ASCO 2024: Impact of Latino Ethnicity on Gut Microbiome in mRCC Regina Barragan-Carillo, Phd

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📺 Description:
Welcome to our latest video from the ASCO 2024 conference! In this presentation, Dr. Regina Barragan-Carillo from Cedar Folk Comprehensive Cancer Center discusses her groundbreaking research on the impact of Latino ethnicity on the gut microbiome composition in patients with metastatic renal cell carcinoma.
🔬 Study Highlights:
Objective: To determine how Latino ethnicity affects the gut microbiome composition and its potential impact on clinical outcomes with immune checkpoint inhibitors.
Methods: Prospective collection and analysis of stool samples from 59 patients (27 Latino and 32 non-Latino) using whole metagenome sequencing and NCAMBC analysis.
Findings:
Latino patients showed enrichment of 14 bacterial species, including Roseburia and Eubacterium rectale, which are linked to better outcomes with immune checkpoint inhibition.
Non-Latino patients did not show enrichment of these beneficial species but had a higher presence of Methylobacterium species, which may negatively impact patient outcomes.
Conclusion: Significant differences in gut microbiome composition exist between Latino and non-Latino patients, warranting further research to understand their clinical implications.
🔗 Watch now to explore the full findings and their potential impact on treatment strategies for metastatic renal cell carcinoma. Don't forget to like, share, and subscribe for more updates from ASCO 2024!
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