ACTION POTENTIALS IN NEUROPHYSIOLOGY by Professor Fink

Review of the Generation & Conduction of Action Potentials. This Lecture reviews the opening & closing of Ion Channels, the Relationship between Stimulus Intensity & Response, the Relationship between the Electrical Refractory Period & Frequency of Action Potentials, and the Factors affecting Conduction Velocity (Diameter of Fiber & Myelination). Reference is made to concentration gradients, electrical gradients, ligand-gated Na Channels, voltage-gated K Channels, voltage-gated Na Channels, electrical polarity, depolarization, repolarization, hyperpolarization, Na/K-ATP Pumps, Subthreshold Stimulus, Local Response, Threshold Potential, Suprathreshold Stimulus, myelinating cells (oligodendroglia & Schwann cells), Nodes of Ranvier, Saltatory Conduction, Multiple Sclerosis and fibrosis.
Check-out professor fink's web-site or additional resources in Biology, Anatomy, Physiology & Pharmacology: www.professorfink.com
Down-loadable e-Books of the Lecture Outlines by Professor Fink can be purchased from the WLAC Bookstore at: wlac.redshelf.com/
“Hard Copy” Lecture Outlines can be purchased from the WLAC Bookstore at: onlinestore.wlac.edu/fink.asp

[@aformula4198]

It's 2022 and your work is still benefitting students

[@iloveromeo3]

Clearly a Professor who really likes his job! Thank you for posting for everyone.

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I wish there were more professors like you, professor Fink! 45 min of watching your video thought me more than weeks of classes have thought me at my university. THANK YOU.

[@sandyable]

BEST PROFESSOR IN EARTH!!!!

[@LiyunguKambeuka-od1ti]

I never thought it this topic could be made this easy, how I wish I could get some extra lessons with professor fink. Much love from Zambia 🇿🇲

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[@adrianacampodonico6502]

M A he should get a novel prize!

[@Amy-dn7re]

This Man should be celebrated.......wow wow ,i wish all Lecturers are like him.

[@sunnydulay5290]

I just wish more profs were like you prof fink! Thank you so much for your effort and dedication to actually making physiology make sense.

[@nyawirawaithaka4993]

Thank you Prof.Fink - Action Potentials FINALLY make sense! God bless you.

[@rafsanjani9207]

You are undoubtedly the best professor of Anatomy and Physiology. Hats of to you, Sir.

[@iqchip]

Holy cow, this guy is awesome. He's got a gift for delivering tough subjects in an easy to understand manner.

[@chimelogongoziobiegbu8610]

A genius indeed!God bless you

[@professorfink]

Thank YOU for your kind words. May God Bless You with much Success! -- professor fink

[@mikepict9011]

Best teacher on KZbin. I feel like I'm stealing

[@NobleTenz]

This professor deserves an award👍Thank you for sharing

[@SmileDreamFall]

Thank you so much! I've revised my entire semester's worth of work from your videos, thank you so much!

[@gambo23xx]

man, what a lecturer! thank you for sharing this video with us, really helps

[@happymeltedcity]

Every time he slaps his hand the hungover guy in the back of the class wakes up.

[@SholupToklo]

You're an amazingly gifted lecturer. Talking concepts into humans is such a complex and challenging task. To do it well is almost a miracle. Congratulations on your contribution to our collective evolution of knowledge!!!👏👏👏👏🙆🙏

[@professorfink]

Dear Hannah, Thank You for your kind words. I truly appreciate it. Best Wishes, professor fink

[@bless1012]

He is so passionate. I love his lectures so much.

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This is awesome.. i freakinly love this lecture.

[@thithinwehtun]

I am so blessed to listen to your lectures everyday

[@Lisa.pizzza]

Amazing Professor! I am starting to understand.

[@adrianacampodonico6502]

I wish I had you for all my clases!!! Your students are beyond lucky

[@YOsorio]

Thanks Prof. Fink you're awesome!!!

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Awesome lecture. Thanks Prof. Fink!

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thank you so much for your uploads! you are an amazing lecturer!

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thank you lecturer for your best video lectures .

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Thanks is not enough ....you are awesome ....god bless you

[@ArgentDawn55]

Thanks for uploading im going to watch it again

[@mohammad.salehi19853]

Excellent

[@ngozinwanma379]

God bless u a million times

[@professorfink]

Thank YOU! And May God Bless You.

[@bless1012]

aww, he is just adorable when he teaches...

[@catchie2U]

WOW. you clarified soo many things. thanks! :) I can see that you are a very good professor, by the way you teach:D

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nice method of teaching

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Come and be my lecturer !!!! PLEASE !!

[@user-gy7hh7hq7v]

you're awesome ❤️❤️❤️❤️

[@FallButterfly]

I'm taking human physiology and I understood nothing from my prof. now I found out how fun physiology is!! thanks a lot ... at what school is this?!

[@adrianacampodonico6502]

Professor Fink, I’ve been watching your videos for a couple of years and they have helped me tremendously. I just have a question, does MS affect schwann cells BECAUSE it affects oligodendroglial cells? You mentioned it affects the myelin sheath in both the CNS & PNS. I keep coming across sources that say it only affects oligodendroglial cells, since MS only affects the CNS? I know this is a very complex topic that confuses me. Could you explain to me how MS affects schwann cells? Thank you 🙏🏼

[@Njubish]

Such a good tutor! I was struggling with this subject and this helped me understand it so well. I'm just a bit confused, since my book states the cell contains Chloride (Cl-), while the slide shows A-, which I don't know what is.

[@shaunw548]

He uses A- just to show the various anions present. He doesn't specify individual elements, although he has mentioned Chloride.

[@yazir123]

Hi Professor I was wondering if you have uploaded any videos concerning action potential, but its changed due to influences and how the action potential would change, such as the opening of both the potassium and sodium channels at the same time, also how the action potential would change if there was no inactivation gate on the sodium channels

[@ijasahammed1630]

What happens to the previously mentioned leak channels... Once the sodium channel is opened during depilarisatiin... Will the pottassium simultaneously diffuse out due to change in gradients

[@LiyunguKambeuka-od1ti]

Anyone help.Which part of the graph is the membrane potential (Vm) closest to Na+ equilibrium potential.

[@kemonroe3422]

Professor Fink, I've been watching your lectures online, it helps me a lot in my current Physiology class, and I really enjoyed i! I just finished the action potential, I know that supra threshold stimulus does not give bigger APs than threshold stimulus, it just gives more APs during same time period, and I know that usually the highest peak of an AP is about 30mV, but would there be variations of this peak mV, could some cell have the peak of 20mV, 15mV etc.? What would be the reason causing this variation? Thank you!

[@professorfink]

+Ke Wei Monroe Any variation in the "peak" of the Action Potential is related to the "Equilibrium Potential" for Na+. This could be affected by slight changes in the relative amounts of Na+ outside and inside the cell.

[@kemonroe3422]

+professorfink Thank you so much!

[@footballislife3821]

Do post everything u knew in physiology sir please

[@cu99460]

Where can we get a copy of your lecture notes?

[@hafnium5022]

can you please tell me what happens to the sodium-potassium leak channels during depolarisation and do negative ions have any role to play in conduction of impulse..?

[@ijasahammed1630]

Yes bro me too with same question

[@ijasahammed1630]

Did you get the abswer

[@ijasahammed1630]

Inform pls

[@user-gy7hh7hq7v]

they get inactivated during action potential.

[@RAIN_VIDEOS-722]

Thank you ..but can i ask you something

[@ebenezerrowland]

He is just exclusive

[@luiz19169]

how i get his notes

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[@NobleTenz]

What school is this?

[@wafikiri_]

Actual facts about electrical conduction in a wire: · Electrons move at an average 4 metres/second only in good electrical conductors! Yes, they are extremely light, but they do this: they rapidly accelerate in the vacuum between two wire metal atoms, then they are suddenly stopped as they crash against them, and then these electrons spend some time in their respective atoms until they are newly released. But: · Electric signals in a wire travel at nearly the speed of light in vacuum, 300,000 kilometres/second, 186,000 miles/second. How is this possible? Easy: the moment an electron starts accelerating between two wire metal atoms, photons emitted from this accelerating electron travel at the speed of light and reach the nearby atoms, causing electric forces on their electrons so that they are released from their atoms almost as soon as the first, and they emit photons as well as they accelerate, that reach yet more atoms, repeating the process and propagating the electric signal. This signal, thus, propagates extremely fast even when the wire current electrons do extremely slowly.

[@professorfink]

+Wafikiri Excellent! Thank you for describing the "real physics" of electrical current. The main point that I was trying to make is that the current flow in a nerve fiber is much different than current flow in a wire. -- professor fink

[@arzoahmadi5821]

who keeps interrupting ? :-/

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nkkl

[@footballislife3821]

Just like dr.strange asking : teach me...

[@DavidBrown-gk3mw]

Electrons don’t move at the speed of light through a wire it’s about 1/100

[@professorfink]

Thank You, David. You are exactly correct regarding the speed of an individual electron in a copper wire. The more appropriate term for expressing the intended concept is "signal (wave) velocity", which is the speed at which the "electromagnetic effect" travels through the wire -- which is close to the speed of light. -- professor fink