3 common interview questions on Forced Degradation

This video will help you to answer three questions on forced degradation
1. Why do you conduct forced degradation?
detailed video link: • why conduct forced deg...
2. What is the mass balance?
detailed video link: • What is mass balance a...
3. What is peak purity?
detailed video link: • Peak purity measuremen...

[@achyutjagdhane9683]

Very relevant explanation, in industry no one able to explain such a deep explanation , thanks a lot sir

[@sagardhimdhime6771]

Sir,. Nobody can explain like ....u explain in very simple way.... concepts are completely clear ....thanks...

[@rohinikumar7065]

Sir you explained in very good manner it is useful to lot many persons who so ever no idea on deep knowledge on respective subject and their work because of your videos lot of people facing interviews easily thanks a lot sir

[@ajaybedadurge9546]

This type of explaination is need of the hour...your voice your word very accurate sir...thank you for your efforts to explain in very good manner

[@kharadiritesh1419]

What do when mass balance is not achieved?

[@manalidave2145]

Great explanation sir

[@jigarbhatiya9621]

Thanks to clear my doubts about forced degradation study. Great sir..

[@tej9763]

If product in base NaOH hydrolosis peak split happen in but we achieved mass balance if peak purity fail also we can submit the fd data

[@yogesh.r.pagareshirdi7483]

Dear sir, Thanks a lot for making this video, now i have clear my doubt that is whats stability indicating method, after lots of reading i didnt understand the exact meaning but after watching your video, now the concept us clear, thanks a ton. I will definitely watch your all video, it helps me lot for building my career.

[@chilakavenkatraju2498]

Very informative sir

[@rashmishirsath2436]

Thanks sir you are the best

[@krishnakagale307]

Sir how can we predict possible degradation products in acidic, basic, or oxidation conditions based on structure of the molecule?

[@tinkalpatel5013]

Sir can you answer this question in video

[@kodandaramudu8786]

Nice information

[@pharmagrowthhub3083]

Thanks

[@gonchalaveerababu7587]

THanks sir

[@srinivasp8882]

Good evening sir in degradation which guidelines based perfom

[@bakyarajvaithilingam8641]

Intrinsic stability not understanding

[@tadalavenkateswararao2090]

Sir if assay and rs different methods than forced degradation study atatime perform assay and rs now assay sample preparation taken from rs sample and dilueted to assay diluent is it correct or not

[@haribabu7807]

Correct

[@tadalavenkateswararao2090]

Limt how mussh sir massa balance

[@PRAVEENKUMAR-xb6sb]

as per company to company varies 5 % to 20 %

[@haribabu7807]

As per sop 20% U can r perform minidegradation only cause past degradation can not give mass balance

[@jayakumaryerukolu]

There are no guidance says about limit for mass balance and industries generally follow NLT 95% as limit.

[@tadalavenkateswararao2090]

@@jayakumaryerukolu and another question in rs method standard preparation with respect to highest induvidual unknown impurity level prepared why?

[@amitpathak2259]

+ 5% and -5%