Drugs for Heart Failure

[@inalaura9292]

Not only students, but also pensioners when we are lonely and have nobody to talk to we listen your lectures to know our illnesses to live longer. 60 yo. Thank you that you are. 💐

[@Amanda-cc8iy]

😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊

[@patriciaburman]

❤

[@hellenwallo]

❤😊

[@sarahbouckhuyt538]

Thinking of you ❤

[@annalussier1431]

Teaching cardiology better than any cardiologist we've seen in med school... thank you for making this available to train doctors and healthcare workers around the world! This channel is a gift to humanity!

[@areufkingkiddingme]

Real life and models are very different

[@tewodrosxwubet]

for sure

[@reginaestrada2772]

couldn’t agree more 💯

[@sunsetz2341]

I have no idea how people studied medicine back when there was no internet! If I try to understand these concepts by reading the textbook it'd take me the whole day. While Zach explains it all perfectly in 1-3 hours. I swear I'm actually kinda embarassed of how much I actually never learned properly in the past few years of med school, and just passed my exams by luck. Also, this kind of optimism shifts my perspective on medicine -- when I listen to Zach, I really really try to understand everything for the FUTURE and not just to pass the exam, which is the most important!!

[@manofreedom]

I'm a very busy family medicine doctor with 28 years of ER and urgent care as well as hospitalist service experience and I have to say these Ninja Nerd videos are the BEST teaching videos I have seen. Lot's of deep dive detail that I wish I would have had in medical school, but the internet was just getting up and started in the early 90's when I was in training and residency. This would have been fantastic to have "back in the day." GREAT stuff here.

[@Albert23456]

I'm dealing with stage 3 heart failure and taking several meds...I learned enough to talk to my doctor thank you❤

[@ricknimusiima6571]

“Son of a Gun” is the best online lecturer. Great stuff Nija nerd 👏

[@thekharataykid]

what does that mean asking on behalf of non american people

[@sallieukamara5156]

On behalf of the entire medical students in Sierra Leone, we want to thank you for all you have done for us…Thank you Prof Ninja Nerd ❤

[@sportingene]

Are there many bengali people in your country??just curious

[@aminaqamar50]

I can't listen to any other person having 3 hours of lectures but it's only youuuuuu to whom I can listen 😭

[@lucamirea135]

In the name of all the romanian medical students i would like to thank you. We have our residency exam in two weeks and this topic is a very big one in our bibliography and a very troublesome one, may I add. This will come in real handy. Thank you!

[@yellowindian5134]

Indians too

[@reggiepalmer6157]

Scottish too❣

[@عبداللهمحمدقاسمحسن]

Iraqi too

[@nikolamarkovic4845]

serbian too

[@giorgosvlachopoulos1615]

Greek too

[@ednatrepanier]

You are the best lecturer ever! You are very smart nerd ninja! I adore your ability to share your enormous knowledge!!!

[@NickNorland]

I'm trying to comment on all the videos I watch as I'm going through PA school. This man is an amazing instructor and gifted speaker.

[@tube7663]

I AM HABTAMU TEKALIGN FROM ETHIOPIA I AM CLINICAL PHARMACY STUDENT SINCE FIRST YEAR I AM USING YOUR TUTORIAL VIDEO ITS SO SUPPORTIVE NOW I AM ONE OF TOP SCORER THANK YOU BIG BRO NINJA

[@gopikav6524]

Can’t describe in words how much your valuable lecture and your way of teaching is helping me thrive in my medical school

[@mr.ssj3847]

bro, mad respect and props. seriously your videos are great, well researched and I can tell you have spent a lot of time gathering all this info together. from the bottom of my heart. thank you fam!

[@elyastesfamichael6527]

You are really Ninja bro, you make the difficult easy😉.

[@TroyWoods-lu4ch]

These videos are getting helping me through my pharmacy school exams, thank you so much!!!!

[@rubenruiz6250]

I had heart failure with a LVEF below 40%. With Entresto and after a year on it and then discontinuing it, my LVEF was 65%. I've been without the drug for more than a year now and my heart is still perfect. In other words, I've been cured of heart failure thanks to Entresto!

[@hillarywilkins7395]

Entresto has improved my EF from 25% -45% in 6 months and i have been wondering if I will need to keep taking the med if EF returns to normal range - my cardiologist says that’s close enough to normal but I’m hoping fr further improvements at the 12 month marker as the study results showed. Good to know what’s possible thanks👍👍👍

[@thabelongwenya4666]

Please help. I have heart failure and i do not know what to do because I am always weak and fatigued. I cannot even do nothing by sit still and lie down all day. I feel so hopeless and painful body.

[@yachiapatel]

This dude have taught me not only medicine but also, what commitment actually means. Huge and massive respect buddy for your time and commendable efforts.🙌 Can't imagine how you gather all the information from various literatures and put them altogether within just a week that too in a 3-hour video ✌ Tons of love and appreciation to you and your team 🙌❤ please keep doing 🌠

[@faisalmehedi2490]

Medical lectures owe you a lot..You are a boss man..

[@mariamadenola6534]

I am starting a cardiology posting and all I can say is thank you very much for what you do.

[@noormamoon8920]

From all different countries, we support you, love you, and wish all best for you

[@esammohammad5978]

Thanks for you bro from my heart, your the the best lecturer in the world. Keep going Greating from sudan 🇸🇩🇸🇩

[@karenmoore2972]

This guy does such an AMAZING job of explaining these concepts!! I hope he continues to teach bc many are not able to explain complex mechanisms this well, making it easy to hold our attention in my opinion!! His pace of speaking is just perfect!, easy to keep up with & definitely not dull & boring!! Thank you!!

[@sibuleleshude3366]

One of the best teachers in the world 🌎 ❤ I'm learning a lot from your lectures. Keep it up guys, your work is highly appreciated All the way from South 🇿🇦 ❤

[@garrettross9999]

EMT-b and nursing student here. Thank you. I believe I have a better and more in depth understanding of the material than any of my peers now.

[@robynneRN]

I never knew medicine could be this interesting!! BRAVO!

[@aacc8466]

you, your team, your spouse, your dog, your mailman and your mama....IS THE MAN. Thank You for helping out the little guy !!!!!

[@sucedeu]

Teaching like this is a GIFT that this superstar shares with all of us! 👍👍👍

[@MH-yr6bp]

I am not even a physian but in another medical field and enjoy the courses.

[@nanadarkoampem]

This is one of the best educative sites ever visited

[@salvadorhirth2919]

Your videos are so good that I always hit the like before watching. Congratulations on your dedication and knowledge!

[@em8066]

I wish this was published prior to my ICU rotation in PA school, but it's still a great review now. Thanks!

[@JagjeetJuneja]

You are so intelligent, You have such a cool way of explaining things and I absolutely love your board and marker pens. Keep up the good work.

[@janemercado5815]

Just amazing! he is like the Bob Ross of medical teaching!

[@I_am_Anne]

Yes. Exactly. 🤣😂🤣😂 It is funny because it is true.

[@amandavitaglian5859]

so impressed by the depth of your knowledge and how well you are able to explain it. You're a tru master of your craft.

[@teresawalker2294]

An artist with great handwriting! As a layperson, I actually understand the illustrations and can read the handwriting❣️

[@paulbaddoc2470]

Zach Murphy the great 🖤🇸🇸

[@Melaniexb1]

From someone who found Dr Ninja looking for just this subject, your other video on this topic helped me know that my husband was on the correct drugs for his possible class 2 of heart failure. (He had a quintuple bi -pass just just 3 1/2 years before.) Which then lead to the three scheduled tests US of abdomen, CT, and an Echo! All waiting to take place, to help find the cause of his now (some 70 lbs )of Water weight gain in 4 weeks time!

[@abigailtembo5570]

Thank you so much, you are just the best of all. I Pray for more wisdom and long life so that you keep of helping even the new generation to come 🙏🏾🙏🏾

[@MaryVanlandingham-e2k]

This as a phenomenal lecture. I listened to some of your stuff during nursing school and am now studying for PCCN and wow, so helpful. Thank you!

[@tl4340]

1:04:15 Actually, the 2022 AHA/ACC Guideline on heart failure now suggests that ARNi are now first-line RASi in HFrEF, *ahead* of ACEIs and ARBs. ARNi first, then ACEI if ARNi can't be tolerated (or afforded), then ARB if ACEI can't be tolerated (e.g., angioedema, bradykinin cough). This recommendation is different than what you say in here regarding order of priority. Nitpicking aside, this is a *fabulous* teaching video.

[@Vamparina413]

Ah yes coz that was what I was given which is the Entresto when I was diagnosed with CHF last year with reduced EF.

[@pharmacistfayadhaliahmed4111]

For those who are interested in Pharmacology strongly advised I strongly recommend this channel to be followed

[@hansbeukers7725]

I am a 74 year old male with a pacemaker and use anti hypertension drugs. I did not want to use metaprolol because I am still a racing cyclist and I want a high cardiac output for that reason. You told that metaprolol initially lowers the heartrate (and therfore the Cardiac output) but after some time it even increases the cardiac output. That is nice to hear and I wished I knew that earlier. Thank you! Today I use Perindopril, Nifedipine, Xarelto and Jardiance and I feel fine.

[@demetrikasher1237]

Awesome video, I have heart failure and like to review what my meds are doing for me every now and then haha. Losartan, Carvedilol, Warfarin, spironolactone, and a few others in the past. Thanks everyone in the medical field!

[@ngoziemozie9779]

You just dymystified heart failure with low EF. Thank you so very much for this presentation

[@shoukatmirza5014]

Great work. Doctors can easily make their right approach towards patients and diseases. You make it too easy. God bless you for your great work.

[@SortedBody]

Thank you very much for your time and effort producing this learning material. It will help me in my practice and benefit hundreds of my patients.

[@ednatrepanier]

You are the best person ever who can discuss anything you’re asked to do. You have a unique way of explaining everything so we can understand. Pls keep doing your education videos. Plenty of medical staffs are benefiting out of them like me. I love you!!!

[@JodyLeeSchroeder]

literally was asked to do this by my professor today - let''s go ! Cant wait for this video :) Love you ninja nerds

[@katiela972]

wow this is helping me drastically. I am an ICU new grad and this is very helpful! THANK YOU!!!

[@ssdedsst3585]

Add this to pharmacology playlist please I was seeking this a long time

[@brucenome989]

I enjoy all your videos I think I'm ready for medical school now after watching your videos and the way you teach the lecture

[@amanalok4647]

I’m a med tech entrepreneur and you are the reason my company exists ❤

[@alexistremblay3604]

hey, I'm not a medical student or anything but I love genuinely learning about how the body functions, thank you so much for making this knowledge available for free, actually would cost thousands of dollars of books to learn this stuff otherwise. actual chad

[@JETMDS]

Thank you so much for educating patients with their diseases CHF.

[@awalehussein9614]

Thanks you Dr ninjanerd you are best lectural for medical department, we hope next video for pharmacology will be Diabetes mellitus drugs and their classification in best teaching and memory way

[@kusineraunoniebyang6102]

Thank you so much for sharing in more in-depth information on these drugs. I am HFrEF

[@jenispatel1024]

Due respect 🙏 .....!!bow down to u dr Zack🙌🙌🙌🙌

[@Scoob-hb5eb]

Just want to say you have gotten me through nursing school. Used you last semester and got an A when the previous semester I got a C.

[@SuperLittleTyke]

I'm male, 78 (almost) and I was diagnosed with heart failure 4 months ago with an ejection fraction of 25% to 35%. I'm now taking a cocktail of drugs: Entresto, Apixaban, Rosuvastatin, Furosemide, Bisoprolol, Eplerenone, Dapagliflozin and Aspirin. 11 years ago I had a triple CABG and made a full recovery. Three months after the operation I had a follow-up with a cardiologist and had an echocardiogram. The result of that, however, was an EF of 60%, no noticeable valve disease and the heart was pronounced good. In the intervening years I lost a lot of weight by counting calories and I modified my diet considerably with grains, wholemeal bread, lots of fish, including oily fish. What I want to know is how the EF can sink from 60% to as low as 25% in 11 years.

[@salahal-saleh3076]

Just in time! Thank you

[@irame5701]

Zach is a such amazing human being- lovely and talented. ❤️

[@hdskl2150]

This is so awesome. I have a child with chd and its sooooooooo helpful to hear what these meds are doing

[@hiratariq3293]

I am a pharmacy graduate and bro u are good enough hats off to you

[@trudikaye2326]

LOVE his energy for teaching!!!

[@fatimaalarabi5581]

My exam is on the 5th of January And I'm so thankful cos I'm studying pharma from your wonderful channel It's so entertaining to learn it from you zach Thank you so much for your magnificent effort 💗

[@CarolReidCA]

I'm watching again. The signals from the heart to the medulla obligata is by the IXth (9th) cranial nerve, or the glossopharangeal nerve. The Xth (10th) is the vagus never. I had to look it up to be sure, as it had been a while, but hopefully, that's helpful for someone. The carotid sinus baroreceptors are innervated by the carotid sinus nerve branch of the glossopharyngeal nerve. Their stimulation results in heart rate reduction mediated by the vagus nerve. Thanks for your lectures!

[@searching_4_truth.]

I have had this forever, it will or can cause a person to faint which it’s happened to me. No no drugs in my system. That bad thing is the cops put me in hand cuffs , which of course they didn’t find anything and had to let me go. The worse for me was my name was in the newspaper people automatically assumed that I was on drugs,so of course that’s all people think of you when nothing I did was wrong. This embarrassed me and caused my depression and made my anxiety worse. Don’t let this happen to you. I did get tested on my heart and I’ve always had very low blood/pressure, arterierial wouldn’t open and caused my blood to pool . I have always had thickening of my heart wall( a sort of orcardiomyopathy ).

[@thekharataykid]

wow. i d think i would need my book after this. thankyou for helping me engrave this concept in m mind

[@abikim912]

No words... phenomenal lecture. Thank you so much❤❤

[@labs2798]

Great content as always. Easy to understand, easy to revise and learn from. Your videos are a lifeline!

[@annjelasantiago8057]

Thank you for this awesome lecture. Your knowledge and commitment is remarkable.

[@5pmShaun]

You are the bomb! Better lectures than during med school The why’s of pharm!

[@carpe996]

You may be in residency or fellowship training now as I have noticed the decreased number of recent videos BUT I PRAY MY FRIEND that you are working toward a specialty where you will be able to teach at least a large percentage of the time in a medical school, and a medical school that will allow you to continue this work with these videos and on your website because YOU HAVE A SPECIAL GIFT and are helping so many health care professionals and others be better practitioners and better people. YOU HAVE HELPED RESTORE MY LOVE FOR MEDICINE WHICH I HAD GOTTEN AWAY FROM. GOD BLESS YOU MY FRIEND. I know you would be a phenomenonal researcher and clinical practitionerand I PRAY ( selfishly I readily admit 😂) THAT YOU LEAN TOWARD TEACHING ( along w some clinical care to keep you FRESH, of course )

[@BassantMohammed-i6n]

No matter how much i try .. i can't thank u enough

[@yvonnevillalba7722]

Thank you for this detailed explanation. You are a fantastic teacher.

[@unicefox_sharksit109]

NOT ONLY YOU ARE AN AMAZING TEACHER, YOU ARE SO FUNNY TOO

[@joudizawet7573]

Can't imagine studying medicine without your videos! :')❤❤❤

[@EntEmpireTV]

Thanks man , you are a great help to medical students

[@griselgaspar6904]

Amazing video Zack! You have an amazing talent to teach! You make all these concepts so easy to understand!

[@tamngoc6046]

Thank you Ninja Nerd very much!

[@TrishErwin-hu4jo]

Another video on your channel explaining CHF was so clear, informative & helpful - so, thank you..Got anything on APS, Auroimmunity diseases? If one wants to empty a room of medical folks just ask questions about APS , lol (and yes, sometimes that is desirable). Can be difficult to get & understand enough information to make decisions regarding one's health- very frustrating.

[@deepakrtr4840]

Bro...I have no words for these masterpiece.. Greetings fm 🇮🇳

[@duaajawed2273]

Thank you so much for saving my semester! ❤

[@mathiasmontalvo3683]

Thank you for this detailed explanation. It is truly a fantastic video.

[@CarolReidCA]

I just found you. You're an excellent instructor/professor. I'm having to take this in a bit at a time, but excellent teaching, excellent content, and to the point. I hope and pray that you are teaching as many students as possible, as we need tons of clones of you who can learn, and then they can teach others as well, and so on. You have a great voice, you cover the subject matter in an organized manner, you are clear, you have drawings and printing that is great and readable. Can you do a video on Alpha-1 antitrypsin deficiency MZ phenotype, and treatments for lung, liver and eye inflammation, drugs to avoid (such as Tamiflu, NSAIDS, Tylenol, etc.), risks for heart, lung, liver, kidneys, brain, retinas (especially in children), etc.? It seems MZs are more at risk for both lung and liver problems, as well as other problems that have very little research, it seems. This would be greatly appreciated, both from a personal and professional standpoint. Thanks for at least considering this. I agree that Ivabrdine is a strange bird... Wouldn't the ion transfer create a delay in and/or prolongation of ST waves? And all that entails? (Early repolarization, aneurysms, pancreatitis, etc.)??? I'm asking, as it seems that could be a problem, and without other meds, a possible increase in stroke risks??? I can see why they'd need to ideally be maxed on a beta blocker when using Ivabradine. And a

[@KaოA]

When are you coming at India sir???

[@thomascooper6679]

Professor- Please do a similar exposé on how SGLT2 inhibitors work for non-diabetic heart failure patients with low EF (

[@asanglajamir]

Love love love your videos. Please keep posting on more and more new topics

[@arduh]

can you please continue on the cell biology videos, for example, the techniques for monitoring and manipulating cells and genetic material? you are the best teacher ever:)

[@mercyochoa2135]

Your video to this topic is impressive, Brilliant, thank you

[@فيصلفراس-ط5ك]

Greatest man for ever.

[@Vamparina413]

It is interesting you mentioned the Entresto is an alternative because I was diagnosed with CHF with 35% EF and was started on Entresto and BisOPROLOL. I was told that I would be on four type of medication as my first line which is the Entresto, BisOPROLOL, Spironolactone and Empaglifozin. Is this perhaps the new standard for CHF first line?

[@DavidRamirez-lw8lp]

Yes. This lecture, while amazing, is a bit outdated. SGLT-2 inhibitors are now part of GDMT for HF

[@borisy91]

ACE-I and ARBs are not first line for HFpEF. The lecture though is quite good. Also SGLT-2 inh. are first line for HFrEF and HFpEF

[@heinrichnel727]

Best 3 hours ive ever invested in

[@ndukeabasiinyang9421]

Thank you Dr., for this awesome video

[@Yem-Doc]

Thanks Dr ...from Yemen

[@rawaashaar9679]

You deserve to be the hero who save medical students ❤

[@pilotogeta]

Made it easy for me, I really really enjoyed it ❤❤

[@cynpar2922]

great lecture as always. i wish you'd add the sglt2-i and its role in HF to this lecture per the 2022 gdmt. Thank you so much!

[@sudharshikawshalya3733]

I am thankful you to for your interesting teaching methods.great work. I m interested very.

[@mathewskataso8907]

amazing stuff as usual