DNA Replication - Origin of Replication (OriC, ORBs, ARS etc.)

[@ViniciusSantos-mv6zt]

I've been searching for videos that explain replication's origin simply but in detail, just like you did. Thank you very much!

[@rtcoffee1235]

I love your videos man. Just enough depth for a graduate-level drilldown. Thanks a lot!

[@alexanderlarge9888]

Clear and Precise - Great video, thank you.

[@lavanyasahu3960]

Fabulously explained ❤............ Thanks a lot for the video.

[@merttantari7912]

Great explanation , helped a lot ... you're the best !

[@gurdeepkaur2814]

That was very nicely detailed video thank you :)

[@villagecouncilforskilldeve8539]

11bp and B1 B2 and B3 are only restricted to budding yeast and some other related members but the ORIs in Schizosaccharomyces pombe are completely different. They are more similar to higher eukaryotes!

[@villagecouncilforskilldeve8539]

You detailed explanations for other aspects of replication origins are well appreciated.

[@areejnawaz7971]

plz share references of the information you shared in the videos

[@WHY-mi8ng]

I love it 🤩 Can you also make same playlist on Cell signaling and its pathways 💕

[@godbloodyyt1344]

Thank you ❤😊

[@JasminaBegam]

How many 9mer repeats are there? Is it four ? In some book it is written as five 9mer repeats

[@theCrux]

There are 10-15 9nt repeats in general. R1 R2 R3 and R4 are considered moderate to high affinity. Others internal ~9nt sites are not as high in affinity but cooperatively act with R1-R4. All these repeats are usually 5-11 nts; only R1 R2 and R4 are close to 9nt. I would like you to revisit my comments at 8:30 mark in the video. Also note that this oriC organization is a consensus. Depending on the bacteria, it may be that you have all R1-R5 available, some only have R1-R4, and others have some combination of internal sites added or removed. This picture is a consensus of expectation, not a fixed/rigid picture of every single oriC in bacteria.

[@JasminaBegam]

@@theCrux thank you for the information. Your videos are much helpful. Keep making more such videos🙏🏻🙏🏻

[@devilsempire3963]

Is there no R5 region been present ??

[@theCrux]

Please pay attention at 8:55 for my comments on Region 5

[@devilsempire3963]

@@theCrux oh ohk ohk thanks