Antimalarial Drug (Part-03) Casual & Suppressive Prophylaxis of Malaria | Malaria Treatment

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Malaria is a life-threatening disease caused by parasites that are transmitted to people through the bites of infected female Anopheles mosquitoes.
Malaria is caused by single-celled microorganisms of the Plasmodium group. The disease is most commonly spread by an infected female Anopheles mosquito. The mosquito bite introduces the parasites from the mosquito's saliva into a person's blood. The parasites travel to the liver where they mature and reproduce. Five species of Plasmodium can infect and be spread by humans. Most deaths are caused by P. falciparum because P. vivax, P. ovale, and P. malariae generally cause a milder form of malaria.
The signs and symptoms of malaria typically begin 8-25 days following infection, but may occur later in those who have taken antimalarial medications as prevention. Initial manifestations of the disease-common to all malaria species-are similar to flu-like symptoms, and can resemble other conditions such as sepsis, gastroenteritis, and viral diseases. The presentation may include headache, fever, shivering, joint pain, vomiting, hemolytic anaemia, jaundice, haemoglobin in the urine, retinal damage, and convulsions. In the life cycle of Plasmodium, a female Anopheles mosquito (the definitive host) transmits a motile infective form (called the sporozoite) to a vertebrate host such as a human (the secondary host), thus acting as a transmission vector. A sporozoite travels through the blood vessels to liver cells (hepatocytes), where it reproduces asexually (tissue schizogony), producing thousands of merozoites. These infect new red blood cells and initiate a series of asexual multiplication cycles (blood schizogony) that produce 8 to 24 new infective merozoites, at which point the cells burst and the infective cycle begins.
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[@arshisiddiqui7657]

Amazing Amazing Amazing lecture....thank u so much sir ....these lectures are like blessing for us (MBBS students)...thank u once again

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My pleasure. Thank you so much for your feedback

[@vrijendra_maurya100]

Thank you so much sir❤❤❤❤

[@meghana0829]

Your class is really helpful sir,I'm watching your class as a reference after completion of my online class.. In these pandemic days..online classes are going on ..let me tell you straight that my online classes are going really worst!!sometimes it make me feel how I ll show excellence in semesters!!a few days back I see your channel..and I'm in it👍🙏thank you sir..

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Thank you so much for your valuable feedback. Such feedback really become helpful for us. Tc and all the best

[@rashidulbsmmu]

The way of ur explanation is so easy

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[@wakilzada1827]

Ap 1 1 lafz ke meaning karta hai muji buhut pasand hai main buhut achi tarah dekh rahi hu thank you so much

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Thank you

[@wakilzada1827]

Sir main to bore horahe hu kise our k lecture liken ap ka lecture main muji buhut maza ata hai

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Thank you

[@shaguftakhanam1273]

Scored.....8/10 😐......got answer.....thank you sir

[@solutionpharmacy]

Which answer

[@shaguftakhanam1273]

@@solutionpharmacy questions no 6.&8 I gave the wrong answers especially question 8 I'm confused fever in malaria is due to ( most specific) d word specific I'm confused and given answer to bursting of RBC....so...........I got my answer and satisfied...😊.. thanks

[@solutionpharmacy]

Shagufta Khanam Good. The world most specific has changed the answer.

[@uvsagu7]

Awesome sir ji 🙏🙏

[@rajeshyadav-pk2zf]

Good idea for anti maleria

[@discipleofreality-10]

8/10..I got my answers..thank you

[@solutionpharmacy]

Ok

[@skvaishnav6625]

thnku sir for is vedio k liy muj bhut jarutat thi

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Welcome

[@anirudhtiwari1658]

No words to describe Just commendable effort ✌️☝️👌😊

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Thank you so much

[@prachisinghkashyap8471]

Got 9/10 didn't read the most specific in cytokine question thanks sir

[@solutionpharmacy]

Good score

[@shaileshmaurya9381]

Sir I'm just little bit confused in ferver malaria, But finally we got 10/10

[@solutionpharmacy]

Good. Yes thats a confusing options. Kinines are mportant

[@AnkitChoudhary-fz6pl]

Informative video sir

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Thank you

[@Bosz-lx6zv]

Discuss the rationale of use of antimalarial drugs one week before and 4 weeks after leaving malarial zone?

[@pharmacologists..5848]

Hello sir ... U did one mistake in last 20 second... You did add 1st lecture screen shot instead the today lecture 1st board picture 😃... But sir be honest your lecture is most important & effective for us..... Thank a lot for it sir😍😍

[@solutionpharmacy]

Ohhhh. So sorry for this. Bad luck i cant change it now.

[@wakilzada1827]

Thank you very much sir g

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Always welcome

[@pharmacistaltamashansari6668]

7/10, thanks alot sir

[@solutionpharmacy]

Good

[@mdquamrealam7028]

9/10, Thanks a lot

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Good.

[@neerajrao9217]

Thank you sir 😊

[@solutionpharmacy]

Neeraj राव सहाब my pleasure

[@prabhjotkaur2434]

🙏🙏 thank u sir ..u r great👌

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Thank you

[@abhinavpharmacy7503]

Perfect explanation sir... Lockdown me ..book ni laya per kmi feel ni hone di aaapne...

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Thank you. Best compliment for me

[@abhinavpharmacy7503]

sir do you have records of my test responses is I am doing well or need more effort

[@rajivdas8185]

Excellent

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[@vidushichandra9757]

sir, in KDT, sulfadoxine is given as 1500mg instead of 150 mg. your videos are very useful, thanks a lot

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Cinditions may different

[@manishpatidar765]

Good sir

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Thank you

[@sapnathakur7217]

Sir you're the best 🤟

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Thank you so much

[@trishapharmacyworld8346]

Thankyou sir 🙂

[@trishapharmacyworld8346]

8/10 thanks a lot sir

[@solutionpharmacy]

Good score

[@vibhapatel7918]

Tussi great ho sir 🤗

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Thank you

[@rajuryadav7972]

Socre 8/10 thank u so much sir

[@solutionpharmacy]

Good

[@vibhapatel7918]

Thanks sir for score 9/10

[@solutionpharmacy]

Good

[@majeedullahullah2243]

Sir hamay kesa pata chalega ki ye blood main hay or liver main....???

[@solutionpharmacy]

Diagnosis

[@vibhapatel7918]

Osm lecture

[@solutionpharmacy]

Thank you

[@zulfaabdulnasir]

Scored9/10...sir fever in malaria is due to brusting of RBC aur release of cytokinines?

[@solutionpharmacy]

Bursing of RBC may not cause fever but release if cytokinin will 100% cause fever and other symptoms.

[@zulfaabdulnasir]

@@solutionpharmacy ok sir

[@pharmacistaltamashansari6668]

Malaria is fever due to all above correct answer sir

[@solutionpharmacy]

No. Cytokines is right ans although infm comes under that

[@11.ruchatiwari31]

What is difference or similarities between dengu & malaria ??

[@solutionpharmacy]

Both are different disease and type of MQ

[@shrutivashishth23]

Sir book me sulfadoxine ki 1500mg dose h Or aapne 150mg btayi h plzz btaye kya book me mistake h........

[@solutionpharmacy]

I will check. Please share book image in our mail id- [e-mail]

[@shrutivashishth23]

Ji sir

[@pharmacistaltamashansari6668]

Sir antioxidant are balance free radicals in the body

[@solutionpharmacy]

Means ?

[@pharmacistaltamashansari6668]

Antioxidant kya hota hai

[@sunilkumaryadav808]

Sir android phone me notes 📝 ko download ker skte hai kya,🤔🤔🤔?

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[@ajayanayak9404]

Sir please make video about all system i.e endocrine, circulatory, respiratory system etc.

[@solutionpharmacy]

Already uploaded

[@veronicakhonai8278]

@@solutionpharmacy sir can u please send the link for the explanation of all system?

[@solutionpharmacy]

@@veronicakhonai8278 check in channel

[@FarhanKhan-ri6wh]

Sir 2nd or 3 rd trimester k meaning kya hai kon s month s dete hai

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9 months ko 3 se divide kariye

[@FarhanKhan-ri6wh]

@@solutionpharmacy 6 month 2nd 9 month 3 trimester hoga

[@MohitSoni-ok1he]

Great work sir , really appreciating meathod of teaching ,and sir when will you give lacture on disinfectant ,and chemotherapy of cencer ,anticeptic?

[@solutionpharmacy]

Mohit Soni anticeptic is not in syllabus. Cancer will come soon

[@MohitSoni-ok1he]

@@solutionpharmacy ok thx sir 😍

[@shuvadipbhowmik7632]

Sir online test ki last question 'no correct answer' show kar raha hai.sir please dekhia.

[@solutionpharmacy]

Corrected. Last question kaun sa

[@shuvadipbhowmik7632]

@@solutionpharmacy fever in malaria cause due to iss questions ka abhi answer dekha raha hai.my score 9/10 . Thank you sir for your hard work and effort.

[@ritukalita7793]

Fever in malaria is cause due to release of cytokines n other inflammatory mediators sir so the answer will be all of these but no correct answer was given on quiz pls let me know..

[@solutionpharmacy]

Its due to release of cytokines. Most specific ans.

[@rahul.9127]

Cytokines is correct answer mostly the cause of fever 🤒 But in case of release of the other inflammatory mediators is not the right cause of 🤒 fever Because release of inflammatory mediators in case of asthma & inflammation in bronchi ("bronchitis") due mostly the allergens & other factors FEVER 🤒 is not seen 👀 and there is no involvement of fever Majority of cases the cause of fever is the release of cytokines due to various factors and some other factors..........

[@rahul.9127]

@@solutionpharmacy Cytokines is correct answer mostly the cause of fever 🤒 But in case of release of the other inflammatory mediators is not the right cause of 🤒 fever Because release of inflammatory mediators in case of asthma & inflammation in bronchi ("bronchitis") due mostly the allergens & other factors FEVER 🤒 is not seen 👀 and there is no involvement of fever Majority of cases the cause of fever is the release of cytokines due to various factors and some other factors..........

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Regards

[@इंडियनआर्मी-व9ठ]

Sir onlain clas kitni bj lt h ap

[@solutionpharmacy]

09:00 PM

[@PHARMA8954]

❤️

[@omkarpandey8183]

Sir mujhe D pharma 2nd year ki pharmacology ki notes provide kr dijiye

[@vibhapatel7918]

Last question ka ans bta dijiye

[@solutionpharmacy]

Release of cytokines

[@vibhapatel7918]

Thank you so much sir

[@pallabipal971]

Sir causal prophylaxis Not casual Otherwise great video Thanks a lot

[@solutionpharmacy]

Sorry. Some time concentration of mind dont support.

[@harry6489]

5th part is missing !!

[@solutionpharmacy]

Ajay pal Singh not missing. See in channel

[@iftekharahmed1114]

8/10

[@solutionpharmacy]

Good

[@iftekharahmed1114]

Thank you sir

[@shitlafacts1550]

❤❤❤

[@dr.chandrakantmagdum1735]

👌🌹

[@avijitbej2683]

9/10 thank you sir. But 8 no question answer (d)all of the above, hona chaiye

[@solutionpharmacy]

Good. Nhi cytokinins hoga. Inf. Comes under it.

[@deepanshupandey5594]

Again 8 What is the answer of last question

[@solutionpharmacy]

Cytokines

[@vrijendra_maurya100]

Thank you so much sir❤❤❤

[@ashuhooda1012]

thank u so much sir