Antitubercular Drug (Part-03) Isoniazid | Mechanism of Action of Isoniazid | Isoniazid | Anti TB

Participate in the FREE online test for this lecture - forms.gle/wY3n...
Download the "Solution Pharmacy" Mobile App to Get All Uploaded Notes, Model Question Papers, Answer Papers, Online Tests and other GPAT Materials - play.google.co...
Tuberculosis, also known as TB, is a contagious bacterial infection that can be found nearly anywhere in the body. Bacteria of tuberculosis may communicate to one person from another by direct contacts like coughing, sneezing, or transmission of air. Tuberculosis is a chronic granulomatous disease infected by Mycobacterium tuberculosis. Tuberculosis is a treatable, communicable disease that has two general states: latent infection and active infection.
Active Tuberculosis- Active TB is an infection in which the TB bacteria are rapidly multiplying and invading different organs of the body as they are inactive condition. A person who is suffering from active pulmonary TB disease has a strong possibility to spread this infection to others by airborne transmission of infectious particles coughed into the air.
Latent Tuberculosis- Many people how received the infection of TB may not get infected with it immediately. The most common diagnostic test for TB is a skin test, The skin test for TB, otherwise known as a Mantoux tuberculin test.
Classification of Antitubercular drugs-
(1) First-line Antitubercular drugs- Isoniazid, Rifampin, Pyrazinamide, Ethambutol, Streptomycin
(2) Secon line Antitubercular drugs- Ofloxacin, Levofloxacin Moxifloxacin, Ciprofloxacin, Rifabutin, Terizidone, Cycloserine, Rifapentine, Ethionamide, Prothionamide, Paraamino-salicylic acid (PAS), Amikacin, Kanamycin, Capreomycin
(3)Third line Antitubercular drugs- clofazimine, linezolid, amoxicillin, clavulanate,
Mycolic acids are long fatty acids found in the cell walls of Mycobacterium tuberculosis the causative agent of the disease tuberculosis. They form the major component of the cell wall of mycoplasma species. Mycolic acids are composed of a longer beta-hydroxyl chain with a shorter alpha-alkyl side-chain Each molecule contains between 60 and 90 carbon atoms. M. tuberculosis produces three main types of mycolic acids: alpha-, methoxy-, and keto-. Alpha-mycolic acids make up at least 70% of the mycolic acids of the organism and contain several cyclopropane rings. Mycolic acids have been involved in maintaining a rigid cell shape but also they contribute to the resistance to chemical injury and to the protection of cells against hydrophobic antibiotics.
Get in touch with the solution by just clicking following links-
Facebook Group- / solutionpharamcy
Facebook Page- / pharmavideo
New channel (Pharmacy Dictionary) - / @pharmacydictionary
Instagram- / solutionpharmacy
E-Mail for official and other work - [e-mail]
LinkedIn- / pushpendrakpatel
#solutionpharmacy #Pharmacologyclass #GPATonlinetest

[@mayankmehendiratta999]

*Correction* Aluminum hydroxide in interaction point....

[@solutionpharmacy]

Mayank Mehendiratta ok what should be corrected ? Explain so that we may update

[@mayankmehendiratta999]

@@solutionpharmacy Replace albumin hydroxide with aluminum hydroxide

[@solutionpharmacy]

Mayank Mehendiratta yes. Thank you. Dear all please forgive me for the mistake made by me. Kindly correct thar point. Replace albumin with aluminium

[@mayankmehendiratta999]

@@solutionpharmacy Please don't write forgive me like that.....How can i judge u? it's just a minute mistake... pinning my comment is enough

[@solutionpharmacy]

Mayank Mehendiratta Ok. Thank you

[@uvsagu7]

The method of teaching is very impectful thanks sir...

[@solutionpharmacy]

uv sagu thank you

[@mariyahafeez6625]

sir u r the best teacher i have ever seen...me ne sari pharma ap ki videos se prhi h bht acha prhaty h ap.. may ALLAH bless u many more

[@solutionpharmacy]

Thank you so much.

[@yameenkhan3755]

Really aap ke sabhi videos superb h. 😍😍👍👍👍👌👌👌

[@solutionpharmacy]

Thank you so much

[@vrijendra_maurya100]

Thank you so much sir ❤️❤️👍👍

[@MKMediGuideLectures]

you are great Sir, I am deeply inspired by you and your method of teaching, really love it.

[@solutionpharmacy]

MK MediGuide Lectures thank you so much

[@dilipkalita5254]

Very frankly and good teaching methods

[@solutionpharmacy]

Thank you so much

[@sambitdas5065]

Outstanding explain sir 🙏 I always ever grateful to you sir 🙏🙏🙏🙏🙏🙏🙏

[@riazrahi69]

Outstanding sir love from Pakistan ❤❤❤

[@solutionpharmacy]

Thank you so much

[@dharmendragamad5001]

Thank u sir ji

[@shashikantkumar3683]

Thank you sir 🙏🙏 for giving yr precious time in lockdown 👌👍👍

[@solutionpharmacy]

Shashikant Kumar my pleasure

[@nitinpal6872]

Nice sir

[@kalpanasolanki7834]

Great teacher....V. nice explanation

[@solutionpharmacy]

Thank you so much

[@darshankumar30]

It's a good lecture sir keep going. I m preparing for my pg exam it's a nice brush up video

[@solutionpharmacy]

Thank you so much

[@ydb6061]

Very nice animation with explanation thank u sir ..

[@solutionpharmacy]

Thank you

[@ShabirAhmed-ov3ql]

Excellent lecture.......👍👍.. Thank you sir..🙏🙏

[@solutionpharmacy]

Thank you gor your feedback

[@sapnakumari7575]

Thank u so much sir 🙏🙏🙏

[@solutionpharmacy]

My pleasure

[@animalstv6602]

Wonderful

[@85kanadmayekar26]

Thank u so much sirr! Couldn't be more grateful😊

[@solutionpharmacy]

Thanks alot. Its my pleasure

[@aarizkhan3515]

You are so great

[@MANISHKUMAR-rz5fv]

thanku soo much sir.....

[@mdnooralam4780]

Thanks sir Allah bless you

[@solutionpharmacy]

Shukria

[@lakhmeerjaan4824]

Thankyou sir Great lecture

[@solutionpharmacy]

Thank you

[@jasleenkaurdarroch1864]

Great video as expected

[@solutionpharmacy]

Thank you

[@sawnisharma1325]

Thnku sir

[@satya6830]

Excellent lecture thanks sir.

[@solutionpharmacy]

Thank you so much.

[@satya6830]

Sir I am a bpharm final student and preparing for gpat 2021.sir please guide me.

[@solutionpharmacy]

Cover all points which are given in bracket of almost every subject

[@priyagautam6969]

Thanks sir god bless u

[@solutionpharmacy]

Thank you

[@SnehaSingh-lv1mf]

My score 10/10 Thank you so much sir🙏🙏

[@solutionpharmacy]

Sneha Singh Good

[@Suriddha_Munshi]

Sir...wo 1st video me diagram me "tubercular cavity" jaha likha he..uske niche "peri..." krke jo likha he..wo thoda samjha dijie..please

[@solutionpharmacy]

Uska screen shot bejiye mark karke mail me. Mai reply kar dunga.

[@FarhanKhan-ri6wh]

Thank you sir

[@solutionpharmacy]

Welcome

[@nehasultana1415]

Then it's better to give Isoniazid alone na sir..?? Why are v giving with Dizopam,etc etc.. N han sir class was very interesting thank uh sir🤗

[@renukabhagyawan1332]

Thank u sir 🙏

[@solutionpharmacy]

Welcome

[@rahultamang8324]

I got 10/10

[@veerendrayadav1357]

Tq sir ji

[@solutionpharmacy]

Welcome

[@mohdsaif3469]

Mycobacterium tuberculosis kiska saath combination ma dena ho gha sir

[@Anastesia2]

🌟🌟🌟🌟🌟

[@Siddheshgavankar28]

🙏🙏🙏🙏

[@dikshagurditta5059]

9/10

[@arshikhanam428]

sir INH meaning ? When isoniazid entered in cell ....

[@MKMediGuideLectures]

INH = isonicotinylhydrazide

[@solutionpharmacy]

MK MediGuide Lectures Both are interchangably

[@MKMediGuideLectures]

@@solutionpharmacy Yes Sir, thank you Sir😊🙂

[@jasleenkaurdarroch1864]

Isonicotinic acid hydrazide

[@ashmitmehta7772]

Sir azole derivative par video ayega future mei?

[@solutionpharmacy]

Ha

[@vikasnarayangawhane2859]

correction in interaction "aluminium hydroxide "

[@solutionpharmacy]

Sorry

[@poojavarshney5547]

Aàd

[@yameenkhan3755]

Really aap ke sabhi videos superb h. 😍😍👍👍👍👌👌👌

[@solutionpharmacy]

Thank you

[@howareyoureadingwritinglet4959]

Thanks Sir

[@MANISHKUMAR-rz5fv]

thanku soo much sir.....

[@Rohitkumar-xg8pv]

Thanku sir ji 🙏

[@solutionpharmacy]

Rohit Kumar welcome

[@SnehaSingh-lv1mf]

My score 10/10 Thank you so much sir🙏🙏

[@solutionpharmacy]

Good one

[@yameenkhan3755]

Really aap ke sabhi videos superb h. 😍😍👍👍👍👌👌👌

[@solutionpharmacy]

Thank you

[@dhananjaysingh4133]

Thanks sir

[@laxmipatel2361]

Thank you so much sir ❤️

[@solutionpharmacy]

My pleasure

[@mohdsamad70]

Thanks sir God bless you

[@solutionpharmacy]

Thank you. God bless you too

[@SUBHASHKUMAR-cm8zj]

Thanku so much sir🙏

[@solutionpharmacy]

Mu pleasure