Caspases। Honours+ General। BSC CCF SEM1।

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Academic Astra

Academic Astra

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Caspases in Apoptosis:
Definition: Caspases are protease enzymes crucial for programmed cell death (apoptosis).
Activation: Synthesized as inactive precursors (zymogens) and activated by apoptotic signals.
Types:
Initiator caspases (e.g., caspase-8, -9) activate downstream caspases.
Executioner caspases (e.g., caspase-3, -6, -7) dismantle cellular components.
Function: Cleave structural and regulatory proteins, causing DNA fragmentation, membrane blebbing, and cell disassembly.
Significance: Prevents inflammation, removes damaged or cancerous cells, and maintains cellular balance.
#celldeath #caspases #apoptosis #bscccfsystemsem1 #ccfsystem #Initiatorcaspases #Executionercaspases #zymogens #activationpathway #cellbiology #zoology #bschonours #bscgeneral #academicastra #cellbiology

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