advisable to use this strategy or even back by good data ? 3. Empirical Use of Aminoglycosides: Is it appropriate to use aminoglycosides empirically without culture sensitivity? I am particularly concerned about fluoroquinolones, as Dr. Pratik mentioned, along with linezolid and amikacin-due to their anti-tubercular activity and the potential for causing false-negative results in suspected TB cases. That being potentially relevant in our settings 4. Clinical Usage of Aminoglycosides: During my DM residency at AIIMS, we rarely used aminoglycosides except for specific indications, and there was a general preference for alternative agents. However, since I started practicing as a consultant in Punjab, aminoglycosides are frequently used empirically, often without an antibiogram or known sensitivity patterns, which I have found challenging to locate. 5. Indications Where Aminoglycosides are Irreplaceable: Given the toxicity profile, are there any clinical scenarios where aminoglycosides are irreplaceable, or are there always alternative options? Thank you, Sir.
@youngindiaintensivist7709
@youngindiaintensivist7709 14 күн бұрын
1 static inhibit bacteria and immune system kills it Cidal kill the bacteria 3 conditions-immunosuppeession,neutropenia,IE 2 two abs as empirical coverage for sepsis to broaden cover that at least one wl work,also wherever cover with one anmb us not enough -pneumonia where atypical also needs an,gi where anaerobic also,enterococcal ie 3,amg - are good cheap drugs which still gives sensitivity However therapeutic window is narrow ,serum levels may not be ok,and tdm is needed which is not done in most icus in India,one can use as dual ab tharpy in initial abs for sepsis. Using alone in UTI ok as very hi conc in urine - but not alone in uti with shock/mods Other problem is ototoxicity--how wl u monitor if pts sensorium altered If these factors are taken care of one can use Aki is reversible and does not occur before 5 days, if we can use colistin in aki why not AMG 4.Specific indications are entetococcal endocarditis TB Brucella Tularemia Plague CF-tobramycin is good for pseudomonas
@zahidabdulmajeed1482
@zahidabdulmajeed1482 14 күн бұрын
@ thanks you very much sir .. I meant sepsis in hospitalised patients who aren’t in shock .. yes for curbing heterorrsistence in Acinetobacter we may add carbapenem plus polymyxins
@youngindiaintensivist7709
@youngindiaintensivist7709 14 күн бұрын
Carbepenams don't work for acireno any more Coli,tige plus mino is most potent U should go thru some lectures ,u wl find many answers What I hv written is covered in details in most of lectures
@zahidabdulmajeed1482
@zahidabdulmajeed1482 14 күн бұрын
@ I have started watching ID part sir .. I meant that double cover beyond as empirical therapy in a crashing situation like septic shock if backed by evidence .. minocycline is a good option one and effective even in presence of heteroresistance .. Static vs cidal is based on MBC/ MIC ratio more than 4 or Less than 4 ….. more an in vitro based microbiology concept … static also kills bacteria at conc. Above 4 times MIC … now how much target site concentration We have for some apparently labelled static drug will decide if it will be cidal … but sir … on clinical data side .. there are multiple RCTs , systematic reviews showing no difference or superiority of cidal drugs Rather data shows no difference to better with static ones like vanco vs linid in CAP , azee decreasing pnuemolysin causing immune modulation to far better than level .. Only place where imi fared better than tege was suboptimal Doses of tege wre used … so data anywhere doesn’t show that cidal should be prefered .
@zahidabdulmajeed1482
@zahidabdulmajeed1482 14 күн бұрын
Sir what is your opinion about 1. Cidal vs static 2. Double coverage unless we aren’t on polymyxins . 3. Do we have any empirical role of aminoglycosides.. at AIIMS in my residency we wouldn’t use amino glycosides atleast empirically … but here in Punjab it is used right and left … I don’t have data and antibiogram here … what u say sir about .. 4. What are their irreplaceable indications .
@caroverine2063
@caroverine2063 16 күн бұрын
Thanks.
@zahidabdulmajeed1482
@zahidabdulmajeed1482 18 күн бұрын
it is surprising , that despite high vasopressor scores just 35 percent on MV before ECMO..that too in those who had cardiac arrest , hypoxemia or low sensorium then only they would intubate them ... can I say they were optimised? .IF WE SEE THEIR MEAN PH , LACTATE and vasopressor score ....It is surprising to see just 1/3 patients only intubated...at such altered metabolic and hemodynamic parameters .. it is hard to say what outcomes would have been if they were optimised on mechanical ventilation prior to ECMO. also least duration of ECMO IS 10 hours ..maybe patient expired ... also sir is it like the variant with cold extremities unlike typical septic warm shock is only candidate for ECMO ... as it is mixed type of shock .. should there be lesser component of vasoplegia as like physiologically suitable for VA ECMO should they use some threshold SVR like they use threshold EF Also a review mentions NAC is only evidence based mortality reducing drug … Wonderful presentation and content sir
@youngindiaintensivist7709
@youngindiaintensivist7709 16 күн бұрын
Your point is well taken AS for CS cardiac index less than 1.8 to 2.2 L/min/m2, systolic blood pressure less than 90 mm Hg, pulmonary capillary wedge pressure (PCWP) greater than 20 mm Hg, and evidence of poor tissue perfusion, reflected by oliguria, rising creatinine and liver transaminases, mental status changes, or cool extremities, despite the use of OMM, constitute general guidelines for initiation of MCS.10 Patient history and overall clinical setting also need to be considered in the decision. SVR changes are secondary and wont help as you are already looking at these parameters al phos is characterized by low svr due to primary effect on capillaries despite being a CS which is supposed to hv increased SVR , alsi there is hypovolemia due to leakage . THUS HEMODYNAMICS are very complex But survival is possible now with crrt and/ecmo, if affordable
@zahidabdulmajeed1482
@zahidabdulmajeed1482 16 күн бұрын
@ sir true that is what is definition of cardiogenic shock as per shock trail.. I agree sir But my observation for learning was sir .. 1. Why wre only 35 percent intubated at such high dose of pressors and so high lactate . 2. As low SVR is reason maybe why ECMO isn’t working in septic shock … if this is a mixed shock … should we look for some SVR threshold so that it becomes more favourable in terms of outcomes on ECMO I know it is not something that alone defines indication and eventually a big difference on ECMO due to any reason is related to the volume of the centre for ECMO in a year however we have to encourage its use for such indications . Also in case of septic shock lactate kinetics is like that it increases before changes in macrohaemodynamic parameters ..while is CS FOR EXAMPLE IN CS complcating MI .. it is the macrohemodynamic parameters that deteriorate before lactate rise … since this variant of CS is also associated with mitochondrial toxicity like septic shock so that influences lactate kinetics being like one of septic shock .
@youngindiaintensivist7709
@youngindiaintensivist7709 16 күн бұрын
@zahidabdulmajeed1482 .. I would intubate such patient on high vasopressors and severe acidosis, (they hv used CRRT in such pts and found reversal , its their experience that is all i can say ) As for using SVR In rx for CS it is like I said a secondary change to CO , which is the main determinant One has to look holistically at the pt , numbers are a rough guide Whether one uses IABP OR ECMO one has to use it early , often they are used too late I am sharing below the link to a very nice lecture taken on our channel, you may kindly go thru it kzbin.info/www/bejne/fKS3k2dsa994r5o
@Gharashayantan
@Gharashayantan 22 күн бұрын
Very nice presesntation
@rishanabhpal4321
@rishanabhpal4321 25 күн бұрын
Many thanks sir
@doctordhruv2595
@doctordhruv2595 25 күн бұрын
I can't get my eyes off That Tie
@din2505
@din2505 20 күн бұрын
And the background light
@manujack4013
@manujack4013 26 күн бұрын
Thanks
@youngindiaintensivist7709
@youngindiaintensivist7709 25 күн бұрын
@manu....thank you for your contribution , it will help us in our daily expenses and improve content. if u need any academic help pl let me know ❤🧡💙💯💯💰🙏
@Avijit_Prusty
@Avijit_Prusty 26 күн бұрын
Thank you sir for making such Content
@Avijit_Prusty
@Avijit_Prusty 26 күн бұрын
Thanks
@youngindiaintensivist7709
@youngindiaintensivist7709 25 күн бұрын
@chimpu ..thank you for your contribution , it will help us in our daily expenses and improve content. if u need any academic help pl let me know ❤🧡💙💯💰🙏
@moinlala8078
@moinlala8078 26 күн бұрын
Any lecture on ckd??
@youngindiaintensivist7709
@youngindiaintensivist7709 26 күн бұрын
NO specific on ckd as our channel is more of icu - intensivist ,,, however u can see our nephrology playlist if anything is of ur interest kzbin.info/www/bejne/Y6vJipeklNR8oqcsi=X8_DsfuAMhV3liTl
@manujack4013
@manujack4013 26 күн бұрын
Hi sir....management of severe metabolic acidosis...euglycemic dka....indications for intubating them and ventilatory management in severe met acidosis...if possible a video on that sir🙏
@youngindiaintensivist7709
@youngindiaintensivist7709 26 күн бұрын
@manu ..pl see reply in post , u hv asked a good q so hv out it there for all to see
@manujack4013
@manujack4013 26 күн бұрын
Ok sir thankyousomuch sir
@ranjithkumar-rm8zw
@ranjithkumar-rm8zw Ай бұрын
Thanks for discussing the topic and case I have asked sir
@ranjithkumar-rm8zw
@ranjithkumar-rm8zw Ай бұрын
Thankyou for crp and procal sir
@rajputrajan7048
@rajputrajan7048 Ай бұрын
Sir , Colistin is prodrug which activates in renal parenchyma so preferred choice of urosepsis and poly B is active molecule preferred for bacteremia In CNS infection due to carbapenem resistant GNB , intrathecal colistin preferred over poly B? And what is funda of nebulized colistin if it is a prodrug It's need to be activated in kidney then why don't we use poly B in place of colistin for local effect?
@youngindiaintensivist7709
@youngindiaintensivist7709 29 күн бұрын
@Rajput CMS conversion to colistin occurs at other sites also ,not only bloodstream Thus it generates colistin in csf and resp tract as well The other advantages of colistin over poly b are there is more data and experience with its use..poly by was used much after colistin, then poly b is more irritable to meninges and airways and third colistin penetration into meninges is more After all that said, can use poly b as well ,there are no proper data comparing the two in such situations ,to the best of my knowledge
@sankalpabhattacharya8015
@sankalpabhattacharya8015 Ай бұрын
Excellent lecture the entire series of lectures in this channel are a boon to all of us
@anandtiwari52
@anandtiwari52 Ай бұрын
Elaborate n excellent, Ma'm.
@shrutipareek8178
@shrutipareek8178 Ай бұрын
Thanks
@youngindiaintensivist7709
@youngindiaintensivist7709 Ай бұрын
@shruti ,, thank you for your contribution , it will help us in our daily expenses and improve content. if u need any academic help pl let me know ❤🧡💙💯💰🙏
@pallavibojja5142
@pallavibojja5142 Ай бұрын
1cycle means 1set of 30:2 , in 2min we should perform 5 cycle ( 5 turns/ sets of 30:2) right sir...if person received 10 min CPR means he received 25 cycles... hope my understanding is right?
@youngindiaintensivist7709
@youngindiaintensivist7709 Ай бұрын
@pallavi ..5 cycles of 30 compressions and 2 breaths typically take around 2 minutes when performed continuously at the recommended rate. of 100 compressions/min .This timing guideline helps ensure that rescuers switch after every 2 minutes to avoid fatigue, keeping the quality of compressions U r right in calculations
@pallavibojja5142
@pallavibojja5142 Ай бұрын
Thank you sir
@eusobmollah1679
@eusobmollah1679 Ай бұрын
Sir plz give a short notes on Levocetrizin & Levosalbutamol dose in paediatric
@youngindiaintensivist7709
@youngindiaintensivist7709 Ай бұрын
@eusobmollah1679 , , i am sorry but i am not a pediatrician so wl not be able to help with your querry
@AhmadRaza-ye9qg
@AhmadRaza-ye9qg Ай бұрын
Should aminoglycosides be given in divided doses in pts of cystic fibrosis?
@youngindiaintensivist7709
@youngindiaintensivist7709 Ай бұрын
@AhmadRaza-ye9qg , there is no indication as per literature to give in divided doses in CF though there is controversy , in fact nebulized AMG are used in CF along with systemic appropriate ab,. Toxicity of AMG is less in CF for unknown reasons Divided doses of genta are used in IE and when used in synergy for gram pos organisms
@dr.tintithansari673
@dr.tintithansari673 Ай бұрын
👍🏻👍🏻