Advancements in second-line immunotherapy for cholangiocarcinoma

Do-Youn Oh, MD, PhD, Seoul National University College of Medicine, Seoul, South Korea, discusses second-line therapies and immunotherapies for cholangiocarcinoma. Currently, the standard first-line treatment includes nivolumab or pembrolizumab with chemotherapy. If the disease progresses, second-line therapies such as FOLFOX are used in the absence of genetic alterations. It is emphasized that the next step should be to develop new regimens that incorporate immune checkpoint inhibitors in this line of treatment. This interview took place at 2024 European Society for Medical Oncology (ESMO) Gastrointestinal Cancer Annual Congress in Munich, Germany.
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