Thanks for a great technical video on Gd chelate. I have a few follow up questions. Which organic molecules can Gd bind to in its competition with Ca and is the competition from free Gd, Gd chelate, or both? Also, Gd can block voltage-gated calcium channels, which can prevent nerve impulses from transmitting and block enzymes that depend on calcium. Is the chemistry behind this understood in terms of free vs chelated, and if the interruption of these processes by Gd is long lasting? Lastly, did the brain biopsy study you mentioned identify species of Gd deposited in the brain (free/chelated)?
@superroofer61414 күн бұрын
Lost my smell and taste in march 24 still not right , currently i have constant smell of fat with chemical smell in my nose every thing smells the same ( HELP )
@BhanuPrakashsci4 күн бұрын
I’m following this channel after i watch MRI physics from 11yrs back. Keep going Sir. Great job
@johndutton36795 күн бұрын
Brilliant synopsis! I had focused ultrasound surgery done 3 years ago and it changed my life and in the time it takes for a long lunch!. My tremors were abolished 100 percent and have stayed that way. Check out my film Tremor Documentary 2022 and it will show you the entire operation. It's a freaking miracle!
@iot31366 күн бұрын
❤❤❤❤❤❤❤
@aleksandrac93357 күн бұрын
I lost smell yesterday 😢😢😢😢
@RanDom-Interloper7 күн бұрын
This video is 3 years old. So what happened to the further studies on Ivermectin???? Out of sight out of mind???? Where's the follow up???? Irresponsible. Typical, no profit? No research.
@pitendrajatil8 күн бұрын
ONE OF THE BEST VIDEOS ON THE TOPIC . THANKS.
@Colonel_Brock8 күн бұрын
I was honored to have a role in developing RFA for solid tumors at UC Davis.
@DoctorKlioze8 күн бұрын
That’s awesome!!
@marcosbravo879 күн бұрын
As and an MRI tech you explained it very well Dr
@ozfreak269 күн бұрын
Well explained! Thank you!
@ozfreak269 күн бұрын
Thank you! Great video!
@kennygibbs96279 күн бұрын
They scraped mine but a 2:04 year in a half, clogged again 100%, so they said there's 4 other veins that are open that head up to my brain 🧠. Is this good or not 🤔
@HansGrob12 күн бұрын
Nothing shocking here.
@Dr_V15 күн бұрын
I think I knew most of this stuff 20 years ago, but it's not something a radiologist thinks about very often, so this was a nice quick refresher for me 😊
@DennisBolanos15 күн бұрын
1:25-I’m an undegraduate chemistry major and you just explained it way better than any of my professors! 😅
@KillerKatProductions17 күн бұрын
Now i need to throw the video transcript into AI and dumb it down so i know what was said!😂
@MaveRick-prepper20 күн бұрын
I lost my sense of taste and smell about 3 months ago. My biggest concern is eating food that has gone bad and not being able to tell that it's bad.
@wallrider419421 күн бұрын
14:18 crush it.
@wallrider419421 күн бұрын
9:57 bacteriophage 💀
@afar582926 күн бұрын
Id be curious if Ivermectin would work on long COVID.
@mhuraic28 күн бұрын
I have not been able to taste or smell for 3.5 yrs. Do you still consider that temporary??
@aleksandrac93357 күн бұрын
Holly shit
@mykhailoriabtsev8982Ай бұрын
There is an error in the video. At 6.50, he says that all the air is evacuated out of Crookes tube, but if that is so, it could not work. Crookes tube works because there is some very low-pressure air left inside. It is being ionized by a high voltage applied to two electrodes, and only because of that does it have electron flow. The thing is that thermionic emission is not used in Crookes tubes; for that, you need a heated cathode, like in modern CRTs. Without that, conducting current through a really good vacuum is impossible.
@TheHyperMDАй бұрын
saw your amazing videos when I was a med student and keep coming back to it when im a Neurologist resident! any ideas what can cause multiple lesions in the brain with mixed enhancement? some hyper some not. THANK YOU!!!
@DoctorKliozeАй бұрын
Site unseen, I would think the most common entity would be MS with a mixture of active and quiescent demyelinating plaques. Any history?
@TheHyperMDАй бұрын
@@DoctorKlioze THANK YOU FOR THE REPLY! yes, 41yo female with STAT3 gene mutation (Hyper IgE syndrome, but w/o elevated IgE/Eosinophils) and MGUS.
@AbdiPianoChannelАй бұрын
Higher voltage on TV tube will defiantly produce higher X-ray
@mokydenanАй бұрын
I learned even more than what I initially wanted to know. Amazing video, thank you!
@rogerscottcatheyАй бұрын
Stop calling it "social" distancing. It's just distancing or physical separation. "Social distancing" is turning off your phone, snubbing neighbors, turning your back on friends... And by the way, proven long ere 2020 to be useless
@DoctorKliozeАй бұрын
Easy Francis. If you look at the date of this video, it was actually back in 2020. I agree with you, but that was the buzz word at the time. Can’t go back and change it now.
@rogerscottcatheyАй бұрын
@@DoctorKlioze : My words are to anyone reading. Not directed youwards. Who's "Francis"? 😐
@DoctorKliozeАй бұрын
Bill Murray. Stripes. 1981. 😄
@AaVv-om6kvАй бұрын
🤲🕋💫 allha jllha jalal 🌹
@ezekielbeltran1189Ай бұрын
That was amazing 😮
@davidbiilmeier2295Ай бұрын
Fantastic presentation. Every physician who treats cholesterol will find this video very beneficial.
@ericshea87212 ай бұрын
Dr K. Please comment, there are those that say LDL’s are not the problem. It’s the VLDL that get converted to Small LDL’s that are the problem. They are able to gain access to the artery lining and cause atherosclerosis plaque. Does your labeling’A’ and ‘B’ also follow this small LDL explanation?
@DoctorKliozeАй бұрын
Exactly! VLDL's are the particles that come out of the liver and transport triglycerides and cholesterol esters to the periphery. Once the triglycerides are distributed, the particle becomes IDL and LDL, both of which have a higher relative cholesterol concentration. The smaller, denser LDL particles seem to lodge in the walls of the arteries causing atherosclerotic disease which may be related to the absolute ratio of triglycerides to cholesterol in the original VLDL particle (higher the original triglyceride content, the smaller and denser the LDL particle) I'm going to cover all this in my part 2 video on lipid labs coming up in a few months. Great comment!! 😎
@keyoorgautam64532 ай бұрын
Beautifully explained. I am starting the test in my lab soon. Thanks
@alfonsogutierrez13922 ай бұрын
So hdl and ldl aren't cholesterol, why keep calling thrm good and bad cholesterol?
@DoctorKlioze2 ай бұрын
Awesome question! it’s a little deceiving. Cholesterol is cholesterol. On your laboratory report, you’ll notice that HDL is labeled HDL with a little c an LDL, LDL with a little c. That means this cholesterol is associated with each of those particles. The problem is that number can be deceptive. What’s more important is the number of LDL and HDL particles. That’s why we’re getting away from reporting just cholesterol, HDL and LDL and now moving more towards measuring apoA1 and apoB which are actual markers for both HDL and LDL particles, respectively. I do intend to include this in my part two lecture on lipid labs. 🤛🏼
@alfonsogutierrez13922 ай бұрын
@@DoctorKlioze thanks
@paulelkins4252 ай бұрын
One more point, everyone should get their LP(a) tested once. It's a very inexpensive test at only $20-$30 through direct labs such as Ulta Labs. Your PCP will likely add it to your lipid panel on an annual checkup too, if asked.
@paulelkins4252 ай бұрын
Excellent content on a very important genetic risk factor that fly's under the radar. I'd add that until we have the genetic therapeutics available it's important to minimize all other CVD risk factors, including reducing ApoB. PCSK9 inhibitors are very effective at reducing ApoB and they also reduce Lp(a) by 20-30%. Another risk from elevated Lp(a) is thromboembolic events. There is some data supporting baby aspirin for high Lp(a). However, this should be discussed with one's doctor due to the increased risk of bleeding from aspirin therapy.
@J-Bibble2 ай бұрын
I suffered horrible disability from a single injection of Gadovist (macrocyclic). I developed new horrible neurological symptoms in the days and weeks following the Gd injection (e.g., muscle twitching, burning skin, red spots on skin, pins and needles, electrical shocks) and extreme back, bone and hip pain and fibrous inflexible muscles. I was perfectly healthy before my MRI (it was precautionary and ruled out any issue) and have normal kidney function. So I had no pre-existing conditions. I'm still dealing with this extreme pain and disability 8 months later. Do not allow them to administer this unless it's absolutely life or death, as it's much more risky than acknowledged. So many patients have been permanently injured and there is no cure or antidote to remove gadolinium right now (one is being worked on, so that must tell you something).
@davidpescod75732 ай бұрын
A brilliant video showing how the original simple scanner evolved into today’s incredible machines which are capable of revealing the whole body, inside and out. Many thanks
@Thragginit2 ай бұрын
Best video on magnetism I've seen
@mide86782 ай бұрын
Wonderful presentation! Thank you, Super Team.
@justme1975112 ай бұрын
Never coming back.
@TerryClarkAccordioncrazy2 ай бұрын
I learned a lot about the history of X rays, thank you!
@chinmoy110919873 ай бұрын
Wow.... Beautiful
@renugadevi1053 ай бұрын
Thank you dr
@francishubertovasquez21393 ай бұрын
Are there focused campaign for different states pinpointers and locators, I'm not referring to the United States, only in science point of view, asking to anonymous experts.
@francishubertovasquez21393 ай бұрын
Are there focused campaign for different states pinpointers and locators, I'm not referring to the United States, only in science point of view, asking to anonymous experts.
@francishubertovasquez21393 ай бұрын
No intent to malign any modern treatments. Was the MRI used today pure diagnostic to aid in therapy, how about the push buttons, youve shown me orientation of the science functionality of such, no other other uses ?
@AkgunIlhanIstanbul4 ай бұрын
Amazing clarity :) Thanks a million!
@LulasSong4 ай бұрын
Nothing to do with blood, Neurologist said. Facial paralysis only, left eye and lip, horrible throbbing pain comes and goes under left ear/neck area. Info?🙏😿