Blood, Part 1 - True Blood: Crash Course Anatomy & Physiology #29

[@crashcourse]

Pssst... we made flashcards to help you review the content in this episode! Find them on the free Crash Course App! Download it here for Apple Devices: apple.co/3d4eyZo Download it here for Android Devices: bit.ly/2SrDulJ

[@yesicahernandez5846]

Passed my first anatomy class, and now you're making life easier for A&P II. We appreciate you Hank! (and team)

[@nicktekula4928]

Honestly the best page on youtube for all students around the country. And the world for the matter

[@somaliyahh]

Nick T world*.

[@toba6919]

JUP! watching from Holland and probibly saved me from a 3 (F)

[@toniaa-y3559]

I'm in West Africa and this is the only reason why I am not lost in class

[@thousandsummersSOL]

Yup, I'm in Thailand. Crash course has saved me in soooo much.

[@yashasvipurohit6910]

India here...this awesome channel has spread far n wide

[@crimbleland]

Coming back to thank Hank years later. I now work in healthcare and so much of my basic knowledge I’ve learned because of this crash course. Thanks Hank!

[@pereiramariana35]

my mother was rh negative and i was her second child with rh positive, they didnt know until i was born and i had to have blood transfusions as a new born, im so glad this was so well explained, i myself had a hard time understanding and explaining this to people, you guys are the best :3 love from a positive, who still doesnt know her blood type other than it being rh positive

[@iwanebbing4944]

***** why suing...? You don't know her (i assume she's a she) age. The prevention of giving anti-RhD to RhD negative mothers with RhD positive baby's is not that old...

[@skizzler1232]

Cut appears* Bacteria pops up: are you ready to die you cell?!? Platelete: Hold my coagulation factor T-cell: am I late to the party??

[@aaronhughes1815]

Passed my first anatomy class with the help of these videos and I’m currently crushing A&P II. If you’re struggling just keep watching crash course!

[@blackmesa232323]

Watching this is a bloody good time. Hank almost red my mind.

[@kitsunekyubino9345]

blackmesa232323 You should go to the _pun_ itentiery.

[@UzumakiNaruto-ez8jc]

blackmesa232323 Didn't I tell you puns run in my *blood*. Be *A positive* part of the pun community and tell the others I'm the king, also tell them not to *B negative* about the new blood dynasty. Failure doesn't run through my *veins*. Where the *bloody* hell are my pun fans? You *aorta* be a fan too.

[@blackmesa232323]

Uzumaki Naruto claps.

[@guyshepard9658]

Puns aren't funny your efforts are in vein.

[@UzumakiNaruto-ez8jc]

Guy Shepard You don't have the heart to continue.

[@heathercarter1297]

Just wanted to say thank you for your videos! I started watching your videos in 2015 when taking prereqs for my RN. Now I am graduating next week! You've helped alot with concepts.

[@nasrinn812]

Crash course is the best channel on KZbin for students like me. They really make things easier to understand and thank you 😊

[@horiadinu8895]

I rather pay double my tuition to this guy and his family rather than my professor.. He's getting me through Nursing school, this man needs raise my word

[@alyssawinters6632]

You know you're too deep into crash course when Hank starts getting more attractive as the semester goes one.

[@whatsinaname7289]

1:50 "... a part of you that is literally irreplaceable!" *goosebumps* JUST AMAZING INTRO!!

[@TheCalm25]

I watch every single one of Crash Course's videos, and have for a couple years now. I want to say how absolutely expertly these series' are done. I would never, ever want to listen to anyone tell me about the things I learn on Crash Course. But the hosts of each of the series' have such a critical sense of not sounding arrogant nor condescending. I don't know how the group got together, but it's one of the very rare instances in human kind's history which will remain mysterious as far as how such a truly extraordinary group of people (each absolutely extraordinary and forward thinking in their own personal way, and through their own individual lives) found each other, chose to each make a go of this, and came together in such a cohesive, consistently unique, genuine, and somehow entertainingly knowledgeable way.

[@thelinsey09]

I may be 4 years late saying this... but my curiosity about my low white blood cell count lead me to your videos. Your explanations and visuals really help me understand everything. Thank you so much.

[@MarissaLaipsker]

Thanks for helping me and all of my fellow nursing students pass A&P

[@racheljones7339]

CRASH COURSE YOU ARE A SERIOUS LIFE SAVER!! This channel makes anatomy interesting, easy to understand and even fun to learn. Thank you so much, this helps so much in my anatomy class.

[@ericacuevas2301]

How did you make this so easy? We've been going over this for weeks and it all makes sense now. THANK YOU! When I'm a pharmacist and not eating ramen I will support crash course forever

[@meganduckett4372]

This channel helps me so much with my anatomy and physiology tests. Hank goes over a lot of key points that my instructor did, and he explains it a little better to be honest.

[@Bravedom]

I didn't think I'd learn much because I usually get lost with all the words in biology. But this is actually very well taught. Thank you team Crash Course

[@Daywalker777r]

the human body is like one awesome team with a terrible captain at least for me

[@lycheemyusic]

LOL tru

[@moyopengu7021]

lol

[@ricchburglar]

here take my money 💰x300

[@atiquakhan3218]

Your profile is the expression for this

[@angelofhope7778]

This channel has gotten me 87% on my anatomy physiology exams. Thank you so so much crash course!! My number 1 study tool!

[@NathanAndRose]

Interesting fact: while the AB and Rhesus blood groups are the most common blood types for consideration with blood transfusions, there are actually dozens of different blood type groups, that all measure different things. For example, an individual can be AB, D positive, and at the same time M and N positive (MNS system), K positive (Kell system), Le^a or Le^b negative (Lewis system), and so on. ...It took me forever to memorize all of these in school :/ haha -Nathan

[@FrozakRL]

Nathan Hutchcraft thanks Nathan haha found this interesting even though I'm commenting late :) hope your doing well

[@shivanishastri4285]

Nathan Hutchcraft me too, we were tested on this with so much more! Was this in med school?

[@GoArgos2001]

Crash course is the best channel, if not one of one ! 😮

[@palashgupta3521]

Just one word AWESOME...AWESOME...AWESOME... Plz make videos for Physics and Chemistry as well... Thanks a lot TEAM CRASH COURSE...

[@hannahjackson6860]

You are the reason I have a 99% in my anatomy& physiology class right now. Thank you so much for your videos!

[@maryannvictoria4750]

Totalmente impactada con la calidad de la informacion, la animacion y la accesibilidad. Gracias a todas las personas que hacen esto posible.

[@mjay3514]

I am officially a fan ... You've acquired a new subscriber! Thank you for this great information!

[@deemon710]

I've heard the different kind of blood types described several times before but I never quite grasped it until this video with it's very helpful visual aids. Thank you.

[@Vipin-kq5mg]

Thats the cutest WBC I've ever seen! 😁😁😁

[@helixentertainment5890]

This literally summed up the entire 2nd chapter of my textbook for my Anat Phys 2 class.

[@nicolemcdonald9231]

Idk what it is but whenever I get sleepy studying all I have to do is look up a Crashcourse video and it wakes me up and gets me pumped to study some more!

[@lienia83]

This program is so awesome! Has gotten me through some tough concepts in my Ana, Phy, and Chem classes

[@lavishdabas9549]

I visited this channel for the first time and now i can say that it is the *bestest* video i watched today

[@iamjacksusername85]

thank you sooooo much for this video. I was having really hard time understanding blood antigens and their relationship with doning blood. This video saved my bacon!

[@amytesch3880]

Ive never watched all the way through the end of any crash course video where he says who wrote the script and who he consulted so basically this whole time I've thought he was the smartest person on earth and knew a ton of random topics in depth

[@fortuna19]

I love that little reference to Rapsutin when talking about blood clotting. I'm studying the Russian Revolution

[@patriciacruz4105]

Damn. Crash course is much more easier and faster to understand than the 4 hour lectures I have everyday for A&P2.

[@kaboom138]

Did anyone else notice Rasputin at 6:10 when Hank was talking about hemophilia?

[@marinescastellanos6157]

OMG TOTALLY XD

[@jerzymajka9460]

I thought exactly the same thing. Has anyone noticed Rasputin and does someone know what he has in common with hemophilia?

[@marinescastellanos6157]

Jerzy Majka Hey! So Rasputin was a holy man who became associated with the Russian royal family. The tsarevich, Alexei had hemophilia, so Rasputin was called in to heal the prince. It worked, the prince felt better and so from then on Rasputin became a recurring figure in the royal family, which was VERY controversial at the time. XD

[@jerzymajka9460]

Thank you for explanation :)

[@marinescastellanos6157]

Jerzy Majka Al No prob 😋

[@siddharthdasari6598]

To add on, the endothelium is the single layer of squamous endothelial cells that line the interior surface of blood vessels and lymphatic vessels. Thank you for the amazing videos Crash Course! Great way to make use of the time I have on my hands right now.

[@SyedHousein]

The white blood cells carry the Master Sword!

[@ria_artsymw1841]

Doctor Syed believe in your strengths, believe...

[@justinlansford3910]

There can be only one!!

[@bmsenpai8386]

I cracked up when I saw it lmao

[@teedtad2534]

Love videos like this with illustrations! 💵💵🫑💵🫑

[@DuranmanX]

I'm guessing all the dislikes are coming from Crips

[@barrymaguire4535]

***** Come on people, that deserves more thumbs up!

[@WWZenaDo]

***** Ha, ha, Funnneeeee....

[@elstormcaller]

***** Well played

[@markvalebcia8750]

I dont get it Crips???disable people

[@elstormcaller]

Mark Valebcia No, dude, its the name of a gang, their worst enemy are the bloods, geddit? The haters of the Bloods are the Crips?

[@mohammadmokhtarrashedjibla4742]

thank you for being here for us crash course you really made life much easier for us.

[@butterlover7592]

3:16 like the master sword. You can even see the triforce on it.

[@AntonioBrandao]

No we are not replaceable, as someone clearly proves it in this channel.

[@themrkindmanful]

The best man ever and the best show ever...for any student it is a time savier... thus mean MY life savier which end to be ..YOU my real hero. real thanks for you and also for donors thats keep it alive.

[@shivamnrwl]

CrashCourse is really awesome... Especially the animation part.

[@danpham8963]

The Leukocyte with the Master Sword lol

[@christinevakas92]

Ah, I'm at the end of my course - thank you so much for all these KZbins. You and your team have made studying a pleasure, actually had many laughs, and learned so much.

[@iLov3makeupx]

Why am I paying thousands of dollars for a college course when KZbin teaches better..

[@Boognish2784]

I completely love all of these A&P videos!!! They are really helping me and they are so entertaining!

[@MelissaFlaquer]

8:50 actually the antibodies from the mother attack the baby, not the other way around, in most of the cases. To answer the obvious question of why on the Rh group matters in the case of mother to fetus blood contact it is because the antibodies against ABO antigens do not cross the placenta but Rh antibodies do.

[@AmandaLovesOldFords]

I scrolled *so far* to find this comment!

[@Sa.reigh_]

You are the BEST, you r so GOOD🤞🏆and know how to simply things and make it interesting!!!

[@probablyapossum]

Did that white blood cell have a master sword? I HAVE MASTER SWORDS IN MY BLOOD

[@smooshfanultra]

+HeroHeart14z Actually, white blood cells use magic to attack, you idiot.

[@PsychoDiesel48]

+XXX_ “SANIC” _XX NO ONE, FUCKS . . . WITH THE WHITE MAGE! XD

[@smooshfanultra]

Diesel Marcus What's wrong with black mage? You racist.

[@PsychoDiesel48]

XXX_ _XX it was a quote chill XD

[@smooshfanultra]

Diesel Marcus That's sexist.

[@sitihaurakhairani1121]

definitely my hero for mention true blood haha! such a nice page for learning anatomy and physiology

[@rohithr3072]

Don't read this you have got a lot of studying to do...

[@mamamia_144]

Hank! is back! :) so happy!!!!!!!

[@anastaciafrizzell4885]

Lol that leukocyte was holding a master sword 🗡 😂😍

[@helloshanaynay]

This series has been so helpful to my summer class at Rutgers! Thank you!

[@alex-ux3zl]

+Shannsy 95 kik?

[@nordicrain]

5:07 anone anone

[@sammisweeti26]

This page saves my butt every week before my exams (i'm in an accelerated A and P program this summer and I'd flunk without this page). Thank you!!

[@Sproklye]

is that rasputin in 6:14?

[@lilmona1998]

HE TALKS SO FAST! I LOVE IT

[@JohnSF93]

O- here. been giving blood since I turned 18

[@isabelgallegos6294]

I just love all of these videos! Very informative. Very helpful and well explained. Love it

[@Laske_smash]

I like the fact that the leukocytes has the master sword from The legend of Zelda series

[@crisharrell]

This is bloody awesome as usual. Thanks Crash Course!!! A great big 👍👍’s up!!!!!

[@whisper-hc5vx]

When you’re watching in March 2020 where blood drives are shut down because of the coronavirus

[@daylight1440]

i love these vids so much but I just wish hank would speak a litttttle slower. I always have to watch at 0.75x speed to really grasp the concepts. anyway, will always be a Crash Course supporter!

[@sameerathreya9253]

"The property of Hank!" Hah!

[@arnoldpaulssali5622]

if in Uganda we had such lecturers I would no longer be a late comer and I will understand topics in just minutes. anyway u r good at this thing

[@QUICKFACTS247]

"its just a body" but if you know deeply how the system work.... truly God has put so much effort ❣️🥺

[@valiantothello6709]

Very informative. I love the little Rasputin figure shown at 6:15, nice historical tie into Hemophilia ;)

[@Bankstercide]

"Your blood is the one component of your body that we haven't figured out how to reproduce synthesize or imitate." That's great. It might be more impressive once we've got a better handle on Immunology.

[@nyx5939]

I think he was talking about the brain there 😂

[@themuffindragon]

I finally understand blood types! That really wasn't all that complicated and im surprised it took me till age 21 to finally get it.

[@caribbeanqt16]

I like crash course but I think the host speaks too fast. I'm a slow learner so the rapid speaking kind of confuses me. Other than that, I really do appreciate this crash course :-D

[@matthewhardwick365]

Playback speed 0.75? Makes Hank sound like he was dropped as a child tho.

[@robinclarke8736]

Just slow the speed down easy fix, also try professor dave explains!

[@gegogir2]

nuestro profesor nos pone estos videos y la verdad aunque no los entienda son muy geniales te doy like :D

[@sierraslaugh6071]

Hanks hair tho

[@FrozenSoulz]

This is way better than anatomy class

[@__RD14533]

Brawndo - Its got what plants crave. Its got electrolytes!

[@ChrisThomasBone]

OwenBruch22 Water's what they put in toilets and I ain't never seen a plant grow out of a toilet!

[@SusanWojcucki]

Electrolytes are just any material that ionizes when dissolved in an ionizing solution (like water)

[@bobhope4288]

SubscribeToSyndicate You think Einstein walked around thinking everyone was a bunch of dumb-shits? Now you know why he built that bomb.

[@SusanWojcucki]

Bob Hope What?

[@__RD14533]

SubscribeToSyndicate They are all quotes from Idiocracy, it's a movie.

[@yakumofujii886]

I'm not sure why but out of all the Bio Crash Course videos this one squigged me out the most. I don't think I have a blood phobia but I do have a needle one.

[@draconianking]

O- Master Race reporting in

[@cortster12]

Michael Spencer Until you need a transfusion, and then you wish you were AB+.

[@thecynic807]

Where did you get this master race shit from

[@yeahoh2222]

*yeet in*

[@r.m.a4615]

Thank you . You are making things easier for students and teachers too .

[@99thTuesday]

Was that Rasputin over Hank's Shoulder?

[@rileydermanuelian7307]

Four years too late, but the reason is because the Romanov family hired Rasputin, a holy man, to treat their son Alexei's (the heir of the throne of the Russian Empire) hemophilia. It worked, surprisingly. No one knows what he did exactly (he kept it secret because he wanted a reason to stay close to the family), but it is suspected that he removed something that was making him more ill (can't remember what) from his environment.

[@NinjaDemon2481]

Im form México I’m learning speak in English when I see your video my face says omg you speak very fast and need put video in velocity in 0.75. Also I’m PT I’m student thanks for video.

[@Tomyb15]

I've always been bothered by the concept of blood types. What are their real purpose? Because it seems that it only serves to identify foreign red blood cells and destroy them, but what practical purpose does it have? If I being O type receive B type, there is an immune response towards that foreign blood which is harmful to my body. But obviously nature wasn't thinking about blood transfusions when blood types evolved, so maybe if a little of foreign blood enters my body then the reaction isn't harmful (although I don't know in which scenario would this happen). But how would this be useful? I mean that having foreign red blood cells wouldn't be harmful, foreign bacteria and other pathogens would be, but those have their own antigens. So then what? Also it would seem that this system works towards other humans' blood only, since an O type has antibodies for A and B antigens, which would only be present on other people. And having the antigens certainly isn't necessary for our immune system to recognize our red blood cells since O type people live just fine. A final question would be how is it not a problem to transfuse O type blood. The blood contains antibodies for either A or B, so if either of them receive them, those antibodies will attack their red blood cells and should produce an immune response. So what's the deal? Does the immune response not happen or is O type blood always filtered of these antibodies?

[@kimfischer7725]

I may be too tired to understand most of what you are asking, but the last question is easy. Type O can donate to A and B because type O lacks any antigens. Antibodies are only present in the serum or plasma and most donations are packed red blood cells. Rarely is whole blood transfused. So in this instance you are only concerned with the antibodies of the recipient vs the antigens of the donor. Type A has B antibodies and Type B has A antibodies but it doesn't matter because there are no antigens on the surface of those red blood cells to react with those antibodies. Same reason type AB is the universal recipient. Since they have A and B antigens, they have NO antibodies, so they have nothing to attack antigens on the surfaces of any blood cell type.

[@Tomyb15]

Kim Bishop oh so most of the transfusions done are red cells transfusions. That makes sense because it gets rid of the antibodies problem. Thank you. The rest of my questions were a bit more abstract because they refer to the evolutionary advantage of having different blood types. I've been thinking about it and it may be because it may provide more genetic diversity that could help with diseases, since if a blood type is weaker to a disease, not everyone would be at risk. The problems with transfusions would be more of a side effect. I don't know. If later you can read it again and possibly understand what I said and give me your thoughts, I would greatly appreciate it. :)

[@iwanebbing4944]

Kim Bishop Don't forget the Fy(a-b-) in Malaria aswell :-)

[@chillsahoy2640]

Ciroluiro From my non-specialist understanding, the blood types are just a chance consequence of the antigen-antibody system. We evolved antigens and antibodies capable of detecting non-native antigens as a way of protecting ourselves from foreign bodies. Once that system was in place, it continued to evolve and diversify into many different kinds of antigens and antibody responses. So it's not so much that blood types evolved as a specific trait, but when we evolved antibodies, some of them happened to be specifically for blood cells, and as a consequence of that we got different blood types.

[@kimfischer7725]

***** Yes. I am a college instructor for the Medical Laboratory Technician program.

[@sushis7896]

I haven't seen any comments on the Buffy coat at 3:09 ! BUFFY! Are there no Buffy the Vampire Slayer fans in here? There's Buffy in my blood!!! That's so fantabulous! xD

[@headpump]

"now you're bleeding all over your breakfast.."

[@bumbuleetaaja]

I was told in my biology class that universal recipient and universal donor have no meaning in the present as cases when different type of blood is transfused are very rare nowadays. But guess these terms might help to understand the whole concept better?

[@finnmurtons8727]

Hataraku Saibou OVA 1

[@Abominatrix650]

Red Blood Cell-chan - the only waifu who will ever truly be in your heart!

[@kanoaisgermanzgaming2044]

*Hank thanks for information, btw makingvthese videos actually help me in my studies*

[@zarnainsrequiem4677]

Whos here at 2019?

[@rachellanglois5223]

yassss

[@archeryskills5435]

Meeeee

[@InterstellarArt]

Best science video You are totally best on KZbin

[@ThatAnnoyingBird]

FIRST

[@crashcourse]

mistergamer9892 Achievement unlocked. -Nicole

[@lordspoice5192]

CrashCourse neat

[@dismaldice3045]

amc amazing

[@shaterproofblosm]

CrashCourse You guys make me so happy :D}-< my whole experience since i found you has been and will forever be achievement unlocked per morning coffee green brothers learning spectacular bonanza coffee sesh :p 2 coffee's for importance. i don't drink 2 coffee's though, i don't think that would go down to well, more like anxious mass construction or something i donno. Either way thanks for helping make this world an astonishingly awesome place to human it up :p

[@MijnAfspeellijst1234]

mistergamer9892 "First" to bleed to death.... no?...... to much salt?

[@matthewburress1]

Watching at .5 speed to increase focus and retention, but I am laughing so hard because it makes Hank sound like the worlds smartest drunk.

[@nmmeswey3584]

LAST!!!11!!

[@xxbeatuupzz]

Anyone else's mind blow when he said blood was a type of connective tissue?

[@lisabanks1015]

Hank said "flavor" when he was referring to blood type...HA!

[@Varaten]

Thanks Crash Course for doing these videos, I like all you guys videos!