COVID-19 Vaccines: MODERNA | PFIZER/BIONTECH | ASTRAZENECA

Official Ninja Nerd Website: ninjanerd.org
Ninja Nerds!
During this lecture Professor Zach Murphy will be discussing COVID-19 vaccines including Moderna, Pfizer/BioNTech, and Astrazeneca/Oxford.
We are NOT sponsored and/or endorsed by Moderna, Pfizer/BioNTech, or Astrazeneca. We are presenting on RESEARCH and in no way is any of the information provided our own view or opinions.
This will be a lecture packed with the process vaccine developers must go through; which includes a preclinical phase and phases I-III. Including information about OPERATION WARP SPEED and how this has expedited the normally lengthy vaccine process.
We will then discuss how Moderna, Pfizer/BioNTech, and Astrazeneca vaccines work in the human body, preventing the SARS-CoV-2 virus and hopefully, ending this global pandemic.
Finally-- Zach presents on all of the most current data that each of the vaccine companies have released outlining the vaccine procedure and how it will be administered, the vaccine efficacy (as a percentage), optimal storage temperature of the vaccine in order to remain viable, and the number of vaccine units these companies are capable of producing. We hope you enjoy this lecture and be sure to support us below!
IMPORTANT INFO (MUST READ):
One thing to emphasize that wasn’t harped on enough from this lecture is when these vaccines lead to an immunogenic reaction as we described above, which leads to formation of Memory B cells and Memory T cells. This is important because if we are exposed to the virus those memory cells are now primed and able to recognize and mount a powerful immune response against the virus.
LASTLY, one additional point and clarification is when those cytotoxic T cells produce destructive molecules that damage host cells it’s important to realize that those are memory cytotoxic T cells primed by the Vaccine that damage host cells that ARE INFECTED with the SARS-COV-2 virus, NOT CELLS processing the vaccine.
Big Takeaway:
1. Vaccine stimulates antibody production to protect against virus IF INFECTED.
2. Vaccine stimulates development of memory T and B cells to protect against virus IF INFECTED.
References |
Regulatory Affairs Professionals Society (RAPS) COVID-19 Tracker
www.raps.org/news-and-article...
Outline:
00:00 - Intro and Overview
01:00 - Vaccine Development Phases Overview
05:08 - Pre-Clinical Phase
06:32 - Phase I
08:29 - Phase II
12:36 - How the Vaccines Work (Moderna and Pfizer/BionTech)
21:16 - How the Vaccines Work (AstraZeneca/Oxford)
25:33 - Vaccine Data (Moderna)
30:30 - Vaccine Data (Pfizer/BionTech)
35:21 - Vaccine Data (AstraZeneca)
43:02 - Wrap-Up
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#COVID19 #coronavirus #vaccines

[@NinjaNerdOfficial]

Update: Check out the update video regarding the Delta variant! kzbin.info/www/bejne/o6m3goR6YraJoM0 Hi Ninja Nerds! Because this is such a sensitive topic to a lot of viewers we need to make sure everyone is able to read this important disclaimer! -- We are NOT sponsored and/or endorsed by Moderna, Pfizer/BioNTech, or Astrazeneca. We are not suggesting that this company data is the end all be all and that you should receive any of these vaccines. More studies need to be done for sure! We are simply presenting on the RESEARCH performed by these companies so that you may be educated about what we CURRENTLY know about these vaccines and in no way is any of the information provided our own view or opinions. Also for additional information regarding the memory T cells and B cells response to vaccine look in the description box. Thanks everyone

[@beratakn6007]

What about sanovac and Sputnik 5

[@Sachin-wb9bg]

@@beratakn6007 at least study most effective vaccine right now..🙄

[@Energyaddict294]

This guy is soon to become if not already a KZbin star. Almost a million subscribers. Holy moly!!! Get that bagggg Zach!

[@faridabbaspour44]

dear Zach can you make these type of video for vaccines from Russia or china

[@andrabook8758]

can u go over the extreme cold mechanism please

[@NinjaNerdOfficial]

Hey Ninja Nerds, wanted to clarify an additional point in the video for you Immunology Nerds!!! Cytotoxic T cells don’t Directly stimulate B cells to become plasma cells and make antibodies, it's indirectly through those cytokines. Cytotoxic T cells cytokines like IFN's stimulate macrophages increasing expression of MHC II complexes which activate T helper cells which stimulate B cells to turn into Plasma cells and make more antibodies.Wanted to make sure it’s clear how Cytotoxic T cells are indirectly involved in antibody production, even though it's primarily the T helper cells that stimulate B cells to make antibodies.

[@TheScnursetolove]

Thank you for this explanation!

[@snufkinsnufkin2528]

By what mechanism don't the Tcx cells attack the host cells that interacted with the vaccine mRNA?

[@torisimmons9672]

i have no idea what this means. but i cant wait until i take an immunology class and understand this

[@MorpheusTheBro]

@@snufkinsnufkin2528 I have the same question. I don't quite understand why Cytotoxic T cells don't destroy the initial host cells...

[@alexgekh]

@@MorpheusTheBro I'm wondering the same thing, could anyone have any explanation about this mechanism ? because any MHC class I molecule with foreign protein bound to it (like this S spike protein) will be detected by Cytotoxic T cells with their CD8+ receptors and will causes release of various types of enzymes and also by FAS mechanism eventually causing cell death/ Apoptosis mediated cell death. ?

[@dshelby6146]

Maybe now in hindsight in 2023 you can explain all the fatal sight effects that are now almost common knowledge that are now being documented

[@jenniferm6093]

This could possibly be the best lecture I’ve ever heard

[@khinyioo685]

I'm a retired Microbiologist after working 33 years in the National Public Health Laboratory of my country. I wished you'd been there when I was a medical student. Would have made my studying more effective. Love you and your lectures.

[@solar0wind]

@@SwissTravelChannel mRNA is broken down quickly, so errors in a few mRNA molecules aren't really that bad. That's why the enzyme that makes mRNA (RNA polymerase) doesn't even have a good proof reading function, if any at all. The polymerase is like "let's make some more RNA as quickly as possible, so who needs proofreading? If something goes wrong, it doesn't matter anyway." The problem is if mRNA is continuously produced wrongly because a part of the DNA is damaged. That's why the enzymes that replicate DNA for cell division (DNA polymerases) have really good proofreading functions. And there are also enzymes that fix damaged DNA. But sometimes, an error can still happen, especially due to damaging environmental influences. And yes, damaged DNA can cause cancer.

[@sophiasophie7143]

I agree!! I really love his videos with all the explanations!!! 😊

[@lovetosmileclearaligners2301]

Hey, as a pro, what do you think the mechanism of how the astrazeneca vaccine ends it's process is and how the DNA breaks down?

[@armandoc.3150]

@Arthur Ashy Cmon dude, stop being a clown.

[@jennifersequeira7510]

So true! What a great lecturer you must be, if you are in the Fac of Med. Would love to listen to more of your great presentations.

[@user-ym9en6pv9f]

Do the world a favor, venture into academic medicine, become a medical professor. Your lectures would be absolutely brilliant.

[@beckmack1994]

@Sam Yaza This is the unfortunate reality of this corrupt world. thanks for the reminder!

[@rellovkrik]

@Sam Yaza Plus he can't say "interim" correctly. I kid of course as the overall preso was really great.

[@rebeccaday3768]

@Sam Yaza but that's only the case in the US and countries where healthcare is operated on a profit making basis. In the UK our NHS only treats appropriately rather than pushing people to have tests they don't really need (which I know happens in the states due to people who have worked there or lived there coming over here and seeing the difference in the NHS approach). The NHS also provides the most advanced treatments - such as ECMO - to people who are on benefits free. All human life is valuable. If you have a non-profit health-care system, this focusses on truly caring for people's needs and making appropriate decisions which may lead to older people not being subjected to tortuous intensive care treatment beyond a certain level if they develop multiorgan failure. I would love to see the US radically transform their tragically unfair healthcare strategy.

[@sanzioandfam8588]

Seriously! I can't pay attention for crap, but I actually LEARNED something with him!!

[@martyfarrell2465]

@@beckmack1994 may I suggest you go to a local city council meeting. Or County Council meeting? You see there is a all mighty "WIZARD OF OZ" behind all this BS UNITED NATIONS = ICLEI'S= IN VIRTUALLY EVERY SINGLE MAJOR CITY, TOWN, COUNTY AND STATE IN THE REPUBLIC? REMOVAL OF THESE POLITICAL PAWNS OF THESE ENTITIES IS IMPERATIVE TO OUR REPUBLIC! ICLEI = INTERNATIONAL COUNCIL FOR LOCAL ENVIRONMENTAL INITIATIVES

[@bobbylawler2657]

You are an incredible teacher. I could actually understand what you were talking about. Thank you.

[@tresfort7321]

20:17 - do you have a reference for the statement that cells expressing spike from vaccine MRNA do not get taken out by the immune system? I've seen some slides presented by Dr. Sucharit Bhakdi which appear to show tissue destruction in capillaries where spike was expressed. Been a while since this video, I'd be curious to hear an honest update, as well as discussion of the pathologies we've come to see as a result of the vaccine. Interesting that you also note in the beginning that the spike is the most pathogenic part of the virus. I was a big fan of your channel when in a BSN program in Canada, but had to leave school and a career in nursing after refusing these experimental jabs. Honestly, very glad I did so. Also curious to hear your comments on the recent preprint studies re myocarditis from Thailand and University of Basel, Switzerland. They indicate that about 3% of recipients experience troponin elevation. Cheers.

[@davidhowe6905]

I've seen several videos which gloss over what form the immune response takes. I tried to find how mRNA vaccines work from the UK National Health Service website (since there's a blue banner directing you there on many YT videos discussing covid), but failed to find anything helpful (maybe just chose bad search keywords). I sent a request for where to find this information but was told that '...the issue you have raised does not relate to the website'.

[@mahdi4643]

I really love it when he asks something and then he responds I'm glad you asked😂😂😂

[@nolanoland3283]

😂 😂

[@fatemey4312]

Exactly 😂😂🤣

[@shereef3823]

Thank you! Just like a college lecture...101. Big help. God bless you!

[@chrischukwuma6469]

I love it. It gives me that quick laugh

[@kristinaahnemannridgely929]

HA HA HAHAHA🤣😂🤣😂😂🤣😅😆😆😆😅🤣😂🤣😅😆😅

[@hefferonjoe]

No one, and I mean, not anyone, anywhere, works a white board like Zach

[@alwaysv]

Agreed.

[@ryandenslow8225]

I would be much smarter if half my professors could format lectures like this.

[@TheEglene]

He is a white board ninja ;)

[@BillAnt]

This guy from the hood has some street cred with that hat. he-he

[@berrysmith2451]

Why are coments turned offlomnsomeN

[@heinrichwebb6447]

Amazing video and presentation!! Funny how I’m inspired to teach every time I watch your videos 👏🏼

[@XtremelocoB]

Thanks ninja nerd I have been watching your videos since I passed my boards the first time, thanks for explaining this without leaving specific parts out like others to scare people.

[@augustopasquini2327]

Can t believe such lectures are for free. Really guys thank you from the bottom of my heart. Love from Italy :)

[@serfranklin6022]

They get paid by KZbin, being monetized..... A good KZbin video equals good money for its creator

[@armandoc.3150]

@@hansveen7132 You should question everything free or not.........duh.....you've let your skepticism turn into paranoia...

[@armandoc.3150]

@@serfranklin6022 We know....its still free because youtube pays for it not us...if he was on patreon and charging itd be a different story...

[@serfranklin6022]

@@armandoc.3150 I know that it's free for us, I wanted remind you that they get paid by "somebody", and that's the incentive for them to put in the work and time.... It's free for us, but they don't do it for free (and rightfully so), otherwise i'm sure they'd rather spend their time doing something else

[@armandoc.3150]

@@serfranklin6022 Well of course they are paid one way or another even if they dont see it as a job or if they have an employer because there are also donations. However I will say, it being free or time and effort into a video is irrelevant to how successful a video will be. It's completely based on emotion not logic. Also they do work for free here unless you count spending their time as currency or their overhead and in the end it's really not that much and you could possibly have it written off for taxes, depending on your setup. You get what I mean?

[@ethansteele3825]

Zach truly has a special gift for teaching

[@jonathanlyng3442]

I will always be amazed at people who could talk about something while still writing something else on a board without missing a beat. I tend to pause one or the other. and that space management is nuts.

[@s.q4265]

His name is Zach??

[@willdeeny6686]

Ca

[@ritapassmore7788]

VAXX is ☠️ ous. Good luck with that. Anyone that gets one will carry a real virus that will kill us all. Research

[@jonathanlyng3442]

@@ritapassmore7788 I see you haven't done your research. Facebook isn't a news source.

[@remy2968]

If you can teach someone like me all of metabolism in a week you can teach this country about vaccines. You are a legend!!

[@superfriends8336]

every time i think i’m a **little** smart, along comes a guy like this to humble me up real quick. i know nothing. thank you for this valuable information

[@eurekaakerue4649]

❌✅ but he’s not tilling you the whole truth - No mention of the irritant needed namely Flagellin/Flagella 👋🧐 bacteria to get this ball rolling , So Why ____ because it’s not approved in any Vaccines 💉‼️✅ read Up chums or Become a Chump too these BS scientists 👋😡 guinea pigs 🐷 Sorry but it’s true // this VAX soo good not even 2/3rds of theses So called Scientists Have yet to Take it Wonder Why❓❓❓❓❓❓❓❓❓❓❓❓❓❓❓❓❓

[@vonmajor100]

@@eurekaakerue4649 true in many ways. I do not fault him for his presentation. I agree with you it is the other “schtuff”, trying to keep it G-rated, in other words the adjuvants that in many cases become the most dangerous parts of the cocktail. In all to many cases we keep using them under the faulty line of thought because we have always done it this way. Many have caused irreparable harm as a result. To challenge that line of thinking you very likely be accused of promoting sorcery. My daughter most likely was harmed by aluminum adjuvants. They will deny it or dismiss as just part of the collateral damage. We have to live with it for a lifetime. Oh, btw you are never given any warning about it and they all have legal idemity from any damages caused. Translation: you are on your own after that.

[@eurekaakerue4649]

❌vonmajor100 ✅ Yup 👍 all alone 👋😡 the only immunity this Vaxxecution Gives // is immunity From Law suits for (Big P- harm -a) (the GOVERNMENT) ,and ((Rothschild FAUCI &Friends)) ❌

[@superfriends8336]

@@eurekaakerue4649 you’re so cringe please stop

[@barry7608]

Sadly you need a very large quantity of “humble” cos that was BASIC biology without the detail. Glad you “learned” a bit.

[@hekata12]

That passion in which you said activated at 17:51 is truly something else

[@saiyanbro]

It was like a movie. The drama! I love it. LoL

[@joela.4058]

19:08 is comparable in glee

[@JimSpence]

I wish I had an instructor like this in college. A lot of smart people out there. Not a lot of smart people can explain and teach things well

[@daliab8493]

Me too!! And a lot of instructors have terrible handwriting, making it even more stressful to absorb the material in class.

[@nathanbanda4013]

very clear and articulate

[@anitramoore9514]

Truths

[@yahyaraz4617]

Facts!

[@sharkymoon422]

You mean a bs instruction.. A vaccine takes 9-12 years to make and the current injection out there is still at stage1 , it will move to stage 2 January 2023 if it passes 😂😂😂😂.. He has no idea what the vaccine does because it hasn’t been tested for long enough and is irresponsible even talking about it😂😂😂😂

[@baddestjoanna-michellesmit5578]

I totally loved listening to this ! Thank YOU . Much love and peace.

[@meditatetodialtone3792]

You have a great presence, I’d love to have a teacher like you (I’m 40 so unlikely) but you’re a natural at teaching

[@flygirlusa8460]

I am a retired RN , a flight attendant now and I am obsessed with the science behind EVERYTHING Covid and the vaccines!! I feel like my brain has grown😀 and it has new purpose for learning something very interesting and complex, I have 4 legal pads of note and drawings, thanks to you and other u tube virologist and doctors, but the drawings and diagrams are thanks to you, they make me look really smart!!!

[@davidbee3704]

Am curious. So after all your research on vaccines, will you be taking it?

[@ArtDesignHobby]

@@davidbee3704 Yes - they were researching it for whole 3 months - sounds safe ;)

[@davidbee3704]

@@ArtDesignHobby Wow. I'm no medical expert - I'm a professional engineer, and my research tells me not to take it. But each to their own. Happy New Year.

[@ArtDesignHobby]

@@davidbee3704 When I watched how they manipulate covid stats I lost the rest of trust to their vaccine safety tests... :/

[@davidbee3704]

@@peek5548 Yep. 👍. I don't trust the government and media. It's bollocks!

[@joserodriguez-og9zd]

This guy is just amazing. I passed anatomy and microbiology with an A just by watching his videos. Thank you so much!

[@asmrconnections8008]

That is amazing

[@DaivaDarpana]

...but you still did not find out what exactly is happening with produced spikes :) and how willingly they join to ACE2 receptors, settle down in tissues.

[@rafalhaenel4801]

🤣🤣🤣🤣🤣

[@boupitpit4358]

@@DaivaDarpana งง

[@irinagorbarchuk561]

@@DaivaDarpana n bbbnbnbbbbbbbb:n n n) l %l

[@indubitablyilliterate3497]

Thank you, I have been searching for a more in-depth explanation to the vaccines. Your passionate about biology and it shows through your videos. You have my sub.

[@Bee-nk8nk]

I have never loved Biology until i saw this. Thank u.

[@nikkia4950]

I've never had anything explained to me as concisely and directly as this. 10/10

[@clubemprendedore2460]

I cant keep quite, i got cure by doctor ODUDU, i ordered my herbs and received it is due time, i used it as direct, its all in the video.Dr ODUDU, a herbal medicine, has been curing hundreds of HIV/AIDS ,HERPES 1-2, HPV, HEPATITIS B, CANCER,histoplasmosis, Isosporiasis ROSACEA, ALZHEIMER, ALS/MND, MS, FSHD, EDEMA, ERECTILE DYFFUSSION, CROHN'S DISEASE, DEPRESSION, , PARKINSON, LEUKEMIA ETC. patients using natural herbs. He has on countless occasion after curing patients presented lab results both positive and negative, together with the cured person.. HIS WHATSAPP:[phone]

[@nikolamladenoff3516]

Maybe you should enroll at university then lol

[@wilsontexas]

Except a lot of what he said isnt correct.

[@kevincook5671]

lies explained well are still lies. 10 out of 10 is his 'useful idiot' score.

[@_Viking]

Someone should seriously nominate him for a medizine Nobel prize. He make complex medizine understandable for common people!

[@a.s.5280]

these are just the basics when you study medicine or pharmacy, it can go far more deep ;=)

[@surfinmuso37]

if thats not sarcasm u should be very concerned. Only a braindead fool/gullible dunce would accept experimental dna manipulation.

[@sharkymoon422]

/? He knows nothing and isn’t transparent with his explanations.. Vaccines take 9-12 years to approve, 85% fail by year 8?! I didn’t here him mention this😂😂😂😂😂 Fat ugly nerd is his scientific name

[@fidelty2427]

This guy us full of crap. The mRNA can enter the nucleus envelope during cell division when the layer is thin and weak and indirectly incorporate itself into the genome through reverse transcription. You can find this info elsewhere. This guy is not the only one out there. You have to look at all the info and then summarise it. There are scientists (immunologists) who say this virus is fake, that they have rebranded the common cold and flu as covid. They have had 1500 samples of the cases but could not find the virus. They even cross-checked with universities in California who requested a sample of the virus for studies, but the CDC said they don't have any samples. Now they are suing the CDC.

[@spudwesth]

@@fidelty2427 I remember the guy.

[@izwaterloo]

Thank you! Would be very interesting to understand how the second shot (booster) works in the body and why it's different from the first shot?

[@aggie0707]

first is placebo ....

[@S4h4r4s]

I'm glad this gives me a better understanding visually than other videos that are animated.

[@layannaser8613]

The sad part about this very interesting lecture is that the people that need to see this will never see it.

[@mohammednazari9833]

I wish you were wrong, but you nailed it.

[@thecollector5243]

I have watched the whole video and will still not be taking the vaccine - for now. I intend to wait a few years and see how it goes with the people who have taken it. I am totally pro vaccine, however when it comes to SARS-Cov-2, the risk/benefit ratio does not warrant taking a vaccine that has received rushed emergency approval. Especially considering that in the many years of trials, no mRNA vaccines has ever before made to the market for humans. Thst is has received approval in the midst of a crisis, gives rise to legit concerns. I am not against mRNA vaccines in general, if they prove save and effective after long-term studies. Just beause our governments are too incompetent to have developed plans over a 9-months period on how to effectively protect and treat old and sick people and continue to keep everyone in lock-downs, I will not risk my health for what is basically an experiment on a global scale.

[@pamatya]

Nice lecture indeed.. But it does not mean that this lecture is trying to say the vaccines gonna be super duper.. Nooooo. Vaccines may not work at all, or may even have serious side effects still unknown to mankind.

[@pamatya]

@@thecollector5243 Nice lecture indeed.. But it does not mean that this lecture is trying to say the vaccines gonna be super duper.. Nooooo. Vaccines may not work at all, or may even have serious side effects still unknown to mankind.

[@annatanneberger1]

Layan Naser: That is the most arrogant statement to make. "The people who need to see this will never see it." Presumably you mean people who are not as clever as you? You mean people who might wonder about a vaccine that is so safe you have to be shamed into taking it, because it is for the good of society as a whole, "it's not about yourself, but to protect other people," for whom the vaccine presumably does not work, and for a disease so deadly you have to be tested to know if you have it . And why would someone take a vaccine for something that has a 99.9% survival rate?

[@mmsmith1525]

Bro you're the best teacher I've ever had, your clarity is at the top level and I just had to subscribe so I don't miss a moment of your teachings

[@cindyr5056]

Thank you Zack for this excellent lecture! Your are a truly gifted teacher!

[@morganmorrison8775]

Hello how're you doing hope you're safe due to the covid 19 pandemic

[@janak6534]

This video is amazing. The amount of hard work and great explanation is insane. Thank you so much.

[@RIDEON909]

I wish I had a teacher like you when I was in school,I would’ve had more interest.Thank you for helping me understand the whole vaccine making process.

[@algore92]

This is such a complete picture of everything I wanted to know and more, and it's relatively easy to understand. Awesome video.

[@geofflee576]

Questions to Ninja Nerd (please): [1] the human cells after having received the mRNA , do they get metabolised, or do they get destructed from vaccine immuno response ? [2] any research on short term / long term effect of lipid nanoparticles ? I couild well be wrong but I heard it has potential to cross Blood brain barrier membrane or this is simplily unfounded "rumors". thanks.

[@julienoel473]

I also would like to hear this response

[@nahimgudfam]

Just get the vaccine.

[@sandrameesala6804]

The lipid covering is basically a lipid bilayer like the cell membrane is for all cells. So it would fuse. Its not the same as a lipid molecule going through like ethanol or nicotine. Then the mRNA gets deposited in say an endothelial cell. Can't leave the cell afterwards. And because it is only one specific message (recipe to make spike protein) then nothing more will happen.

[@julienoel473]

@@sandrameesala6804 ok thanks for that clarification! Also since the coronavirus is highly morphable and is currently bypassing the vaxt’s ADE based immunity resulting in the stronger variants and has animal reservoirs, then why aren’t we focusing our treatment at the S1 or S2 receptors so that it doesn’t morph past it’s “strongest link” ?

[@jorgelouis709]

@@nahimgudfam What type the mRna type or the claszdic one ?

[@aimanshuhaimi7426]

One of the best explanations I've seen so far. Thanks!

[@surreyian]

I don’t believe anyone who knows about medicine can write so neatly

[@dman5909]

Tell Zach he’s the man

[@IneshKhanal]

Absolutely

[@NinjaNerdOfficial]

You’re the best!!

[@amiysao4343]

absolutely not

[@miltonedwards123]

Zach ,youre the man!

[@misskallitheakherl-pyncke]

Well-explained! Feel like I study the specific field! My Appreciation, Sir.

[@maryjane6346]

The internet has created more impact in our life, financially, socially and otherwise, for the betterment of our lives.

[@maryjane6346]

The Bitcoin market is home to endless financial opportunities, if you are not focused you will get sucked in crowd thinking, but thanks to expert Mrs Tessy for is contribution in the crypto space without her a lot of us will be lost in a day trading.

[@wilsonforks1112]

Bitcoin is fast rising and if you are lucky to have a good broker, then i believe you have absolutely nothing to worry about because you are in for a financial upliftment.

[@michealcliff4994]

@@wilsonforks1112 You are right my friend, a lot of people are ignorant to understand that Bitcoin is the future, in fact, i think is one of the best thing that has ever happened to our generation.

[@michealcliff4994]

Bitcoin is rising like wide fire 🔥

[@sandrajasper2176]

Trading has not been going well with me, I have invested a lot of time and failed, I trade on my own but each time i keep losing money.

[@lizardmilk]

Not sure if I am more impressed by your knowledge or your handwriting skills.

[@COULDbWORSE1]

He writes to small I cant see

[@leandrozuniga5634]

My physiopathology teacher's hand writing look like chicken scratch, I hated him at the beginning, but hey! Just in a couple of weeks I love him a lot, he was as brilliant as this ninja. ☺️

[@barbaraburton6150]

Right?? 🤣🤣

[@bretz9276]

Handwriting

[@kateryna1611]

😂 same

[@T-bag89]

I love your energy! I wish you had been my biology teacher 😂

[@hiraldosternflyer7112]

One of the best lectures I've heard. You are an amazing teacher, and I say that as a teacher of 15 years.

[@bethkatehis5084]

I am in the Moderna Phase 3 Cove Study Trial. I chose to volunteer and participate because I want to help get a vaccine out and I feel compelled to help and contribute to society in regards to this pandemic. This Coronavirus Pandemic 😷 Needs to be something of the past and we need to move forward with our lives. Thank you to all volunteers and participants of all clinical trials and to all doctors and nurses. Thank you for this very well instructed video regards to such a sensitive topic!

[@skinnygumbo2700]

Thank you for volunteering. You are taking a lot of risk by doing this.

[@er5282]

Are you supposed to be disclosing that? Thanks for your effort either way.

[@skinnygumbo2700]

@@er5282 Why should be this disclosure a problem? The only thing that matters is that neither her, nor the scientists know if she got the real vaccine or a placebo.

[@er5282]

@@skinnygumbo2700 I don’t know either way. Perhaps they signed a NDA. I don’t know the rules of being a participant.

[@MrCharlieSurf]

Moderna trials don't finish until October 21 2022! All those that take the shot are in this clinical trial. Even the trial calls the genetic component of this "experimental" Only the really brave or ignorant would sign up for this gene therapy.

[@westfield90]

Really excited for this one. His explanations are always the best.

[@andrewngai8902]

Does the research indicate what will happen to the host cells that are not infected by SARS-COV-2 virus? And can the host cell also be invaded by SARS-COV-2 virus that the virus mRNA co-exist with the vaccine mRNA in the cell?

[@framestomind7548]

I think is due to make a Video of how the natural Antibodies we made from having contracted covid-19 are naturally the best form of protection and that we do not need vaccines on top of our already attained anti/bodies! Can you please bring up this topic so everyone can relax and trust their own immune system now! thanks

[@lisaariottiart]

Yes! ---science loves science tho 🙄

[@framestomind7548]

@@lisaariottiartwhy do you say though!? sounds like you are specifically NOT a scientific person when you write that based on a scientific statement... are you an alarmist voting for Biden's mandatory vaccine of people that already have anti-bodies!? a real Dummy in other words!?

[@cloudoftime]

@@framestomind7548 And now what you just said isn't scientific. Making all of these presumptions that the person has something to do with Biden and is therefore a dummy? Wow.

[@hammerradiology1470]

I love how casual you are with your hat on and blurt out this immense amount of knowledge. Hats off to you :)

[@hotfyraraber]

Are you looking for science or for catwalk !!

[@hammerradiology1470]

@@hotfyraraber it was a compliment, nothing negative :) stay safe and cheerful. ✌

[@jamesflannery-serle3489]

Where is the triple blind testing

[@jdgower1]

I already knew a lot of this stuff, but the way you filled in the holes of what I wasn't 100% on, was really impressive. You are a really good teacher.

[@glennc100]

17:51 Activated! i love this guys passion

[@neffada]

Just got my AZ jab yesterday, no sign effects so far. Great video!! Exactly what I needed to know :)

[@ramaarafat4608]

how is it going? im about to get AZ next week

[@neffada]

@@ramaarafat4608 just got my 2nd jab last week, no side effects too. As I saw people got the side effects after 2nd jab, I was expecting getting fever or headache but gladly I'm feeling fine right now.

[@francescabianchi5733]

Thank you for your lessons and your clear explocations and prounounce... I am italian,but I really can understand what you teach... You can not understand how happy I am,when I follow your lessons!!! Thanks a lot! I will thank uou for all my life!!

[@pr0ph3cy47]

I’ll be getting my vaccine on Neveruary 32nd.

[@laurenespen3035]

I always love your lectures and I recommend them to people all of the time, especially at this point in time when people need to self-learn a lot more.

[@evansvernon9293]

Hello Lauren how are you doing

[@morganmorrison8775]

Hello how're you doing hope you're safe due to the covid 19 pandemic

[@siobhanquinn4635]

Ninja nerds are the BEST!!!! Thank you so much !!!!

[@keasmea]

Do you explain the difference in immune responses in vaccination vs natural immunity? I’d love to hear the breakdown and pathology rather than the blanket statement that says “vaccines give you extra and more ensured immunity”.

[@itokjongseng9187]

Dx7

[@divinekingston1290]

thats for another video

[@SW-oy5zw]

Yes, especially since one of the head scientists of Pfizer said naturally immunity is far better all the way around.

[@cleartonal]

the shot only recognises one protein (the spike) out of many proteins which comprise the original wuhan covid-19. the external viral protein mutates (is forced to mutate in the environment of mass vaccination) and the immune system then has nothing it recognises. Also, it is BASIC SCIENCE to NOT vaccinate populations during a pandemic.

[@alaak9044]

You are such an amazing teacher , I highly appreciate you 🤍

[@raquelobando7430]

Amazing explanation of these vaccines and how they work. Thank you so much for this video, you're an excellent teacher!

[@genecollinge1265]

Excellent video and very informative ,just two things that puzzled me, Why do the cytotoxic T- cells not destroy the host cell processing the vaccine at that time and not in the future, also the MHC-11 protein only found on B cells, macrophages and dendritic cells are these part of the process within the vaccinated cell?

[@umbra9029]

I guess I'm late to the party, but since you asked: first question - the cytotoxic T cells are activated by the host cells that's producing the vaccine. The reason why they don't kill the host is because they don't code for the entire virus, so they're not recognised as an infected cell. It only contains a very small bit of information that's the spike protein, which will teach the host that spike protein is a threat and he will be able to recognise it in the future. Second question: u mean the MCH-II, they are part of the process of vaccination, but obviously not within the "vaccinated cell", they present the antigens to helper t cells, which will then coordinate the immune response to a more specific one by activating b cells and the cytotoxic t cells. Hope it made sense.

[@aidenkelly9245]

Hooked, interested and understood. Keep this work up, you intrigue me!

[@mrjesushramirez]

Zach THANK YOU For All Your Lectures!! I Continue To Learn and Refresh My Knowledge With All You Do. High Five and Positive Vibes!

[@thegreatesthades9859]

Thank you, ZACH! YOU ARE THE REASON WHY I TOOK MEDICINE. WE LOVE YOU

[@rustyp5810]

Best presentation so far.. very educational...very smart way of showing the whole picture of this pandemic....thank you.

[@roseline_n]

You make studying and understanding way easier

[@sr1834nx1]

This is such an excellent video. I have a bachelor's in molecular biology and I am so glad that there are people like yourself who can break down this topic to make it super understandable.

[@nickfedor210]

When our cells produce the display protein, how do we know that same protein does not interfere with anything else in the cell or other body tissues?

[@monikab1300]

This is the question

[@lizolver1286]

CD8 Protein sounds really dangerous if there’s no diseased cells

[@dallysinghson5569]

We would know by now as the virus infected folk would display the results, doesnt appear like it

[@nitinkarole]

Wow! You make this science look so easy to understand!

[@JordanLukeDawes]

Blown away by this lecture, Incredible.

[@sheilacullen9296]

I wish I could take classes with someone like him talking to the point, explaining and the visuals. Great job and you make it so interesting! Thank you for your time.

[@morganmorrison8775]

Hello sheila how're you doing hope you're safe due to the covid 19 pandemic

[@anthonyreverri5289]

This was awesome, thank you for putting this together!

[@sarahbabiker118]

This is amazing, the way you explained it all is simple and easy to understand, thank you 🙏🏼

[@morganmorrison8775]

Hello how're you doing hope you're safe due to the covid 19 pandemic

[@stylz1]

Man this guy is brilliant. I learned about Covid19 from him back when the pandemic started and this is the only other video I've watch and it's just as informative and well done. Thank you.

[@pragmaticparadox5981]

You learned from this guy? He's been completely wrong about the treatment and the vaccines. All his main conclusions have been debunked and it is all coming out with the Pfizer data they tried to bury for 75 years. This guy is obviously very intelligent but he was also wrong A LOT!

[@stylz1]

@@pragmaticparadox5981 If you're going to try to besmirch someone at least give specific examples. What claim specifically did he make, and how specifically was it proven wrong? Otherwise you're just another wacked out covid denier.

[@allycummins6873]

Thank you so much for this video! You have a way of explaining complicated topics that is like no other. I am sending this to everyone I know in hopes that they watch and educate themselves!

[@sanadezhabad4684]

I've been lookin for sth exactly like this in 3 languages and here it is after 2 month searchin non sense scholars & news. Thank u

[@regantucker9180]

i learned more in this than i did from 10 years of schooling

[@volkhen0]

Got second dose of AstraZeneca two days ago. Zero symptoms this time. First dose I had cold like symptoms for 4 days.

[@thomaschappell9734]

A great explanation: thorough, clear, high speed and interesting. Thanks!

[@dindaire]

I'm so happy you're doing this Zach!!

[@jimmymaynard2456]

DUDE your awesome, I wish I had professors like you during my undergrad...I hope I communicate as well you when I become a teacher.

[@veronicamatharu8097]

I wish we all had a lecturer like you.God job excellent explanation.

[@rohan8483]

You’re so passionate about knowing all this and imparting it to others! Kudos to you!

[@VoiceoftheVeteran]

Outstanding presentation Zach! Your skills make it captivating and I thoroughly enjoyed it! Thank you.

[@stacyannlewis8124]

You are so amazing, i understand everything that you said and got full understanding of it all thank you, you are a great teacher

[@mr.splitbrain2762]

Gotta say that's easy to understand, it may not be at the level of medical school, but for common folks its way more that enough.

[@miracleshappen1711]

Wow, although much of this video went over my head I learned quite a bit. You are very engaging. I could listen to you give lectures all day long.

[@momoslover]

Can someone explain to me why the T cytotoxic cell wouldn’t destroy the host cell processing the vaccine? What’s protecting that vaccine processing host cell?

[@moRaaOTAKU]

My veterinary immunology professor explains like you such a good way to visualize these complex processes she also have nice drawing.

[@alices5531]

Wonderful video! I am blown away by how you explained in such a clear manner. Even a layman like me can understand. You're a great lecturer!!

[@oldmanchipplays.......4413]

This is the first time I think I have missed being in school for some time :-) - Thanks for the nicely paced, and informative walkthrough.

[@chololhey]

You are really the Hokage! thank you for this lecture! Guys we have to protect this guy at all times. 🥰🥰🥰

[@carleencropley1583]

You are an amazing human. I only wish you were around when I was doing my nursing degree 28 years ago.

[@morganmorrison8775]

Hello how're you doing hope you're safe due to the covid 19 pandemic

[@elaineposey]

Teachers like Zach make me excited to learn more. Love the way he presents . Thanks for all the education you do!

[@ravenwave4896]

Im

[@deekircher21]

Zach is a great teacher

[@larryschiff3473]

Nobody could have done a better presentation. That was excellent.

[@emilylerdahl1937]

I love this channel it goes enough in-depth for upper-level Biology courses and yet keeps it simple enough for people without a strong Science background to understand the topics.

[@dorianjasper892]

Thank you for input on the on vaccine processes. I love how you break things down. It's actually making me fall in love with science again, not to mention I actually feel as though I learned something.

[@uDubRiceBoy]

The most detailed explanation I can find! Thank you! One last question, typically, what percentage of the vaccine stay in the injection site and what percentage is carried into the blood stream?

[@rajeshmithun9455]

You are an asset for medical Science. A Jewel in medical lecture. I follow all your video. God bless you, Ninja Nerd

[@MyladyMia]

I love the simple explanation you provided us. Would it be possible to remake this video with the updated information on the vaccine because now we have more information on pfizer, moderna and astra. we also have new choices on vaccine like j&j and sinovac.

[@saramiurazolbrod7861]

Such great material! Thanks!!!!! I'm starting my 2 years of nursing school.

[@williamirwinhunt229]

The man with the Bobble Hat ... Tremendous explanation, systematic and very interesting. TOP hat ... Thanks

[@TT-jc4ur]

When Zach says Beautiful " upon expounding a detailed delineation - he is like the Bob Ross of biochemistry!!!