A Man Took 1176 Ibuprofen Tablets In A Month. This Is What Happened To His Kidneys.

All references listed below
Portuguese translation and dub: George Frederico
Spanish translation and dub: Cenzontle Voices, Inc. CDMX
Spanish Medical Review: Dr Araceli Morga Vera
Music by R. Prince, rearranged
Music by ‪@Lifeformed‬ lifeformed.ban...
Music by T4N3 / t4n3
Some images by Getty Images
These cases are patients who I, or my colleagues have seen. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. I do not give medical advice over the internet.
References:
Gastrointestinal injury associated with NSAID use: a case study and review of risk factors and preventative strategies. www.dovepress....
Oesophageal perforation following ingestion of over-the-counter ibuprofen capsules.
www.cambridge....
Esophageal ulcer induced by ibuprofen tablets. www.ncbi.nlm.n...
Kidney damage from non steroidal anti-inflammatory.. bpspubs.online...
Gastrointestinal injury associated with NSAID use: a case study and review of risk factors and preventative strategies. pubmed.ncbi.nl...
Nonsteroidal antiinflammatory and acute renal failure in elderly persons. pubmed.ncbi.nl...
Many People Take Dangerously High Amounts of Ibuprofen. www.reuters.co...
Does Ibuprofen Come in 1000 Tablet Bottles in America? Can the buyer finish it? www.zhihu.com/...
NSAIDS: Acute Kidney Injury in UpToDate. Retrieved January 2023.

[@chubbyemu]

Happy new year! In 2020, KZbin discontinued community contributions for subtitles. I had so many great contributions from people and universities all around the world on my videos up to that point. Today, I am trying something new. There are Portuguese and Spanish subtitles, and audio dub tracks on here. You can access them by accessing settings on this video (3 dot button on mobile or the settings cog in web browser), and I hope to have more this year. Hope you enjoy and learn from the video! Thank you!!

[@lolita_cat]

do y'all prefer watching chubbyemu dubbed or subbed?

[@Jotchua]

Love your content Emu

[@ValiskiI]

how on earth did this guy think it was a good idea to take 1176 ibuprofen tablets in the span of a month

[@tictac6963]

i love you

[@Jotchua]

@@ValiskiI he’s going for a world record

[@EnragedTiefling]

"Gotta finish this whole bottle of pills immediately" is an interesting and alarming take.

[@egg_addict]

sure is, especially for over the counter stuff.

[@Zach0451]

Why take them every few hours when you can finish them all at once? We are about efficiency here.

[@iagas9]

Seems like this guy had some neurological/psychological problems already

[@Jrock420blam]

@@Zach0451 faster you take them faster you're cured. makes sense, same people who bake cakes at 1000 degrees for 2 mins rather than 350 for 20

[@AnymMusic]

@@Jrock420blam exactly. Quality German Engineering at its finest right 😂

[@keenanlarsen1639]

It is actually unbelievable to me that people like this not only exist, but live long enough to make it to adulthood.

[@DzinkyDzink]

You can blame the ER for not purging the genefond.

[@Dragnerve.]

they also reproduce leaving more stupidly raised offspring.

[@MikeHawkhehe]

Try working in a pharmacy. I'd say over half the patients don't even know what meds they're taking

[@dinahbrown902]

Doctors are preventing the thinning of the herd by natural selection 😜

[@chriswalford4161]

@@MikeHawkhehe: that’s either pretty frightening, or it shows absolute blind faith in what the prescriber intends.

[@mythicdragonrider3578]

I honestly have no idea how some people don't tell their doctor about the 1000 ibuprofen tablets they have taken when being admitted for severe symptoms. Whenever I go to the doctor with mild symptoms my anxiety makes me share every medication I have even thought of taking in the last two months

[@markiangooley]

It’s so tempting for me to be nasty and say that such stubborn stupidity deserves its natural punishment, but I have my own peculiarities and I could get myself in a different sort of trouble through them.

[@thedarkduchess7556]

As somebody with a chronically bad memory as well as a chronically bad body, it's hard to remember every medicine I take 😅 To be honest, i'm not even that bad off and some people have to take WAAAY more than me. Also as somebody who's had family who has done something similar this, Ibuprofen is something a lot of people think of as a mild pain reliever and with the bottle saying you can take 1-3 every 4 hours that it can't actually hurt you. When you're in a lot of pain you are just glad you aren't hurting anymore and a lot of the time they just don't think the "safe pill" is actually hurting them

[@TheNelly77]

It's quite easy to overlook pertinent details when one is in pain - and even easier to forget that fact when you're NOT in pain and commenting online.

[@carolgibson-wilson4354]

@@thedarkduchess7556 Ibuprofen says 2 tablets or capsules every 4 hours. acetaminophen days 2 every 6 hours. My granddaughter, at 20 misunderstood her Dr. and took 6 acetaminophen every 2 hours for 3 days. When we found out she was taken to ER. Fortunately no damage but now she takes a printout from the Dr. to refer to.

[@hyperturbotechnomike]

Stomach ulcers and perforation caused by NSAR can happen even at regular doses. A friend of mine took 200mg over 7 days and had a stomach ulcer, so he had to take Pantoprazol

[@Gypsy_unbound]

I don't understand how some people make it in life. This person is one of them.

[@deano_bites]

Some people have 1 brain cell and walk the streets

[@nathaneastman2268]

He didn’t make it though

[@KDYinYouTube]

because being success is not about brain, its all about luck

[@tsurugi5]

@@nathaneastman2268lol

[@christineknippelberg3975]

@@nathaneastman2268yes he did

[@nicholasagnew2792]

When the pills got stuck in his throat I half-expected him to wash them down with more pills. This man is truly something else.

[@pablolacruz2652]

Yeh, a real genius.

[@VulkanYT]

Literally thought the same lol

[@tu1469]

😂😂😂

[@fluminesesoc]

Lol 😂

[@arielbatista7ify]

Me too😂😂

[@Fire-Rabbit87]

Ibuprofen overdose is a terrible way to die. My surgical tech instructor told my class about her neighbor's daughter that tried to commit suicide by taking two whole bottles of ibuprofen. She was taken to the hospital too late and of course she didn't die right away. By then she didn't want to die anymore, but there wasn't anything they could do for her and it took weeks for her body to just slowly shut down. So sad 😢

[@WinryGames]

The same happens with paracetamol overdose… it’s horrific and devastatingly sad

[@bvllseye4068]

Whatta sass

[@AGuy-vq9qp]

@@WinryGamesparacetamol takes quite a while before it gets lethal.

[@WinryGames]

@@AGuy-vq9qp it does, but it still the same as in - you don’t die in your sleep, you instead wake up not wanting to die, but then it’s too late and spend a week in agony as your body shuts down 🙁 it’s awful..

[@Irish_Georgia_Girl]

That's horrible!

[@beardiemom]

Something else to mention: Taking painkillers to allow you to exercise without getting that pain checked out first is a bad idea. Pain is there for a reason: It tells you that you are hurt. If you ignore it or push through with painkillers, you could cause permanent injury that might make it impossible for you to do any type of physical activity in the future.

[@SageArdor]

Unfortunately, one of my college track teammates learned this lesson the hard way. Kept pushing through pain in his legs with ibuprofen instead of letting it rest, since he was the "star runner" of the team. Didn't take long before a leg injury ended his career.

[@SOSPainting]

So so true. I had achilles tendonitis and didnt know anything about injuries. So i just kept running until eventually I could barely walk. I wish I had known that the pain was NOT gain in this situation. Now i may never run again 😢

[@beardiemom]

@@SOSPainting Damn, I'm sorry to hear that. That sounds awful :(

[@thubakabra]

@@SOSPainting I am sorry to hear that. :( I had a knee problem for a long time and once I got mad in the middle of running that it hurts and I kept running until I could barely walk home. I couldn't walk normally for weeks and I learned that I had to have a different approach on this. A friend suggested a book "born to run", and it made me realize that the way I was running was putting a lot of pressure on my knees. After I was able to run again, I experimented a lot until I learned a new way and I don't have that knee problem anymore. I hope you'll be able to run again. Just don't be hard on yourself.

[@Sorrowdusk]

Good point.

[@de341f6]

Taking a thousand of anything is absolutely nuts

[@willischwabe1324]

A thousand youtube videos!

[@yocats9974]

I have taken a thousand grains of sugar in my tea over the course of a single month

[@Marce_mc]

So, can eating 1000 grains of rice kill me?

[@LaughLagoonTV913]

My eating 999 iboprofenos: It's also ok- 😫🤢💀

[@djdaniel4205]

Ah damn, I consumed more than 1000 ml of water. Shyte.

[@Redwhiteandtired]

I almost bled to death in 2020 on a cross country road trip where I was constantly taking ibuprofen to get rid of headaches while driving and I would drink alcohol heavily at night. I had black stool for almost 4 days before I went to the hospital where I was informed that I had lost almost a 3rd of my blood from an ulcer in my stomach and needed an immediate blood transfusion. My advice is never ignore something like black stool and be mindful of what you are putting into your body. Stay safe y'all!

[@patiakreles]

Always take a good look at your stool before saying goodbye.

[@nathanmcbow158]

Ouch, also bear in mind that Darkish Stool is also a symptom from the usage iron tablets, typical medications if you are a blood donor.

[@TesterAnimal1]

Or know what drugs you are putting in your own body, and what their effects are.

[@CrashBoomBang78]

Or just don't fucking drink whole being on medication??!!

[@maestro9765]

Also, alcohol and NSAIDs, a dangerous combination.

[@brittanyjoson3630]

Thank you SO much for pointing out how ibuprofen doesn't lose its efficacy. As someone who has chronic migraines, ibuprofen is the only medicine that makes the pain manageable. I was really worried that it will lose its effect like people said but it's comforting to hear that it doesn't at all.

[@ammonil1261]

Honestly same, I hardly ever take it but I still sometimes worried about that, especially if taking one or two didn’t get rid of a headache

[@bou222]

I thought the same thing. It is the only thing that I can manage my extreme tooth aches with. I was taking way to much before because I was in desperate pain, sometime up to 18 200mg tablets a time, but I made sure that was only every 36 hours usually. I thought f I took more than that, faster than that it wouldn't take care or the pain anymore since a few times I had taken it too soon and it seemed to lose its effectiveness. That was just my experience though. I have since had pancreatitis and a scared liver diagnosis most likely the result from taking to much Ibuprofen, significantly lowering my protentional lifespan. Thanks for the knowledge and making this video ChubbyEmu. I wish I knew this years ago.

[@havocdudeman2925]

so you dont use anything stronger than ibuprofen? ONLY ibuprofen helps? i doubt that 100%

[@bou222]

@@havocdudeman2925 I used to be a heroin addict, so I was afraid to go back to using again even though I knew it would help me. 8 years sober this last november.

[@sindicta5757]

@@mattb4640 if I go to bed every time I get a serious headache I'll be bedbound

[@Beaumiroir]

I come from a country where the biggest box of Ibuprofen you can buy is probably 24 pills so yeah when I moved to the US and saw bottles of 500 in 3-packs I was shocked. Even if people don't misuse it as badly, it encourages self-medication for chronic pain that may need to be looked into. That's even worse with acetominophen knowing how few tabs can make a lethal dose.

[@poisonparadox92]

They come in bottles that big because we can't afford to have it fixed. Lol

[@grmpEqweer]

@@poisonparadox92 Exactly!

[@hollyshouse928]

I'm in Canada, I think the most I've seen was maybe 36? I've never bottles as big as the video

[@Thanatos2996]

I find it odd that you guys have such small bottles. I can understand not having the 1000 packs, but 24 is tiny.

[@dexterstudio480]

USA is an animal farm, how can you sell overthe counter drugs in such quantities in my country such amount are only in hospitals where they divide it to small doses

[@tomaszfalkowski7508]

It blows my mind how some people don't have common sense. Since I was a little kid I was always scared to take pain medication because of how well it's known that high dosages are toxic to the kidneys and liver.

[@jdlech]

This guy sounds like my father. As an aging cement mason, he would come home hurting. He would take a hand full of ibuprofen, then amplify the effect with a 40 oz bottle of beer. He would do this 5 days a week for years before he could retire. In retirement, he had no idea why he was having problems while keeping his past drug abuse a secret from his doctors. A doctor figured it all out only when he sat down alone with my mother and listened as she explained all his OTC drug abuse.

[@andreaberryman5354]

What is WITH people TAKING so much?! Good grief! An ex of mine ruptured his guts due too Ibuprofen and alcohol every night to avoid knee sugeries.

[@aazhie]

@@MadeInTheAbyss I suppose it's at least harder to truly OD on normal cannabis and helps that it knocks you out if you overdo it xD

[@jamesfritzinger147]

He had chubbyEmu merch so he should have known better

[@jamesfritzinger147]

I think the only way it is "amplified" is if it was Advil pm or Tylenol pm for insomnia

[@Dang3rMouSe]

I've got stomach ulcers for this very reason. Didn't take as much as you'd think but I learned the hard way. I think it was more so the continuous use to manage pain

[@maelentrewela2395]

This is why, when my patients claim to "not take any medications", I ask about Tylenol, ibuprofen, and supplements. Most seem to feel that, because there wasn't a script, it is not medication and does not count. I always write down everything on a sheet of paper when seeing a doctor myself to ensure they have everything I might be taking or have taken recently.

[@BtheLee11]

i see so many APAP and ASA poisonings at the ICU, and a lot of them are young people. Mainly their ignorance to how medications work and whether or not that trade brand is the same as that generic medication so they effectively double up on their dosages to very toxic levels

[@djinn666]

Supplements? As in vitamins?

[@ProjectfullCurcit]

@@djinn666 yes and more. Minerals, amino acids, protein anything that you take that is not food really.

[@aiaioioi]

but supplements aren't medication tho? like they literally state "not a medication, a biologically active supplement" in my country when advertising vitamin complexes... upd: of course i'm not talking about stuff that improves performance like anabolics/any other stuff that clearly isn't just a supplement that you are supposed to get naturally but for some reason you don't so supplements make up for that

[@TheSCPStudio]

@@aiaioioi bruh it’s common sense. Anything you take can alter your body.

[@reese8468]

His "entire course of meds" thought might have been excusable if it wasn't A THOUSAND PILLS IN A MONTH. This man is truly something else and I'm amazed he survived

[@angelagendreau3586]

Yeah, it's not antibiotics. He didn't need to finish the bottle. The things people come up with.

[@jonathanpowell613]

He's VERY lucky to be alive! I heard that ibuprofen can kill if too much is taken.

[@tailrj]

Who said 1,000,000 pills 💊

[@JackO024]

Might want to try READING THE BOTTLE!😂

[@altingashi3927]

Dude I take that now and have been for 2 years Not even kidding

[@joshuabodde.6935]

Medical student here. I was so intrigued that I actually knew what this was and I could actually run a diagnosis!

[@user-zm7zl9lc6j]

Im pre med and Im excited to start actually understanding this studf

[@buttermilko]

Thank u for studying to help people that’s so cool

[@Munchkit]

Im 13 and I wanna be a Trama surgeon!

[@Shellyshocked]

Please don't dismiss patients who have a history of drug abuse. I'm now suffering the consequences of numerous doctors not believing me and thinking I was drug seeking when I actually had legitimate pain and a reason for it. Now I'm trying to play catch up and try not to die because doctors didn't take me seriously. If my medical conditions had been looked into years ago I wouldn't be suffering now. I was told take Ibuprofen you'll be fine for over 25 years.

[@angelinebrasier9882]

Well done, you! All the best with your studies!

[@elainechan7155]

I can't believe SB could take 1000+ ibuprofen in a month and STILL can have a recovery. Good for him 😮 and good job, doctors!

[@nevertheless872]

I have no idea how he survived, his kidneys shouldn't have been able to regulate all that medicine it can only handle but so much medicine he was truly luck, God was with him.

[@tuvoca825]

Damage can be long term even if it isn't immediately apparent.

[@Anonyme-ng6ue]

@@tuvoca825 Yes but i think they are saying that you are DEAD when you take 1000+ of ibuprofene

[@circleinfinite]

good for him, bad for natural selection... sorry joking...

[@monkeybarmonkeyman]

You think they had a full, healthy recovery? I didn't hear that stated, just that they recovered.

[@kendrapoppino7223]

I’ve dialyzed quite a few NSAID abuse patients. Some got their catheters removed because kidney function returned, some exchanged them for fistulas. It never ceases to amaze me how people equate over the counter medications with absolute safety. Everything, even water, is dangerous when consumed in excess. A very simple lesson that should be taught in childhood and could save lives at best, and improve lives at worst.

[@MadsenTheDane]

I was admitted not long ago because i had taken a toxic dose of Paracetamol and Ibuprofen, not because i wanted to, but i live with extreme tooth ache, and the pain prevented me from sleeping and time got mixed up for me, so i ended up taking more than i should in desperation of pain relief. I know that painkillers are not to be played around with, but people can also make mistakes in desperation

[@sakshishyama]

That's why we were taught since childhood....anything in excess or more than necessary is harmful ....not just medicines but literally anything in life .

[@kendrapoppino7223]

@@MadsenTheDane that sounds like the result of a broken healthcare system. I understand completely that people make mistakes, but lack of knowledge and understanding play into that as well as the inability to access the medical help and medication necessary to prevent those mistakes.

[@MadsenTheDane]

@@kendrapoppino7223 I agree that a broken healthcare system is in place, but no where in the world has i perfect, and even in countries with "free" healthcare such as mine, teeth are not covered. Even tho it has been proven time and time again that bad teeth can impact your life just as much as anything else can.

[@RobbYarber]

@@MadsenTheDane That's why I keep a notepad file on my computer where I write down what medicine I take, how much of it I took and the time I took it at.

[@Jotchua]

If there is around 30 days in a month, 30 divided by 1176 is 39.2 tablets per day, meaning this man ate 39 ibuprofen tablets per day and not once thought “yeah, maybe consuming almost 3 ibuprofen tablets per hour isn’t that good for me”

[@jhoughjr1]

well he trusted "the system" a bit too much as opposed to thinking for himself. Dunno how one owld be conditioned to do that.

[@Lil_Harvard]

@@jhoughjr1 The system?

[@IncognitoGameplayer]

@@jhoughjr1 which "system" is telling you to take 1k of tablets?

[@tryingtoart264]

The simulation

[@magicarpex6100]

Natural selection my friend

[@ArthurKhazbs]

Oh my god. Whoever aligned Gabe Newell's portrait with Dr. Bernard's face for that one frame at 9:07… Thank you, this was amazing.

[@shavenyak1]

I know it's way late, but I noticed this as well, very cool!

[@mezzimilku9711]

Bruh it took so long to find a comment mentioning this

[@finnoleg2712]

@@mezzimilku9711 Same here

[@assburgers3457]

This is awesome to see you representing that chronic medication abuse is also dangerous, not just acute

[@gayusschwulius8490]

I would go as far as saying that, when it comes to non-prescription medicine, chronic abuse is much more dangerous than acute one. It's pretty hard to kill yourself with Ibuprofen acutely, but you can easily tank your kidneys if you abuse it chronically.

[@maschaorsomething]

@@gayusschwulius8490 Oh no, I usually take a maximum of 4 Ibuprofen a month because my period pain is so horrendous, it leaves me a crying mess just rolling around the floor. Hope my body will forgive me!

[@gayusschwulius8490]

@@maschaorsomething I was talking about chronic ABUSE, not taking a few tablets every now and then :D

[@Kriegerdammerung]

I yelled at the screen "please, use water alone!!" :O

[@ConsecDesign]

i dunno, i think it's pretty acute

[@PsychoticRainbows]

I'd like to note that even "proper" use if Ibuprofen can cause serious GI injury if you're using it daily for a long time. I followed directions perfectly, but I also used ibuprofen for about a decade, every single day, for chronic pain. I was hospitalized for three days a couple months ago because I caused moderate GI hemorrhage. It was one of the more painful experiences of my life, and it was also pretty terrifying.

[@etherraichu]

I did the same thing, but for a shorter period of time. I only had a moderate ulcer too.. But something must've happened because one day, I just couldn't stand up. it got very big very fast. I don't remember the next six hours, my memory started up again only after the second transfusion. I just remember being in the ICU with a doctor asking me why there was metal in my colon.

[@assetaden6662]

True, Ibuprofen is not meant for long time-consuming, only short-term, since it says in the "how to use" paper its ability to cause internal bleeding.

[@907buschmin2]

Try cannabis drived CBD oil. You'd be surprised on how well it works compared to ibuprofen when it comes to aches n pains

[@Kksaeyi247]

My Mom is a nurse and she'd never let me take an ibuprofen without something to eat first, saying a water isn't enough, and that's on very limited doses.

[@mycosys]

@@assetaden6662 not at all true, i have been on it for years under the supervision of a teaching professor, but i also take medication to protect my stomach.

[@Tinil0]

Oh man, let me tell you, as a chronic pain patient...this story hits extremely hard and familiar. I think most of us have had some experience on the OTC pain reliever merry go round to some degree, learning the problems with each and ultimately being miserable until we can get stronger stuff from an actual pain clinic. It's so, so, so easy to slip up taking pain relievers because pain destroys your mind like nothing else.

[@_mariri]

This. When it's at its worst, you'd really do anything to make it stop. :') I hope that you're holding up alright yourself btw, OP. Chronic pain really fucks with you, and that's an understatement.

[@jhoughjr1]

as someone with crohns i concur.

[@Liusila]

Very true. And the sweet release of the pain finally dissipating just programmes you to seek that ease at any cost.

[@primrose6794]

I've been suffering with severe headaches for the past 7 years and it's impossible for me to do anything since if I try to it causes me to collapse to the floor. Even specialized pain medicine for headaches don't help, and OTC doesn't either.

[@mitchellbailey4906]

I feel ya man. I have done it but fortunately I stopped and decreased my dose when I started having frequent bad heartburn.

[@AuraBloodrose]

He is extremely lucky he didn't get a bleeding ulcer in his stomach that day he took 28 tablets. My grandfather nearly died in his 40s because of ibuprofen, if you take a lot of them with an empty stomach is can cause ulcers, and in his case he was a mechanic ex army man. So pain was a constant for him

[@92up7]

he did...

[@SweetLittleAki]

I suffer from chronic migraines, and I've been using Advil liquid gels since I was 6 to fight them. I get paranoid about having to take 4 tablets spaced out in a day during real bad episodes, and this mad lad's guzzling them down in the hundreds.

[@scull0234]

Yeah, I get migraines around 5 days a week, and if I take tablets more than 10-15 days in the month I have intense stomach pains for weeks, so now I basically don't take more than once or twice a week

[@WorthlessWinner]

yeah, I've been trying to ween myself off of 2 paracetamol tablets a day since i know it can lead to problems in the long run. I should still ween off, but at least i'm not 40 tablets a day lol

[@scull0234]

@@WorthlessWinner yeah, still be careful, I'm going to see a doctor about it, hope I can get some health

[@bobjoe3492]

This dude was taking nearly 2 tablets EVERY hour for a whole month

[@erilynmorgan6683]

if u take too much ibuprofen for too long u can actually get withdrawal headaches. happened to me, i was taking like 6 a day, 4 days a week

[@dapope5440]

this is the man that you read about in math problems

[@Shaunster1995]

Mike took 7^3 pills then he added 2^8 pills. How long (in minutes) until Mike is in a coma?

[@nameredacted7622]

I honestly wonder how such people function. I mean if you are so careless with medicine, something the majority of people are wary of, I wonder what other aspects of life he was so careless in. Did he think dogs only lived for a month because he kept bringing them home but never realized they need food to live? Did he wash his dishes with bleach? Did he hear about rare steak and think you could just eat it out of the package raw? Did he learn that you build muscle by causing tears in the fibers and start cutting himself? With such people anything is possible.

[@gamejunk2707]

😂😂😂😂😂

[@YourDadsOnlyFan]

@@Shaunster1995 "How old is his mother?"

[@NewMateo]

Q: Mike Took 1000 ibuprofen in a single month. How many of his 2 kidneys survived? A: Zero Kidneys. Mike is now on dialysis.

[@kakeyluvsu]

Can you imagine the frustration I felt trying to explain as a nurse, to a mom, that I cannot administer ibuprofen in more frequent doses to her child just because she wants the fever to be gone instantly because of all these dangerous side effects? It’s like she didn’t care.

[@smoothie3993]

My mom had a hard time explaining that to me, difference being that i was a 6 year old at the time. It amazes me that there are people that dumb having kids and driving.

[@The_Kirk_Lazarus]

You should explain to her that the fever helps the immune system work better because the enzymes function maximally at a higher temp and lower pH.

[@numberpirate]

@@The_Kirk_Lazarus Um no, the bacterial or other pathogen's enzymes fail to function at the higher temp. Think about this evolutionarily..... Would it be easier to evolve higher temps via Interleukin production or to have higher temps as well as differential enzymatic function based on temp and pH all co-evolving concurrently especially when those same enzymes need to function at normal physiological temp and pH? Okam's razor applies.

[@numberpirate]

Why are you not suggesting switching between ibuprofen vs tylenol/paracetemol? Both are equally potent antipyretics and both have different mechanisms of action. Obviously no aspirin due to Reye's. NSAIDS=COX2, Tylenol=endo-cannabinoid system.

[@The_Kirk_Lazarus]

@MB Taber You're incorrect. The human body's immune system functions more effectively to fight off bacteria and viruses at a higher temperature and lower pH. Research has not definitively proven that acetaminophen acts on the endocannabinoid system. However, acetaminophen does have COX-1 and COX-2 inhibitor activity.

[@JustMeUpNorth]

this is just one of the reasons why most stores that sell over the counter medicine here in the UK limit the amount you can have. Ibuprofen is usually a max of two packs of 16 tablets. No huge tubs of 1000 pills here. People still overdose, sadly, usually by taking a different brand of medication and not realising it has the same active ingredient in...

[@danb2936]

This video is what EXACTLY happened to me about 8 months ago.... I was having 20 to 30 a day for years... but it finally took its toll apart from my kidneys were not affected.. Almost died due to huge blood loss..over 2 litres. And it's easy to get hold of 96 ibuprofen in pharmacy's without questions at all.. especially asda or boots etc... I'm from UK too ❤

[@mechwar31]

This video is going to blow so many minds in the field of sports medicine and military medics, because I have heard endlessly that "you can take as much ibuprofen as you want there's no negative side effects." Or " your body can only use about 800 mg every 8 hours, the rest just filters out through your kidneys and urine."

[@ravencrovax]

Ranger candy/jump pills as we used to call them. 800mg tabs of ibuprofin. I knew some guys in my unit who used to take 4 of them before jumps cause their knees were so messed up from running every day and then jumping out of planes.

[@allegorx58]

BRO no one NO ONE says that about IB with the assumption that you’d be so incredibly brain dead that you’d consume 40 tabs a day when the label and ever physician ever clearly indicates a TENTH of that as the max daily dose wtf are you even talking about

[@mechwar31]

@@beantheirishsetter Oh man, that reminds me of like one of the goofiest injuries I've ever seen. It was range day, so of course we're all climbing up on the back of the five ton to drive down to the range. One of the kids in my squad was halfway up into the truck when he slipped, on the way falling out of the truck his wedding ring got caught on something. There was this pop noise. Anyway, kid climbs back into the truck and says "Hey Sarge. I think I broke my finger." Asked if he wanted to go to the hospital, and like a proper little grunt. He said "No. I want to go shoot." A few minutes down the road. He pipes up again and says my finger is really starting to hurt. I look at him and sure enough his hand is bleeding profusely. The only clean thing we had to wrap his finger in was a bunch of MRE napkins. Someone had the bright idea to have him hold his hand above his head to reduce the pressure and also the cool breeze from not having a cover on the truck would keep his hand cold. As soon as we got to the range we took this kid over to the medics and they stared in baffled confusion at how the hell that happened. Good news! This kid did not break his finger. Bad news. He dislocated his ring finger, partially degloved, and tore most of the musculature that holds the finger on. The actual doctor said the only thing holding his finger on was a little bit of skin and some vasculature. Of course we are all dicks and laughed at him at the time, now years past it he laughs at it too. Fortunately the finger was salvageable, and he wears a rubber ring now. Every now and then somebody notices the wicked scar on his finger. And so the story starts with how did that happen, and ends with how TF did that happen? In all seriousness though. I'm sorry that nobody took your finger getting ripped off seriously. You're supposed to take care of your Joe's, that's a failure of leadership right there.

[@kengifford8140]

Interesting. I had always heard the 800mg was for a week after that you risk damage to your organs.

[@SuperDocRIVERS]

Who Dafuq told u that!? That person needs to be removed from practicing medicine. No medicine is prescribed or sold without advised limits. The body doesnt "filter it out", just keeps absorbing until damage is done...then filters out. Plus ibuprofen isn't recommended in the military in operational environments due to it's affects on blood coagulation.

[@blissfulmountain]

I bought a jar of 100 ibuprofen tablets because I was going to travel abroad for 5 months and I didn’t want to have to find out how to get painkillers in a foreign country where I’m not fluent in the language. That being said, it’s been 6 months, I’m back in the US, and I still have a lot of tablets left. It’s crazy that someone was able to take 10 times the amount of tablets I bought in such little time.

[@svampebob007]

google translate is your friend. I mean obviously not when you are dying or really sick, but generally you can get a lot done with a few basic google translates, and memorizing a few key phrases like: hurt, help, Head Shoulders Knees & Toes, Knees & Toes (not kidding). I've been to a lot of different countries where I had internet and using google translate I only looked like a 90 year old trying to figure out how to remember my words, but we got there eventually. And I've helped a lot of different people in my own country that though it would be like speaking to a brick wall because they didn't know the language, until I pulled out google translate. When we go offline I usually take care to learn the local "hurt, help, body parts, look, yes, no, this, repeat, thanks"

[@daviddavidson2357]

@@svampebob007 Or, just learn the names of standard medications since they're the same worldwide with a few exceptions in the US such as meperdine instead of pethidine (though you won't get that OTC unless you go somewhere really sketchy) and acetaminophen instead of paracetamol.

[@chickenlover657]

I'm always amazed hearing how eager westerners are to pop pills. In my country the average intake of medication is 40 tablets of 500mg aspirin per year per average citizen.

[@daviddavidson2357]

@@chickenlover657 You medicate with vodka instead.

[@chickenlover657]

@@daviddavidson2357 Vodka is the most disgusting drink ever invented, so nope.

[@johnyboy2338]

He descubierto recientemente este canal y ahora no dejo de ver sus vídeos. Su contenido es muy entretenido y educativo. I have recently discovered this channel and I find myself constantly watching their videos. The content is both entertaining and informative.

[@hoppytoad79]

As a teen and in my early 20s, I was prescribed naproxin sodium (Aleve) for period cramps by my doctor. The daily maximum was, IIRC, 1100mg. My cramps were so bad at the beginning of my period I needed to take the whole 1100mg iin the morning just to be able to get out the door for school, and then I'd need to take more several hours later, and then more several hours after that. That went on for 3-5 days/month until I was 22, when I was telling a friend about how bad my cramps were and how I managed them, and she said to me, "You're going to fry your liver and kidneys. You need to go see a gynocologist". I did get myself to a gyno, and I was diagnosed with Polycystic Ovary Syndrome (PCOS). The gyno put me on birth controls, and once those brought my extremely out-of-whack hormones under control, my hellacious cramps vanished.

[@_kalia]

Women: My periods make me want to die. Doctors: Sounds normal, have some painkillers The number of people I knew who've waited _years_ for their gyno issues to be properly diagnosed (and had to fight every step of the way) is horrifying.

[@jauume]

@@_kalia real! I dont understand why so many doctors think severe menstrual pain is normal, its not at all...

[@laurahuston2187]

That's a naproxen overdose. In animals, there is a very narrow margin of safety with that one!

[@lunesta5892]

Have you always had these symptoms or did they only start around 20ish? Are they better now?

[@rissahere]

……. Naproxen for cramps?! Like obviously there’s a deeper problem…. So sorry you weren’t taken seriously. I was given naproxen for my RA but to supplement my other meds if I need it. We really gotta do better in treating women cuz a bottle of naproxen is not ok.

[@CarthagoMike]

You know you are in for a ride when over-the-counter medicine and kidneys are in the same sentence.

[@BuceGar]

I don't think I could eat 1,000 Skittles without getting sick.

[@dlevi67]

Or liver... (try paracetamol/acetaminophen for measure. Actually, don't)

[@ERuleAmirul]

Ibuprofen is OTC meds in your local pharmacy? Here we have to store it inside the glass shelf and ask whether they and complications/taken any other NSAIDs before we sell it to them

[@Reth_Hard]

If it was dangerous they wouldn't sell it over-the-counter, right? 🤣

[@joewell6435]

@@ERuleAmirul I recently bought a 1000 pack from Walmart, not locked up. They didn't have Acetemedaphin locked up either.

[@DrMuFFinMan]

I'm amazed at some of the things these grown adults do. I'm not sure how anyone could have a thought process that allows them to take so many Ibuprofens in one day let alone a month.

[@xXESproductionsXx]

I can't speak to that, but when I has sciatica a couple of years ago, I took the max dose of ibuprofen that I was told on the bottle for months. It ended up giving me stomach ulcers. In hindsight, ibuprofen barely did anything for my pain, but when you're in bad enough pain, you'd be surprised what you would do just for the chance that it'll help reduce your pain.

[@mikoto7693]

I took a mixture of ibuprofen and codeine, at therapeutic doses for the vast majority of it. Occasionally I would take three instead of three when the pain was especially bad but it was occasional. It still caused two stomach ulcers that bled in my stomach for months and gave me severe anemia. The most likely cause was the ibuprofen from the mixed tablets. Thankfully I didn’t damage my kidneys though.

[@erikjan3656]

They have been to long close to a running car with leaded fuel…

[@averthewin1689]

At one point I was in so much pain due to a highschool injury, I'm 20 at the time I was taking up to 36 675mg acetaminophen arthritis meds and god it wreaked hell and back on my kidneys but no severe damage I just pee a little blood if I take any acetaminophen

[@hni7458]

@@xXESproductionsXx 40 pills a day?

[@yosh1to]

I’ll never understand why someone would think not following directions and consulting a doctors before trying something stupid would be OK

[@minipoule9824]

ER nurse here. Listenned to this while going to work, screamed at my phone to STOP the whole time. Hell to the NO

[@pleaseenteraname.5857]

That’s how I feel watching every chubbyemu video 🤣

[@thatsickkidjaz1749]

I'm not a medical professional but as soon as I heard that he thought he needed to take the whole bottle to "finish the course" as if it was antibiotics, I knew it wasn't going to be good.

[@Wildernessba]

Video too long an exhausting. Could be told in quarter of time used.

[@hugegamer5988]

@@thatsickkidjaz1749 I was camping once when I woke to a bear nibbling on my toes. I thought why not just let it finish the course. Well, I’m actually typing this from the afterlife…

[@dualcrocadile]

@ Mini Poule thank you for your service! Frontline workers are superheros 🖤🖤🖤

[@nancyjackson8886]

I was just in the ER with my brother who had a fall. When they asked him what medicines he took for some reason he told them he had taken 12 ibuprofen. The nurses and doctors went crazy getting additional blood and urine tests. My bro did not actually take 12 ibuprofen he was just confused but they were very concerned. No medication is benign if you take it wrong.

[@etherraichu]

and sometimes, even if you take it right it still goes wrong.

[@MrCoffis]

This applies to things that aren’t even medication, like water.

[@felixlara2945]

I used to do that like twice a week for a few months while I was wrestling through a back sprain a neck sprain an ankle sprain and a torn rotator cuff, was that like a bad thing lol

[@amiralozse1781]

actually, nothing, and I mean NOTHING is benign if overdosed!! did you know you can die from drinking too much water, ordinary tap or bottled water? watch "A Mom Drank 3 Gallons Water In 2 Hours. This is What Happened to Her Brain"

[@Refertech101]

depending on the dose size that is a fatal amount, will kill the liver.

[@carissawu1162]

I remember when I first started taking Midol for my period pain, I was nervous about using pain medication regularly for the first time that I would take only one tablet every 8 hours...and then this guy takes 1176 tablets in a month

[@MegidolErin]

Not really on topic but truly bless Midol. Would not survive periods without it and a heating pad

[@samueljaworski5737]

Those are rookie numbers!

[@quartzmerlin]

I genuinely don't know how people do it. I am so nervous about taking painkillers that when I fractured my leg, I only took 3 total in the entire month span I had pain, not because I was strong or hardy but because "What if I build up a tolerance and and and then I can't handle pain anymore and and my kidneys 😭😭" Now I find out military takes them like candy.

[@evilturkey523]

literally me. when taking any medication i read the label like 20 times to make sure im not accidentally taking even 1 too many so i have genuinely no idea how ppl like this take over 1000

[@realtsarbomba]

I'd recommend Naproxen and Ketoprofen over paracetamol because of liver toxicity and for both being way more potent than ibuprofen or other OTC NSAID painkillers.

[@lupusgirl64]

As a non American, the concept of a 1000 tablet pack of ibuprofen is INSANE

[@Zzz-b8y]

It's pretty cheap atleast

[@Iwillpeerintotheeyesofyoursoul]

I get anxiety from just taking one tablet, even if it’s at a low dosage. And this man has no issue taking way over the recommended amount.

[@BruceKarrde]

Same! I always consider the kidneys with ibuprofen! If the pain doesn't end in 1 or 2 days, I call the doctor - not swallow 500 more pills

[@nodevoutt]

Ikr my parents were convinced I'd turn into a drug addict if I took any painkillers and I still think so

[@MCR123321]

I'm the same way. Absolute last resort. If you ever get a sinus based headache, ginger + water is a great all natural alternative.

[@PurpleAmharicCoffee]

I'm petrified of taking more than the limit of 8 per day. Stomach ulcers sound like Hell.

[@cryptidproductions3160]

Right? When I take OTC painkillers because my back is out or something I keep track of time and dose like I'm running a scientific experiment and do my best not to exceed half the instructed "safe" dose for 24 hours This dude was popping pills like candy

[@rogofos]

after binging a lot of your videos I find it vaguely reassuring how many people recover in them even after some pretty serious things just goes to show how resilient human body is and how effective modern medicine had become

[@lebby1688]

Except for the heartbreaking case of the man who took a sip of bad coconut water, immediately spit it out, and rinsed his mouth but still died.

[@playingwithdimethylcadmium2766]

​@@lebby1688Yeah, that wasn't even his fault, the world really is unfair.

[@escthedark3709]

It kinda was his fault. It said the raw fruit had been sitting exposed and unrefrigerated for weeks on the counter, but had been refrigerated at the store. Doesn't mean he deserved to die from it, but raw, typically refrigerated anything shouldn't be consumed willy nilly.

[@E3ECO]

Yes, I'm amazed some of these things aren't terminal.

[@Xander1Sheridan]

@@lebby1688 how about don't let things that must be refrigerated sit out on your counter for a month? That's totally insane.

[@lafcursiax]

Thanks for this educational and cautionary video! "OTC medicine can still be dangerous when misused" is a lesson I wish I had taken to heart in my 20s, though not regarding painkillers, and thankfully not endangering me so much as SB. Instead of seeing an allergist, I relieved my stuffy nose with topical decongestant nose spray, ignoring the caution to discontinue after 3 days. I found I had to take it more and more often just to be able to breathe through my nose, and soon was up to once every three hours (which interrupted my sleep). Little did I know that the ridges inside my sinuses had swelled up like grapes! After finally seeking professional help, it took two courses of prednisone and two surgeries on my sinuses before I could kick the habit and breathe normally. Just because you can get something without a prescription doesn't mean you can be careless with it!

[@s0rr0wHacker]

Your comment made me realize I need help asap. Thanks for the heads up

[@Kirmeins]

@@s0rr0wHacker Good luck and speedy recovery! :)

[@rnelody5496]

I used to work at a drug store, and we had to warn everyone who bought our OTC decongestant nasal spray to never use it more than 7 days in a row. SO many people shrugged off that warning. One lady even told me she'd been using it for 3 months already. The baby nasal spray is fine to use for longer periods since it's basically just saline, but you have to be careful with sprays containing decongestants like xylometazoline, because those can have lasting effects if overused.

[@s0rr0wHacker]

@@Kirmeins thanks

[@chelscara]

My mom has to cycle through nasal sprays to stay clear during the different seasons since theylll lose effectiveness after a little while. Medicine is weird and our bodies are weirder.

[@OtakuBK]

9:06 A man of culture, I see

[@Ajvella31]

Who was that, that flashed on screen?

[@villalbaaugusto]

@@Ajvella31 He's Gabe Logan Newell, co founder of valve (company that created Steam, cs and Half Life) Hes a legend XD. But I have no idea why he put him in the video where its not related at all lol probably an easter egg

[@ricoswagger7076]

He put it right after saying the word half life, that being the creator of the game half life. Lol

[@villalbaaugusto]

@@ricoswagger7076 oooh right! that makes sense LOL

[@cardboardgod]

Such a random moment. Had to pause the id at x0.25 speed to see I it was a glitch.

[@sketchyskies8531]

I honestly thought that was a typo at first There’s no way this guy’s gonna make a full recovery Well, he made *a* recovery, probably just not a full one

[@Underground.Rabbit]

Hasn't started the video yet. Bro most likely need a dialysis and get on a donor list.

[@Jrock420blam]

yeah he's a walking time bomb now, those kidneys aren't gonna work much longer

[@n1msu]

He will make a recovery, unless you have some detailed explanation on how Ibuprofen destroys kidneys in the exact way paracetamol will destroy the liver.

[@IAmDainbramaged]

@@n1msu NSAIDs are known nephrotoxins, you can google it very easily. This guy was a moron (or the situation was edited to avoid giving people ideas) but it's more common to see opiate addicts taking tonnes of ibuprofen+ codeine tablets EDIT: and chubbyemu goes into it in the video

[@xponen]

@@n1msu shown at 8:23, it reduces blood flow to kidney, by reducing the hormone prostaglandins.

[@poliknoy]

This video literally answered all of my problems. Over the last few months I’ve been taking ibuprofen everyday (usually multiple times a day) and I’ve had sooo many symptoms that are obviously indicative of a stomach ulcer. I’m going to the doctors this week to hopefully get this sorted out 👏

[@rebeccatrishel]

Good luck!

[@vacafuega]

I hope they help you!

[@archangelgaming8077]

Ibuprofen is bad for stomach tylenol is better but ibuprofen is ment to be used rarely

[@shinjite06]

People really out here treating drugs like vitamins.

[@DerRabenbarde]

@@shinjite06 Vitamins can also damage your kidneys... There are quite a couple of videos on that on this very channel!

[@ryanmaris1917]

As a child when I was felling sick my parents would always read out the dosage and that’s what we would follow till I was feeling better. It really instilled in me the importance of following directions before the on the package and from your doctor.

[@missbearlockholmes]

That's a simple, effective way to educate a child. Nice!

[@ColocasiaCorm]

And?

[@bigbird4481]

@@ColocasiaCorm that's it, he's saying that his parents did something very simple to educate him on the usage of medicine. Now in the story in the video the man had no common sense

[@canislupus4655]

This made me chuckle a bit thinking back on my parents. I don’t remember them reading the dosage out loud, though they would tell me “okay we’re going to take this much now and then in x hours we’ll take some more” or whatever. But I do remember them picking up the medicine, looking at the back to check the directions for my age, realizing they couldn’t read the tiny font, and then having to look around for their reading glasses before finally being able to read the directions 😂 So in a roundabout way they taught me to always read the directions.

[@emeraldfire8168]

My dad did this in the 90s. Tylenol turned his blood to poison. He refused to take pain meds because he said he saw crazy stuff, so he took tons of Tylenol. I found out years later my stepmother sued Tylenol and won big money, but by then, she had nothing to do with my brother and I. She and my stepbrothers are living high on the hog from my father's death. May God have mercy on them.

[@LUImusic856]

That’s Fd up bro I hope justice prevails if not in this life than the next 😌

[@Handles_AreStupid]

It's crazy that Ibuprofen comes in 500-1000 piece bottles in the US. Here in England, the most I've ever seen is a pack was 48, but those were 500mg not 200mg.

[@Younce_Davies]

They come in small to large packs. They last a while so a 1000 pack should last you a few years. Some of us don't need that high of a dose so we use 200 mg. I had to get a prescription to get 600 mg tablets

[@Kahless_the_Unforgettable]

If people would just follow the instructions, there would be no problem with a 1000 piece bottle. This guy took 1400mg at a time, often after taking 1400mg just a while ago!!! That's WAY beyond what the instructions say. Just follow the directions. Personal responsibility.

[@Younce_Davies]

@@Kahless_the_Unforgettable So many people think over the counter = safe. That is not true.

[@Kahless_the_Unforgettable]

@@Younce_Davies , Exactly. Which is why people need to read the directions. Some OTC Drugs say that if you're taking it for more than ten days, you need to go talk to a doctor. Over the counter drugs are perfectly safe. As long as you follow the directions. If you decide to triple the dose for a month while ignoring every instruction, it's not safe.

[@oliviac3077]

@@Kahless_the_Unforgettable the reason ibuprofen & similar over the counter drugs come in small piece bottles in the uk (and the fact that you cant buy more than 2 packs) is to make it harder for people who want to overdose

[@danielz7161]

This is why my mother who is a nurse always tells me to take ibuprofen with food. Also I appreciated the flash of Gabe for a frame at 9:06 when you said half-life.

[@__________vee__________]

Thank you for this comment. I was going crazy trying to play/pause to get that frame.

[@realShadowKat]

Whew I was hoping someone else saw that!

[@liamthompson9342]

Who is that dude? I managed to freeze it.

[@inuhundchien6041]

@Liam Thompson person who made Half Life, a popular game.

[@kahlanmarcus]

Even slowing it down to .25 speed it was so hard to pause on the actual picture

[@ezrea9313]

I have had esophagitis from NSAIDs before, caused by the pills getting stuck in my esophagus. That is one of the most uncomfortable things I have ever experienced. It was painful, though not unbearably so except for when I ate/drank. Every single sip and bite of food felt like I was being stabbed as it went down, and nothing could help. I also felt like there was something stuck in my esophagus so I kept instinctively reaching for food and drinks to wash it down, which only made it hurt. Now I'm careful to drink more than enough water whenever I take a pill. Dry swallowing isn't just a cool party trick folks. It can cause real problems

[@augustoof13]

Thanks for this info. Sometimes I don’t take enough water when I take my meds, so this’ll get me to drink more

[@itsdokko2990]

yep, i should really drink a full glass of water from now on when i take my melatonin capsules. besides, water is good for you

[@dochudson9912]

i got esophagitis from a different drug, and it was because i made too many failed swallow attempts. All the water and salivary enzymes starting dissolving the capsule, and as the capsule finally went down, the drug irritated the lining of my esophagus, giving me pain when swallowing for a week.

[@terskataneli6457]

I got esophagitis from drinking half a liter of booze like a dumbass. The pain when swallowing milk or carbohydrated stuff truly gets your head dizzy

[@ultimaxkom8728]

*For you readers who will take any oral medicine:* drink a glass of water *_before_* and after, try to be relaxed when swallowing, and have someone nearby in case of choking.

[@ryanhegseth8720]

I really like the topics this guy decides to talk about, they are quite interesting and usually things I had wondered about.

[@Halli50]

Where I live, one 400mg ibuprofen every 8 hours is considered a "safe" maximum. My doctor advised a 7-day course of this - and it permanently cleared up a back pain that had bothered me for over a year. More is NOT always better!

[@vasnormandy]

Here, where I live, the safe max is 600mg

[@nicholasdean3467]

Really? After wisdom teeth removal the orthodontist had me take 400mg every two hours. That was only for 5 days though.

[@Ironbattlemace]

We have 800mg tablets that you can take 3 times a day.

[@mormornie]

hey same hat about the dosage and timing recommendations here! I was terrified when I saw the 6-a-time tablets were 200mg!

[@kiisseli1337]

@@nicholasdean3467 All my 4 wisdom teeth were taken at the same time + 6 other teeth, 2 of had to be digged deep from bone. And I took 200mg 2 times per day for a week :D Maybe 2x that in the first and second day.

[@maluinthe90s]

I just gotta say, the terminology I learned from these videos helped me through nursing school, and the breakdown of the mechanism of action of drugs into simple and palatable terms helps me communicate and educate my patients more effectively. Thank you.

[@Idkwholmao]

-emia, meaning presence in blood.

[@ck_lowman]

I've been dealing with a back injury, and it's been hard to get any pain relief. I was taking 3000mg plus a day and fighting heartburn because the Dr's didn't take me seriously after 2 ct scans and two hospital trips. My Dr finally ordered an MRI and saw that I had two herniated disks. Always advocate for yourselves people. And take care of your backs.

[@GamerLoggos]

I have the same issue. For a long time I was ignored and nothing was done for my back. Eventually I was given MRIs and found I have herniated disks, which have now basically gone totally bad. And a narrowing in the C3-C4 thats pinching my spinal cord. But I am forced to go to a pain specialist to get my meds, pee in a cup and jump through hoops. And now my pain clinic closed suddenly with no warning, and all the other clinics within a reasonable distance will not treat with opioids, only physical therapy which will not help herniated disks only make it worse, or steroid injections which have never worked on me. So I was left to go cold turkey from opioids that I have taken for years taking my dose as directed and never failed a test all because doctors will not prescribe meds I need without passing the responsibility to someone else. And now I get no assistance at all. Cant walk around or do anything more strenuous than go to the bathroom, cook or get the mail.

[@brockmitchell3989]

I did the same thing in the 1990s while in the Navy due to severe pain from an injury that the doctors would not take seriously. I told the doctor that I had taken 3,200 mg of ibuprofen, and he informed me that if I had taken one more pill, it would have killed me probably. I also did a lot of damage to my stomach, which ate away at my stomach. To this day, I can no longer use NSAIDS of any kind, otherwise I vomit blood.

[@quin2203]

@@brockmitchell3989 Many here will probably ignore this advice, but shouldn't. I knew someone who unfortunately died due to this. As described in the video, the problem can turn catastrophic very quickly because it affects both the stomach and kidneys at the same time. Just like in the video, when abused, the ibuprofen acted like land mines throughout the GI tract. If not treated quickly it then turns into sepsis and multiple organ failure. In the case of the person I knew, the hospital did not react quickly enough, assuming they were just intoxicated at first.

[@GastNdorf]

Ahah, I have had the same thing, I got an MRI right away to identify the issue but still never really got taken seriously, in the first few weeks/months my arm was litteraly shaking constantly because of the pain and everytime I touched something with my left hand (and I'm a leftie) it felt like I had needles at the tip of my fingers... But specialists pretty much shrugged because they said it was too risky to operate (right in the bulb of nerves between the neck and shoulder blades), so I had to take a combo of medisol (through injections) and prednisolone (stuff you have to be super careful about the dosis to the point you have to calculate it according to your weight because it can alter blood pressure), wear a straightening shirt, be super careful about my posture constantly... I was supposed to see a chiropractor but none was available in my area, so instead I'd just go to regular masseuse and explain them my issue so they would just get me some relaxation and relief in the area... Eventually the pain kinda dulled out but it's not rare that I wake up with a huge backpain if I didn't sleep correctly

[@kellywinsor5051]

If you need long term help, go to a pain management doctor. They will help you when no one else will. Other doctors are scared to death to prescribe pain medicines.

[@ThreeForDays]

This is a year ago but my army VA nurse recommended I take 4 200 of ibuprofen day and night because of my chronic back conditions I gained from the military. I am not listening to his advice. Even if that’s still a normal dose, that amount taken daily is not healthy and I don’t believe it’s right. That much is just terrible feeling

[@motionless_horizon]

A few years ago, I OD’d on a mix of ibuprofen and aspirin. I was in the absolute darkest time in my life and I just wanted to be done. It was a very high dose of both. It was the most hellish experience I’ve ever been through, and I’ve had heart surgery twice. I legitimately had never been so sick, scared, and in so much pain. I went from wanting to die, to regretting it and realizing I want to live, to wishing I would just die already simply so I didn’t have to feel as sick as I did. I can’t take either one now because the smell of aspirin makes me vomit, and my kidneys were damaged by the ibuprofen, which sucks because I have a chronic pain condition. So yeah, long story short; don’t OD kids, it’s not a good experience in any way

[@Karolina-e9x]

I did same thing when I was 14 and I couldn't take no pills for about few years because I could smell it and it made me gag. So I do agree. Don't ever OD, people

[@shellshockedbros4458]

​@Briansan101 Fucking stop, dude. The science behind weed isn't remotely understood enough for it to be given as a cure-all. Why you people want to make everyone in society an addict is beyond me.

[@VisibletoanyoneonYoutubes]

My od experience was great I had a newfound appreciation for life after realizing I wanted to incarnate here 😊❤infinite love But yeah, don’t od

[@twelvelyes]

Have you tried opiates🤫

[@TaylorToman]

​@Briansan101 this is deeply insensitive

[@vice979]

I remember taking 20,000mg of Advil years ago to try to end my life. Luckily my grandmother was there and was able to get me an ambulance to the emergency room. Ended up having my stomach pumped and was sent to the psych ward. I just remember the first week being there constantly asking for stomach medicine for the immense nausea and pain. It took a long time for my stomach to heal. I'm kind of traumatized from that experience and I can't even take Advil anymore. I'm in a much better place and state of mind now and glad things didn't end at that point.

[@veracityhunter7777]

Glad you didn't kill yourself.

[@WinryGames]

I’m so glad you’re doing better now

[@alexia3552]

I'm glad things are going better for you now!

[@RebeccaLynnMusic]

I'm so sorry. I'm glad you're alive.

[@bhartis3679]

Glad that you are doing fine. Take care

[@argoth83]

This is one of those situations where I knew very well NOT to do this, but it's always very interesting finding out precisely why. Having no medical background, my understanding of the actual mechanisms behind such problems is minimal, and you do a great job of explaining all of this in terms we can all understand.

[@Thobeian]

I found out because a girl kept taking ibuprofen pills out of a sandwich bag during marching band practice. She may have had period cramps or something, I never found out, but she just kept taking a handful every hour or so to counteract it, and ended up sick and unable to practice for the rest of the day. She was known for not being the smartest, but I can only imagine that she either got them from her parents who didn’t tell her, or she disregarded the drug use facts because she was 15 and didn’t know better. A lot of people where I’m from are leery of “drugs” given by a doctor, since it is somehow a form of dependence. Unless it’s otc, and then you can just give a pill to anybody who says they have a cough. It’s the same logic that the person in the video outlines: “it’s otc, which means it’s basically candy”

[@JesusElYisus-wq9kl]

Vivo en Venezuela y yo lamentablemente debo tomar dos diclofenac al día por un dolor molar.. ya que no tengo el dinero para sacármela.. se que me hace daño pero me toca mientras reúno los 30dolares para la extracción.. espero no enfermarme.. ahora este video me despertó el miedo 😢

[@zachross3541]

I remember baseball season. I would throw 100-200 pitches daily and after a month each throw was in excruciating pain. I started with 2 ibuprofen, then found that 4 felt better, why not 8? For a month I would take 8 ibuprofen daily to cope with the pain of being overused. We called them skittles or arm candy. There are other players out there right now doing this. I know because I was not alone and I still hear stories of people taking 10 ibuprofen and an energy drink to feel “good”

[@noxscotchxtape]

Good way to totally ruin your shoulder and for what a game. That said if i was paid millions I'd do it too.

[@neoanderz]

@@noxscotchxtape millions is nothing when you have to pay for American healthcare lol

[@idunnobouthat7092]

How's your arm now? Did you ever end up getting Tommy John surgery?

[@Squilliam-Fancyson]

Yeah ibuprofen is a huge problem in professional sports nowadays. Everything above 1000mg ibuprofen a day is very unhealty over time, especially for the liver and kidneys.

[@porcelainchips6061]

I was in a situation where my primary care doctor kept encouraging me to take Ibuprofen "as often as you need to" for chronic pain and to take it in combination with my codeine 3 prescription whenever I took that. He was insistent on the idea that eventually all I needed to be on was Ibuprofen daily. Then, one day I was being examined at the pain clinic by the doctor who manages my migraines and spine injury and he was worried at how swollen my legs were and that I had recently developed heart burn. We talked about the dosage of Ibuprofen I was taking and how I had ended up taking at least 200mg daily. He told me to just stop that cold turkey and only a few weeks later the swelling and heart burn was gone. My primary care doctor said these things were unrelated, even though stopping the medicine co-insided with the negative symptoms disappearing. He retired shortly there after, but I believe this was an example of a doctor handwaving the potential seriousness of over-the-counter medications.

[@aliveandwellinisrael2507]

"At least 200mg daily" So.. around one tablet per day?

[@gateauxq4604]

If he retired he was probably old. Ive seen too many old doctors who ended up having last looked at medical journals in the 70s. Thank god most of them are not practicing anymore.

[@gamingfiredrago]

Thanks for sharing your experience. Hope that old doc gets sued for giving unnecessary and potentially dangerous prescriptions. Also, I'd like to say that swollen legs/feet are generally due to issue with our kidneys (fluid retention). I hope your kidneys are not adversely affected by those meds, please take care.

[@batbebebe]

200mg isnt bad at all lmao. thats about 6000mg a month. some people take 200mg near daily for migraines. did you ever get your liver checked for prior liver damage before taking ibuprofen?

[@lemmypop1300]

@@aliveandwellinisrael2507 Probably 2000, I guess it was just a typo.

[@liserjones8465]

It's astounding that so many people either think a few painkillers will harm you and then the opposite that they can take as many as they want! In the UK we have an issue with a medicated drink called Lemsip. It tastes like hot lemon but has paracetamol in it and I constantly hear of stories where people get a cold, drink lemsip AND take a dose of paracetamol. It only takes 15 to cause irreparable damage & death.

[@Farimira]

I love lemsip, its great for when your throught is too sore to swallow pills. But there needs to be better warnings/education for medicine like that

[@TheBrothergreen]

15 what? 15 cups of theraflu? (the US version of lemsip)

[@xXDESTINYMBXx]

Thes flue relief medicines are a bit dangerous because people often don't check the ingredients and think it won't be the same as e.g. paracetamol.

[@bakachan3601]

Not know what's in the medicine you're taking, and thinking it's a different drug based on brand name is willfull ignorance.

[@jasminel8166]

my parents always made sure i knew there was paracetamol in lemsip for this reason and were like make sure u spread them out

[@justaperson4065]

I developed a sudden and extreme allergy to Ibuprofen. I had a bad back ache, and took some. A few hours later, I was in the ER getting 4 blood transfusions. I had bleeding ulcers all over in my stomach. But the doctors told me they were caused by stress because I was renovating my business's building. I was confused because I didn't feel overly stressed, but I trusted my doctors and tried to add meditation to my daily routine. A few months later, I had a terrible headache. I had always wondered if the Ibuprofen had actually been the cause, but my doctor had told me that wasn't the issue. So I took just half a dose of Ibuprofen, and ended up in the ER again. Bleeding ulcers. So, Ibuprofen scares me.

[@isthiscereallife]

Something sad to be said about NSAID misuse is how common it is among the chronically ill. Typically chronic pain or aches will be brushed off as the patient being opiate-seeking. Or the doctor will tell the patient to just take NSAIDS. And when NSAIDS aren't enough, the patients will up their dosages to try and make sure they can at least function during the day... which leads to GI and kidney issues. Sometimes the doctors will treat the GI issues instead of the necessity for higher-strength pain medication.

[@XSemperIdem5]

This is so important to point out. So many people with chronic pain aren't getting the treatment they need because doctors went to the opposite extreme of accusing everyone who needs opioids as drug seeking. Chronic pain is horrible to live with and so debilitating.

[@isthiscereallife]

@@XSemperIdem5 Yeah... unfortunately I've seen it happen to friends; I don't want to get peptic ulcers or other organ damage so I end up foregoing using the only pain meds I have and just coping with it. 😓 Unfortunately if you don't use a lot of NSAIDS to cope with it doctors will also think you're faking, especially if you're young. It's a lose/lose situation.

[@DespicableMe24]

I am a doctor we just can't give anyone opiods even if we give it will build up tolerance in pain but no tolerance in side effects like respiratory depression so is it okay if you wanna die a less painful death by an over dose of opiods ?

[@isthiscereallife]

@@DespicableMe24 What are you talking about? I'm talking about doctors brushing off disability and chronic pain because they _think_ those with chronic pain are opiate-seeking, thus leading to NSAID-caused organ malfunction and failure because of said inattention. Are there not pain relief drugs besides opiates and NSAIDs?

[@DespicableMe24]

@isthiscereallife I don't know which country you are talking about but yes it is our job to tell each and every patient about every possible side effects and possible hazards of drug overdose. This is routine practice to me. Yes some of my colleagues are negligent about it and yes that is wrong. As far as the idea that doctors consider people like these opiods seekers, you are right but there is a history to it I once abused stimulants to treat my depression and anxiety when in reality I should have gone with what I was prescribed by psychiatrist. And yes I did recovered when I followed the psychiatrist. And would say that there is a great amount of truth to what you said some times people are just diagnosed as malingerers when in fact doctors should be more patient and less judgemental. Last part unfortunately we don't have much alternatives to steroids nsaids and opiods some do exist but they are for very specific types of pains.

[@rkem139]

When I became a kidney donor, the donor team put the fear of NSAIDs into me. This story is particularly terrifying. While that case was one of ridiculous disregard for directions on use, I guess one thing is that most people don't realize that prolonged use of NSAIDs can be bad for your kidneys.

[@krashd]

How many kidneys have you donated?

[@sockswastakentwice]

@@krashd 7

[@BtheLee11]

The more common types of NSAID poisoning i see as an ICU RN are when people take an Advil, then they'll take some motrin, and then maybe some ibuprofen. But hey guess what, those are all the same(ish) drug just under different trade/generic names. If you want to avoid this, always check for the generic name on the bottle (it'll usually be right underneath the trade name in smaller text, if it's a generic it'll just have the name there in print so you know it's generic) and check the active medications on the label! Another common poisoning i see is tylenol poisoning especially now that drinking nyquil is a thing. There's a full 650mg of tylenol in nyquil in a liquid form. It's so easy to overdose on tylenol in liquid form.

[@faridb40]

@@sockswastakentwice like what kinda question is that 😂

[@bradleywhais7779]

And acetaminophen bad for the liver

[@8stormy5]

My mom has a friend who'd refuse to take ibuprofen with food, stating she "always had an iron gut". She took some for a few days in a row after pulling a muscle- an ulcer burst in her stomach and very nearly killed her. PLEASE follow the directions on all medicines, no matter how minor! I also attempted to abuse acetaminophen and ibuprofen when I was a stupid kid. I didn't have a GI bleed, but I did suffer permanent hearing loss.

[@alexia3552]

I did not even know that it could do that, I'm sitting here watching a chubbyemu video and it still didn't sink in how much the body is connected

[@jonescrusher1]

Did you abuse those drugs as a suicide attempt or to get high?

[@max-gi1vw]

wait you’re supposed to take ibuprofen with FOOD?? I never knew that!! I’m only 13, so I haven’t used much ibuprofen, but I’m glad I learned that

[@naverilllang]

@@max-gi1vw i don't. But I've also never taken the maximum dose for days in a row. a little rule of mine to never take the maximum dose of a medicine.

[@billgatesisntadr7995]

Taking it with food may help with occasional use, but like he said in the video, ibuprofen effects prostaglandins which play a role in regulating stomach lining so long term use can cause ulcers even at the right dosage.

[@TheExilarius]

This was a insanely good Pharmacology class. Loved it

[@supernus8684]

It always amazes me the decisions grown people are capable of making. Like how can you have gone through life without ever hearing about the dangers of taking a lot of pain killers? And 1176, thats so insanely many its absurd how anyone could think this is fine.

[@raven4k998]

I took an extra large bottle of that my kidneys are fine just burned my liver out but my kidneys are fine no issue🤣🤣🤣🤣🤣

[@zealman79]

Definitely a trump voter

[@jonathancaldwell517]

He is lucky to have made it a month. I'm glad he recovered. I know the bottle says not to take more and most reasonable people wont, but I wish more people would educate their kids with these kinds of videos.

[@dovestone_]

As a Brit having them come in this giant bottles is asking for trouble, regardless of the directed use.

[@desti5857]

Would you ever do a story over postpartum cardiomyopathy? I recently had heart failure caused by pregnancy and I find my story and other's interesting because so many of us had our symptoms dismissed as panic attacks or that we were being overly dramatic about normal pregnancy symptoms like swelling and shortness of breath. I'd love to see people become more aware of this condition!

[@placeholderdoe]

Sorry that your symptoms were dismissed, I’m glad you’re better now

[@ariagrace7431]

That’s so scary and frightening and just another thing to worry about while being pregnant! Glad you’re doing ok.

[@cai3886]

Oh my god, another thing to add to the list. 🥲 So sorry you weren't taken seriously, hope you're doing better now!

[@solarrae]

i don’t think i’ve heard a postpartum story on this channel, would love to hear about one. edit bc my forgetful ass forgot to add this: it’s a damn shame those doctors didn’t take you seriously and it speaks on a bigger issue of doctors denying women treatment on the basis of “over exaggerating”.

[@pepega3344]

That doesn't fit his channel at all...

[@anonymouse265]

I remember making the mistake of taking two Ibuprofen tablets without water for a pretty bad headache. Ended up having gastritis for at least the rest of the day. Also, shout-out to SB's kidneys for staying alive that long!

[@PelemusMcSoy]

I couldn't even down one without water; too bitter!

[@midnightpurple555]

When I was a kid, I remember drinking an entire bottle in one go. Thinking back, I have no idea how it didn’t trigger any side effects

[@anonymouse265]

@@midnightpurple555 Wait, this stuff comes as a liquid as well? 💀 I'm used to getting the tablets from those plastic and aluminium grids the pharmacy sells them in.

[@oo8962]

How do you take pills without water? Even with water, I still had difficulty swallowing pills

[@anonymouse265]

@@oo8962 I just popped them in my mouth and ingested them with my saliva. At the time I didn't really care how bitter they were, I just wanted the pain gone and was too lazy to get some water. :/

[@saml7610]

Last time I had to go get emergency care, while my wife was driving me to the ER, I was writing down a bulleted list of all the things I'd consumed - drugs, food, drinks, smoking/vaping products, etc - as well as all the possible changes in my routine that could be involved, and then trying to note any changes to my environment (i.e. did I notice mold growing somewhere? Have I been driving more? That sort of thing). I handed the list to the doctor, and after examining me they said it was great to have the summary of everything I'd been doing that could have impacted my bodily function. Turned out my gallbladder needed to come out, spurred on by a new drug I'd started taking that was prescribed by a different doctor (to clarify, the drug didn't cause it, it just expedited it), and it had yet to make it into my chart at facility I normally go to, so they wouldn't have known that had I not written it down. It boggles the mind that so few people do this. I strongly recommend ALWAYS coming prepared to the doctor, that is if you have the mental faculties to do so. If you're using less than legal drugs or something similar, and you feel that you may be arriving at the doctor unconscious at some point, then it wouldn't hurt to get a little notecard and write down what you're about the inject/smoke/etc before you do it, then shove that in your shirt pocket or put it in one of those lanyards meant to hold an ID badge (doctors will be more likely to notice a lanyard with a notecard vs. a notecard in your pocket). I did this when I was using heroin (luckily no longer using) and it saved my life once. The EMT's found the notecard hanging around my neck, and immediately read out what I'd done. I was dipping in and out of consciousness for a while, but I caught snippets of their conversation, talking about how I was the most organized addict they'd ever dealt with. Wish I could buy those guys a beer or something now, they saved my life when a lot of people would have turned a blind eye... Either way, you can't always think ahead and have information ready for the docs - especially if you're showing up unresponsive - but if you can go down the list and note any abnormalities, it may just save your life. I hope y'all are staying healthy and living good lives, cheers!

[@WalkingJake]

Can u still get good shit? Lmk

[@saml7610]

@@WalkingJake lol not anymore, I made sure to move 1,500 miles away so I'd have no connects once I got clean. If you're serious, I hope you can get clean. Kratom really helped me quit cold turkey, since taking it eliminated the withdrawal symptoms.

[@apcolleen]

I'm glad you got out of that life. I hope your thoughtfulness serves you well.

[@sapphirelane1714]

Congrats on your sobriety! Also, I’m glad you had good healthcare providers who actually cared. I’ve spent a long time writing detailed lists just for the doctor to barely glance at it and give it back. I’ve never run into one who cared, so I also stopped caring.🙄

[@PerryPlatapussi]

@@WalkingJake praying for your sobriety

[@starling1226]

My psychiatrist told me she once had a patient who would take his entire weekly doses all in one day so he wouldn’t have to take it every day. No wonder why we have so many labels on everything.

[@official_Chubbyemu..]

@official_Chubbyemu ☝️write me✍Lets talk🎁🎁.

[@a_bar8579]

A very valuable, dramatic, scientific lecture ❤️

[@onbored9627]

"How does the ibuprofen know where the pain is?" has got to be the funniest line I've heard on this channel so far. Bravo.

[@pioneercynthia1]

It seems like an honest question, tho

[@NickTaylorRickPowers]

Hahaha yeah if you are 5 years old

[@exiavaganza]

@@NickTaylorRickPowers Or if you're 99 years old. Always make these questions.

[@RayPoreon]

It's hard to belive someone took medicine with the same outlook of "well I've gotta finish it", as if it was some sort of perishable food leftover from dinner, they came close to getting a darwin award. A mantra that bears repeating is that any drug, no matter how tame, is a poison in high enough doses.

[@ObscuriaDragunAed]

9:07 I Gabe this Newell timestamp because Half Life. I use Ibuprofen as my go to, and drastically reduced my intake over the years because it felt like ulcers were starting to form. Due to some malpractice and intentional mis-diagnosis by a "doctor" that, at the time, was under the employ of a VA clinic, I had to have my kidney levels checked because their intentional mis-diagnosis let a common UTI knock on the doors of sepsis because they refused to prescribe me a simple anti-biotic due to ignoring the very very apparent symptoms of UTI... went back to that "doctor" because I had to in order to get the VA to cover my prescription after the in patient stay. I hadn't seen my kidney panels, so I didn't know if they were normal or not,.. until that "doctor" decided to try and blame the fact that I almost dealt with sepsis over low kidney function due to "ibuprofen abuse"... which, then she had to STFU because my kidney panels were normal. I did, at one point, though, take a bit too much ibuprofen on the regular to help me deal with my scoliosis. This was in small part due to the fact that when I was in the Air Force, doctors were on this huge kick to recommend taking max dosage for ibuprofen to deal with pain I recall one of them telling me point blank with a smile on their face "Just up the amount of ibuprofen you're taking, you can take 1600 mg per day without any negative side effects.". Uhhh... yeah... sure... In retrospect, I know that's bollocks, but, at the time I thought "WTF ever, whatever works." and did that for years. I'm thankful that I didn't end up in the same boat as the person in this story, but, I don't believe I've ever ingested a full 1k or 2k ibuprofen pills in a single month either. Had a coworker in the Air Force, though, that wasn't so lucky. He had some sort of nasal condition that was painful and lead to constant congestion, so, his remedy was taking a huge amount of ibuprofen and sudafed. Which, well, he got deployed to some base in Europe for a year, and, the weather there was just the right mix to further agitate his condition which got him to up his intake of both ibuprofen and sudafed. He came home early because his kidney's had shut down and they couldn't aid him at our overseas bases... He made a recovery, but, that sort of made me scale back my ibuprofen intake considerably. Now, I stick with the liquid gels, and ever since I'd found out the benefits to kratom in helping with pain management, the ibuprofen intake has dropped even more drastically as kratom is safer and also doesn't lead to ulcers, so, ibuprofen just gets used for nasty headaches, etc. (just in case some read and was alarmed by the kratom thing at the end, seriously, if it were an addictive drug I'd not be bothering with it as although I don't have an addictive personality, I was an alcoholic and I'm not looking to get another addiction to replace it, and, I have stopped taking kratom for a month cold turkey with withdrawal symptoms less severe than stopping caffeine cold turkey and definitely less severe than when I kicked the bottle to the curb).

[@moonpig9035]

Was wondering who the man in glasses was that popped up

[@ObscuriaDragunAed]

@@moonpig9035Lol, me too. I'm glad my obsession regarding images that flash up mid-video until I can figure out what the image is helped answer that for you.

[@moonpig9035]

@@ObscuriaDragunAed forever grateful lol was bugging me big time

[@roringusanda2837]

If you're dead, you stop costing the govt money...that's about the size of it.

[@J-D248]

LOL! I couldn't get the frame to completely stop to be able to see it, but figured that's what it would have been. Love the little easter eggs he drops. 😆

[@LucasAlmeida-dz5xh]

This is a great lesson on why you NEVER exceed the recommended dose

[@lasagnakob9908]

When I worked as a table cleaner at a popular chain restaurant, I only took _4_ ibuprofens a _day_ when I had shifts, which was only the weekends. I've always been paranoid of the effects of drugs, so I never wanted to take them unless I had to, or in this case, lessen the soreness in my legs and feet. But 7 to 28 tablets a day? It's insane anyone would ever be crazy enough to do that, let alone taking an entire bottle in a month.

[@ammonil1261]

I feel like 4 a day might still be unhealthy, but I’m certain it won’t do near as much damage as 2 an hour every day for a month like that guy lmao

[@hirvonenm]

The strength of the pill does matter. 800mg every 8 hours is still safe, though I wouldn't recommend for long term usage. If the pills you took were 200mg like in the vid, you'd be ok to take four of them at once, every eight hours.

[@GauravKumar-tq1kw]

Even 4 tablets a day is too much. I barely eat 2-3 pills a month

[@hirvonenm]

@@GauravKumar-tq1kw Yes, well good for you for either not needing NSAIDs or getting by with minimal dosage. Not something that everyone can do. As to the "too much" bit, lets just agree to disagree. I doubt I can change your mind about it even if I cared enough to try. You do you.

[@filipfrondelius3644]

Honestly having sore feet is a underlying weakness which can be fixed by other means other than medicine

[@coinwater8511]

Thank you for clearing up the myth about becoming tolerant to ibuprofen. I avoid taking it even when I'm in real pain so I don't become tolerant to it, but now I know that is a myth. Of course I will always follow the label, but I don't have to be afraid of the medication either.

[@extropiantranshuman]

I don't take it - because I got sick like this person even when following the label - just not to where I went to the hospital.

[@seekittycat]

@@extropiantranshuman You might want to check if you have a stomach ulcer then!

[@extropiantranshuman]

@@seekittycat the stomach replaces its lining - it'd be surpsing if I still have one. However, I don't take medical advice from anyone in a youtube comment unless they ahve medical expertise.

[@Bellaa4578]

Same. I only take pain killers if I can’t take it (only during my period)

[@tylern6420]

one of the only factors that determine medicine tolerance are genes

[@biswajitnath804]

I work as a pharmacist in a govt hospital... In my last 4 years of job experience I have encountered lots of people taking these types of OTC drugs more than their prescribed limit..and suffered because of it.. They think these medicines are safe and nothing wrong gonna happen even if you take little more than what's been prescribed.... But here we are again.... Thanks for awareness 🙌🙌

[@Demagora]

I know a ton of people who know that the prescription strength is 800 mg so they take 800 mg whenever they take it at all. Like, it's just a headache, you'll be fine taking the normal OTC dose.

[@NickanM]

Here in Sweden the biggest amount of pills is 30 in a package when buying without prescription. I have prescriptions, and the maximum each time is 100 pills. The amount of overdosing has been reduced by 63%.

[@biswajitnath804]

@@Demagora lemme give you an example.... A man used to take paracetamol 650 for fever.... But one day he is unable to find paracetamol at home, he had prednisolone 20 mg lying around..he knew from somewhere corticosteroids can be used as alternative....hmm...but..20 mg seems so low in dose... Will it work?... Why not take at least 3/4 of it.... That's the logic there.... It's silly but true incident I faced.. I also met some taking amlodipine 5 mg tablet because he thought he had high bp because his head felt heavy.....

[@mycosys]

@@Demagora do they also know prescription doses need to be taken with food and stomach acid drugs to protect the stomach? Theyre the max dose safe for teh kidneys

[@scotta.5681]

I almost died from a bleeding ulcer in 2003. As a result of the blood loss I also lost 70% hearing in my left ear due to nerve damage. Now I have non-stop tinitus which is so aggravating. I remember how long I let it go before I realized what was happening to me. It was a stupid move - worried I may have colon cancer and didnt want to discuss the non-stop constipation I was having due to embarrassment. Reached a point where I could hardly walk any distance because I would be out of breath. I finally took my doctors advice and went to the ER. What an idiot I was.

[@thewugglyump8045]

I've been told by other runners not to take ibuprofen after runs because making it a habit can be so harmful. Thank you for this one, I'm glad to know more details about why it's a bad idea. Lucky for me I'm too lazy to keep running if I start hurting.

[@deadbeef576]

Pain is a signal from the body that the activity that was done did damage to the body. So just turning that off by taking drugs seems stupid to me. And something else that is stupid is pushing sports so far that this pain starts. If you are overdoing it so much/do it so wrong that you have pain afterwards, you should look into what causes it. Either your type of running has to change, or the shoes, or you simply gone too intense to fast without a time for your body to adjust.

[@BitwiseMobile]

@@deadbeef576 it depends on the type of pain. Sore aching muscles are expected and you kind of want that - it means you did some work. Acute pain that limits movement is injury. I've been riding 200km a week for over 15 years. I am acutely aware of the types of exercise pain you can experience - I've experienced the gambit ;) @thewugglyump8045 CBD is your friend. It makes a HUGE difference. You don't get high - it doesn't have the psychoactive substance that makes you high - but it definitely quiets those aching muscles after a hard workout.

[@gayusschwulius8490]

@@BitwiseMobile "Sore aching muscles are expected and you kind of want that - it means you did some work" Actually, you shouldn't get DOMS anymore after training for a while, because your muscles can adapt. If you still get it after achieving a decent level of fitness, you're overdoing stuff.

[@quincy-2000]

I was told taking ibuprofen too often can actually cause it to become antagonistic and make inflammation from running worse. Even though this seems disproven by the explanation of its function in the video, it’s still better to avoid medication for workout related inflammation unless you are planning to take a few days off to heal instead of using it as a quick fix.

[@mjkittredge]

@@deadbeef576 I think a lot of it is just wear and tear on the joints, tendons, ligaments, cartilage that causes the pain, especially as you get older. You can reduce it by resting plenty and switching up activities but if you lead an active lifestyle it's inevitable.

[@SomeCanine]

Yep, that part about NSAIDs in your stomach is spot on. Ibuprofen and aspirin will eat away your stomach if you take a lot of them. If you have constant pain that you need to deal with, you should get a doctor to recommend a specialist type of prescription medicine to treat it. You don't want to add internal bleeding and stomach pain to your existing pain issues. If you've been doing it, you should stop and possibly see a gastroenterologist for an upper endoscopy to check for ulcers.

[@raven4k998]

this is why the manufacturer say's the dose limit for a reason and going over that limit will cause a problem which is why they limit it for a person

[@8stormy5]

Absolutely. Those packages say "do not take for more than two weeks" for a reason!

[@raven4k998]

@@8stormy5 and this is why it will mess you up or even kill you if you take them for long enough the difference between getting enough and poisoning is simply taking more then enough

[@nickm2558]

I just ran across your videos and have to say they are very well done. I am a medical professional and this video demonstrates the importance of being able to gauge the knowledge level of patients. Sometimes I get questions that are so far removed from what I expect to be "common knowledge" for the average person that I start from the very basic questions. Like for instance, I have had people tell me they take no medications, then later they say well, today I didnt take them, but on mon/wens/friday I take warfarin. I have had people say they have never had surgeries, then find numerous long healed incisions along the spine. I question them on that, and then I hear, well I did have a fusion 10 years ago, well that is a surgery!

[@ihmsfm1040]

True! Some people have no basic knowledge of their own body sometimes.

[@unsealedhades76]

They could also have a terrible memory I do because part of my brain is smaller then normal and underdeveloped I also have over 30 medical problems so I have multiple different things affecting my whole body and let me tell you my memory is so bad I forget what I'm thinking it even happens while I'm talking I forget if I brushed my teeth I even forget what I'm thinking multiple times a day and I'm only 17 and I can't tell you what exactly is going on because I'm in the undiagnosed disease program so none of my doctors could tell me what's going on I have more experience being an adult then being a kid with all my pain everyday since I was 4 and multiple different tests I've had both of my legs broken and rotated because of both legs being deformed and now I'm probably getting knee surgery if it isn't too late because the surgeon was to scared to stick a needle in my knee to see if I have Chiara my other doctor thinks I have the type where it can only be diagnosed once they do surgery I told her I've had a spinal tap and that she was fired she was to scared to even give me 3% pain cream she said I take to much nsaids when I don't take pain medication my life is already screwed up from the beginning I'm not going to make it worse by being addicted to pain medicine sorry for rambling point is not everyone is not smart because they sometimes take more pain medicine it's just they forgot they took it already I forget multiple things everyday even when im talking to someone then there's the people who can't control how much medicine they take because they aren't in the right mindset

[@vinny-is-here]

I put your comment in a community post and I tried to ping you but KZbin wouldn't let me. I pinged Chubby Emu, too.

[@hnr9lt-pz7bn]

​@@unsealedhades76 what is Chiara? 😮

[@unsealedhades76]

@@hnr9lt-pz7bn chiari is when stuff is pushing up against the spine there's different types of chiari it is usually found during mri but some of my doctors think I might have the acult tethered cord that can only be diagnosed during spine surgery so I don't know if I have acult tethered cord or chiari because none of my doctors are working together on finding out what's wrong they just send me to get different tests and decide not to communicate with other doctors so i have to communicate with them all which is over 30 different doctors but symptoms of chiari are Pain areas: in the neck Muscular: muscle weakness, problems with coordination, stiff muscles, or overactive reflexes Sensory: pins and needles, reduced sensation of touch, or uncomfortable tingling and burning Visual: blurred vision, double vision, or sensitivity to light Also common: difficulty swallowing, headache, nausea, rapid involuntary eye movement, ringing in the ears, vertigo, or impaired voice and I have almost every one of these problems but with me it's tricky because I am in the undiagnosed disease program and I have over 30 medical problems so some of these symptoms could be caused by two or more different medical problems so the only symptom of chiari I don't have is vertigo but everything else I experience

[@justanotheryoutubechannel]

I feel so bad for this poor guy, I can’t believe he ended up in this situation. I don’t want to mock him or anything, but this is immensely foolish… finishing a course is one thing, but when it’s 500 pills!? I just feel bad that he didn’t know better and suffered for a month, nearly killing himself. It’s really incredible that he survived and partially recovered!

[@KatinkaPofmuis]

That he didn't suffer intense stomach pain, is baffling. My older sister took Ibuprofen for three weeks after falling and injuring her knee. She took the recommended dose but into the third week she started complaining of stomach ache. By the weekend she started throwing up blood and she called the ambulance herself. She died that night in hospital, alone. Medicine is a wonderful thing but it has to be taken with great care.

[@kuishin]

How much did she take on a daily basis ? And I’m sorry to hear about that.

[@jewelmathews1408]

I am sorry for your loss

[@cwill2127]

@I :V yeah has to be some underlying issue. Sorry for his loss but I’m willing to bet my life there was some underlying issue

[@snowyowl2784]

This uh... I don't think this is normal. It sounds like there was something underlying.

[@dagmar0904]

@I :V yes, for the throwing up blood and then dying. But intense stomach pain? Not so much - nsaid are known to be one of the main things that cause gastritis

[@LegendOfKitty]

I suffer from chronic migraines and took store brand excedrin and ibuprofen to help with the pain. I followed the directions on the bottle very strictly, but because my migraines are so bad and last so long, I'd take the medicine every day for sometimes weeks at a time. Now, I'm dealing with ulcer symptoms because NSAIDs can be really hard on your stomach, even if you've eaten something before taking them. I'm seeing a doctor about both problems (and finally got a referral to see a neurologist), but until my stomach problems go away, I can't take what I usually took for migraines. Long story short, I FOLLOWED THE DIRECTIONS but because I was using the medications so often, I still suffered bad side effects. And then THIS GUY takes over 1,000 pills in a MONTH?! Absolutely mind-boggling.

[@koali7841]

Can also cause rebound migraines, learned that the hard way but also got gastritis myself and I only took it 3 times a week usually.

[@Fists91]

Did the instructions on your packages not say "do not use for more than a few days" "see a doctor if symptoms persist"?

[@francisnguyen5700]

That is why my doctor prescribes Sumatriptan instead because acetaminophen just gives me too much stomachache.

[@bonniea8189]

@@francisnguyen5700 Acetaminophen? Wow. That's supposed to be the least problematic NSAID for the stomach (more of a problem for the kidneys)

[@sirflimflam]

Some years back when I was in severe pain, I remember taking a lot of ibuprofen often in conjunction with tylenol. Wasn't a thousand but I could definitely go a over the listed daily limit for a week or two at a time (not very far over but over nonetheless). It always kinda scared me when I did it because I did take the label to heart but when you're in serious pain and it actually works, it's kind of hard to argue with results. These days I don't have much of a reason to do that, but this video definitely reminded me of those days.

[@Demagora]

Taking the two together is fine, that's no problem. Should still follow the directions on dose and time though. With children they often recommend alternating between ibuprofen and tylenol. The two don't interact, and since children have much tighter limits on how much of either they should take, it spaces out the two so there's far less worry about an overdose of one or the other.

[@Jamal_Tyrone]

Lucky it worked for you, my lower back pain was never satiated by it, I needed to borrow co-codamol pills from my sisters who used them for bad periods. It never quite fixed my back pain but it relieved it enough I could get on with my day. I rate ibuprofen as one of the crappest do-nothing drugs ever invented and it was all the doctors would give me for my severe back pain, no thanks!

[@ShaddowDemon]

I used to take pretty much the max recommended dose for excedrin (tylenol + aspirin) for months at a time for migraines. And it wouldn't necessarily be spread out during the day (i.e. wake up with migraine, 3 pills and 1 an hour later if it doesn't get better, continue with 2 every 4-6 hours). I actually asked my doc to make sure my liver is ok haha (all good!). Nowadays I rarely get migraines... might have been TMJ related, since I got treatment for that (although, chewing never caused pain to increase or start, and no signs of bruxism). I've recently started taking ibuprofen for some stuff and for the much less frequent headaches... never paid attention to eating/drinking with it. Maybe now I will.

[@Bruce_Wayne35]

You can take Tylenol with ibuprofen if you need better pain control. It is safe to do so and helps you avoid taking too much of either drug.

[@Hidihidihidiho]

@@ShaddowDemon NSAIDs are like (mild) sand paper to the skin of your gi tract.

[@timbuckthe2nd642]

Congrats on 3 million!

[@ameliarose47]

The idea that someone saw a 500 pack of ibuprofen on the shelf and thought you had to finish the whole bottle like a course of prescription antibiotics is incredibly alarming.

[@Daemonarch2k6]

Like Einstein once said - the human stupidness is endless

[@FatalShotGG]

​@@Daemonarch2k6lol

[@vickiethompson9245]

Many don't finish a course of antibiotics. If they start to feel better, they save the rest for the next illness. No understanding that different illnesses require different antibiotics...

[@MandeepSharma-p1z]

IQ of 50

[@myotismyotis]

Sorry, but I don't need a medical degree to know that eating painkillers like chocolates is a horrible idea.

[@yvazquez88]

IBUPROFEN is not a painkiller- please research. It is an NSAID- Anti Inflammatory medication which can be extremely damaging to the G.I. track but NOT A PAIN KILLER.

[@JackO024]

You can't even eat chocolates at that rate. 😂

[@JacobConkin]

Just a small correction, Advil is not a painkiller, it's an analgesic Nonsteroidal anti-inflammatory drug. Painkillers are generally a type of narcotic such as opioid medications.

[@greg9069]

@@JacobConkin and pain killers by themselves aren’t toxic to organs in the body, but for some reason they mix them with NSAIDS and Tylenol to make them toxic.

[@eduardoanavarrov4840]

Hi Chubby! Thanks for the AudioTracks in Spanish and Portuguese! Is amazing that you are going all the way to have those considering that maybe those speakers are a small fraction of your community, that for sure is something that set you apart from other content creators and truly speaks wonders about your dedication and passion! Keep up the good work!!!!

[@3rdvoidmen594]

Wow, didn't even know KZbin did that!

[@EggBastion]

@@3rdvoidmen594 same! Hallelujah! Shame KZbin'll just as silently get rid of the feature in 6-18 months from now just about the same time as everyone starts to really find out about and make use of it

[@disgustof-riley8338]

Ummm sick??? /pos

[@EggBastion]

...since May 15 2021 !??!? so it's almost over already *_`;_;_*

[@spiritedaway0tutu]

I take a relatively high prescription dose of ibuprofen twice a day for my Ankylosing Spondylitis, and the amount he took is horrifying. I can’t imagine taking seven EVER, let alone multiple times a day. I’m surprised he wasn’t in so much agony that he couldn’t move or eat, given how painful it is to take it incorrectly. My dose, while it matches my body weight and struggle with medication metabolization issues, is still considered highly dangerous for long-term consumption, so we are watching my kidneys like HAWKS. This guy took so much more than me that it is insane he survived it with any kidney function left. I have those 1000 pill bottles since it’s just more convenient in the long run that having a bunch of smaller ones. The bottles very clearly state, in multiple places, that you should never exceed the dose on the bottle unless ordered and monitored by a physician.

[@prozacchiwawa]

my father was taking far too much ibuprofen for a while, complaining that his hip hurt but the pain he was having didn't seem to come from arthritis so doctors kind of ignored it. it turned out that it got better when he had gall bladder surgery. i think the moral is that people aren't always good at explaining where pain is and i think doctors were thrown off and didn't take it seriously. hoping the next person to go through that can get the right examination to figure out what's wrong without spending a long time waiting.

[@uarestrong76]

also theres a thing called reffered pain. Often for places that don't have pain sensors (most organs don't) there is a "referred" pain where the pain travels to places unrelated to the direct part. ergo why you can have back pain even though its your pelvic floor that's hurting. Or shin pain when its actually your meniscus. Learned that from a meniscus injury.

[@etherraichu]

@@uarestrong76 Yeah, the pain from my peptic ulcer was referred to the other side of my body. Which was a place I'd injured as a child and had recurring pain, so I didn't bother to see a doctor. If it had been in the correct place I wouldve gone immediately.

[@YuBeace]

@@uarestrong76 I used to have a lot of ear pains but no-one ever found anything. Years later a Nose-Ear-Throat specialist said to check my jaw; low and behold. It was my jaw.

[@MarkMcGhee-i5j]

I just want to say ‘thank you’ doc. Not many doctors actually explain in great detail of symptoms, or causes thereof, of what is actually making the human body so sickly. We have to rely on such info from google. Then, we don’t know whether to be overly anxious or hope for the body to overcome the state that it’s in. I have been regularly watching your videos for some time now and find them very interesting and educational. You actually use ‘easy to understand’ definitions and add a lot of clarity when needed. So, again, thank you so much for your videos. Why can’t all doctors be like you?

[@raven4k998]

do you burp blood?🤣🤣🤣

[@Killbayne]

one of the best things about this channel is that he always explains what things like Tychocardia and cauterization mean to someone who might not know

[@kotovalexarian]

During the 7 days of my COVID disease I only took TWO tablets of NSAID, only when the body temperature was above 38.0 degrees (Celsius). I NEVER use any meds in case of a temporary pain. I can't even imagine how people may be so reckless. This story doesn't seem real to me.

[@princeofmisrule775]

I used to take 16~ Ibuprofen capsules a day on work days. That’s 320~ capsules not counting the ones I was taking over the weekend. Needless to say I nearly died. I have had chronic pain since middle school and I’m going on 30 so this story hits close to home.

[@TheZachary86]

Try marijuana

[@Tomas-ml9nv]

Take dgl liquorice without glicine in the ingredients before meals and before bed. Gaviscon advance a tablet before bed too. Over time my acid reflux /ulcers have dissapeared.