THANK you for this !!! my teacher rushed pasted this and i was so confused for the rest of the lecture
@thebeatles9Ай бұрын
the synthetase identifies the AA using chemical discrimination and size filtering. it finds the tRNA via identity elements (anticodon loop, signal etc)
@thebeatles9Ай бұрын
Mg2+ is required during the very first step of binding ATP
@thebeatles9Ай бұрын
Class 1 aaRS will bind to the 2' tRNA hydroxyl, class 2 will bind to the 3'
@thebeatles9Ай бұрын
The synthetase is a 2 step rxn. it binds the ATP + AA and then second step is bound to the tRNA. Proofreading is done at a second site, but this whole thing is done without it ever being detached from the synthetase
@MariaFernanda-oz6ufАй бұрын
thank you, this was fantastic and helped me so much, i appreciate your work! <3
@isabellacorrea8007Ай бұрын
Thank you! 💙
@hazel56262 ай бұрын
If I succeed and pass dental school, I am going to donate money. You are the reason I understand biochemistry. You have a talent for teaching something so difficult in an easier manner. Thank you Moof!
@Productivenancy2 ай бұрын
9 years passed after you shared these videos but it still helps to student thanks aloo this channel is the only chanel that i can find videos properly thanks a lot
@kazukitimuzo15992 ай бұрын
Thanks, was really helpful since exam is ahead
@HawiMolallign2 ай бұрын
I have no word for you❤❤❤
@LushomoNatala2 ай бұрын
Wonderful explanation 👏🏿
@hazel56263 ай бұрын
I have been watching your videos for years (8 years). The way you explain and make it easy to understand is beyond my comprehension. Just like biochem you take one very improbable event and make it very probable by cutting it into small chunks of digestible materiale. Well done Moof, thank you so much. Much appreciation
@hazel56263 ай бұрын
MOOF YOU'RE THE BEST IM IN DENTAL SCHOOL AND YOU ARE SAVING MY LIFE
@adabesirbayraktarstudent62003 ай бұрын
STİLL RELEVANT THE BEST
@manassehagbeshie15743 ай бұрын
Really?
@saraburres3 ай бұрын
all of the puzzle pieces clicked together with this video
@JesusLightsYourPath3 ай бұрын
I typically dont learn well by just reading words. I'll have to find a more visual video.
@zakirzak14943 ай бұрын
❤
@zakirzak14943 ай бұрын
❤
@zakirzak14943 ай бұрын
❤
@zakirzak14943 ай бұрын
❤
@kallie90594 ай бұрын
Thank you for your videos. I had to learn biology for my hesi exam and thanks to you, i passed my exam. I owe you my grade in the biology and chem portion of the hesi.
@sunil868604 ай бұрын
Nice Just explain how and where H attach in adenine They are 5 but in structure , less
@pariasepahrad7164 ай бұрын
Thanks
@samngmusic5 ай бұрын
amazing explanation!! this was always a topic i kind of ignored as i could never understand it well. now i am revising for the upcoming schoolyear and refreshing my memory and realised that i have never sat down to cover this topic because it was always so frustrating. i am so glad i found this video. no more confusion for me! :)
@Private.anatomyo5 ай бұрын
bro if i get alot of money i will pay for you because surely you were a big resason that i could take these money one day , and all the patients will be greating to you as you make doctors understand the hell they memorise , thank you , thats what we say about to do something meaningfull
@naseemahmadahmad27946 ай бұрын
Best❤
@mahmoudofficial-e5w6 ай бұрын
bra wth i would spend years without your videos , thx alot, my worst dream is your youtube channel bieng hacked
@vinayKamera6 ай бұрын
10 days before finals i found super amazing cobtent
@orangecaprinun6 ай бұрын
2:50 I mean its your drawing but really it looks like each ball is a nucleosome and the 8 "histones" you marked as a nucleosomes are just a string of chromatosomes, since like i said each histone you drew looks like a nucleosome. histones don't start arranging in a linear manner, they bind to each other forming a spheric or disk complex called an octamer even before DNA is wrapped on them, when it does, the complex is called a nucleosome
@vitorabdala17 ай бұрын
Does uracil bond to deoxyribose?
@ranudansena15517 ай бұрын
Excellent 👌👌👌👍 superb performance
@Lina_009948 ай бұрын
You forgot about the idea of palindrome, the inverted repeats are like a palindrome. But great video
@hazel56268 ай бұрын
I am currently in dental school and thank you for making these videos. Prior to dentistry, my major was biology and you helped me then and you're helping me now. These videos make it crystal clear to understand and to revise. Thank you so so much.
@I_am_reverseflash8 ай бұрын
Very helpful much more clearer than I was thought. Thanks for actually showing how to plot it rather than just explaining the formula and go.
@saheedsheriff19938 ай бұрын
Thank you sir, great and helpful video sir ❤🎉
@KvotheArliden8 ай бұрын
Best video for amino acid metabolism I have come across, thank you sir for you great work ❤
@zainb58728 ай бұрын
Thank you!
@hesham-wu9ql8 ай бұрын
Best lectures of biochemistry available on internet. Hope u make a comeback and make videos again. 🎉
@halqthedarktemplar9 ай бұрын
On our textbook (The principles of biochemistry of Lehninger) it says that citrate synthase is stimulated by ADP, Isocitrase DH is stimulated by ADP and Ca2+ and alfa chdtoglutarate DH is stimulated by Ca2+
@Mateusz-ji9dn9 ай бұрын
Okay understandable, but can exons be set up in different sequence than they were in pre - mRNA? For example in pre-mRna we have the order like: 1234 exons, but in mRNA we are going to get 1423 exons?
@yichalalzewdieАй бұрын
No. The chance of getting different exon sequence is rare, unless they are subjected to mutation.
@mulugeta83269 ай бұрын
Thank you so much for your great presentation!
@anujsharma78539 ай бұрын
How beautiful it is 😍
@kawanganyirenda4529 ай бұрын
The Histidine since it's found the myoglobin being positively charged amino acid but why saying it's the T- State of Hemoglobin conformation being stabilized . Kindly make mention of the connection between these two globular proteins Sir .
@floriandepol42409 ай бұрын
Hi, I am posting this comment especially for undergrads watching this video as a support. In this video, the biochemical logic of glycolysis regulation is explained. To the extent of my knowledge, the content is correct. However, it is important to point out that nothing in the video actually demonstrates that the regulation is indeed "allosteric". Allostery is when an effector molecule binds at a site distinct and remote from the active site, triggering a change in activity/function. Without showing the structures of these enzymes - or any experiment showing that the the binding of the effector happens far away from the active site - it is impossible to tell whether the regulation is allosteric, competitive, etc, etc. What is explained in the video is the logic of the regulation pathway, independently of the inhibition/activation mechanisms :-)