Connective Tissue: Extracellular Matrix

Today's tutorial covers the basics of connective tissue with specific focus on the extracellular matrix.
Table of Contents: Time Stamps
- Extracellular Matrix Basics 0:24
- Collagen 2:24
- Type One Fibers 4:33
- Type Three Fibers 4:58
- Collagen Synthesis 5:30
- Practice Questions 10:11
- Elastic Fibers 10:18
- Reticular Fibers 12:23
- Ground Substance 13:00
- GAGs + Proteoglycans 14:00
- Adhesive Glycoproteins 15:11
- Summary 16:02

[@wamiqfarooq7401]

You really are a wizard. This 16 min video contains a lot of info. Thank you

[@thehistologywizard5783]

Thank you for the kind words

[@user-ld7tm9id4q]

I love you histology wizard❤️

[@keithwins]

This is fantastic, thank you. Very information dense and thorough. I'm really excited to discover your channel

[@thehistologywizard5783]

Welcome aboard!

[@neillamas8929]

Note to myself: this is a more detailed description of the extracellular matrix (ECM)

[@durmushfam1252]

Thank you so much!This was very helpful!

[@thehistologywizard5783]

Glad it was helpful!

[@reshale22]

Thank you Actually type III collagen is most abundant in keloid scars not type I

[@thehistologywizard5783]

Hi- My research suggests that histologically, hypertrophic and keloid scars both contain abnormal amounts of collagen, but hypertrophic scars consist of mainly type III collagen fibers arranged parallel with the skin surface, while keloids contain disorganized type I and III collagen. Overall, keloids have higher collagenase activity, type III collagen, chondroitin 4 sulphate and glycosaminoglycans than normal scars. Keloids show expression of upregulated type I procollagen and unaltered type III procollagen. These changes result in a markedly elevated type I/III procollagen mRNA ratio compared to that in normal skin.

[@ashwienbaidoesingh5783]

can you give subtitle in dutch

[@rileysmiles]

hi dr. moore!! i found you from the noted anatomist. im nowhere near medical school yet, actually soon to be high school student but im teaching myself this stuff and trying to make sense of it from your guys videos and i was just wondering (and im sorry if this is a dumb question), sometimes its more obvious but can you usually tell what plane these anatomical sections are taken from to get a better mental image of the context in the organ as you get better at knowing anatomy?? like whether its coronal, axial, or sagittal kinda thing. thank you for the videos they are really amazingg

[@thehistologywizard5783]

Hi Riley- Thanks for your kind works. And great feedback, I'll be sure to do that in my future videos.

[@rileysmiles]

@@thehistologywizard5783 thank you so much dr. moore, i have made a goal to watch atleast one of your videos every day and take notes and i am learning well so far!!

[@rename5591]

Can you give a subtitle indonesia

[@thehistologywizard5783]

I'm working on this!

[@tianakazazi7348]

lack of vitamin C causes scorbut, common with sailors in absence of fresh food

[@thehistologywizard5783]

scurvy- yes, also folks with food insecurity or alcohol use disorder or other lack of vitamin C can also get scurvy

[@roblochi8997]

bro she look like Jesus you realy saved me with this 16 min

[@thehistologywizard5783]

Glad to help.

[@SMJ24365]

My exam is tomorrow and I was literally freaking out until found this video, Thank you so much for the amazing, short, precise video🤍🤍

[@thehistologywizard5783]

Glad it helped!