Headaches was on the image called “Shining a light” - it was on the predominantly female side.

@@beckster6116 Thank you I didn't see it!

Hi, with respect, I think you maybe misunderstood where people are coming from for much of that. People are disappointed because this is a long overdue study that is a very large and extremely well planned study design, that is highly likely to yield very definitive answers around whether ME has a genetic link, BUT ALSO what areas of the genome might be involved - that could lead us to new areas of research or highlight existing areas that need to be prioritised with much better funding. That's a really big deal! It has the potential to change the entire nature of how ME is viewed globally, and enhance the argument for much greater funding whilst we're at it. There is MUCH to gain from this study. There may indeed be a negative outcome, with no genetic link found, but this is relatively unlikely since ME doesn't just run in families, it runs in family lines with some grandparent having ME, who has died long before their grandchild is born, and then their grandchild goes on to get ME also, this tells us it can't be environmental eg exposure to the same trigger or virus etc, because they're separate households, separated by many years, this strongly suggests a genetic link. So there is very good reason for us to have hope that a link will be found with this study. They almost certainly wouldn't havegot such a huge amount of funding for it had there not been a pretty good chance of a positive result here. And as I mentioned there is a lot else to be gained too from it. So I can understand why people will find this a tense wait wondering whether it will fulfill our hopes for it. The researchers too I would imagine. It's only natural. This isn't any old study, this is a particularly important one, it's very large for starters - which is unusual, I imagine you already know that, in ME research, larger studies have way more potential to find meaningful results that move things forward - especially true in a GWAS piece of research. I think it's absolutely appropriate for everyone to be very excited about this particular study, it really could change things substantially moving forward. The chance that it doesn't show a genetic link at this level of participation, is exactly what makes everyone nervous in the first place. It just makes it feel more high stakes. So I suppose that's why we are on tenterhooks until the results are here. The comments are almost all very respectful towards the researchers, most people do understand why science can take a while I think, although not everyone always has a great understanding of exactly what it takes, it's just a misunderstanding of how science is carried out though that's all.

Counting down the days to what? The project has not said and cannot say that they will find any definititve results. One outcome might well be that they find zero DNA correlation with ME. I think you misunderstand science trials, and science.

......to the findings, whatever they may be. I haven't misunderstood anything. I'm just disappointed. This is, after all, a platform for comments.

You maybe desparate for answers but all this study might well show is that there is zero correlation between ME and DNA. Anyone involved in this project to get resolution for their ME is in the wrong project and does not understand the science.

One perfectly reasonable result of the project would be to find that there is no DNA relation to ME at all. This would progress the understanding of ME. People should not be disappointed by finding no clear correlation or distinct patterns uncovered. There should be no pressure on the scientitists to find something that isn't there.

@@FireflyOnTheMoon I agree, but I'm a little unsure why the comment is aimed at me, I have never expected anything except the knowledge that will come from whatever the results of the study might be. No-one is putting any pressure on the outcome, least of all me, I mean it's science, it shows whatever shows, that's the nature of the beast....the attempt to establish truth, whatever that ends up being. The result will be an answer one way or another.