ADS1: Indexing and k-mer indexes

[@polycarpnalela6951]

Thanks for this short, but beautiful explanation

[@nicolel.4738]

Thank you so much! Your demonstration and book index analogy were very helpful :)

[@kirokamui]

great classes, thanks a lot!

[@henkb2523]

just for my understanding, I noticed that the letters GTGCG changed into GTGCC when index number 3 was inserted. Can I assume that this is an error ? Or is this supposed to be ?

[@ehsanalavi3427]

I did confuse me as well, I think it's an error!

[@Pankajdubey8706]

Thank you! Very well explained!

[@dc33333]

Very clear excellent

[@c.riccio8803]

How do you choose the best k, i.e. the k that will minimise the total amount of time of alignment?

[@mrinalvashisth]

www.ncbi.nlm.nih.gov/pmc/articles/PMC2784323/ as far as I know, to get the most unique alignments in case of humans a k-mer length of 33 is sufficient. If you have too little a k-mer length then we will get too many possible alignments (or little unique alignment) which is impractical. if you make k-mer length too high then you are going to miss important details such as insertions, deletions etc. because the k-mer will align very uniquely.

[@chunk032]

Thank you

[@eddyhuang9182]

It seems like there's a mistake. There's no substring "GTGCC", only "GTGCG"

[@onnichaleelastwattanagul5775]

Thank you!!

[@ahmedsayed3607]

thank you