ALT, AST, ALP & GGT (Liver Function Tests) - How to Interpret

In this TachyTutorial, we explore the basic principles of interpreting Liver Function Tests. We explain what the enzymes ALT, AST, ALP, GGT and what the clinical significance is if their levels are raised. We also explain some special relationships between these enzymes!
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DISCLAIMER: This video is made for educational purposes only and is not made for medical advice. Please consult a doctor or other qualified healthcare professional for medical advice. The information in this video only represents the knowledge of the individual speaking in it and not those of any institution or other individual(s). We are not responsible for any errors or liabilities held within these videos.
#LiverFunctionTests #ALT #HowToInterpret

[@sadhucat4476]

Like everyone else here is saying - this is an amazingly digestible breakdown of liver enzyme analysis. I actually feel like I have some rough idea of how to interpret values now. Thank you!

[@TachyTutorials]

Thank you for watching!

[@HepatitisBChannelHepatitisB]

Seems way too dramatic bearing in mind everyone often has raised alt.... with every course of pain killers, pub visit, protein shakes use, junk food lifestyle and many passing infections. None of these raises represent liver damage... so maybe remove the damage and put back the function where it belongs

[@MrSmith-yr9vk]

For me, my higher than normal liver function tests revealed a silent problem that was going on. My ALT and AST started getting out of range growing higher each year (Over a three year period by the lab work results). My ALT hit 153 and AST was 88. ALT by the chart was over 113 past normal and AST was 40 points over. So what was causing my Liver to start hitting the panic button??? Well, an ultrasound of the liver showed the Renal Cell Carcinoma that was growing on my right kidney. MRI showed the tumor growing on my left kidney. From what I have read, the ALT enzyme reacts when the RCC gets into the renal artery. Well, two surgeries later, loss of right kidney and a piece of my left my numbers are back in range. I was in good shape, non-drinker, non-smoker, exercised everyday. If your numbers are getting out of whack and your Dr's tell you to stop eating fast food (That's what the dude told me, turned out to be Cancer) just make sure to keep looking at the problem. My bad Liver Function tests saved my life because I kept trying to find out why it was bad and I indeed found out why.

[@Neenah44]

Did you have any other symptoms?

[@MrSmith-yr9vk]

@@Neenah44 For RCC, not a single one. If I would have just done nothing, I probably would be Stage 3 or 4 by now. My Urologist said that if the tumors would have been reversed, the Ultrasound on my liver would not have seen the tumors and I would not have made 60. I was 46 when we found RCC Stage 2.

[@Neenah44]

@@MrSmith-yr9vk Thank you for answering me I appreciate it very much. I’m happy that you were persistent in finding out why your numbers were growing higher. You literally saved your life. A great lesson on advocating for ourselves! Thanks again. Happy new year! 😊

[@MrSmith-yr9vk]

@@Neenah44 Happy New Year to you and you are very welcome. RCC was not the answer I wanted to hear, but it was the answer to my problem so far.

[@ramathakur3667]

@@MrSmith-yr9vk bro.... i have ....258.0 - AST,471.9 -ALT,221.9-GGTP,447.00 - ALP ............ i was used to be proper in shape with 83 kg BW...now it turned into 73 in just 2 weeks.... i used to hit gym.... no alcohol ..even not fast food intake.... nd now i fukd upp

[@MomJ_]

No one can do better explanation than this. i really find value

[@TachyTutorials]

Thank you!

[@rosegallus4048]

All I can say is WOW! I could not understand these enzymes any better. I like the fact that you started by highlighting where each one of them is found and that made it very easy to Interpret the results. Im officially your subscriber from now.

[@TachyTutorials]

Thank you so much for your great feedback! Very useful! Glad you enjoyed and welcome to the channel!

[@stanleycates1972]

Excellent. Was diagnosed with autoimmune hepatitis and treated most of last year. Turned out to be an infected gall bladder.

[@jjohnson9822]

how u going now bro?

[@stanleycates1972]

@@jjohnson9822 good, except being 85. The body is worn out from overuse :)

[@ragavansrinivasan1961]

Good evening sir, were is treatment autoimmune hepatitis primary bailary colanjaitis.

[@damariskendrick2591]

Hello Mr Stanley Cates. Did you have to take prednisone or azathioprine? Asking because I had the same diagnosis and my gallbladder removed.

[@MsCarrionswarm]

Symptoms of infected gallbladder?

[@aparnabiju1575]

The best video out there on LFTs!! Thank you so much!

[@TachyTutorials]

Thank You!

[@rubidiumandi2334]

True

[@andrewadali6121]

@@TachyTutorials ,

[@ZahidHussain-ht4tw]

Right 👍👍

[@nickthrasher4948]

Mine was due to alpha1antitrypsin deficiency! I think everyone with the high levels should be checked for this today! It’s not an expensive test and needs an early diagnosis when possible🙏

[@obaahemaacandy9082]

This is the best explanation ever…..

[@oldschoolguy80s]

Amazing doctor! Thank you for the interpretation! 🙏👍

[@drhadizasuleiman717]

Your interpretation is amazing, i ws able to grasp it easily. Thank you so much, God bless you. Hadiza from Nigeria.

[@TachyTutorials]

Thank you for your support!

[@DrPrabhakarRao]

Excellent presentation to Doctors and Patients

[@jean-francoisduquette8336]

Hight GGT only is : Auto brewery syndrome is also known as gut fermentation syndrome and endogenous ethanol fermentation. It's sometimes called “drunkenness disease.” This rare condition makes you intoxicated - drunk - without drinking alcohol. This happens when your body turns sugary and starchy foods (carbohydrates) into alcohol.

[@ValentinaKajcinovska]

What if you don't drink and no it's not

[@edwardl.492]

i have elevated GGT and i get high from sugary drinks.. that made a lot of sense

[@DrNancyLivingCoCreatively]

I suggest you look into anti dressants. I have MTHFR c677t. My liver detoxes 70% slower. I allowed myself to be put on an anti present well butrin an enzyme I a had under control rose.

[@Orangina345]

What was high? I have ALP moderately high, GGT normal and. mTHFR mutation . Thanks!

[@MsCarrionswarm]

Antidepressants cause problem in liver?

[@praveenmadhubhashana4185]

Thank you... you saved many hours of my study time 🥰❤️

[@TachyTutorials]

Glad you found it useful 😊

[@jahajoel]

This is awesome. I have actually learnt alot from watching this and am glad I found your channel. Please can you give us tutorials on lipids profile as well

[@Gracey-yz8zn]

thank you so much for this video and the important information included herein.. had lab tests done and both alt were aboeve normal, the 2nd result was even higher than the 1st and ast also was above normal but abdominal ultrasound shows normal liver impression..

[@gafarolamilekanolanshile1714]

Thank you so much.... Best I have ever seen.

[@TachyTutorials]

Wow! Thanks so much 🙂

[@lizsave7204]

That truly was the best and most informative, easy to understand explanation ever. Thank you!

[@TachyTutorials]

Thank you for watching! 🙂

[@lettymelton6613]

Excellent presentation! Thank you very much!

[@TachyTutorials]

Appreciate the comments. Thank you very much

[@damariskendrick2591]

Thank you for this video.. God bless 🙏

[@TachyTutorials]

Thanks for watching 🙂

[@rayreyes8497]

Excellent explanation.

[@TachyTutorials]

😀😀😀

[@lb4660]

Tacky tutorials Can the DTaP shot raise AST if given directly before blood work?

[@delaagbeko-konu9893]

Well explained to my understanding. Thank you very much

[@vivekabhyankar6565]

Wonderful explanation. Keep sharing more

[@TachyTutorials]

Thank you for your support!

[@uatdks803]

excellant teaching

[@TachyTutorials]

🙂

[@ezvahedi1387]

great explanation, thank you very much

[@TachyTutorials]

Your welcome 🤗

[@pradeepkumarsrivastava5890]

In India, we frequently find ALT values in thousands, 2 to 3 thousand , in case of Viral hepatitis

[@naman20gupta]

Yes absolutely.. Patients need not worry as Hepatitis can cause ALT level as high as 10000 (as in my case). So be relaxed and get admitted under medical supervision immediately and you will be fine within weeks or maybe months..

[@akkuverma2328]

Hi, do ast to alt ratio more than 2 always due to alcholic liver disease?is it possible to a person who never consumed alcohol?

[@Gemsurbangarden]

What if you have high GGT (125) and slightly raised AST and ALT but normal ALP? Ultrasound showed fatty liver 18 months prior but since then the AST and ALT levels have reduced (although still elevated)

[@aintgonnaletuknow5758]

very clear explanation, thank you very much

[@naeemqureshi6485]

Great lecture.

[@TachyTutorials]

🙂

[@LearnNursingEasy]

Good explanation, animations superb.

[@TachyTutorials]

Thank You!

[@fridaespinoza945]

Amazing explanation!

[@TachyTutorials]

🙂🙂🙂

[@YaasiDominic]

Woow😮, very understandable

[@CCMforall]

Excellent explanation❤

[@JK-hf2cx]

Very clear video. What is the potential diagnosis please if there is an isolated abnormal ALT of 127? I am talking about a young nondrinker who does not so suffer from haemochromatosis. I mention haemochromatosis because his serum ferritin is also high, as is his creatinine. No viral hepatitis detected.

[@12mach]

Tell him cut pork out diet its high polysatured fats are higher than alcohol

[@mercyzengeni9391]

Genius. amazing explanations

[@TachyTutorials]

Thank You!

[@priscanaab9226]

Very educative

[@fatumafatuma4077]

Wow thank u for this eloquency 👏🏻👏🏻👏🏻

[@TachyTutorials]

Thanks for watching 🙂

[@phillipwalter8993]

ALP elevated by osteoblasts,so bone disease perhaps but technically does not need bone destruction, so can differentiate early versus late Pagets on test questions

[@dettevalderrama5387]

Very good explanation...❤

[@huytiennguyen586]

Excellent explanation. Thank you.

[@TachyTutorials]

Thank you for watching!!!

[@justmontina]

Thank you so much for the clear explanation!

[@TachyTutorials]

Glad you found it useful 😊

[@mehrabmanteghian8071]

It was more than awesome! Keep up!

[@TachyTutorials]

Thank you! Glad you enjoyed 🙂

[@jonathanharina7556]

Doc my ast is 21.3 and my alt is 26.5 which the ratio is .80 that is less than 2, but my upper right abdomen is painful and the right side of my ribs, what is that doc? Could you enlightened me for that situation

[@DL-jf9fn]

Amazing video, thank you! if GGT, is raised and ALP is normal, accompanied by elevated AST and ALT (AST higher than ALT, but both raised), what is the likely outcome for that?

[@drendolob]

Alcoholism 🔥

[@brax5715]

@@drendolob what if you do not drink?

[@brothertn708]

How’s your liver doing now?

[@mudassarjabeen7548]

Yes ,u also want to ask , same reports,,can't interpret

[@mudassarjabeen7548]

@DL 0001

[@narminafandiyeva8875]

Thank you, that was very easy to absorb 🙂

[@TachyTutorials]

Thanks for watching 😀

[@bourethphay8136]

This is the amazing video 🎉

[@TachyTutorials]

Thanks 😀

[@asiaaslam4369]

Really superb

[@TachyTutorials]

Thank you so much! 🙂

[@isaackaddu]

Wow , Awesome thank you Doctor

[@andreatedtaotao2914]

Excellent presentation!!!! Thank you.

[@TachyTutorials]

Thank you!

[@tahirhussain4488]

Very nice explained

[@AKm-cs7ju]

That was really beneficial 🤌🏼

[@karenstanton5405]

Thank you l understand it better now

[@mariashieladolosa8239]

Thank you so much for this very informative video.

[@TachyTutorials]

Thank you for watching 🙂

[@stanceworks7995]

my blood tests came back and everything was good except my ALP was very low - what does this mean? The lab did not explain anything. Can this be the reason for Rosacea and/or weight gain? My AST and ALT were normal

[@EddyCor_Paris]

Very helpful video. Thanks a lot. 👍

[@S.BOfficial786]

The doctor told me my ggt level is slightly mildly raised im worried and dont understand this can you guide me more is this life threatening

[@spinedoc18]

Could raised ALT and AST be due to beta blockers and/or anti-coagulants?

[@ramankitbhai]

Can anyone plzz explain me the difference between liver infection and liver damage???

[@managbanagjoy]

What does it mean if there is no liver damage? Does it mean that it is functioning well?

[@DoinMaBestt]

Great vid Thanks!

[@TachyTutorials]

Thanks for watching 🙂

[@RCRM22]

Fantastic video. Thank you

[@annebeauclair5918]

what about NAFLÐ (non alcool fatty liver disease)?

[@ThePartyyChat]

Exactly this video is dumb trying to scare people

[@derickmartis220]

good info thanks

[@rishabhmishra537]

for alt, ast, alp liver function test are very well treated by planet ayurveda even i was a patient of liver i got relief after taking medicines from planet ayurveda

[@b.b.finsclara3589]

Upon getting my Bloom simple tests results.....de hace discovered i am experiencing "LowLevels of GamaGlutamylTransferase" I am uncertain what that implies....i do know i am experiencing VeryLowEnergyLevels????

[@CatsAreNiceMeow]

I was diagnosed with fatty liver but my doctor said it is unnecessary for me to have a GGT test performed. Is this true?

[@charlesnya5766]

What could a high AST:ALT ratio (>2) with low to normal GGT suggest?

[@Chrissy0325]

My alt is 20 and my ast is 20. This is the second time they have been the same. Is the ratio important to look at? My ALP is within normal limits and my doctor didn't comment on it so I don't know if I should bring it up. I have been diagnosed with fatty liver in the past with NASH 1 but I lost about 50 lbs since then but gaining 15 back. My last CT Scan did not show fatty liver so I am just concerned about the ratio since my 15 lb gain.

[@Jeswin_Jose]

Did you get the answer for your concern?..I also want to know whether the ratio is important or the values of AST and ALT are important.

[@toniaschianodicola2344]

Well explained

[@TachyTutorials]

Thank you! 🙂

[@ancabostinariu6550]

Thanks great summary.

[@TachyTutorials]

🙂🙂🙂

[@chrissoucy5322]

Can elevated diabetes numbers cause elevated elevated liver enzymes

[@NurseQuipy]

Normal AST &ALT but alightly high GGT ( results 43 &51) can chemo do this?

[@eyob-x2n]

Thank U

[@darkmoon3646]

U absolute gem Thankyou

[@TachyTutorials]

Thank you so much! 🙂🙂🙂

[@andradesaav]

Awesome video! New sub man

[@TachyTutorials]

Thank you so much!

[@johnbonamigo5696]

So with a small raise in GGT on blood test but all others are fine is most likely cause I drank a shit ton of alcohol 4 days before during a crazy weekend?

[@stronger3381]

ty 4 the awesome video

[@TachyTutorials]

Thanks for watching 🙂

[@zhenarwrya8808]

Got ur subscription deserves it

[@Cand.yasmin]

What if I only have elevated GGT but I don’t drink alcohol?

[@KingSlayer-qm6vi]

Great analysis but i suggest you to use better microphone for sound quality

[@KULDEEPSINGH-zr9vw]

Very informative

[@TachyTutorials]

Thank you!

[@asiahwalid6178]

Thank you!

[@TachyTutorials]

Your welcome 🙂

[@user-ou8pe9it8j]

What about Liver Steatosis? NAFLD?

[@vila4530]

Thank you so so much 😍😍

[@TachyTutorials]

Thanks for watching 🙂

[@billwilson6199]

Alt 40. AST 30. Alp 47. Ggt 85u/l. Have not drank alcohol for 5 years. What’s up with ggt being 20 points out of range?

[@estelamino6356]

Thanks

[@ionut4k280]

AST alt also in the muscle found so it’s false reding only good one is ggt on liver

[@obimpehbenjaminteye9100]

What if both alt and ggt raised.?

[@sunilpanday1785]

Good explanation, thank you

[@TachyTutorials]

Thank You!

[@SarathKumar-rz9pb]

Best video

[@TachyTutorials]

Thank you for watching 🙂

[@vacaspen5038]

very helpful thanks

[@TachyTutorials]

Thank for watching! 🙂

[@gulumamu2472]

i am hep b patient what test results interpret that i am in danger or out of danger?

[@rogerv2784]

Hello, my GGT numbers are coming out to 111 other than that everything else is good. I have over a year and a half with out drinking alcohol just recently i had 1 drink thats it. What are the factors that could be causing my numbers to continue to increase? And is it reversable? If so how can I drop the numbers?

[@pavanpabbireddypavanpabbir1897]

My ggt level went to 166 and i dont know what to do? Any suggestuons ?

[@timh-c7186]

​@@pavanpabbireddypavanpabbir1897 ...suggest low carb/keto diet

[@timh-c7186]

sugar causes high GGT, as I understand it

[@praveennaidu9873]

My ast 52.8 and alt 86.1....sap 103 pl suggest it's ok

[@parvinmuseyibova8743]

My daughter's AST and ALT increases when she is constipated. She has chronic constipation. When it gets better by the help of supplements her AST and ALT immediately decreases.

[@arlenebayron2448]

My gastroenterologist said constipation doesn’t affect the liver. I don’t believe him..

[@monanaveed7894]

My ALT and ALP is mild raised after my C section surgery. What could be the cause

[@RAWRitzLiZzi]

did you find out the cause?

[@monanaveed7894]

@@RAWRitzLiZzi dehydration may be and alot of antibiotics and painkillers use after surgery

[@augustfinn5704]

Thank you thank you thank you! ❤️

[@TachyTutorials]

Thanks for watching!

[@ragnaricks]

I am 25 yrs old and my ALT came out 157.9 and AST at 78.7. WTF, can this still be lowered? It is 3x and 2x of the normal levels

[@densilcardna]

You got a subscriber.

[@TachyTutorials]

Thank you and welcome to the channel! 🙂

[@densilcardna]

@@TachyTutorials Thank you.