Happy New Year to you too! 🥳

Thanks a lot! We’re glad you enjoyed it😊

Thank you for your comment! While I partially agree that the influence of social media should be taken into account, I don't believe it is the primary factor behind this phenomenon. The structure of academic research and the academic system must be drastically changed; otherwise, it is doomed to fail miserably. :)

@@neurosciencebeyond The 'structure of academic research' suffers greatly if and when the future generation of researchers is incapable of concentrating, learning etc. Our culture of dedication for science is both gone and secondly has been oversaturated with unfulfillable expectations. Science is a craft and that requires many years of apprenticeship. What has changed (in some countries) is who pays for it. States pay less and less for the education of their workforce and spend more soaking up the qualified graduates of other countries who have done so. Politicians rather spend money fighting wars (very easy to send billions to others to buy weapons, very difficult to keep the fickle human beings on a straight and narrow track...). Now with migration becoming more of a hot iron globally societies are losing this ability to rejuvenate their workforce (by attracting qualified people that have been educated elsewhere).

I am not aware of such implants. What kind of cognitive function do you think can be addressed with such ocular implants?

@ do you have an email?

@ I was looking at current therapies for depression, anxiety, schizophrenia, seizures and cognitive fatigue. And I did a little research into blindness and various disorders, which led me to looking into Al-driven ocular implants or contact lenses/glasses. The thought being that AI could potentially incorporate sensors which could monitor brain activity in real time and detect abnormal patterns, triggers and could be potentially use those detectable algorithms and then use light pulses, to deliver targeted neurostimulation to aid the brain to learn a new way of responding. Strobe lights sets off seizures for me so I was thinking that a reverse approach would potentially provide solutions. Full disclosure..I’m just a mom and do not have any formal background in medicine or science. Just way too much time on my hands…

@sharonahyde4202 Your way of thinking is incredibly innovative-thank you for sharing! Let me clarify a few things. Sensors capable of electrically stimulating the brain already exist and are used in treating certain neurological conditions, such as Parkinson’s disease. Some of these devices can also record brain activity before delivering stimulation. You might find it interesting to look up Deep Brain Stimulation (DBS) if you'd like to learn more about this. As you correctly pointed out, AI could play a key role in predicting abnormal brain events like seizures. For this to become a reality, though, we’d need a large amount of data from patients to train AI algorithms. While prediction is advancing, the prevention of such events is still quite challenging. Regarding optical stimulation, it works differently. To stimulate brain cells with light, those cells need to express specific light-sensitive ion channels. This approach, called optogenetics, has so far been used primarily in research settings. One clinical trial has explored using this method to treat a specific type of blindness. If you’re interested, you can check out our full episode where we dive into optical stimulation in detail! As for the seizures you experience, they’re likely triggered by different mechanisms than what optical stimulation addresses. Since I’m not a doctor, I’ll avoid speculating about your condition, but I hope this explanation sheds some light on your idea.

In case you still need it: [email protected] :)

:D

@knowledgeckr786 thank you for the comment!

Smartphones proximity sensors NIR-II "under active display" NIR-II used on MINDS by Guosong Hong

Радваме се, че съдържанието на това видео Ви е интересно! :)

Thank you for the nice words @LauravanAgen!

I am glad you liked it. :)

:D

To my knowledge this is still not possible. The whole field with pluripotent stem cells and organoids is still in its infancy. However, there are some publications on intervertebral disks and pluripotent stem cells, maybe you can find this interesting: www.sciencedirect.com/science/article/pii/S0753332224001197 www.ncbi.nlm.nih.gov/pmc/articles/PMC8092931/pdf/i2211-4599-15-s1-40.pdf

She is indeed a top notch researcher! :)

I am not aware of a study looking into this.

I am not aware of a study looking into this.

Thank you!

Hey KG-xf9ew :) Thank you for your comment! Indeed, there are lots of problems in academia. However, I am not quite sure if I understand your opinion/arguments on the topic. Could you please elaborate?

@@neurosciencebeyond I hate to say it, but your reply illustrated my point exactly. You will do well in academia.

Thank you for the comment!

Thank you!

Hi @TLTeo! Thank you for taking the time and effort to write this comment! The topic you've raised is 100% valid and challenging to solve. I believe I discussed it in some previous episodes. We try to increase awareness of many flaws and problems in academia by discussing them in the last part of our episodes (10-15 minutes). Perhaps we should release several short videos summarizing these issues, including the one you've mentioned. If we want to make any change in the field, the first step, in my opinion, is to identify the problems and the reasons for this prblems and start openly dicsuss different ways of solving them as a community.

Hey @servicekid7453 :) Thank you for your comment! Do you have any experience in or outside of academia? It would be fantastic to hear more about your perspective. I also want to remind everyone that we aim to foster discussions based on mutual respect and understanding. Let's keep the conversation respectful and constructive.

@@neurosciencebeyond yes 10 years in academia before I was brave enough to get out. Academia has 3 principal problems, none of which it has any strategy or motivation to fix: i) it is hugely wasteful of talent. We put far too many people through grad school then take bright and motivated young scientists and feed them through a meat grinder. What comes out the other end is mostly burnt out, financially impoverished and hacked off ex-postdocs who are often over qualified for most other jobs and find it difficult to start their careers over again in the private sector. Of course this will never get fixed because PhD students and post-docs do most of the actual labwork that generates data for papers ii) Impact factor was never designed as a measure of quality but it has become the second most important metric in hirings and promotions. Impact factor was designed to help librarians decide what to stock on the shelves - ie pick the journals that are most widely read, since if you have those available your clients might actually use your library and your budget won't get sliced. But it was an easy and quick way to rank people, so hey presto here we are. If one single thing is more responsible for the surge in research misconduct than anything else, it is the need to achieve high impact factors. iii) Funding models are a complete mess. We take lots of very bright people, then underfund all of them and let them fight like rats in a sack for every last penny. It creates perverse incentives to screw over your competitor labs and even your own departmental colleagues. Some people are terrified, some people are numbed by it, some take a kind of sadistic glee in it but it's still mostly a horrible toxic manipulative contrivance. The absolute worst colleagues I have had, 100%, were in academia. No-one in the private sector I've worked with has ever come close to matching the nastiness of academics I have known. When anyone asks me about doing a PhD I ask why and in 9/10 cases I advise them not to do it. My own supervisor advised me against going into research. I'm proud of my work and I never thought I would be remotely important or well-known, I just wanted to do some interesting experiments and get it published and cited, but I paid a really high price for it in terms of my health and family life

Given that there are not enough positions available in academia to cater to all the graduates in the first place; it's necessary for the graduates who are not placed to allocate themselves elsewhere. I don't know how many phds become farmers; but there are theoretically market conditions that could make that happen.

@@gilian2587 if the tenured positions in academia were awarded on merit I might agree with you, but they aren’t. Academia is rife with charlatans, bullies, liars and cheats. Many of them get tenure despite their appalling lack of integrity. ethics and decency.

@@servicekid7453 Thank you for your valuable comment! Somehow, this comment escaped my radar, and I’m just seeing it now. I’m sorry to hear that you’ve struggled throughout your academic life, but I’m glad to hear that you’ve found fulfillment elsewhere. I completely agree with the three points you mentioned. The question I’m trying to answer through all these interviews is: how do we fix it? And is it even worth fixing, or would creating a new system be easier and more effective? I love science and scientific work, but the way science is conducted needs to change immediately.

Hey @fano503! I am glad that you like our content. Thank you for the kind words!

@user-iq2yp1dn1q, thank you for your comment! So, you're suggesting a separate degree that would specifically prepare young scientists for tenure-track positions? If I understood you correctly, I think you raise an interesting point. The idea behind a PhD is indeed to support academic careers. However, the reality is that the 'supply' of PhD graduates far exceeds the 'demand' for tenure-track positions, which is one reason many well-trained young scientists decide to leave academia. Perhaps a separate degree aimed specifically at preparing young scientists for the job market outside academia would also be valuable. Such a degree could focus on industry-relevant skills and provide a clear career path for those not pursuing academic roles. Of course, there are many problems in academia that need to be addressed, and this is just the tip of the iceberg. Your suggestion opens up an important conversation about how we can better align educational pathways with career outcomes.

@francoisperrin7397, interesting perspective. Have you worked in academia? :)

@@neurosciencebeyond I worked in academia and in industries as well. I've seen this happening to many colleagues as well.

Thank you for the 'meaningful' comment! :)

@neurosciencebeyond I'm sure you have other clips that have content worth listening to. But this wasn't it.

Hey @shanemccormack8212, I'm sorry to hear that you're experiencing this. Sleep disturbances can indeed have many different causes and don't necessarily mean you have a neurological condition. As you may know, It's important to consult with a medical specialist to get a proper evaluation and support. Take care!

Hey @danderas6377, thank you for your comment! Do you also have experience in academia?

Thank you for your comment!

Thank you!

Thank you for watching!

Yes. Imagine you develop a new drug for cancer and you wanna see if it's safe. You can model in the computer every known receptor site to see if it has a chance to dock at sites of toxicity. If So, you never even need the animal model to rule it out as not a good drug. But even if all the computer tests show no obvious issue, then you still have to actually test it on a living thing. It could turn out to be toxic through binding to some new receptor target we never discovered before. That would never show up on a computer. However, once that is discovered it could be modeled in the future. And future drugs would be ruled out on the computer stage, by being able to det Ct that before ever going in an animal. I mean we could just jump straight to injecting experimental drugs into people lmao? Computers help by ruling out things that have a high chance to be dangerous. But it doesn't know everything. There's still plenty of chance it could have ubforeeen consequences. Computers first, then test tubes, then animals, then people, if no problems arise at any stage.

In the full episode you can learn a lot more about animal experimentation in research. :) Check it out here: kzbin.info/www/bejne/aKexiKKieNhkiaM

Thank you for the kind words!

Great question! However, we did not discuss this particular topic. If I meet prof. Moser soon, I can ask him this question.

Thank you!

Probably around 25-30 million years ago (www.pnas.org/doi/full/10.1073/pnas.0407270101). However, this is a 20 years old study and there might be new data on the topic.

@@neurosciencebeyond thanks for the paper link

Hey @exploreyourdreamlife :) Thank you for the kind words! I am not aware of such software that is able to animate dreams but probably in the future due to the rapid development of neuroscience and AI we might be able to do something in these lines. :)

Good Question! :D We will ask him next time! :)

You’re welcome!