DNA Replication- Eukaryotes

DNA Replication within eukaryotic cells is a tightly controlled process that uses several enzymes to create an identical chromosome in preparation for cell division. In this tutorial we will summarise the whole process, focussing on individual components in later lessons.

[@bertrand00956]

Your video is great, the overall process is well explained. However, I have to say I'm a bit disappointed by the lack of comparison with Eukaryota DNA replication. You explained the general replication of DNA, not of Eucaryotes. First of all, you didn't explain that DNA replication is a process that occurs in 3 stages : initiation, elongation and terminaison. You explained the elongation (and not for Eucaryote, SSB are for Procaryotes). You don't talk about origins of replication, topoisomerase, the Eukaryotic replisome (DNA pol alpha, delta and epsilon), the disassembly and reassembly of nucleosomes, the ORC and pre-RC and the terminaison. And of course, you forgot to mention Telomeres. So the title should be "replication of DNA in general".

[@Medictutorials]

+bertrand bouillon Hi there Bertrand. I try to keep all my video below 15mins if possible to get a really strong focus on important points. As this lesson is aimed at first year students, it is all the information they would expected to reproduce on an examination. You can bet I'll be making videos in the future on the roles of Telomeres and all the rest, but to avoid confusion, I only include the info that is expected of different college year levels. Thanks so much for the feedback, I hope my videos continue to be helpful to you in your studies! :)

[@olansean9868]

I observed that too

[@monatse3716]

Can U please add tutorials of the nervous system and nervous tissue.

[@wrickchakraborty5556]

Its not eukaryotic process its the basic prokaryotic process..... though explanation is good the title is misleading

[@ClasssicAri]

You fucked up explaining the 5' to 3' during the primase.

[@dominicquiros7014]

Good video but Primase is not used in Eukaryotic replication. DNA polymerase alpha is the "eukaryotic primase" and RNAseH is the "eukaryotic DNA polymerase 1"

[@aizvass424]

It is 2 am, and im reviewing this for my exam at 10 am. Thank you so much for the material

[@jessicadaniellegeiger4036]

This video is a weird mixture of Eukaryotes with Prokaryotes

[@zvuvomo]

Great video, but I'd like to know if you have a more advanced one explaining the different types of DNA pols and being a little bit more profound overall. Cheers.

[@aortaunicorn7179]

+zvuvomo ya me too id like that

[@Medictutorials]

+zvuvomo Hey there, this video is aimed at first year students so I haven't gone super in depth, but I will definitely be making a more detailed version eventually covering the different polymerases :)

[@Squigg_lerain]

you have incredibly similar handwriting to me, it is beyond easy to read

[@isaacteo8414]

studying for my SAT bio. Thanks so much for this video! Really helpful and simple to understand!

[@aqsanadir153]

Is me initiation of replication Jo complex h uska to Bataya hi nhi time wate

[@aqsanadir153]

Bakwas

[@zikremasoomeena.s8434]

Your is outstanding... The process of DNA Replication become well understood by help of this video.. But i have to say im bit disappointed that there is no explaination why okazaki fragments are formed in lagging strand.. - via YTPak(.com)

[@safabraik9719]

primase enzyme isnt for prokaryotic and for prime synthesis in eukaryotic is dna polymearse alpha

[@shreyasgham3632]

It was really great.....you made DNA replication fun for me...Can you make a video on types of RNA and their function?please. It would help me a lot. If you can't then just suggest me some good video on youtube from any other channel that does. Thanks Again...

[@schoolcalilove3225]

Thank you so much! Your lessons are detailed and not overbearing. I appreciate all the time that was put into each video. Your lectures are helping me with Hesi A2 and other college courses.

[@mmaking8664]

What about the roles of DNA topoisomerases? Can you please explain that? Its quite confusing.

[@melissarainchild]

Thank you! I'm studying so...any extra info helps! And...gues what, I understand this now :)

[@Mstaples08]

Oy. Misspelling "complementary." ...... ;-)

[@allaboutmyillustration]

Thanks very helpful for me

[@AdamGibiGulyabani]

you rock

[@sereshkreha4854]

Wow ! DNA replication was helpful

[@matildah5736]

Again thank you this has helped so much :)

[@Medictutorials]

Matilda H You're very welcome :), and remember, science is coooooool!

[@hungchau9628]

Please don't stop making videos. I guarantee you that these videos are much much better than Khan Academy or any other video's I've seen.

[@Medictutorials]

Thanks for the kind encouragement Hung! I am planning on starting videos again soon that are a bit more professional looking and more interactive for you guys studying!

[@fizzy7487]

This is awesome! You made the process sound so clear and simple. It's very helpful, thank you!

[@barbaramunozaguado7078]

I'm a first year student and seriously, we've talked about different types of DNA polymerases, the helicase named mcm-2-7 and i was expecting some of that content. I already studied this process at this level of detail when i was still at school... Seriously?

[@Markolio95]

Thank you for this explanation!

[@vatsaldholariya5326]

Thank you for explanation.

[@lin.lilium]

hey first thank you fro this awesome video

[@anacolombia33]

Very helpful! Thanks!!

[@loloj1553]

Great video..thank u

[@rc-uz3mv]

really helpful!!!! thanks!!!!!!!

[@bamlakkassahun3513]

Gussee what it i so disgusting

[@samrajanburasu8183]

Helped a lot thanks 🙏

[@rlogeshwaran6165]

Really NICE

[@hassanbhatti1568]

Loved it... ❤

[@H2Otoo1]

what about the end problem? Telomerase?

[@Medictutorials]

H2Otoo1 Hi there, Telomeres and Telomerase is a slightly advanced topic when it comes to DNA replication, I will make a video discussing this topic but for first year courses this is usually not covered. Check back soon and I should have something up :)

[@smithgabrielle101]

this video was so helpful thank you !

[@Medictutorials]

Gabrielle Smith You're very welcome Gabrielle, good luck with your studies!

[@gabbypugh7773]

Your videos are awesome, keep it up dude :D

[@Medictutorials]

Gabby Pugh Thanks Gabby, I'll keep making them as soon as I can :)

[@owaisulhaqdanish3340]

Thanks for such a beautiful explanation. 😊