Waterloo Brain Day Lectures 2019 - Vinod Menon (Stanford University)

[@kennethgarcia25]

While people like Menon wish to add value to their research by mentioning "dysfunction", none of these researchers have questioned the early assumptions of psychiatric theoreticians of the past. The notion that schizophrenia represents a single disorder, or any of the major categories of psychiatric syndromes, with a singular mechanism is not considered possible. So quoting "salience network" because Kappoor and others thought it might have something to do with schizophrenia is much like other notions having to do with aberrant filtering (simply another way of referring to salience networks) or excessive dopamine (due to some very coarse clinical value of reducing DA -D2Blockade). People simply do not recognize that there is something far more central in terms of CNS information processing and that any of the contributing support mechanisms that result in organized CNS adaptive output can be disturbed leading to the various distinct features of psychopathology. I could have told you these things back in 2019 or when I heard of these theories back in 2002, but all these researchers get defensive when an MD clinician tries to speak about network-based models of CNS psychopathology.