Drug-induced lupus. From historical case reports to big data

Drug-induced lupus (DIL) is an idiosyncratic side effect of treatments in which symptoms overlap with those of systemic lupus erythematosus (SLE). The spectrum of DIL constantly evolves with that of the pharmacopoeia. In this webinar you could find the current nosology of DIL, the definition for DIL, the epidemiology of DIL, the clinical and auto-antibody profile, and a small overview on the list of drugs, the pathogenesis, the treatment and prognosis.
More info about SLE can be found here: reconnet.ern-n...
Speaker:
Prof. Arnaud is full professor of Rheumatology at the Department of Rheumatology, University Hospitals of Strasbourg and French National Reference Center for Rare Auto-immune disease.
Following a MD degree from Université Pierre et Marie Curie (Paris) and a PhD in immunology at the same institution, Prof. Arnaud completed a fellowship program with a specialization in auto-immune diseases at Hôpital Pitié-Salpêtrière in Paris. He then pursued post-doctoral clinical research on systemic lupus at the Karolinska Institutet (Stockholm, Sweden) and was subsequently appointed full Professor of Medicine at Strasbourg University School of Medicine. His main research interests focus around the systematic evaluation of treatments for systemic diseases, with a specialization for the care of patients with lupus erythematosus and relapsing polychondritis. With his team, he has contributed to more than 150 research projects in the field of rare diseases. Prof. Arnaud is an active member of the French National Reference Center for Rare Autoimmune Diseases of Strasbourg, of the ERN ReCONNET and ERN RITA, and is the curator of a twitter account dedicated to SLE @Lupusreference

[@matthewcuomo421]

Amazing summary of important information for anyone interested in knowing more about this topic. Thank you so much

[@ERNReCONNET]

Thanks to you for your nice comment, glad to know it has been helpful.

[@mousaalbalwi227]

Dr Arnaud is one of my favorites Rheumatologist. This lecture is very helpful and informative. Thank you!

[@ERNReCONNET]

Thank you for your kind comment.

[@karlint39]

My patient had DIL which presented as pleural effusion after 18 years on etanercept for RA. Treatment is ongoing, so it may turn out that it was spontaneous SLE afterall, but many of the lab results followed the pattern of TNF-alpha blocker-induced DIL. The information presented here is incredibly useful for distinguishing between SLE and DIL. Super helpful.

[@dianejacobd6602]

I was just diagnosed. Not offered any treatment. Joints are so painful. ANA and SCL-70 positive. I am currently waiting to see a rheumatologist.

[@yakubuyakubu509]

Helping me get rid of my Lupus infection is what I will never forget in my whole life #drogoh. You're welcome to my family, thanks for saving my life .💛

[@ERNReCONNET]

Thank you for your comment.

[@bigdawgz4530]

I wish you had included a link to the list of 70 drugs. It's so impossibly small in the video that I can't see if any of them apply to me. I've found only ONE source that implicates Levothyroxine in DIL but what am I supposed to do? How else am I supposed to treat my Hashimoto's?

[@Intwodeep902]

Great video is there any link between drug-induced lupus with the prescription Effexor gabapentin and amoxicillin?

[@comfortenenche3210]

Meeting Dr Edos on KZbin has really been one of the best day of my life after years of suffering I have been finally cured from lupus thanks doc God bless you for saving lives I recommend #Dredos as one of the best for you all

[@comfortenenche3210]

Meeting Dr Edos on KZbin has really been one of the best day of my life after years of suffering I have been finally cured from lupus thanks doc God bless you for saving lives I recommend #Dredos as one of the best for you all

[@ERNReCONNET]

Thanks to you for your kind comment.

[@gloriabrill]

Anyone get DIL after vaccines?

[@771blahblah]

i asked this question and always got a no answer…. i am not convinced.

[@boomchicaboomboom]

I think I have gotten DIL from taking Lisinopril for 6 months.

[@Intwodeep902]

also, is there any link to Epstein bar reactivation from the big C and lupus?

[@cathycharron-folsom4504]

Include metoprolol

[@metriusadams60]

Hydrazaline did this to me after 3 months. I've discontinued this drug. I can barely walk

[@patrickwiredu2318]

Please tell me more. I am also dealing with symptoms of DIL from taking 300mg Hydralazine daily for over three years.

[@tracysmith-yv5lt]

mine is sunlight

[@shecathellraizerme2022]

If you on several drugs that are known to cause DIL how can you find out which is causing it. Hydralazine, clonidine and thyroxine

[@lourias]

I am very sure you are an intelligent person. I disagree with you that to be allergic must be an IgE mediated response. IgG responses are allergenic as well. Furthmore, if you research Mast Cell Activation Syndrome/ Disorder, you will find that the majority reactions that those folks experience are not IgE, yet they experience all that horrible histamine release that the mast cells can produce.

[@SajadMalik-u7s]

Lupus class4 can control for medicine plz give the answer

[@lauralutz4538]

I’m not an MD. This was a waste of my time.