AIDS and HIV infection (Detailed lecture)

Рет қаралды 126,100

Күн бұрын

The human immunodeficiency virus (HIV), the pathogen that causes AIDS, both escapes and attacks the adaptive immune response. Once introduced into the body, HIV infects helper T cells with high efficiency by binding specifically to the CD4 accessory protein. HIV also infects some cell types that have low levels of CD4, such as macrophages and brain cells. Inside cells, the HIV RNA genome is reverse-transcribed, and the product DNA is integrated into the host cell’s genome. In this form, the viral genome can direct the production of new viruses. Although the body responds to HIV with an immune response sufficient to eliminate most viral infections, some HIV invariably escapes. One reason HIV persists is that it has a very high mutation rate. Altered proteins on the surface of some mutated viruses reduce interaction with antibodies and cytotoxic T cells. Such viruses replicate and mutate further. HIV thus evolves within the body. The continued presence of HIV is also helped by latency while the viral DNA is integrated in the host cell’s genome.
This latent DNA is shielded from the immune system as well as from antiviral agents currently used against HIV, which attack only actively replicating viruses.
Over time, an untreated HIV infection not only avoids
the adaptive immune response but also abolishes it. Viral replication and cell death triggered by
the virus lead to loss of helper T cells, impairing both humoral and cell-mediated immune responses. The eventual result is acquired immunodeficiency syndrome (AIDS), an impairment in immune responses that leaves the body susceptible to infections and cancers that a healthy immune system would usually defeat. For example, Pneumocystis carinii, a common fungus that does not cause disease in healthy individuals, can result in severe pneumonia in people with AIDS. Such opportunistic diseases, as well as nerve damage and body wasting, are the primary causes of death in AIDS patients, not HIV itself. Transmission of HIV requires the transfer of virus particles or infected cells from person to person via body fluids such as semen, blood, or breast milk. Unprotected sex (that is, without using a condom) and transmission via HIV contaminated needles (typically among intravenous drug users) cause the vast majority of HIV infections. The virus can enter the body through mucosal linings of the vagina, vulva, penis, or rectum during intercourse or via the mouth during oral sex. People infected with HIV can transmit the
disease in the first few weeks of infection, before they produce HIV-specific antibodies that can be detected in a blood test. Currently, 10-50% of all new HIV infections appear to be caused by recently infected individuals. Although HIV infection cannot be cured, drugs like (HAART) highly active antiretroviral therapy have been developed that can significantly slow HIV replication and the progression to AIDS.
#AcquiredImmunodeficiencySyndrome
#AIDSAndHIVInfections

Пікірлер: 94

@aamirsohail4142 10 ай бұрын

I am from 🇮🇳 your lecture is so amazing sir ❤😊

@SANJUOO9 4 ай бұрын

Love ❤ from India 🇮🇳 your explanations is too Amazing Very helpful for me thank you sir

@kushawaha7702 11 ай бұрын

I from Bharat....but your explanation is osm sirrr ji

@Leonidas-qg3ku 9 ай бұрын

Mashallah sir your all lectures is very informative and awesome.. I am 1st year student I am learning and getting extra knowledge from your lectures... It's amazing

@Unknown07625 8 ай бұрын

Outstanding 🎉 the way of your teaching is speechless your hardwork and dedication will come in the flying colours 👏 Keep going on💯

@ShahanKhan-jc4mf 9 ай бұрын

Sir your are the best...the students you are teaching in school or clgs are lucky...

@zeeshansultan8572 Жыл бұрын

Great Lecture Sir Your Teaching Method Is outstanding ❣️❣️❣️

@Prince-Gaming47 9 күн бұрын

Great

@romaisaharoon9947 2 жыл бұрын

Your all lectures amazing

@user-pj4xr5et8q 8 ай бұрын

Sir allah apko hamisha Khush rakhe ........... mashalllah sir ........ bohot bohot thank you sir❤

@mustafa_pathan19 2 ай бұрын

Mashallah lajawab sir ji 😊

@SikanderAli-go3hg 9 ай бұрын

Great teaching dear sir and continue ❤❤❤❤❤❤❤❤❤❤

@user-vk4hw3hl5m 24 күн бұрын

Amazing lecture😊

@shalinikumari5878 6 ай бұрын

Amazing lecture

@shahidbajwa6871 2 жыл бұрын

Amazing sir .... I was searching this lecture on ur channel in today morning...

@sachinyaduvanshi4256 2 жыл бұрын

nice lecture sir

@Neha-mu1fj Жыл бұрын

Thankyou sir...apne bht acha padhaya

@Dreamnshayar 11 ай бұрын

जय श्री राम भाइयों ❤

@anikasharma00 11 ай бұрын

Jai Shri Ram

@abdurrehmankhanshinwarikha3200 Ай бұрын

Best explains

@Educationofintermediate._ 8 ай бұрын

How HIV and AIDS are closely related with each other?

@user-saimak2 10 ай бұрын

Thank you very much sir 😊😊

@samiaashraf6962 Жыл бұрын

Sir, your lectures really helpful, thanks 👍🥰

@hanzalakhan3989 2 жыл бұрын

Sir is chapter kai bd respiration chapter kai lecture upload kare

@arsalankazim954 8 ай бұрын

Nice lecture ❤

@dhaneshkumar-l7v Ай бұрын

hi sir i am 2024 come in 1first year becuse book will changed sindh text book so i am request to you make a new video

@rambelgongo3490 Жыл бұрын

Thanks bro its help.

@babykidsnurseryrhymes798 Жыл бұрын

ALLAH PAK SAB SAB KI HIFAZAT KARY AWR SATH MAY HAMARAY MAA BAAP KO BE ELAHI AMEEN SUMAMEEN ♥️♥️❤️♥️

@antimaharijan1666 Жыл бұрын

Sir post that Status epileptics in details plz

@saminakhatun4461 4 ай бұрын

Ma shaa Allah tabarakallah ❤

@kinzaqueen5194 Жыл бұрын

Gooood

@sajidkhn14884 7 ай бұрын

I am from afghanistan 🇦🇫 Great job

@chachavidhayak0716 Ай бұрын

@ShoaibKhan-fk7vi Жыл бұрын

👍👍👍👍 sir I like your lecture

@GalacticExplorations- 4 ай бұрын

feeling sad for Aids patients 😥😥

@daniyalaneeqahmed4296 9 ай бұрын

Sir I have a question. Sir ap ny likha he B lymphatic cell releases antibodies against antigens aur antigens pathogens hoti he aur pathogens microorganisms hoty he tu sir yaha pathogens sy tu virus muraad he na virus tu virus ko organisms nahi keh sakty . Sir please clear I am little bit confuse about that

@kamilkhan522 7 ай бұрын

Bro , pathogen is general terminology for all those living and nonliving organisms which can cause disease in our body❤

@mahrangbaloch8060 Жыл бұрын

Tbh: sir ap bohtt deep jathe hu to hum bohtt confuse hojathe hai zeyada deep na jahu plzz

@abdurraufabdurrauf7669 2 жыл бұрын

THANKS SIR G EXCELLENT PAKISTAN ZINDABAD ADDRESS LAKKI MARWAT NAME ABDUR RAUF LIKE LECTURE

@MustafaKhan-gl7dc Жыл бұрын

Good job brother

@user-saimak2 10 ай бұрын

Ma shaa Allah ❤❤

@iqramaryam1451 Жыл бұрын

Amazing work.keep it up.

@Rohan_800 Жыл бұрын

Sir kya dendrite of neuron mai vi HIV ho skta h usme vi CD4 receptor hota j

@ShahanKhan-jc4mf 9 ай бұрын

Yes dear...as sir said macrophages, dentritic cells,T cells have CD4cells so HIV can enter here

@abutuba627 2 жыл бұрын

Amazing sir...thank you 💞💞🥰

@UmaimaRajput-vy4rr 4 ай бұрын

Sir cd4 means??

@randheerkumar6507 2 жыл бұрын

Sath me neet ka questions bhi bataoi sir

@sherrysimpson9536 2 жыл бұрын

Wow surprisingly I'm now HIV negative thank you Dr Abiola for helping me get rid of HIV #drabiola 💙

@gullona5924 Жыл бұрын

Thanks sirr

@owais816 2 жыл бұрын

Sir is series mai kitnay lecture hai

@chotu5784 Жыл бұрын

@Beast_editor.1 7 ай бұрын

Jai shree RAM ❤

@mawais9370 Жыл бұрын

Outstanding sir ❤️

@pscnitro6414 Жыл бұрын

Usefull class sir...

@rehabmarkus4192 2 жыл бұрын

You are such a delightful and a dedicated traditional doctor Emuakhe on KZbin.you are truly an inspiration.i cannot thank you much enough for introducing your herbs that completely cure my HIV parmanently...

@Pinku134-b4t 8 ай бұрын

Ram Ram 🙏🚩🇮🇳

@mbbszone2022 Жыл бұрын

❤❤❤

@ilmakhan2221 5 ай бұрын

Waalekumassalam

@aizazjan8138 2 жыл бұрын

Amazing sir 😍

@JSBM910 Жыл бұрын

Ohh islamic rule ye kehta hai k ek legal partner hona chaiye. 😂😂😂😂😂😂😂😂😂😂😂😂. Tin tlaak tere us islam me hi h.. Masi bua ki ldkio se shadi krna. Tere islam me hi h... 20-30 bche paida krna b tere islam me h... Upr se bolte ho k alaah dera h bche.. 😂😂😂 Dubara nam mt le lio. Tere is islamic rule ka.

@ticreator6364 10 ай бұрын

Lafz Bta daithy hai Insan kaisa hai.

@JeOn776 4 ай бұрын

Oh my , shame shame go first search islamic rules without knowing don't judge my Islam unless person first lesson Islam tell about 4 marriage beacuse it's a man right , Allah also tell us that do what is right for health not this what you're talking about and I'm telling this from holy QURAN it's not fake it's holy book not written by humans like us first go and read QURAN you will know about the power of it and if you get bore ok no problem but first read every sentence of it you will feel what rubbish you're talking about so don't judge a book by its cover you're handu ok no worries , but don't interfere in Islam if u don't like it's your weakness to not find the rays of light so that's it , close your month and get lost ........