Advanced Organic Chemistry: Protecting Groups

[@user-mp4bc9qp2x]

Still keep a copy of Greene's PGs on my desk. This video is another great reference material. Thanks to the Synthesis Workshop Team and the presenter!

[@aritrabarman8763]

Thank you very much for this valuable and essential lecture. I have a question:- Suppose we have a compound Ph-CH(OH)-CH2OH (containing secondary alcohol at the benzylic position and primary alcohol in the terminal position). I want to selectively oxidize that primary alcohol into aldehyde. Which protecting group should I use to protect that benzylic secondary alcohol selectively?

[@marosbella8857]

Thank you very much for a very useful and inspiring lecture. I got intrigued by a benzyl group deprotection on slide 5 by deprotonation with sBuli followed by treatment with trimethoxyborane and hydrogen peroxide. This was referred to Greene's Protecting groups in org. synthesis. Please, could you provide me more specific reference to this method. Thanks a lot in advance. Maroš

[@Chemicator]

Perfect👌