Dr. Mario | Versions Comparison | Game Boy, GBA, NES, Arcade, SNES, Wii, 3DS and more

✅ Decide which is the DEFINITIVE VERSION of Dr. Mario / ドクターマリオ Dokutā Mario (Nintendo, 1990).
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This comparison features gameplay of the first level of the following versions:
0:00 Game Boy / GB (1990)
1:01 NES / Famicom (1990)
2:02 Arcade (PlayChoice-10) (1990)
2:50 Arcade (vs. System) (1990)
3:51 Super Nintendo / SNES / Super Famicom (Tetris & Dr. Mario, 1994)
4:44 Super Nintendo - Satellaview (BS Dr. Mario, 1997)
5:51 Super Nintendo / Super Famicom (Japan Release, 1998)
6:36 Game Boy Advance / GBA (NES Classic Series, 2004)
7:37 Game Boy Advance / GBA (Dr. Mario & Puzzle League, 2005)
8:26 BONUS: Nintendo 64 (Dr. Mario 64, 2001)
9:47 BONUS: GameCube / GC (Nintendo Puzzle Collection, 2003)
10:48 BONUS: Nintendo DSi (Dr. Mario Express, 2008)
11:43 BONUS: Wii (Dr. Mario & Germ Buster, 2008)
12:51 BONUS: Wii (Dr. Mario Online, 2008)
14:13 BONUS: Wii U (Dr. Luigi Classic Mode, 2013)
15:34 BONUS: Wii U (Dr. Luigi Operation L Mode, 2013)
16:20 BONUS: Nintendo 3DS (Dr. Mario: Miracle Cure Classic Mode, 2015)
17:48 BONUS: Nintendo 3DS (Dr. Mario: Miracle Cure Mode, 2015)
21:28 BONUS: Nintendo 3DS (Dr. Mario: Miracle Cure Dr. Luigi Mode, 2015)
22:11 BONUS: iOS/Android (Dr. Mario World, 2019)
👉 Check out more EVOLUTIONS of MARIO GAMES HERE! • Super Mario Bros. 🍄 Ve...
We've included a lot of bonus versions because although games from Nintendo 64 to above are considered out of the main Dr. Mario games, all of them share the same core gameplay and features Classic Modes that emulate the classic. There's an exception though, Dr. Mario World for iOS and Android, a game that has notable differences with the original.
Which is your favorite port or conversion? If you liked this video give us a like, share, comment, subscribe to our channel and don't forget to click the bell icon to receive new updates.

[@retrosutra]

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[@LuisHernandez-uk9ub]

All

[@user-je3fd8ks7x]

吃

[@zahraz8277]

Retrosutra why you have 2 replies

[@Jbgfesckkjvjekkwmbzbsbbux]

Nintendo 3DS sanki Wii U Gibi

[@Jbgfesckkjvjekkwmbzbsbbux]

Ve Nintendo Wii Gibi

[@vertz1515]

Man, the newer games aren’t that widespread. After Dr. Mario 64, I don’t think they really went with physical releases anymore. That’s probably why I sometimes forget that Dr. Luigi exists

[@Cyberbrickmaster1986]

After Dr. Mario 64, the only physical versions after that were on Game Boy Advance. Everything else was digital only.

[@Kyle07]

Digital games on the game cube?

[@user-el6kl4go1s]

​@@Cyberbrickmaster1986😂

[@Cyberbrickmaster1986]

@@Kyle07 I keep forgetting about the one on Gamecube.

[@TheDerpyDolphin]

Dr Mario is my favorite puzzle game. I recently completed lvl 20 High on my NES

[@baldingfox77558]

Gj

[@emeralddagoat]

NOICE

[@QueenJeeode]

Mine too

[@Escanimations]

Wow! Me too!

[@bland9876]

Try Tetris 2 it is like a single player version of the flashing vs mode plus the pieces are different shapes. (Also it's match 3 instead of 4)

[@Mariohenri90]

Great video. It's nice to see Dr. Mario fans. I wish they would make a new Dr. Mario game similar to the 64 one and have online mode like Dr. Mario Online RX

[@coutamaxplayer538]

yeah, maybe with some feature of miracle cure and world

[@MikeChimeri]

My favorite version is the first one I played: NES. I've played most of the rest except for arcade and Wii (and GameCube, since I'm in North America). In Hepburn romanization, the Dr. Mario World voice actress was asking "ledi?"

[@Cyberbrickmaster1986]

The Gameboy version was also pretty good, assuming you could play it in a way where you can easily make out the different shades of monochrome.

[@gametogenesisjustukshoes1698]

0:00 - 1:01 Dr. Mario (1990 - Game Boy & NES) 2:51- 4:44 Dr. Mario (1994 & 1997 - SNES & Satellaview) 6:36 Dr. Mario (2004 - Game Boy Advance) 7:37 Dr. Mario & Puzzle League (2005 - Game Boy Advance) Bonus: 8:26 Dr. Mario 64 (2001 - N64) 9:47 Dr. Mario (2003 - GameCube) 10:48 Dr. Mario Express (2008 - DSi) 11:43 Dr. Mario & Germ Buster (2008 - Wii) 12:51 Dr. Mario Online RX (2008 - Wii) 14:13 Dr. Luigi (2013 - Wii U) 16:20 Dr. Mario & Miracle Cure (2015 - 3DS) 22:11 Dr. Mario World (2019 - iOS & Android)

[@BlueStinger475]

I remember many years ago buying Dr.Mario Express for my DSI, i only bought it because i saw it on that DSI+internet video, I was so young

[@user-je3fd8ks7x]

tyryyujk2

[@flore1709]

I USED TO WATCH THAT VIDEO OVER AND OVER I USED TO LOVE IT, DON'T EVEN KNOW WHY

[@samuelthehobo4441]

The SNES version has some wierd samples for the music, although the bass is really good.

[@nicholasgawler-collins5754]

I've found that the song sounds better when played at a lower pitch. I think it's because some of the instruments sound a little off-key. You know that "squeaky" part after the first chorus? I think that's an imitation of what the viruses might sound like.

[@samuelthehobo4441]

@@nicholasgawler-collins5754 it does sound off-key a bit, if that’s what the viruses are supposed to sound like then that’s just plain odd.

[@MarioWithTheCrowbar]

I think dog sings fever music in this version.

[@13gamerbullet]

@@samuelthehobo4441 I mean, the yellow one is literally named Weird. You can hear another sound bit of those viruses at 9:35, they're truly making that noise. 5:25 if you want a quick reference to the snes one. I think they're "singing" Fever to be honest. Might even directly be the red virus, Fever.

[@samuelthehobo4441]

@@13gamerbullet oh that’s interesting, to be honest I’ll probably stay with the NES version since it’s the better game all around.

[@GroundMemory]

I love videos like this. And I like your onscreen text box graphic, a simple and effective retro aesthetic. Good stuff!

[@Cyberbrickmaster1986]

If they make a Dr. Mario on Switch (and I hope they do), they should bring back the songs: Cough and Sneeze as well as the option for playing the songs randomly, which was sadly missing in Miracle Cure. They could even add two more songs for Dr. Luigi, and maybe call them something like: Stuffy and Wheezy.

[@whyrwehere]

They should have a Dr.Luigi mode

[@tolstartheking]

@@whyrwehere And story mode with all of the playable characters in the series. A Doctor Mario Ultimate of you will.

[@lazyboi4187]

Anyone else gunna talk about how Luigi just straight up uses the usual viruses to represent the weird ones in that game on the side..

[@bhavigpointi4035]

Love your videos, keep up the good work! Also want Bart vs space mutants soon

[@runayemi3256]

La de NES siempre tendrá un lugar en mi corazón ❤ cuándo era pequeña me encantaba ver a mi mami jugar éste juego, y la valentía que tenía ya que ponía el nivel 20 y la mayor velocidad.

[@grupointellectus9816]

La versión del sistema de entretenimiento de Super Nintendo es mejor.

[@iczev]

Dr Luigi gives double prescription. What a savage!

[@fernandosandoval593]

A mi la version de Dr.Mario que mas me gusta es la de NES,es insuperable segun mi opinion.

[@Kagemorou]

What about Dr. Wario? It's the full Dr. Mario, but with Wario-themed sprites unlockable on the very first Warioware Inc. on GBA.

[@eutrader74]

Eh I don't like WarioWare microgames creep me out

[@Kagemorou]

@@eutrader74 I can respect that, even though I thoroughly love that game.

[@bland9876]

It's not just a simple reskinning of Dr Mario because for example if you break a piece off you can push the down button to make it move faster. In the 3DS version the pieces move faster but you don't push any buttons.

[@carlosemilio5180]

I can't believe they didn't add a hard drop until 18 years later

[@dianaloayzat4975]

And you can thank Dr. Mario Express for it!

[@PokeTube]

Hard drops annoying sometimes but only because sometimes you accidentally hard drop on the wrong virus

[@angelica5099]

Sk

[@beatleelaloisolaloiso6670]

Si NO ES UN ABRAZO GRANDE QUE ME HA RECIBIDO POR LA TARDE DE LAS FOTOS DEL DOMINGO DE LAS FOTOS LA LA A LA LA TARDE LA LA A LA A A EL DOMINGO Au

[@vittosphonecollection4134]

??? There are hard drops on the Wii... Just press up...

[@MKF30]

Great video! I love Dr. Mario, own most of the version here except a few I dont have the systems never heard of or the Wii U version but played it at my friend's place. I do have the NES, SNES, N64, 3DS, Wii. The iOS version sucks lol. I love these games I've been on the leaderboards as 1 tied with others on the Wii version and was 28 on 3DS and 32 on different modes on there so a few versions I've been in the top 40 worldwide, it's a game very underrated from a competitive standpoint compared to say Tetris which has way more tourneys, games and events over the years. I'll take on anyone though still on the 3DS version! They need to make a switch version with up to 4 player offline and online!

[@SebastianGMSFB]

I don't know why Dr. Mario 64 was sprite-based, but it's graphics definitely fit well on the GBA.

[@edisonnnnnnnnnnnnnnnnnnnn6238]

wow i didn't know mario sell drugs for 30 years

[@ismaelgonzalez1456]

Those are pills

[@K3vM16]

@usertheloset I hope he's not going to be in the video and shut up

[@K3vM16]

@@ismaelgonzalez1456 you mean medicine pills?

[@Cyberbrickmaster1986]

Dr. Mario is not a certified practitioner. He only throws pills in a test tube. Miyamoto himself stated that he would never let Mario perform an operation on him.

[@edisonnnnnnnnnnnnnnnnnnnn6238]

@@Cyberbrickmaster1986nice

[@Alexis_-uy6se]

Q buenos videos :3 se ganan mi like. :D

[@Salmedix02]

Very good video topic

[@kenwheeler3637]

The ghost image of where the pill will land in some of the later versions is more of a hindrance than an improvement.

[@kenwheeler3637]

@Diskun That's good. It would be fine as an option, just not as a default feature.

[@user-cy6cn1ff8s]

4:49 サテラビューにドクターマリオあったんだ

[@onyinyeezeasor7462]

22:11 Dr Mario World (iOS/Android) is my favourite out of all of it even it may be on phone

[@kirstenkees755]

Interesting… I like it :)

[@yahiraleman6140]

Nunca olvidaré este. Clasicsso

[@onyinyeezeasor7462]

14:43 16:38 21:39

[@theone9207]

Can’t believe they kept using the exact same version of the Dr. Mario song from the N64 game for almost 20 years

[@EmeraldoTheDragon]

With all these bonus clips, I'm suprised the Virus Buster mini-game from the second Brain Training title wasn't included. It's essentially Dr. Mario in all but name.

[@wingedcatgirl]

14:13 "We've made it so you can never play Classic Mode. We are introducing Sick Mode."

[@mayonayo2016]

nes dr mario fever and melee's version of it will forever be my favorite versions of the theme

[@SgvSth]

Give Dr. Mario 64 the control style of later games (Dr. Luigi) and it is the best by a mile.

[@Windows-rx7qn]

Oldest to newest 0:05 Gameboy 1:01 Nes 2:02 Arcade Play choice 10 2:50 Arcade 3:51 Snes 4:44 Satellaview 5:51 Snes Japan Release 8:26 N64 9:47 Gamecube 6:36 GBA Classic Nes Series 7:37 GBA 10:48 Nintendo Dsi 11:43 Wii Dr Mario & Germ Buster 12:51 Wii Dr Mario Online 14:13 Wii u Classic Mode 15:34 Wii u Operation L Mode 16:20 Nintendo 3ds Classic Mode 17:48 Nintendo 3ds Miracle Cure Mode 21:28 Nintendo 3ds Dr Luigi Mode 22:11 Ios and android Dr Mario World

[@yulianasellyca4001]

Currently, Dr.Mario World now server terminated at this November

[@gisellerivas45]

Dr Mario 64 best one

[@mackenziewachter2508]

I really liked Dr. Mario World back in 2019, but then stopped playing before it went dead. Rest in spaghetti! Never forgetti!

[@Amanda-pz3se]

NES Dr. Mario was and still is my favorite.

[@jaya_surya_a5118]

Back in days.. Default theme in dr mario is heart touching

[@lordmaximus780]

I find I play the SNES version and Dr Luigi on Wii U the most, but all are awesome. Although the Gameboy one has the biggest flaw.

[@bland9876]

What's the flaw?

[@lordmaximus780]

@@bland9876 the lack of colour. Its no deal breaker though.

[@bland9876]

@@lordmaximus780 oh my brain is being strange I was thinkink he had to mean the GBA version. It does have the most annoying sound for moving the pills.

[@theblode1337]

i had the arcade one on a MAME like 20 years ago, forgot about it until i saw that upper screen

[@trentfan13loganproductions25]

9:47 Dr. Mario gamecube is just a port of Dr. Mario 64

[@MoltoRubato88]

What, no Dr. Amigo? 😂

[@Nuggettimegaming]

Lololol 😂🤣

[@dayanemenezes300]

Or Dr. Hello?

[@rubengivoni961]

NO, THIS DR. MARIO

[@Gigabyte1002]

I never knew the Gameboy version was the first release of this. Interesting!

[@OhSayWhatIsTruth]

The NES and Game Boy versions were released on the same day, though if I'm not mistaken the NES one was developed earlier

[@SquidPartyDude]

7:38 WHAT. HOW. I. WOULD. EXPECT. THIS. FOR. A. SWITCH. GAME.

[@shefasadiqalaidaroos7126]

RIP Dr. Mario World (2019-2021) 😢

[@Youtuber-xi6qo]

Whaat? I thought the NES version was the first Dr. Mario Ever! Turns out the Game Boy Version Is first?

[@yannatoko9898]

They both came out on the same day in Japan.

[@just_some_greek_dude]

Dr Mario 64 is underated it had 4 player battle and a story mode with original characters

[@therealzonkertonmczonkz]

how is nobody talkin bout this guy's doctor mario skills

[@arifsudibyo3931]

2:02 Hey Nintendo DS in the 90s!

[@baldingfox77558]

you comment. i reply. WELL WELL WELL. HOW THE TURN TABLES

[@ADeeSHUPA]

@@baldingfox77558 Indonesian

[@ADeeSHUPA]

@рандомный канал mK

[@Angultra]

Crazy how the GB music is almost as good as the NES version. And both have the best music from all the ports

[@I_TheNightWolf_I]

Dr. Mario Express goves really good memories

[@ramondantasoliveira7712]

A versão do NES é minha favorita.

[@thedigweeds9233]

'stage clear, try next' Great English

[@Blocky569]

For The Gameboy The Fever Music Still Good

[@pakganern4491]

6:26 *COOLEST MOMENT EVER*

[@saulgarcia2750]

Me quedo con Dr Mario Nes, Snes y 64 uff :3

[@dr.mystiaraul2826]

Awesome games of Dr Mario

[@mohae65]

The very first Gameboy (1990) version rules!

[@kirkjerk]

Why is N64 the only version with head to head 4 players mode....

[@marektchakourte203]

I didn't play Dr mario 64

[@pabloricardo345]

Brasil 🇧🇷 estou esperando um jogo do dr mario pro Nintendo Switch. Depois do dr mario 64 que é o único que tem multiplayer de 4 jogadores, os outros jogos parece que só focaram nos gráficos. Queremos multiplayer igual ao do N64!!!!

[@vittosphonecollection4134]

I mean Dr Mario 4 players is... Meh, I prefer 2 players. At least me.

[@kirkjerk]

It deserves its place as a mode. It’s definitely better and more serious than 4 players working in one board, which was introduced with the Wii version to show off the wiimote

[@vittosphonecollection4134]

@@kirkjerk Yes, that's true but I think it should stay with 2. The Wii ver would be too easy with 4 players and I didn't even know that was possible!

[@user-bh4uu6we6y]

My favourite dr mario online

[@wabai_879]

The nes is my favorite version of dr.mario and one of my all time favorites

[@Izhen_UwU]

They should make a new Dr.mario for nintendo switch.

[@sky-fw2yy]

this brings back memories of when i would go to my aunts house and play against her in the NES version… was my favorite thing to do

[@skorisu12]

「ドクター、患者さんですよ」 「なに！？わかった。診察しましょう」 「ゴホゴホ、すみませーん、ちょっと風邪ひいたみたいで」 「ほう、風邪ですか」　カチンコチン 「？？………あの、あなた、お医者さんなんですよね？」 「ハイ、ですが専門はウイルス退治なもんで、患者さんを診るのはこれが初めてです!!」 「どうもお世話になりました」

[@steveairport]

Please allow me to throw these giant pills at your head. I am an expert.

[@DoomKid]

Dr. Mario for Master System (Dr. Hello, AKA Dr. HellNo) would have been funny to include as a joke

[@user-kj5re8uf4k]

I like it when you finish the finest music.

[@brittanybradley191]

Dr Mario world is my favorite version I have not heard of it before😅

[@user-gd5cj2ub9i]

My Favorite Version NES

[@Mr-7001]

Dr Mario express is so nostalgic to me

[@MarcusFigueras]

I'm surprised you didn't include the germ busters mode from BrainAge

[@kwbalance108]

Dr. Mario Online...I miss playing that against people all over the world!

[@joey5745]

Same, fun times,

[@jaywitter48]

Love it

[@maricthehedgehog]

3DS is my favorite because it refined the series like Tetris by introducing some new modes while being modern Although the NES one is a classic

[@tokyohanamura]

Kinda surprised the Brain Age ones weren’t a bonus

[@richardespinoza2839]

Ikr

[@damarfadlan9251]

The DR. MARIO in NES and SNES are unsurprisingly amazing for its time in terms of gameplay.

[@timiishola2950]

Tetris & Dr Mario - Super Nintendo Entertainment System (1994)

[@leeclarke6721]

Dr Mario video published on the 1 year anniversary of the first covid patient 🤣

[@SketchieProductions231]

I really wish for the 3DS ports of the games that was by play choice, they had the bottom screen be the play choice description and the top being the actual game

[@virtualboy2558]

While I am a fan of Dr. Mario and love the gameplay, I felt that after the N64 version, it saddens me that they practically stopped making new renditions of the songs, or new songs at all (minus Dr. Luigi). It pretty much became copy and paste after that point with the music. Also that much of the visuals, like Dr. Mario spinning on his heel after every stage, are lifted whole cloth from the N64 version. I know... it's Dr. Mario, and it shouldn't be complicated with high-end graphics or orchestrated songs. We come for the gameplay, pure and simple. But it would be nice to make it stand out a little better to all the other releases and feel a little more excitement like "Ooh, that new Dr. Mario looks and sounds cool to me! I'll go buy it!", than to be "Alright... let's port all the same exact assets into the next Nintendo console...".

[@Jbgfesckkjvjekkwmbzbsbbux]

Retromantra Satellaview Derken Nintendo Bs-x mi demek istiyorsun?

[@jstnrgrs]

Online Rx (wii) was the best version. Online play was great. I hope they bring that back sometime.

[@stringbeanvonsexy5389]

This guy has the satelaveiw for the Japanese snes wow that thing is pretty rare

[@MaskedGuyCh]

Emulation

[@macotela]

You miss Dr. Wario from Wario Ware Inc.

[@Chdesignssecondo96]

01:01 The NES Version is Surreal. 👏🏼👏🏼👏🏼

[@yellowmarioflexing8626]

Without Dr. Mario 64, Dr. Mario would not be in Melee

[@sangbeta2043]

Before I got a game boy, I played a lot of the NES. For the highest level, the GB version is more difficult because the lower resolution screen means the playfield is only 8X15 instead of 8X16 on the NES, meaning when the pills are stacked 12 high from the start you have only 3 empty rows at the top to work with. The GBA Dr. Mario / Puzzle League version in only 8X13. GBA has the screen res, so why?

[@r-l1214]

EXCUSE YOU, ARE YOU OFFENDING THE GBA? HOW DARE YOU!!!!!!!!!!!

[@r-l1214]

😡🤬🤬😖

[@nahumrosario.venezuela]

@@r-l1214 IF you knwo that was you you are that played too many gba games: i played dr mario nes on the different console called Sup

[@Vini_Kirby_club]

Doctor mario in black and white *nice*

[@foxsky4336]

Docteur réparation ( robotique ) :)

[@timoheinonen9570]

Should have included ZX Spectrum homebrew version, as its is very good.

[@phil6508]

I've played dr mario in my dsi in 2009 - 2013

[@vittosphonecollection4134]

I have NES, SNES, GBA, Wii, DSi and World. I've played 3DS but I didn't like it very much. And I have an Atari 8-Bit homebrew version, which is my favorite of the old games!

[@rockymtnsteeze1815]

I play the android one everyday. It is my favorite. The nes one is the first one I played.

[@lovinglife8854]

You forgot about the Nes Remix versions.

[@timiishola2950]

Dr Mario Nintendo Puzzle Collection - GameCube (2003)

[@supp3rguto]

So... the 3DS version (Miracle Cure) is the DR Luigi Wii U version, with Mario??

[@user-fj1hn2ci2x]

Still ‏classic one on the top

[@PKMNwww411_MkII]

Game Boy, NES, 2 Arcade versions, 3 SNES versions (1 in USA and Europe, 2 in Japan [Satellaview, Nintendo Power], 2 GBA versions, N64, GameCube, DSi, Wii, Wii U, 3DS, Mobile

[@brookehenrich8727]

Game: try’s to make him lose me: real life dr Mario.

[@Kembi_Mekemo]

The nes version was first actually since the game was originally called “Virus”

[@timiishola2950]

Dr Mario & Germ Buster - Wii (2008)