Anti Gout Drug (Part 02) = Classification and Mechanism of Action of Drugs Used in Treatment of Gout

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Gout is a common, painful form of arthritis. It causes swollen, red, hot and stiff joints. Gout happens when uric acid builds up in your body. Uric acid comes from the breakdown of substances called purines. Purines are in your body's tissues and in foods, such as liver, dried beans and peas, and anchovies. Normally, uric acid dissolves in the blood. It passes through the kidneys and out of the body in urine. But sometimes uric acid can build up and form needle-like crystals. When they form in your joints, it is very painful. The crystals can also cause kidney stones.
Often, gout first attacks your big toe. It can also attack ankles, heels, knees, wrists, fingers, and elbows. At first, gout attacks usually get better in days. Eventually, attacks last longer and happen more often. Gout occurs when excess uric acid (a normal waste product) collects in the body, and needle‐like urate crystals deposit in the joints. This may happen because either uric acid production increases or, more often, the kidneys cannot remove uric acid from the body well enough. Certain foods and drugs may raise uric acid levels and lead to gout attacks.
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[@BS-lf5zw]

Sir kindly reply as why some people with ua level higher the saturation point does not show any symptoms of gout?

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Both can be possible.

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Steroid analgesics use bhi to kr skte hai Pethidine tramadol NSAID se bhi ache hai ye to sir ji

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Ha hota hai but mainly pain aur inflammation ko sath me control karna hota hai

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Sir anti gout drug ka side effects kya kya ha

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[@ketanpatel3991]

Sir i have one doubt…uric acid cycle is takes place in our regularly or it is specifically takes place in gout disease ?

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Its excessive in gout

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Hello sir I'm doing masters in pharmaceutics but I'm so confused my research topic is anti gout drug but I'm not getting on which drug can I work for my project ?

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[@anilkfr]

My uric acid 9.5 mg ... gout with inflamation .... Kindly suggest in short name of the medicine for me

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Thank u sir.

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sir why diuretics are not given in gout?

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It will conc. Uric acid

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Next topic sir Bioassay

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Next unit will- Endocrine

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More than 1000

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Any advice for gout patients?

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Avoid protein diet

[@31_hardikgoswami76]

Sir one question ...why Aspirin is contraindicated?.what is the reason What effect it will show when we give Aspirin? Aspirin will effect the diuretic that is the reason

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because it can inhibit the excretion of uric acid, which leads to increased levels of uric acid in the body.

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sir is this topic present in kD tripathi

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Yes

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Alcohal is a source of purine,,ye apko mentioned karna chaiye tha

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Sir ye uric acid Crystal eliminate Kyu nhi ho pate h

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Hyper hone se te deposit hote hai.

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Pharmacology ka paper h sirji.. Kal...

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Why asprin not used in gout patient

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prolong and intensify an acute attack

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