ADMET Analysis | Pre-Clinical Drug Testing | CADD Step-4 | Lecture 36 | Dr. Muhammad Naveed

ADMET stands for Absorption, Distribution, Metabolism, Excretion and Toxicity. The prediction of the ADMET properties plays an important role in the drug design process because these properties account for the failure of about 60% of all drugs in the clinical phases.
Four phases of pharmacokinetics. The main processes involved in pharmacokinetics are absorption, distribution, and the two routes of drug elimination, metabolism and excretion. ...
Drug absorption. ...
Drug metabolism. ...
Drug excretion. ...
Concentration-time relationships. ...
Repeated drug dosing.
About Dr. Muhammad Naveed
Dr. Muhammad Naveed obtained PhD degree in Biotechnology (Genomics & Bioinformatics) from QAU, Islamabad with distinction. He has won PhD indigenous & IRSIP scholarships from HEC. He has done Pre-Doc research from University of Ghent, Belgium. HEC awarded best PhD (IRSIP) Scholar of the year 2013 & QAU honoured him as “Distinguished Alumni” in 2017. He is doing research in Bioinformatics & Molecular Biotechnology. He has supervised 25 MSc., 30 MPhil. & 01 PhDs. He has published 51 research articles, 01 book and 03 book chapters. He has been awarded distinguished “Researcher of the Years (2016, 2018 & 2019)” by UoG and UCP.
#ADMET #PreClinicalTesting #SwissADME

[@fatimanoor5424]

You are doing excellent job... Sir. No words for this help to us... Thanks sir

[@Prof.Dr.MuhammadNaveed]

welcome

[@noorulain1640]

How can do anylysis of more than one compounds in a single run using swiss adme and how can i download these results??

[@fun_zonealankrati]

Which kind of format we need to download for import the structure?

[@ammarahchaudhary2820]

Sir plzzzz ucsc k bare m bhi bataye Whan se primer Kaise pick r design karne hai aur sir real time K liye primer Kaise design karte hai Plzzzzzzzz deliver lecture on it.

[@Prof.Dr.MuhammadNaveed]

watch may lecture on insilico PCR from UCSC browser and will make a complete lecture on it

[@ammarahchaudhary2820]

Thanx sir for replying Students need these types of sir who is hardworking and give full dedication to their students and not jealous of student . Sir play an important role in the life of students and students also respect to theirl professor. Thanx sir for making these types of lecture but need all the minor details of bioinformatics lecture.

[@saeedjaanz]

Sir plz can you provide information or any guidelines about predicting gene duplication from a protien sequence?

[@Prof.Dr.MuhammadNaveed]

could you elaborate your query duplication in what way?

[@naughtynoor7308]

Firstly i would like to thank you for teaching us in a great way. Also, i have a query what if our drug lies in PGP+ region?

[@Prof.Dr.MuhammadNaveed]

then choose other compound

[@user-en4vs6nb9w]

How to check toxicity

[@Prof.Dr.MuhammadNaveed]

mentioned in results

[@sanjaisrao484]

Excellent explanation..thank yoy sir

[@Prof.Dr.MuhammadNaveed]

Glad to hear that its help you

[@NikhilSharma-in5tj]

Synthetic accessibility 3.94 ?? ye thik hai ya less effective hai

[@ritikavaid3224]

Sir pharmacokinetics ke parameter ki standard value ki who list kha se milegi

[@Prof.Dr.MuhammadNaveed]

literature