Dave Feldman - 'A Very Brief Review of the Lipid Energy Model & TOP SECRET'

Dave Feldman is a senior software engineer, business developer and entrepreneur. He began a Low Carb, High Fat diet in April 2015 and after experiencing a significant rise in his total cholesterol he committed himself to learning everything he could about cholesterol and the lipid system.
As an engineer, Dave spotted a pattern in the lipid system that’s very similar to distributed objects in networks. Through research and N=1 experimentation he has revealed some very powerful data which he continues to share in this presentation and in further detail on his website; www.CholesterolCode.com
This talk was originally presented in August 2021 at 'Low Carb San Diego 2021' and has been graciously supplied by our friends at @LowCarbUSA . For information on upcoming LowCarbUSA events visit www.lowcarbusa.org/low-carb-e...
Please consider supporting Low Carb Down Under via Patreon. A small monthly contribution will assist in the costs of filming and editing these presentations and will allow us to keep producing high quality content free from advertising. For further information visit; / lowcarbdownunder

[@pamlee5716]

These are the experts that I trust and I'm grateful everyday for all of them. I'm healthier because of them.

[@Andrew-ho4vq]

Trust what gets you the results you want, not experts. Trusting "experts" is what caused the global obesity and diabetes epidemic to get so bad in the first place. The corrupt political class can always just arbitrarily decide which experts get the loudest voice as they have in the past, the internet has only just recently begun to mitigate that. Expect politics to interfere in people's dietary choices more and more however as that's the way things are going with governments becoming increasingly totalitarian in the covid era, and for things like veganism to be pushed onto people in the future. Vote like you don't want to have to trust experts or politicians, but like you want to be a free and independent person.

[@dogie1070]

@@Andrew-ho4vq 😎👍

[@denisewittman975]

I love the approach of a non medically trained Dave Feldman. New perspectives emerging

[@MrChezyoung]

As a LMHR, thank you, thank you, thank you. David, you are a star. I’m not worried by it, the body is not stupid and by cutting carbs my BP has dropped to 105/60 and I’ve lost 10kg.

[@ActivateMission2ThisTimeline]

Also the GMO seed oils that are highly processed and go rancid quickly are linked to plaque buildup and heart attacks. Research shows a correlation between seed oil increase in our diets and heart problems.

[@bruce8443]

It's fascinating to see such a professional discussion. I'm glad that the study will be taking so many precautions against unconscious bias and other potential confounding factors.

[@iss8504]

Love that someone is challenging the ldl c hypothesis. This is the only way we make progress.

[@benphartine]

38:00 is about when the Q & A portion gets started. Some very good questions and from well known Doctors.

[@bettykramos1802]

So awesome to see these wonderful giants in the lipid world, speak openly with each other…loved it!

[@carlnelson3893]

Great work, and great minds on display, Thank you for all you all do!!

[@HH-gn9qt]

We are so lucky we have such brilliant and dedicated people looking into LCHF way of life and now the hyper responders. I am both a LCHF and Hyper-responder personally and am extremely interested in the lipid energy model, etc. These men and women bring the science, unlike many/most of the other proponents of a plant-based way of life that to me personally seem like informercials with little science, instead of relying on the preconceived notions of what the "experts" and government have drilling into us for the last 50 years as being "healthy". LCHF for the win, people! PS, there is more and more evidence that given a healthy metabolism (which of course is HUGE), the healthier one is, the higher LDL.

[@U4Eye]

Dr. Atkins has same diet and science professionals attacked him..

[@desertself]

This is fantastic! Well done Dave. The extended conversations at the end are priceless! What a gift. One concern, which one person did raise --- for some of us who have been keto for years, our BHB rarely gets to or exceeds .5 in the morning, and is usuually .3 - we are LMHRs and in my example 20 gm carb per day or less. Only exercise bumps me up, and almost never above .7. Looking forward to seeing the study results! Kudos!

[@thefisherking78]

Love your work Dave! Keep on keeping on!

[@h.o.j2375]

Absolutely fascinating and looking forward to the data from LMHR study.

[@sjaron23]

What an interesting and helpful video. Thank you!

[@pyancey0]

Fun and very educational, thank you!

[@lindabladon9205]

Following closely because I'm a LCHF lean mass hyper responder. But in UK , otherwise should love to have taken part.

[@edwigcarol4888]

The same here. But are you sure not to have a FH heterozygous (less harmful than the FH homozygous of the young girl mentioned) ? I am not confident here because they never mention the ApoB by FH (different types depending on the failing biological mechanism) ... the ApoB by FH and by LMHR. Critical is not have a cumulation of oxydized non-functional ApoB coursing the blood and not being cleared by the liver: their load of cholesterol may even be very low and they are the ones initiating the plaques. Here they do not measure the Apo-B, although this is the relevant factor. (see Peter Attia 'drive' on that topic in a discussion with a cardiologist) In one word i am still worried about my 286 mg LDL-C. Low fat is no alternative, because i tended to insuline-resistance before my LCHF Diet.. And: glucose can damage these numerous Apo-B further.. fructose even more aggressively. Dave Feldmann seems to ignore that. We with too much LDL-C must find a balance between fat and carb and rely on the high quality of them so as to avoid Oxydation and glycolization of the Apo-B lipoproteins

[@craigslitzer4857]

For the skeptics, why would they argue for the study to not take place? Wouldn't they be best served for the trial to take place and have their beliefs reinforced? Pursuit of truth shouldn't be discouraged.

[@buckbuckleyson2259]

His study simply isn't valid in any way. His in particular. Not speaking against low carb at all. Feldman has simply left the building on credibility.

[@kaydenl6836]

@@buckbuckleyson2259 for what reason?

[@craigslitzer4857]

@@buckbuckleyson2259 Maybe I misunderstood but I got the impression they hired the testing clinic to make sure the experiment produced meaningful results, one way or another.

[@bishamuesmus301]

@@buckbuckleyson2259 explain why you believe that?

[@Chris-zd8cs]

This is what is known as a slap and run. No credibility himself, he hurls and insult and leaves before he can be challenged. Also known as a coward.

[@CashMoneyMoore]

The ground floor of an important day in science

[@MarkRose1337]

That was enjoyable to watch. A great conversation.

[@keywestfan2503]

This is such a fascinating and complex topic. We clearly have been asking the wrong question with regard to whether LDL-C is a risk factor. I think this study is asking the correct question. Does the MECHANISM of LDL-C elevation matter? I think yes. I think that an overweight, hypertensive, no exercise, eating a SAD person with elevated LDL-C is different than a keto/carnivore athlete with elevated LDL-C. Pathology vs physiology. Also fascinating to me is that as humans, in general, we have no clue as to what the proper diet is for us. No other animal has this problem. Every other animal knows exactly what to eat in terms of its proper diet. Also fascinating is that we as humans, also seem to be the only animals that suffer heart attacks. No other animal seems to have any appreciable rates of ischemic heart disease/infarcts. Lions, tigers, dogs, wolves, etc who eat ONLY a fat laden meat diet don’t have MI’s. So clearly there is some X factor for us humans that would be responsible from a likelihood and plausibility standpoint. Just my thoughts

[@phatpoint]

Fantastic work…. But it’s more about real foods matrix complexity than macronutrients and avoidance UPF formulations to mitigate IRS and the nexus of commodity food diseases. The mitochondrial metabolic theory will complement these ideas quite well…. Quite complex to put in perspective, many mechanisms play a role in IRS…. immune activation and the need of mitophagy is key to mitigate IMM/CL remodeling, oxidative stress and proton motive forces affecting ATP productivity. Cheers 🥂

[@az10sbum1]

It seems to me that the initial data alone will be very interesting. Can it be released in an anonymous manner? If these patients in the top 1 or 2 percent ldl average in the bottom third of age adjusted plaque, that would be very interesting. I'm really interested in the predictive ability of the trig/HDL ratio vs other markers

[@bidnow2946]

1:03:24 "The CAC score is useless for following somebody from one year to the next." This knowledge bomb needs much, much more discussion.

[@robh8057]

I'm hoping that Dave can find enough participants for his experiment/study.

[@claybutler]

That will not be a problem. I'm involved in both of his Facebook groups and there's thousands of us.

[@ActivateMission2ThisTimeline]

The seed oil vs saturated fat use is also a variable that needs to be addressed.

[@Gengh13]

Awesome, this is how the medical field evolves.

[@vas4739]

This was EXCELLENT!!! Was that Nina T in the audience asking a question?

[@rainermaelger4726]

Danke

[@inharmsway1965]

I’m 58 years old, my LDL is 211, HDL 77, Trigs 50 and VLDL 6. I eat less than 20 grams of carbs per day and still have 15 pounds to lose. Am I a LMHR?

[@obfuscatid]

I wonder if LDL is the culprit for high correlation with atherosclerosis or subcomponents gLDL / VLDL / sdLDL.

[@1aliveandwell]

Does anyone have a good CAC score but a test of high non Calcified plaque ?? Does the CT angiogram show all plaque or just fatty?

[@edwigcarol4888]

My angiolog in Germany answered that question: yes plaques with and without calcium deposit are checked. (I had none of them in the carotides)

[@cutabove9046]

CT angiogram shows all plaque which includes soft and calcified. And no, you can't have a zero score on a CAC and have calcified plaque.

[@maarten7]

OK - this really clarifies what you are doing. I found you to be very unclear before. I have heterozygous FH and don't qualify. I find the "traditional" ketogenic diet terrifying, but I do keep my carb intake low - moderate (under 100gm.) but also my saturated fat intake is very low. (The only fat I consume in any significant amount is fresh-pressed EVOO.) I don't consume refined carbs (including sugar) and also take a statin. Thus far, I think I have gotten my condition under control but I still worry.

[@johnutube5651]

Initially when you start diet, your Triglicerides and LDL will raise as your adipose tissues release these substances into blood, did I listen that right ? . Later when you stablize your weight these will be normalized, correct ?. When I started diet in 2018 end I also had steep increase in lipid numbers. Sooner on making some dietary changes without compromising on low carb, i.e. increasing fibers and unsaturated fats and cutting saturated fats to a certain extent, I could revert back to optimum Triglycerides and LDL. Now after, listening to this, I feel I could increase saturated fats a bit more into my diet. Initially I started this diet for managing pre-diabetes and not for weight loss nor for aesthetic reasons.

[@edwigcarol4888]

Nothing that he presents is really exact. We should better check elsewhere. He has neither an PhD nor a MD. I started LCHF for the same reason as you did. I learned that fat cells will only release fatty acids if the intake in exogene fats do not cover the needs. Only Fasting triggers the adipocytes to release FA in the bloodstream efficiently. Or intermittent Fasting over 16 hours. On a Keto diet one can put on weight. I did slightly... till i took less fats in my meals and more importantly till i sticked to that daily 16 to 18 fasting window.. I do not take PUFA in liqid form because they are too susceptible of oxydation und that is what is actually harmful. PUFA only in their natural setting: nuts and fishs (no fishoil, to 90 % oxidated already when on sale. ) Saturated Fats are safe: no oxydation. (Coconut's oil, butter, ghee) I came to the conclusion that the most important thing is to remain aware of the handling of fats' products and their cooking.. oxidation and 'cracking' that is what counts. Therefore cut off on packaged food and restaurants. With your metabolism you react differently than my body does. I believe we are too complex, nobody can really control how the bio-variables evolve in response to the life style (including sleep and circadian rhythm). So i got a slap in the face with an LDL-C through the roof. Nothing false to fix. No solution at sight... So Each one experiments for him/herself. But ,am i false?, I related the TG to a high fructose diet or to alcohol intake Otherwise we get VLDL first ?

[@faiosung]

Jo C, i am at early stage reducing sats and increasing fibres, if numbers improve, i will continue at the same levels. i am hoping i adapt to enjoying better choices as i have to avoiding bad carbs

[@susantroupe9341]

@@edwigcarol4888 I see it as an advantage that Dave is NOT an MD. Most of them seem stuck to the “ heart/ fat hypothesis” that they look no further. Kudos to Dave for starting the ball rolling on this topic. It appears that he will be in collaboration with giants in the field of lipidology and cardiology in his quest …... I can’t wait to see the results!

[@Mr_Fission]

The USDA hears Dark Souls boss music when Dave Feldman steps into the room.

[@pureabsolute4618]

Hmm... My only beef is that LDL and VLDL are an interesting combination that might have a more complicated story-line than "LDL BAD". Even the LDL-BAD argument seems to be kinda dumb - the example with the FH girl is a good example - an analogy would be someone who makes the argument that the reason someone dies with they are exposed to too much water means that water is definitely bad. It gets worse though - VLDL is considered universally bad, but LDL not so much. One of the bad results people get from statins is that statins tend to reduce LDL, and not so much VLDL, leading to greater ratios of VLDL in the blood. Unfortunately, these nuances were not to be found in the "brief" talk given here. Having said that, assuming that there are no other interventions in these people's diets and medicine, one might expect LDL to go up as a whole, and a study that shows that that in its own right isn't bad would be a good thing. Perhaps it will shut the LDL BAD crowd down long enough to get better studies done with better nuance. I look forward to the results.

[@ActivateMission2ThisTimeline]

That little girl also ate lots of carbs like all kids and her cholesterol oxidized causing build ups in her arteries and veins. They should have put her on a low carb diet which would have protected her heart IMO.

[@nitfitnit]

Age is a major factor in the CVR calculator. I doubt anyone over 55 will qualify.

[@claybutler]

I don't believe there's an age cutoff because I'm 55 but the reason I wasn't included is I did take statins for 2 years earlier. So they are trying to eliminate any confounders as possible. I was really bummed not to be included. I wish I never taken the statins.

[@MrChezyoung]

56 and I would qualify but I suspect it’ll be a small percentage of the 3% of lmhr’s!

[@shelchicago8997]

The clinicians who align with the low-carb diet (such as those in this audience) look healthier, leaner, younger than those who dismiss it.

[@anomamos9095]

One of the greatest dangers of medical science is medical religion. Medical religion is where actual science starts to take a backseat and personality and dogma drive. I seriously question the pronouncement that high cholesterol was the cause of the little girls heart disease. The heart disease was likely caused by whatever was causing the high cholesterol. In many cases people have died because symptoms have been mistaken for the disease and diseases have been mistaken for the symptoms. For example Depression may not be a mental disorder requiring antidepressants but a symptom of diabetes or cancer. And that is just the tiniest tip of the iceberg of misdiagnosis that occurs due to medical religion.

[@LTPottenger]

scientism. it's corrupt promotion of agendas not science

[@keywestfan2503]

One thing I was thinking with the little girl. She has elevated LDL-C but is she still eating what 6 year old typically eats? Cereal, juice, snacks, etc? How much of a confounding variable is inflammation etc?

[@director2345]

I agree that the little girl may have had an underlying serious artery endothelium issue with such damage that it required very high levels of LDL to try to repair it...just sayin..

[@JasonCunliffe]

1:07:00

[@matejsmrekar1218]

I hate the term bio hacking.

[@kayallen7603]

Cholesterol is NOT a problem. Period. Stop worrying about it. See the Health Collaborator for more information.

[@iss8504]

It's a problem because it's been tagged as a problem. If we don't find something definitive to prove it's not a problem, the standard of care won't change. If your ldl c is crazy high and your CAC is 1000, like mine, this isn't academic anymore. I need to know if this diet is going to help me or not. There are lots of us. We fall outside of the guidelines. We feel great on keto and we have no comfort of a zero CAC score.

[@pointshealthcoaching8474]

No, they lack enzymes needed to utilize cholesterol, so it accumulates in blood. It's the lack of ability to have essential nutrient, cholesterol, perform It's many functions. This is blaming firemen for the fire. The cuz of FH is not high LDL. RE: Bart Kay podcast.

[@highrzr]

Sorry, total LDL, just like with total cholesterol, even if it is high is not the problem nor an indicator of anything It's the oxidized LDL that is. What's more important than total LDL is what pattern or size the LDL is. If most of the LDL is the large fluffy buoyant cadriovascularly neutral variety or pattern A, you're probably going to be fine. If the LDL is more of the small dense LDL pattern B and especially the oxidized LDL, then you're probably not going to be so fine.

[@brianzell99]

This guy isn't a doctor so I will take a listen.

[@freddyt55555]

10:34 An interview with our Principal Investigator 11:11 Principle Investigator and their team? 11:25 Principle Investigator -- Dr. Matthew Budoff Need to spell check those slides. I chuckled at the first misspelling and cringed at the second one.

[@tserevenad]

Well there are grammar nazis and there are scientists…guess you got to pick your battles accordingly…

[@LoveOfATree]

I might have missed this, but are you controlling for people having been vaccinated? The heart side effects might be rare, but are present and can be severe. It might completely mess up this rather wonderful study...

[@kaydenl6836]

There are no increases of heart issues in vaccinated vs unvaccinated people that is anywhere significant to pose a threat. Controlling for covid/previous covid infection would be a far better variable

[@claybutler]

There is no evidence that getting the vaccine is damaging the heart but let's just say it is. It's wouldn't be damaging it by causing cardiovascular disease which is measurable. It would be some kind of damage to the muscle. So it still wouldn't matter for this purpose.

[@catchristo9406]

​@@kaydenl6836We are seeing a sharp uptick of younger vaccinated adult patients who have fast growing cancers, blood clots, and rare autoimmune disorders, so I would not be so sure.

[@ladycactus110]

Please... it’s Principal Investigator, not Principle Investigator.

[@tserevenad]

Geesh…..REEEE

[@AZ89231]

🤦🏼‍♂️ talking about HRT, that was cringeworthy - WHI excluded women who had symptomatic benefit from HRT in the run in stage - no increased risk of breast cancer, better prognosis of breast cancer if they were diagnosed while on HRT, significant improvements in a myriad of other clinical parameters. Read the actual clinic trial data instead of the headlines before you make yourself sound so ignorant - or pick up some of Avril Bluming’s work at least. Excited he’s the principal investigator though - stick with cardiology and radiographic imaging! Dave Feldman for a Nobel prize!!!

[@U4Eye]

I Never trust Subjective Science

[@BR-hi6yt]

Dave Feldman is very beneficial for the proper human health community - but I can never understand what he's saying for some reason.

[@spaceghost8995]

These talks require about three listens to really get it. You don't have to understand 100% of it. I struggle too.

[@linneasimchah1621]

My first intro to Feldman was interview with Saladino. I'm educated in the health sciences and have no problem immediately getting Saladino's syntax, but when Feldman talks, it's like what is he even saying? Saladino would always sum up Feldman's comments each time because I'm sure Saladino knew Feldman has odd word usage. Feldman is smart though, and glad someone like him is interested in looking in depth at something as meaningful as lipid interpretation. Definitely can't rely on allopathic medicine for accurate explanation of lipids.

[@tserevenad]

Just keep in mind these people are geniuses and scientists. We just need to grasp the basics for now.

[@contrarian717]

I read the comments only. Helpful

[@danielrodgers3002]

Ugh.

[@gregnixon1296]

Could you at Low Carb Down Under post shorter videos from time to time? It would make watching a complete subject a bit easier.

[@__-bc4bs]

Fly? Are you only having people that have been vaccinepoisoned or are you considering actual normal and healthy unpoisoned people in the study too? #AdamNallyMD

[@peterschmid9878]

It's interesting that anyone who questions this study has his or her comments deleted. Something is not right here.

[@pomegranate6221]

Whole crap ....listening to this was like watching grass grow!!! And they have no answers???? What a friggin racket!! In over 2 years they couldn't study, track the calcium buildup in the veins on their 7,000 people on Facebook give me a freaking break!

[@rosevanderreijden3216]

It seems to me that this study is more about the safety of keto than anything. What do you consider "lean mass" anyway? Most of the people I know on keto are not very "lean". I would be more curious to know if keto shortens one's life - which I presume it probably does (at least when compared to a WFPB diet.) Also, I don't think you can uncouple the keto diet from the horrors of factory farming. Sorry to bring up the unpleasant subject, but we ARE going through a climate crisis -- not to mention the untold suffering of animals. Peace.

[@billyt9921]

I've lived both vegan and keto lifestyles. I am much much healthier, lower bmi, lower BP, lower resting heart rate, more and constant energy, no longer have GERD, very rarely feel hungry and higher percentage LBM - on keto. I was just about ok on vegan, but felt like I was slowly declining the whole time.

[@catchristo9406]

I was a miserable vegan before going Ketovore. Feel great now.

[@DennisBolanos]

It’s always the same handful of “experts” showing up on this channel.

[@benphartine]

No it’s always the same trolls like you showing up on this channel. Did you see where it says this is a … review…? Why do you follow someone if you heard it all already. What do you expect, maybe a new set of experts every time? Do you go to a different doctor every time? Maybe the new doctors can gives you a better prostrate exam than the last; don’t laugh until you tried it! He said that he worked with these experts. Do you expect to go to work and see different coworkers every time? Think of how shortsighted your statement was and schedule yourself for another prostrate exam by someone else. 🙈

[@Dan-gs3kg]

Anything wrong from principle? Or just an appeal to authority?

[@adorinadorin]

So invite others!

[@LittleRadicalThinker]

It’s always the poisonous Neal Bernard in the physician committee channel, the one and only one doing all the poisonous talking to his audiences.

[@DennisBolanos]

@@benphartine I see I hit a nerve with you (as demonstrated by your little tantrum). But that's OK. It probably wasn't the first time. I was making the case that LCDU would benefit from expanding their network of experts. Have you wondered why they keep featuring the same speakers, over and over? Maybe it's because only fringe experts will agree to appear on this channel.

[@nballa]

Don't believe the fasting/keto hype. Its like saying holding your breath is good for you. Do not interfere with body's natural feedback mechanism.

[@LTPottenger]

It's called normal human environment. It's only recently people stuffed refined carbs in their mouth 24 hours a day, until now everyone fasted in every culture and extra in the winter in bad years.

[@craigslitzer4857]

There are natural feedback mechanisms in place during ketogenic states, during fasted states, and during standard fed states. Which mechanisms are encountering interference?

[@JohnSmith-oo7ig]

What's it like being so stupid?

[@stevephla]

What if my feedback mechanism triggers my constant craving for cake and ice cream? Is that natural? Or is it an acquired, unhealthy addiction from insulin excursions? The optimum human diet, if there is such a thing, probably looks a lot more like keto/fating than it does the garbage many people (not all) eat. Epidemic obesity is appearing in more and more countries.

[@tmoney2261]

What's your reasoning?