hello, just finding your account. I have tried the same medications as you. Also have had the same experiences on each. I just gave up on trialing adhd meds becasue they make me so anxious. But im so lethargic and depressed now after quitting vyvanse. Lexapro has been great for me but now im suspecting they may have been making me fatigued all this time. I just bought caffeine pills to try and make up for this. I was thinking about switching to trintellix until i found your video. I was also considering giving wellbutrin one more time. I tried twice and both were bad times so idk anymore esp after hearing your story. I wish there was a adhd medication more like caffeine lol. Have you found anything new that works for you?

I might be wrong, but doesn't lower nM values mean stronger binding? So, wouldn't Ansofaxine actually bind to DAT more than SAT and NAT (and be more selective towards the dopamine receptor)?

Thanks for this, I’m considering the same switch for the same reasons

I started Paroxetine last week for recently developed panic disorder. My issues are new enough that my psychiatrist believes I can make a full recovery and be off the meds within a year, which is awesome to hear. But all the same, videos like yours make me a whole lot less nervous about being on these meds even if I have to be on them longer, or even for the time I am required to be on them. Thanks very much!

How are you darling?

SSRIs have too many serious side effects and are way over prescribed. The hypothesis that low serotonin is the cause of anxiety and depression has been debunked. These drugs affect serotonin levels in the brain and the side effects are as a result of there being too much serotonin. It takes several weeks before the receptors begin to down regulate and over time disappear as a response to too much serotonin being present in the synapse. These drugs don’t cure anything and have too many downstream effects. SSRIs should only be reserved for those who are in a really bad state and therapy alone isn’t working and on a short term basis. We as a society need to question why is 1 in 4 people in the US on an antidepressant Only 1-2% of your body’s serotonin is actually in your brain and 90% is in your gut.

Thanks for your excellent video . The side effects that I've had from SSRIs are an almost uncontrollable desire to drink alcohol . After I contracted Covid in March 2024 I switched from Paroxetine , which gave me urges to drink or maybe I have little willpower , to Mirtazapine . With Mirtazapine I had maybe 4 drinks in 6 months with no cravings , which is quite a change , but it didn't help my depression - anxiety . So my doctor suggested Fluvoxamine 100 mg . Ever since I've had very strong urges to drink again and have done so a few times . Some people have sexual side effects but there is also a lesser portion of people who have to deal with the urge to drink . For me SSRIs are a slippery slope even though they are always the first option .

I think this stuff is messing up my life like every other thing that I’ve tried in life. The question is do I want to mess my life up exponentially like a punk rebel anti-conformist or more liner like a square conformist yes-man?

i was on trintellix for 5 months and had to stop it cause of vomiting but it had cured most of my problems though

What are you talking now ??

should it completely dissolve in water? i just tried this and I just see the medicine swirling around and sinking to the bottom. I was shaking it for a while.

Doesn’t work for me at all

Im cross tapering from paxil 30 mg with zoloft 25 mg been a week and im at 10 mg paxil and the zoloft but fml it’s kicking my ass i only did 2 days on 20 mg per doctors orders lmao but he did say to stay at 10 for 2 weeks and depending how i feel stop or go down to 5 and continue the zoloft. This is rough man 😞

If it doesnt work well, you could ad 1mg brexpiprazole, or 1.5 mg Cariprazine

Seroquel is the best for me but its bad for you

I’m Chinese and I’ve use toludesvenlafaxine for a month. For me it’s pretty good! Especially in improving the cognitive abilities decreasing caused by depression (The increase in dopamine levels in the hypothalamus and prefrontal cortex is higher than that in desvenlafaxine）. I kept using Fluvoxamine and Bupropion for 2 years in the past and I have become drowsy（Fvxm） and my memory has declined（Bpp）. Luckily Toludesvenlafaxine doesn't cause these problems and as SNDRI, it’s better than them(SSRIS+NDRI) in all aspects. But now my libido has decreased(honestly I think it’s good cuz it can calm me down)and ejaculation is delayed. But some people felt useless because of the individual difference. If you are troubled by the cognitive ability decreasing caused by severe/extended depression and refuse stimulants this may be a very good choice 👍

Did it end up helping with your anxiety

Here's candid. Antipsychotics [or more appropriately, 'neuroleptics'] are very powerful, dangerous drugs that can and do cause permanent brain changes, brain loss and severe disabling and chronic mental illnesses including schitzophrenia as well as shortening lifespan; not to mention movement/metabolic disorders and worse. You are gambling with your future for anxiety/insomnia relief? To whose gain? I bitterly regret ever taking these drugs and I am far from alone. WE are the long term studies. Take care. ps. 'antidepressants' are also dangerous. pps. exercise, diet, friendship, conversation, hobbies... just some non-drug solutions. You only get one body and brain. They're more valuable than doctors' wallets.

You forgot moclobemide/Aurorix

Buspirone could be a good adjunct . Mirtazepine and mianserine are common used as "boosters" . Good luck!

Pregabiline is really good for sleep

Thanks from India.i am 57 had acute anxiety since I was 25 .I find your symptoms similar to mine.i am on lexapro 20 and ambien 12.5 since nothing will make me fall asleep. I wish everything works well for you.

I took 20mg a day. Didn't do a thing for me.

Yay pill doctor 😂😂

What are taking now

Lexapro affects libido, sex drive not good

Couldn’t you just take half a tablet of each. ,get the best of both worlds brother , king of the jungle

The main thing I noticed about Trintellix is that it has a big set of balls

I tried ambien, rivotril several years and I came off thanks to a addiction center. Now I take trazodone for sleep and it's good! Not addicting, wake up good, sleep 8-9 hours. It's the extended release. I've tried antipsicotics but I dislike them so much

I took fluvoxamine but I was sleepy all the day and I could't focus on things

Bupropion (Wellbutrin) is the only antidepressant that really worked for me... Lifechanging. Feels natural, few side effects, introusive thoughts gone, anxiety almost gone, self esteem improved

How's the sexual side effects on this new medication?

I have had this for 3 years even tho im bipolar type 2 and a half (bd 2, 1/2).. not good trying to quit now

Did it help you with Insomnia ?

Have you had genetic testing for determine what meds might be more beneficial and which are likely to be poorly processed? I did genesight and it’s been validating. I had an ok time on Prozac, it didn’t ramp up anxiety or give me nausea, which is good because I had really bad anxiety at the time. It did interfere with libido and ability to climax. I didn’t notice it doing anything good for me, but in retrospect I can see from the way I interacted on social media that it had a positive effect, I was more patient with people when they were irritating. I was less reactive. Unfortunately I was asked to go up to a higher dose (doctor didn’t think I was at a beneficial dose) and as soon as I did that I started having tremors so badly I couldn’t work or even feed myself soup, so shaky! It’s been ten years since I’ve been on any meds and am about to start over (to cope with pandemic/climate/recession stuff, but also manage adhd traits like executive dysfunction and fatigue) which is how I found this video. My new doctor wants me to try Luvox and then add in Adderal. He is basing this on the genesight info and his years of experience with neurodivergent people, but I’m scared to take anything that might give me anxiety or weird side effects like that. That being said, my psych nurse who is the one actually helping me with the med journey thinks I should start back on Prozac again since it’s “the devil we know” and see if I have a better time of it since things may have changed for me. We see it as a jumping off point to to open the door to trialing other meds if it doesn’t fit just right. I’m at a crossroads, and was hoping to understand the difference between the two as she said one is much like another and it didn’t really matter. My doctor disagrees and said that’s why we did the gene test and why I came to him as he has the most experience. He is probably right. 😂

I get zero sleep, so id take some next day tiredness. Im starting at 25MG.

Antidepressants cause PSSD

How’s it going with Luvox? Cant wait for your update

Thanks You

DANGERS OF BRIDGING Interaction between the two drugs creates risk of developing serotonin syndrome. Switching to another drug does not necessarily stop antidepressant withdrawal. The person may switch to new drug and still develop Protracted Acute Withdrawal Syndrome from rapid discontinuation of the old drug. A doctor may misdiagnose withdrawal as a mental health disorder and apply more drugs. The new drug(s) also cause(s) dependency and will need to be slow tapered. Repeatedly going on and off psych drugs can "kindle" or sensitize the nervous system making future discontinuation attempts more challenging. The best way to minimize withdrawal symptoms and reduce the risk of developing protracted withdrawal is through a slow taper with decreases no greater than 5% of the previous dose holding at least 14 days between drops. The general rule of thumb is to add up the time you have taken any antidepressant, and divide that time in half to know how long you should take to wean off while working to rebuild your ability to metabolize serotonin. If you've been on longer than 5 years, a 1.3 year taper for every 5 years on. As a conservative harm reduction approach, tapering no more than 2% to a 5% reduction every 2-4 weeks. EACH PERSON IS DIFFERENT AND SOME CAN GO FASTER THAN OTHERS. Most doctor's are clueless about tapering off these drugs. 1. If a doctor tells you that antidepressants are not addictive or do not have a host of adverse effects, that is incorrect. 2. If a doctor tells you to skip days or go every other day, that is wrong. 3 If a doctor tells you to simply stop taking any antidepressant that is not only wrong but dangerous. With the exception of a diagnosis of Serotonin Syndrome you must cease with taking the antidepressant/offending drug. 4. If a doctor tells you withdrawal only lasts two weeks and isn't that bad, s/he is misinformed.

Thank you for sharing that mate, I hope you are doing well now

I will try this, the crash is horrible, I dread going back to it after being off meds for a few days.

I'm still waiting for the magic to begin, to be honest. I was on 5mg for a month and have increased to 10mg a week ago. What I have noticed is that I am able to get out of bed as soon as a wake up, and I can get on with the day, but I still feel quite sad. Not as depressed but just flat...feel like crying a lot of the time. No anxiety but then anxiety wasn't the issue with me... it was MDD. No side effects at all. I just wonder if it is going to work. None of the SSRIs helped me and I had awful side effects.

Same here.. Trying first time brintellix... Because all the other antidepressants cause serious problems in my sex life..

Yep thanks for this, I tried what I read the other day and it was mind blowing to see her writhing with pleasure and ready for anything. It started when I learned to last at least 30 minutes go’ogling the latest in Greyzar Drinbo's PE Solution and now she just can't have enough

Man I can relate on the Lexapro. It was a game changer until it gave me delayed ejaculation then it took my orgasam then my erection and sex drive. It was progressive. Like you I've tried about every other antidepressant. I just started trin.

Im 2 weeks into it and feeling much better than i did on Lexapro.

Have you tried Mirtazapine for sleep? far less side effects than Seroq & Trazo and is used in conjunction with SSRis quite frequently.

A dziala wogole na zaborzenia lekowe w dawce 5 mg?

What do you think about controlled MDMA therapy sessions? It seems very promising. I had taken it without therapy and still had relief from depression for a long time, kinda like a quick rest in your brain. Obviously it's not something you can take regularly but combining it with therapy like 2-3 times a year could benefit people who suffer from depression and PTSD.