Cannabis for Inflammatory Bowel Disease (IBD)

[@NutritionFactsOrg]

For all of the videos on cannabis, see: nutritionfacts.org/topics/marijuana/. -NF Team

[@Kiyarose3999]

www.leafscience.com/2017/03/17/the-endocannabinoid-system-a-beginners-guide/

[@Permaculturemama]

this study needs to be done with edibles. they could more easily hide the placebo, as well, it would have a more direct effect on the gut. I have taken edibles to calm ibs symptoms and relax a spastic gut response.

[@SteveJohnson007]

This needs to be upvoted for visibility. I don't know how we promote a better study idea, but this is good. I bet we could time-release edibles too, plus you could do something fancy like having 3 groups, 1 control, and a high and a low dose. I love this.

[@cainen6355]

I agree. It is highly likely that the negative long term effects were actually from smoking it. I highly doubt that any normally cooked plant would have such a negative effect on inflammation.

[@Japanimepop]

exactly. I'm 80% sure it's the impacts of the smoke itself that's causing the problem, not the cannabis. Seeing this method of ingestion repeatedly used in studies is very frustrating. It's like giving test subjects a fork to eat soup with so they can show the soup has no health benefits. And most of the nutrition was in the broth.

[@Pyriphlegeton]

Why would this make it easier to hide whether you're taking the placebo? Edibles would still be psychoactive which would make it obvious that you hadn't taken the placebo.

[@victoriajankowski1197]

@@Pyriphlegeton Generally the phycoactive effects are blunted by edibles, making harder to determine if you are getting an actual dose or just a great brownie, especially is its a controlled dose.

[@remy7663]

Dr Greger: UNTILLLL.... ME: NOW! Dr Greger: Two thousand thirteen ME: 😞

[@80slimshadys]

Lol

[@clarksmith6850]

Ironically, the information is SO when, not at all now. Google kanah bosum. It's a Superfood, that can also be smoked, but eat it.

[@rizzen0248]

I have crohns and I can tell you for an absolute fact if I'm throwing up and getting cramping pains they go away but not completely. If you have crohns and its really bad what helped me the most was remicade/infliximab which is an IV in the arm every 4 weeks for 2 hours. Marijauana DOES NOT stop the disease from continuing it doesn't put you into remission to where you aren't sick anymore but it does help the symptoms a lot.

[@mammabear2183]

I wonder if the method of use could be a factor. In other words, maybe eating it or taking it as a tincture would have a different outcome than smoking it. Smoking it introduces other impurities.

[@dieselphiend]

It's absolutely a factor. Smoking cannabis does almost nothing for things like IBD. Where as eating it cures it EASILY.

[@-Kerstin]

@@dieselphiend Source needed.

[@dieselphiend]

@@-Kerstin You expect the mainstream medical establishment to advocate for cannabis in any fashion? How silly of you. They will never provide accurate research for a plant that people can grow in their closets and backyards, EVER. It would take tens of billions of dollars from their bottom line. Regardless, this is all proven. What is it you want literature for? The anti-inflammatory properties of cannabis? Easy. Because that what IBD is, and inflammation disease, and cannabis is one of the most powerful anti-inflammatories you can put in your body. I cured my own bowel disease with it. I still have to use it occasionally to keep all of my symptoms at bay. If I don't have it..MISERY. I have acid reflux disorder, which is essentially eating a hole in my chest. It cures it. I had IBS, and celiac disease. It cured them both. But it's a maintenance thing. You can't ever completely stop taking the cannabis. Its for life.

[@chiyerano]

@@dieselphiend If you have to keep taking cannabis to keep the symptoms of your conditions at bay, then your conditions aren't really cured, are they? Sounds like you are just managing your conditions or relieving the pain they cause which is fine but I wouldn't say they are cured.

[@jimijackson]

Use a dry herb vape. No combustion

[@ChuckBoomBuck]

i smoke weed every day and my bowels feel great!

[@ByrdNick]

“Thirteen patients were included” in that first study? Just 21 in one of the subsequent studies. That’s nowhere near the statistical power one would need to test for a difference (unless each patient had lots of records taken over time). I wish these details were acknowledged and discussed in the videos. When they aren’t it makes me wonder if results are cherry-picked to support a particular narrative or video script.

[@lincolnmarkman]

Dr Greger did it, he referenced The Toys and Smoke Two Joints! I smoked two joints before I smoked two joints and then I smoked two more.

[@christopherstein2024]

Hard work good, and hard work right, but first take care of health.

[@victoriajankowski1197]

I had a friend who spent most of his life in pain and used for that pain, and he pointed out that it didn't cause him to have less, pain, just to care less about it, also while pain relief is great if that relief causes you to do things that result in more damage because you essentially cant feel what you are doing that might help explain the increase of disease progression. If you have a broken leg and you get great painkillers so you are walking around on it before it is healed, it will never heal, I understand in some diseases that is a less apt comparison but it does need consideration.

[@fieldlab4]

Greger is not making many new friends with this series! 😄

[@thomastoadally]

Not everyone uses cannabis?

[@davidgeorge7443]

Maybe Cannabis use lead to an increase in poor eating habits - the "munchies". Perhaps explaining the eventual worsening of symptoms?

[@Test7017]

I give plenty of animals cannabis theye all get healthier better hair better appetite eat more grass

[@yan-G]

@@Test7017 eating cannabis doesn't get you high unless cooked. Also did you even see animals order mc donalds

[@Test7017]

@@theinfiniterick6937 thc is better in certain ways. Full weed is best don't listen to big pharma

[@Test7017]

@@yan-G decarboxalation 👍

[@Fearzero]

@@yan-G It definitely does get you high even if not cooked.

[@stanleyniezrecki2469]

These are all several years old articles. Dr G needs to focus more on new science.

[@danoneill2846]

good luck he wants you to eat GMO soy

[@FireAwayProductions]

Another video where I find myself saying "Hm, that's fascinating" at the end. Great work!

[@carmadefries3729]

Cannabis is why my secondary progressive MS went away. I still have lesions, but they're all shrinking. Whole foods vegan allowed me to become stronger, lose weight... I'm 100% a green lover. 🌱💪🏽💚

[@carmadefries3729]

Oh, and my Crohn's is gone, zero evidence. So, there's that also.

[@carmadefries3729]

I should mention, I went whole foods vegan before Crohn's disappeared. I credit diet choices for Crohn's disappearing. Daily toker for over 15 years, MRI improvement for 12. Whole foods vegan for 4 years, no Crohn's for 2.

[@piberry2419]

As someone with severe Crohn's, I strongly believe that the increase in surgery rates is correlation not cause. People will generally only seek out medicinal cannabis if their symptoms are severe and other ways of relieving pain have not worked. There could also be a factor at play that those on cannabis are less likely to seek other treatment, but I suspect the former influences the correlation, not the latter.

[@1000wastedwords]

I'd be curious to see this done with cbd gummies. It would be easy to create a placebo, especially since the users shouldn't be expecting the effects of thc.

[@ShukusatsuDirk]

CBD might help for IBD, and double-blind placebo controlled studies would be possible - right?

[@freedomdividendnews5042]

or they can do edibles and compare it to chamomile or something

[@GehresWeed]

Doctors prescribed steroids for my Mesenteric Panniculitus an inflammatory malady and they were killing me. I switched to CBD a few years back. CBC is just as affective if not more at reducing inflammation than steroids but with no side affects that I could notice.

[@GehresWeed]

Opps CBD is just as affective

[@yoyoyooo4735]

How do you fake a joined? Canabis has such a unique smell and probably taste?

[@naftalibendavid]

Good job on the methodological problems.

[@AhimsaWitch]

Dr. Earlywine, so cool to see you here, thank you for the years of information in your Ask Dr. Mitch segment in High Times Magazine and your fantastic book Understanding Marijuana. Curious if you regularly watch this channel, do you adhere to a plant-based diet?

[@naftalibendavid]

@@AhimsaWitch My pleasure. Nice to see how mainstream the plant has become!

[@RandyFasnacht]

As a pharmacist I'd like to thank you for the science and separating out the "politics of pot". Well done!

[@allencrider]

Cannabis for pleasure. That's not a bad thing. Really.

[@outrightmed]

That's a huge leap from liver fibrosis to worse outcome in Crohn's disease.

[@iliangeng47]

why you say this in relation to ulcerative colitis

[@iliangeng47]

why you say this in relation to ulcerative colitis

[@iliangeng47]

why you say this in relation to ulcerative colitis

[@iliangeng47]

why you say this in relation to ulcerative colitis

[@iliangeng47]

why you say this in relation to ulcerative colitis

[@Mattchu.the.Pikachu]

I'm a chronic disease patient and you said the study gave them a third of a pound of weed. I argue the study may have had different outcomes if the patients used as much as I have. Being solely on weed and needing no other medication. They gave them basically 1.5 grams per day. But they actually should be having closer to 2.0 to 2.5 grams per day. Weed does have a placebo drug. They could give the patients cbd weed because it looks like thc weed. It would satisfy the placebo effect because it would relax them without the high. Or the thc medicine.

[@erikdavis3296]

It’s unfortunate that prolonged Cannabis use with IBD patients leads to 5x higher chance of requiring surgery. I’ve been using it to help with my Chrons and it does relieve pain significantly, however might need to stop now.

[@gardenfermentbrew527]

OR... Cannabis caused the munchies? Eating solids during a flare gives me nightmare pain - guessing it's possible that pain might signal damage being done by those solids passing thru inflamed mucosa? No way I'd take tincture if cannabis might cause me to stray from my liquid diet! Have they developed a strain that removes munchies? If yes, I'd certainly try that tincture.

[@aprilracine]

The first time I ever had marijuana (25) my side effect was that I could not get off of the toilet 🚽. Previously I had been complaining about chronic constipation. After half a joint I was 5lbs lighter. I only weighed 102lbs at the time. I didn’t have any serene feelings or laughter or jolly good time. I thought I had just smoked the mother of all laxatives. It scared the shit out of my so I stayed awake until the age of 42. I’m currently writing this from the toilet… Food for thought 💭

[@badmamajamasj]

Indica, sativa or hybrid which strain is best for pain

[@milenadeltorto7158]

Good to know. Could you provide analysis of mega doses of vitamin d3? And also the Dr. Coimbra protocol (MS patients claim cured). Thanks.

[@JessiEdmunds]

With patients who had worsened prognosis after chronic use of cannabis - did their symptoms of pain decrease so they started eating more foods that tasted good but aggravated the disease?

[@j3licat]

My thoughts exactly.

[@FASTPAINTSHOP]

Most likely

[@airtitimes]

Or a better hypothesis “some cannabis strains cause more munchies than others, and munchies make people over eat ergo IBD and Crohn’s patients may get worse depending on the strain they consume “

[@aquie4d999]

Might be the munchies that affected what they eat and how much they eat. So likely eating more process foods and affecting as we know the course of the disease through disruption of the microbiome. It could be, too, the simple fact that smoking leads to inflammation. So more inflammation added. But activating, more, the endocannabinoid system through other means, like cold pressed oils or something less inflammatory, could aid people in crises to bear better with their symptoms. Chrons and colitis are debilitating diseases friends. Please don't think it as an excuse to closer the affairs of legalizing pot. It think it definitely can help, but not through the smoking it way. It's an herb after all, and they usually are healing.

[@powderandpaint14]

It could also be that if the cannabis helped with their pain they were able to eat a wider variety of foods and unfortunately that led to more information. I wonder if they did a study where people were on a recommended diet for IBD which they stuck to while taking the cannabis whether results would be any different.

[@aquie4d999]

@@powderandpaint14 me too, that would be cool to know

[@WhiteKitta]

well, we should all know that feeling better isn't actually being better...

[@powderandpaint14]

But feeling better can improve someone's quality of life considerably.

[@WhiteKitta]

@@powderandpaint14 the goal should be to actually get better and heal... staying in limbo is good for nothing at the end of the day

[@wearemilesfromnowhere4630]

What really irks me about the majority of these info moments is that the definition of weed has changed so much in recent years and ignored. The potency is one factor, another is the difference in properties of open pollenated vs single sex strains. I call bullshit on these incomplete viewpoints here.

[@Ryansarcade9]

Love the balanced info!

[@UncleJ2058]

Two joints a day? That is a lot of pot. When I smoked, it was typically two or three inhalations on a joint for the whole day.

[@wadepatton2433]

Yes, that's always a big failing point of studies. They tend to assume everyone smokes two joints, like the song. I've never found that to be the actual case in folks who have a life beyond smoking pot-or those that use it therapeutically. Exception for some intractable pain cases-and cannabis gives them mobility without narcotic addiction.

[@kierandavies3716]

Cheers Owen Wilson

[@watermelon1221]

you talk about the numerous benefits of eating beans. does bean flour still retain those benefits? Such as chickpea flour, lentil flour.

[@Wythegoodsense]

Then again which customized brand of marijuana was it? Smoking it was required?

[@spliter227]

Placebo joints? Ewww what was in those?

[@epr3185]

Earned the like at the "Unnnnnnnntill now.."

[@5unshineBear]

hahah so adorable! the pauses too!

[@danoneill2846]

The Better question is >> How are bullets , tazers , jail , pepper spray , clubs , rotten food & beatings , stolen property , broken families , for your health ?? Please work THAT question in . That should be the #1 question .

[@5unshineBear]

Interesting... thanks so much for your input on these studies. Wow i thought cannabis was a good plant. But i don't want to end up having a higher chance of getting on the operating table. EEP

[@1000wastedwords]

Nothing works in a vacuum. All medicines have side effects, even medicinal plants.

[@vascoamaralgrilo]

Thanks!

[@joeamea9721]

It helps and that is what you forgot

[@danoneill2846]

@ 00:47 The excuse Should be asked of the Do gooder / Authoritarian What is your excuse for killing People & not respecting our constitutional Rights . No different than a glass of beer . It's none of your Business ! You start off with The Wrong Question , you will get the wrong answer .

[@louisedolloff836]

What about cannabis as an edible? Does the difference in the administration of the "drug" change the outcome?

[@nicolawalnut]

Or could the cannabis users have gone on longer masking symptoms when the underlying disease was spreading, leading to needing surgery?

[@cedarforest4621]

Can you do a video on pediatrics epilepsy and CBD oil?

[@Rhiakath89]

Well, I've been looking into this some time now, because cannabis just makes my bowl really active and I usually get looser stool immediately after smoking. It gets to the point that even smelling cannabis buds makes me feel bowel movements. I've been smoking for 14 years for short periods of time with some time between each period (2 weeks smoking and a month or 2 in hiatus). I also smoke it with tobacco which makes me wonder if it makes it worse. So these results didn't caught me off guard at all.

[@kychick521]

Maybe it's the tobacco actually stimulating your bowels instead of the weed. Just another possibility.

[@Rhiakath89]

@@kychick521 I thought the same, but that doesn't explain why just smelling the buds mildly makes me want to go to the toilet. Sometimes it's more instantaneous than oatmeal with grounded flaxseeds in it.

[@westonhuffman7908]

Well, I wish I knew how to smoke cannabis.

[@Rhiakath89]

@@westonhuffman7908 you can always eat eddibles. Not everyone can smoke, but we all know how to eat 😅😂

[@paudib8982]

Cannabis plants are too varied to have been used for this study.There is indica and sativa varieties all having varying THC and CBD levels as well as all the different terpines

[@chuckybang]

Its fine as long as you use the same variety for everyone in the non placebo group.

[@kychick521]

Exactly. Way too many variables.

[@chuckybang]

@@kychick521 One variable. The strain. Control that and its not a problem.

[@trudi1962]

Smoking joints? Are we back in the 70s?

[@csndrimiopsis]

Do you cook the herbs or smoking is better😮

[@smudge8882]

I know smoking marijuana can have some of the same issues as cigarettes. I wonder if there would be any associated risk with CBD or edibles? Either way I'm allergic so it doesn't help me

[@5unshineBear]

Good question! The smoke clings on everything too... it's nasty. Edibles sounds like a better alternative... but not sure what the answer is if the science is the same for smoke and edibles. Anyone knows the answer?

[@scottcarlson1898]

Smoking cannabis has many beneficial affects. This method can actually reduce the incidence of lung cancer. It can also be beneficial for many respiratory issues. Dr. Donald Tashkin, UCLA Med School, has been the studying the affects of smoking cannabis for decades. It is the quickest deliver vehicle which can have profound effects on acute medical issues.

[@smudge8882]

@@scottcarlson1898 This video was specifically on how it affects an illness in the digestive tract. It would make sense that taking it orally would be a better option It's also incredibly odd you are referencing a specific person rather than any study. If that doctor has been researching it for decades, show me the evidence - aka studies he's published.

[@chiyerano]

Interesting. Makes me kind of glad I don't use cannabis. Thanks for the info.

[@Saludtotal48]

Was scared for a moment...thank u

[@InvisiMan2006]

LOL. All these weed pushers will never accept that weed isn't a miracle cure for everything.

[@ChaiJung]

Someone should show Mr. Beast

[@5unshineBear]

lol

[@cainen6355]

So if I saw that correctly, these studies were all done on smoking cannabis. If I remember correctly, smoking cannabis is actually worse than normal cigerettes and I actually highly doubt that any edible plant in it's unburned state would make inflammation worse if just consumed as food like in edibles. To me it seems likely that these very negative long term effects are from the smoking process and not from the plant itself. Maybe it would even be easier to mask the placebo group when using edibles instead of smoking the plant.

[@patrickbateman4541]

Smokeless nicotine has been helpful for my colitis! :)

[@Test7017]

Less meat less sugar more unprocessed foods heal it

[@rojocolorado3764]

Smoking? so 1970s

[@lindapb6529]

💜

[@jeanneamato8278]

Covering up symptoms in the long run is never a good thing. Going vegan is the answer

[@clarksmith6850]

Gregor has a bias. Hoping for enlightenment as his position on this and vaccines is not NOW. UNTIL THEN. . .

[@mithrandir491]

Its vegan right, so you guys should be good....it would hardly make any difference.

[@nwbackcountry5327]

What a grumpy meat eater. Why not be kind? Good luck.

[@mithrandir491]

@@nwbackcountry5327 I don't eat meat dude but good to know this community is totally bankrupt on logic and reason.

[@lizzieb7373]

I think it depends on what these people are eating in addition to using the cannabis.. the study is kinda loose as far as that goes.. what kind of diet were people in the study following?

[@nwbackcountry5327]

@@mithrandir491 Well excuse me Mr. spiffy pants. Maybe I should have said eater of animal products.

[@sooooooooDark]

🙄vp will interpret this as "🧐 next thing i stuff into my enema bag will be some weed 🤓🤭"

[@auberjean6873]

Thank you, Dr. Greger, for your research, videos, daily dozen app, translating medical jargon into human speech, and PUTTING IT TO THE TEST! Oh--and SAVING LIVES in the process! A big thank you to the people behind the scenes too!

[@randolphtorres4172]

THANKS4GIVING