Cell cycle regulation, part 1: Introduction

This video introduces proteins involved in cell cycle regulation: cyclins (such as cyclin D, cyclin E), cdks (cyclin-dependent kinases, such as cdk4, cdk6, cdk2), and Rb, and how these proteins are disregulated in human cancers.

[@ivanvetcher]

Thank you so much. My wife has breast cancer and I am learning a lot from watching your videos. We are in the 21st century and there is science behind something other than chop and burn. Please keep making more.

[@user-oo8fd2ov5m]

thanks so much You are awesome man

[@lehu8529]

You are awesome! Absolutely love your videos! As a pathology resident I am interested to learn a bit more about carcinogenesis on a molecular level and your videos are very motivating and you have a very clear and concise way of introducing these topics (which I’ve learned to an extent in med school, but well, of course I quickly forgot about all of the details cause there’s just too much to study)! Anyway, thank you so much for providing this educational resource!

[@SoraKimchi]

Thank u Joe ❤

[@chriscrudele8901]

Great videos. I'm not sure why these don't have more views!

[@JoeDeMasiScience]

Thanks!

[@user-oo8fd2ov5m]

+1

[@phobos_miner4288]

WOW. You just make my day. Excellent videos, perfect level.

[@JD-nh7vb]

These are very good videos.

[@JoeDeMasiScience]

Thanks! Those are very good initials!

[@user-oo8fd2ov5m]

9:55 What are the other signals that could make cell divide other than growth factors?

[@danielking1583]

Hi sir, I’ve been looking at treating lung cancer with pomegranates and it’s ellagitannins recently (I don’t know how much or if you know anything about this treatment)and one thing I’ve noticed is that the levels of cyclin d decreases to arrest the cell cycle in g1. If you know anything about this treatment then can you please notify me on how the cyclin d levels drop relative to this treatment (could be transcriptional/post translational or other.) Furthermore, if possible could you also explain how this treatment would increase p21 and p27 levels. I would be greatly appreciated if you could answer any of these questions, though if you can not then there are no worries, this video was still really informative. Thank you for this video and your time!

[@swear3994]

If I may ask, which textbook are you following?

[@JoeDeMasiScience]

The Immune System by Peter Parham.

[@ammarahchaudhary2820]

Sir speak in simple English You spek in stylish way and maximum words are not clear. Plz give subtitles also.

[@ivanvetcher]

Professor DeMasi is extremely clear. If you looking for something else go look at Hussein Biology.