Apoptosis: Pathology Hindi Lectures

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𝐒𝐮𝐛𝐬𝐜𝐫𝐢𝐛𝐞 𝗙𝐨𝐫 𝗠𝐨𝐫𝐞 𝗜𝐧𝐟𝐨𝐫𝐦𝐚𝐭𝐢𝐨𝐧 𝐨𝐧 𝗛𝐞𝐚𝐥𝐭𝐡 👩‍⚕‍ 𝐚𝐧𝐝 𝗠𝐞𝐝𝐢𝐜𝐢𝐧𝐞💉🩺💊
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Apoptosis-
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Apoptosis is a highly regulated process of programmed cell death that plays a vital role in maintaining cellular homeostasis and development. Unlike necrosis, which is a form of uncontrolled cell death leading to inflammation, apoptosis is a controlled, orderly process that eliminates damaged, unneeded, or potentially harmful cells without causing inflammation.
This process is essential for normal tissue development, immune function, and the removal of cells with DNA damage that could lead to cancer. Key features of apoptosis include cell shrinkage, chromatin condensation, DNA fragmentation, and the formation of apoptotic bodies, which are then engulfed by phagocytes, preventing the release of harmful cellular contents into the surrounding tissue.
Apoptosis is regulated by a complex interplay of pro-apoptotic and anti-apoptotic proteins, such as the Bcl-2 family, and is triggered via intrinsic (mitochondrial) or extrinsic (death receptor) pathways.
Dysregulation of apoptosis is implicated in a variety of diseases, including cancer, autoimmune disorders, and neurodegenerative diseases, making it a critical target for therapeutic interventions. 🧫🔬✨
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