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- Fungi introduction
- Types of fungal infections - Mycoses
- Targets for antifungal therapy
___ CELL MEMBRANE ___
- Polyenes: Amphotericin B and Nystatin
- Azoles:
-- Imidazoles (Miconazole - Clotrimazole - Econazole - Tioconazole)
-- Triazoles (Fluconazole)
- Allylamines: Naftifine
___ CELL WALL ___
- β-glucan synthase inhibitors (Echinocandins): caspofungin
___ MITOTIC SPINDLES ___
- Griseofulvin
___ DNA ___
- Flucytosine
Combating Fungal Foes: Exploring the Medicinal Chemistry of Antifungal Drugs
Beyond the Bathroom Shelf: Unveiling the Science of Antifungal Medications
From Molecule to Medicine: A Look at the Medicinal Chemistry of Antifungal Agents
Fungus Among Us? How Medicinal Chemistry Battles Fungal Infections
The Weaponry Against Yeast: Unveiling the Chemistry of Antifungal Drugs
Can We Outsmart Fungal Infections? Exploring Medicinal Chemistry Solutions
Targeted (assuming some chemistry background):
Targeting Fungal Weaknesses: Mechanisms of Action in Antifungal Drugs
The Design of Antifungal Agents: A Medicinal Chemistry Perspective
From Bench to Bedside: Developing New Antifungal Drugs through Medicinal Chemistry