Allen frances is the man!!

please have Jonathan Shedler on!!!!

Is clonidine safe and effective for a mild tic disorder that was worsened by Dextroamphetamine and bupropion? Those meds had to be stopped because of this. Adult patient

We need Allan Frances and Marvin Goldfried's youtube podcast videos to continue on!!!! what happened???

Because the illicit stimulant supply is contaminated with fentanyl

First! Shedlerians unite! Shedler the man!

This is embarrassing. He spends the first half criticizing psychotherapy AND psychotherapists without saying anything to indicate psychodynamic therapy has any efficacy whatsoever

Lollygagging about what evidence-based means = poor evidence of efficacy for psychodynamic psychotherapy.

Currently, there is no way to distinguish schizophrenia by blood test or MRI test in psychiatry. If you just tell yourself that you hear hollucination and check the checklist, the schizophrenia medicine is prescribed immediately. What I want to reveal here is if whether a normal person can live a normal life if he or she takes the schizophrenia medicine for without no reason just by misdiagnosis a long period of about 6 months and stops taking it. I currently speculate that if a normal person takes a schizophrenia medicine like abiXXXX(for example) for a long time, the schizophrenia medicine may occur the lose the ability to control dopamine in the brain, which can lead to schizophrenia. There is a fact in Korea, after the release of the Luracidone medicine that is known as it has no side effect of gaining weight , i could find the newpaper article that introduce the side effect of weight gain in current schizophrenia medicines. Similarly, when all prescriptions for schizophrenia are changing into cobenfy and then it is necessary for research of current schizo medicine to verify that there is no abnormality in the function of controlling dopamine when a normal person takes and stops taking it for a long time.

Go Lithium 😎

Buspirone plus melatonin ❤️ google it also removes sexual dysfunction

Appreciate the talk. A lot of good points. Maybe there is some hope.

thank you for the thorough explanation!

Thanks for the forecast! I need some advice: My OKX wallet holds some USDT, and I have the seed phrase. (alarm fetch churn bridge exercise tape speak race clerk couch crater letter). What's the best way to send them to Binance?

I couldn’t remember what I did from one day to the next on BuSpar in the 90s. I’ve never had any patients say anything good or bad about it, but it was a major problem for me.

Curious what's the effect size of gabapentin as well as pregabalin for GAD

A lot of what Dr. Healy seems to make sense. But if providers were to try to stick to treatments with more observable therapeutic effects, then does that mean he would be more willing to provide benzodiazepines over SSRIs for anxiety disorders?

Eminem isn't dead

Love this episode

wow, this should be a weekly thing, so interesting to listen to Edward Shorter, thanks!

I use this a lot in practice

This is a prime example of how non-prescription alternatives may help patients and is likely not as well known because it is not advertised by the pharmaceutical industry. I’m interested in learning how it benefits my patients.

If no psychiatric textbook has ever suggested that depression is due to a chemical imbalance in the brain, then why would the media say this?

to simplify, try using the Diagnostic Hierarchy (ADD is a 4th level diagnosis) and Diagnostic Validators (famiy history, course are most relevant) since symptoms alone can not differentiate BP from ADD. see Clinical Psychopharmacology Principals and Practice - 2019. Dr. Ghaemi recommends valproate or lithium 1st line for mood temperments not lamotrigine.

This medicine literally worked in less than 15 min and its a life saver. Nothing has worked for my depression but, this medicine has worked! It’s fast, no side effects. Its been about 2-3 months. I hope people don’t abuse this medicine and make it extremely hard for people who actually need it to be able to have access to it. Finally something that targets the right receptors and provides almost instant relief from the disease. I wonder if this is How everyone else feels that don’t have depression? Is this what normal feels like? 😅😊

Given Qsymia, even tho obesity is distinct from BED, seems obvious to try lisdex+topiramate.

Thank you for everything you do.

In anhedonia support groups MAOIs (more specifically Parnate) are anecdotally discussed as being the most effective treatment, however the sample size is small because very few members are able to get it prescribed.

for the exercise vs medication trial the rates of relapse after 10 months showed that exercise trained were 4x less likely to relapse, but those who actually still exercised at 10 months were only 50% as likely to relapse? how does this work out?

Links mentioned in the podcast: Study: Telemedicine for Mental Health in the United States: Making Progress, Still a Long Way to Go psychiatryonline.org/doi/10.1176/appi.ps.201900625 Study: A Potential Case of Acute Ketamine Withdrawal: Clinical Implications for the Treatment of Refractory Depression pubmed.ncbi.nlm.nih.gov/34270337/ NYT Article: Soaring Use of Ketamine Creates a Health Care 'Wild West' www.nytimes.com/2023/02/20/us/ketamine-telemedicine.html Study: Maintenance or Discontinuation of Antidepressants in Primary Care pubmed.ncbi.nlm.nih.gov/34587384/ Study: Initial Treatment Choices to Achieve Sustained Response in Major Depression: A Systematic Review and Network Meta-Analysis pubmed.ncbi.nlm.nih.gov/34505365/ Study: Adjunctive Lumateperone (ITI-007) in the Treatment of Bipolar Depression: Results from a Randomized Placebo-Controlled Clinical Trial pubmed.ncbi.nlm.nih.gov/36779257/

Hi, I would appreciate references to the studies you refer to at the end of the podcast. Thanks!

The Carlat Report provides great information, and I really appreciate it. However, after listening to these two, I feel like I need an antidepressant! It seems like they could share the same information without being so negative about everyone and the field in general. I definitely wouldn’t attend their motivational speaking conference. Haha.

Dear Nasir, I’ll start with a simple quote… “if empathy and invalidation were mixed together, your analogy would be like mixing water and vinegar. I’ll start my rebuttal With all due respect, Your logic may have merit, however, a bold statement (quoted below), is invalidating to patients and those who treat them. You have a responsibility for the impact of this statement, especially without empirical research,; its harmful or incredulous for a speaker on this topic.

As a newer psychiatric provider, these insights are extremely valuable and are helping to explain things I am seeing in my practice. I would like to learn more about Dr. Ghaemi's views on psychiatric diagnoses, particularly bipolar disorder. Could you recommend specific books or online resources for this? Some of the books I see have older publication dates, not necessarily a problem, but I want to make sure I am getting the most up to date information on such a controversial topic. Could The Carlat Report or Dr. Ghaemi make a recommendation for work by him or others that is a reflection of his current views? Thanks!

Starting the week with a Ghaemi interview? What a treat!

Do you do telehealth

Tyvm

That was a very informative video. Very well put together. Look, there not building it up like its some wonderdrug but creating an awareness around it as if it could be an improvement to your current medication

ΜΕΤΑΦΡΑΣΗ

Great presentation, Dr. Carlat. May I inquire.. You mentioned at the end of the podcast stimulant use which I assume includes ADHD Rx.. Just how much of a risk factor is it to utilize these prescribed stimulants during strenuous physical exercise for an otherwise healthy adult 25-40 years old? This seems concerning as the trend in pharmacology seems to tilt increasingly towards extended release formulations which would require prevent physically active people from being able to mitigate that risk while exercising. Thank you.

Awesome update, Chris! Really enjoyed your presentation on higher dosing yesterday 😊

Due to it not being a traditional SSRI or SNRI, 5-HTIA receptor is a unique antidepressant neurotransmitter. This means it may work for people who don’t depends to the other antidepressants. Shouldn’t you know this as a prescriberb

Thank you for this video! I see a fair share of patient whom seems to meet the diagnostic criteria for ADHD well, however some also use cannabis to varying degree, and right now my approach is that as long as I don't think the stimulant will worsen their substance use or other mental health symptom, I rather keep them on at least a low dose stimulant to address their complaint and also maintain therapeutic rapports, so that hopefully we can also later work gone and eventually reduce cannabis use thru other forms of treatment (CBT etc.)

adderall is meth.... Cmonbruh

weed is way better and safer than adderall.... Cmonbruh.......

I practice in a region where cannabis is very popular for recreational use. I always appreciate when there is new data regarding this substance and how it makes my job harder.

👋👋👋👋 excellent work

Amazing, per usual! Would mind sharing the link for those studies pls?

Always love the podcast, and this format is lovely! Please keep up the good work, I hope more trainees and practicing psychiatrists check you guys out. (and love the collab between Carlet and PsychoFarm!)

reducing/eliminating risk of drug-induced movement disorders can be viewed as game changing