Do Alzheimer's Medications Work?

There are several medications out there that are designed to slow the progression of Alzheimer's Disease. Learn a bit about how they work, what families think about their effectiveness and my opinion on them, too.
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A bit more detailed information about Donepezil and Memantine:
Donepezil or Aricept is what’s known as a cholinesterase inhibitor. When a person is suffering from Alzheimer’s disease, they begin to have less and less of a neurotransmitter called acetylcholine who’s job is to carry signals from nerve cells to muscle cells. Acetylcholine plays a vital role in muscle contractions, memory, motivation, sleep and learning. The brain also has an enzyme called acetylcholinesterase. This is the enzyme that helps to break down acetylcholine so that it can be recycled and rebuilt into new neurotransmitters for the next message.
So, the rationale behind Donepezil is relatively simple: if you block the enzyme acetylcholinesterase from breaking down the acetylcholine, then more of it will remain and the brain can continue carrying signals between nerve cells and muscle cells.
Memantine is what’s known as an NMDA antagonist. So, instead of the neurotransmitter acetylcholine, Memantine works by slowing the transmission of a different neurotransmitter called glutamate. Glutamate is the major excitatory neurotransmitter in the central nervous system. It plays an important role in learning and memory. But, it is thought that too much stimulation by glutamate may over-excite nerve cells and cause them to die. So, by blocking the effects of glutamate, Memantine may protect nerve cells from getting overstimulated.
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(answer at bottom)
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🙋 Answer to Cryptogram: It may be worth it to try and see if these medications can help them "be"
00:00 Intro
02:07 Donepezil (Aricept)
03:22 Memantine (Namenda)
04:44 Dementia Medication Effectiveness

[@yehman71]

My dad was put on donepezil about a year ago. The side effects, primarily diarrhea, were bad enough to stop the treatment. Last week we decided to try memantine. Fingers crossed!

[@cmo8015]

My mother is on both of these. She has done really well. She’s probably Stage 6 Alzheimer’s and the change in her was noticeable. She’s 88.

[@CrackingtheCodeforCaregivers]

Thank you for sharing :) I'm glad they are helping.

[@daizeofgrace]

We are awaiting an new MRI & PET scan this month to understand better what’s happening to my husband. He has bipolar disorder so his neurologist only felt he could take the Namenda. He’s been on it about a year. He definitely got better after the dr upped the dose but has experienced a recent increased cognitive decline. Once we get the test results we can discuss the medical options to see if he remains on it or not. Thank you for the educational video. I’m trying to learn everything I can to help my husband have the best life he can.

[@patriciawilson1191]

Wonderful & helpful information-wish the pharmaceutical industry would provide this information! Thank you!

[@CrackingtheCodeforCaregivers]

Me too. Thank you!

[@oneseeker2]

No TFTD.

[@82spiders]

Fix your sound.