Dutasteride Stopped My Hair Loss But...

[@letsgethair]

🧪 Join Get Hair Lab - The Science-Backed Shortcut to Hair Regrowth! letsgethair.com/lab

[@emperorscott]

4 years taking Dutasteride 0.5mg daily. I've not had any side effects as far as I'm aware. I'll keep taking it as long as it continues to work. Or at least until they create an even better medication.

[@Twanger..]

What kind of gains did dutasteride give you?

[@capo4ever334]

I’m on 1.5mg daily for 2 years now and was on 1mg fin for 3 prior and I’m good

[@Jaythesparrow]

Same here 👌🏻

[@emperorscott]

@@Twanger.. I was on Finasteride daily for just over 4 years, but I noticed my hair was thinning again slightly around the 3 and 4 year mark, so I decided to switch to Dutasteride which helped regain my hair that was thinning while on Finasteride. Dutasteride is still doing the job 4 years on.

[@Twanger..]

@@emperorscott do you have whacky dreams on it?

[@moredishesmorebishes7044]

I got bad sides on fin but none on dut. Ita fine for different people to tolerate different drugs differently but trying to warn people away from it based on ONE experience is so stupid

[@Aasmrrrelax1]

Exactly 😂

[@RKO1988]

Excellent analysis, more dishes more bishes

[@welfareleech1525]

same

[@LightWeightsBebe]

Me too. Finasteride was a disaster of side effects including brain fog, shit mood, zero libido and no reduction in hairloss. Dutasteride has been a miracle, hairloss stopped and libido through the roof

[@brizexbrizex]

so he had side effects and they went away after some time, where is the issue here ? literature showed this exact same case where side effects subside with use and its completely normal. when it comes to dht, the hormone is very very very important for teenagers between 10 and 19 years of age once your primary and secondary male features fully develop, dht is literally useless and only functions to boost your prostate size and give male pattern baldness

[@davidomeara4704]

DHT is not a useless hormone.

[@brizexbrizex]

@@davidomeara4704 okey sure, can you elaborate on your claim then ? Any science behind it ? What does dht do then when its not so useless?

[@capo4ever334]

@@davidomeara4704post puberty it certainly is. Ask mtf

[@lorenzosomma6007]

⁠@@davidomeara4704it is after you’ve reached puberty

[@TheHairChemist]

​@@davidomeara4704exactly, the references are in the description for people to read more on this. It's a very interesting side of hair restoration medication that warrants discussion.

[@Luckyluckyluc]

I can't agree with that blanket statement that DHT is important post puberty. There is no concrete evidence supporting that claim. Arguing that we would stop producing it if we didn't need it doesn't work. There are a lot of things happening in our body that surve no purpose. Take a look at hairloss in and of itself; what is its use? Still, it happens to about 80% of men...

[@MattThe1in27-1Hamill]

Agreed. Our body produces cancer cells every day. Does that mean cancer is good?

[@Jaythesparrow]

Exactly.

[@nboss968]

I have been taking Dutasteride for 8 months and have actually regrown hair with no side effects.

[@wasteman3259]

@@nboss968lucky shit

[@RedBar3D]

Another example is the appendix. People do quite fine without it. EDIT: I'm not saying DHT is useless after puberty. I don't know if it is. I'm just saying that there are plenty of examples of things which are dispensable, but that, all the same, evolution has not gotten rid of.

[@FlavioMarceloSousa35]

I took fin for 20 years, it stopped working in 2020, changed to dut and I'm doing great.

[@letsgethair]

great to hear!

[@jazzskunk91]

That's quite a long time being on finasteride, good to hear dutasteride is working even better. I've been on finasteride for about 8 years now and I've tried switching to dutasteride, two instances all the way up to a year, but I get frontal recession and even crown loss. I'm wondering if I should keep on with dutasteride past a year to wait for improvement? Finasteride seems like it works faster and better with less shedding at the year mark. It really sucks being on dutasteride up to a year and areas seeming more sparse. Could it really take longer than a year for miniturized hairs to grow back stronger?

[@TheMatrixgod]

@@jazzskunk91 it takes a year for fin to work?

[@yourbrain8700]

I actually have less side effects on dutasteride than finasteride. There are definitely people like that out there.

[@frankieb9777]

Same

[@Frusciante.Flea.]

Same here. And I've had the same sides he had when trying Finasteride instead.

[@stevejhkhfda]

I heard this a lot. I will try it low dose topical...

[@yourbrain8700]

@@stevejhkhfda With topical I had close to no side effects, but also very little efficacy. I needed to use 10-20mg topically to get a decent-ish effect. Very little penetrates, it seems. Currently, I'm using 0.05mg orally, and that is way more potent than 10-20mg topically, I'm starting to regrow my juvenile hairline. However, I am noticing a decrease in libido and erectile quality (which can be made up for by PDE5 inhibitors). High dose topical dut combined with pyrilutamide was good enough for me to maintain, but not regrow. 0.05mg dut has given me more regrowth than oral fin, with less hit to sexual function. However, the hit to sexual function is still meaningful. Still, I think low doses of oral dut may very well be better tolerated than normal doses of oral fin, with comparable or better efficacy. Topical dut, on the other hand, IME, is a very weak treatment, and you need to use tons for it to be meaningful. I was doing 2% dut by Parati, might go back to it, might stick to oral, not sure yet.

[@conandoyle1740]

@@yourbrain8700 how do you dose 0.05 dut oral ? Tiny dose

[@mikew2911]

Been on dutasteride for 7 years, froze my hairloss.

[@unclechaelsneckvein]

@@mikew2911 Did you try finasteride before going with dutasteride or went straight for the kitchen sink?

[@mikew2911]

@unclechaelsneckvein Fin first. Worked good for about 2 years then out of no where I started rapidly losing grown and thinning. Dut has lowered my libido a little but I'm happy I switched

[@unclechaelsneckvein]

@@mikew2911 Thanks for the answer, happy it works for you 👍

[@deanhorn2369]

Im 22 and just started dut it scares me a bit but I hope it improves my density.

[@unclechaelsneckvein]

@@mikew2911 Thanks for the answer 👍

[@user-vh2us8co6b]

Not a fan of this at all… dutasteride is dose dependent and studies show that 0.5mg every 5 days is around equivalent to 1mg finasteride daily, and reduces around the same amount of DHT. On Kilian’s channel he likes to boast how finasteride has been a wonder drug for him, yet here he is slating dutasteride because of a minor side effect that went away with continued use. Many people experience side effects with finasteride just as they do dutasteride (with there being an increasing consensus that the incidence is similar). It’s quite clear from this that he would have a similarly negative view to finasteride if he was unfortunate enough to experience side effects from it. Where is the balance?

[@exactly1176]

The HairChemist is not about fact. He even has a biase toward oral minoxidil which is in fact (by far) the most dangerous drug of all. Couldn't agree more with you about dutasteride

[@Frusciante.Flea.]

Totally agree, I had these side effects on Finasteride but funny enough not on dutasteride, but here we are saying dutasteride is so much worse for you cause of his experience.

[@legion-t5j]

​@@exactly1176oral minox is not the most dangerous

[@user-vh2us8co6b]

@@exactly1176 I’ve got nothing against him personally, but his mantra very much seems to be that if I a drug worked well for him then everybody should use it, and if not then nobody should use it. Completely agree with oral minoxidil. The fact that we have Killian and certain others on KZbin encouraging people to take upwards of 5mg of oral minoxidil daily (which could literally result in death) is crazy !

[@exactly1176]

​@@legion-t5jit came out as a topical for hairloss for a reason . Scientists are not idiots . Some youtubers on the other hand ...

[@shanghaifunk.]

Easy to say for someone who has the hair of a newborn child. This guy looks like he never had any hair loss in his life.

[@oliverjay1035]

He has had multiple transplants

[@Samfrancis0000]

He’s spent like 100,000 USD in transplants

[@DC-wo2yb]

his hairline is far back, the hair on top is extending like a bridge several inches horizontally in front of it

[@Luckyluckyluc]

@@DC-wo2yb Yeah, looking at the temples from the side you see he had some progression he reversed with transplants

[@legion-t5j]

​@@Samfrancis0000did he mention that?

[@pasta8470]

the dynamic duo returns

[@BARON.SAMEDI.]

..like Batman & Robin of the 60's?!?😉

[@jsaaaaaaaa11]

My experience with dutasteride, side effect-wise, has been so positive that I would even take 2.5 mg if I could obtain that dose. I've never felt better cognitively and physically in my life, and I seriously doubt that DHT would provide me any benefits. As for people who report side effects, the more dramatic they are, the less I believe them-there's probably something else going on with those people.

[@Moral-Medicin]

Wow can’t believe you are denying PFS. I took finasteride and fractured my spine weeks later. I also got really itchy skin. You think that PFS suffers want this condition. I hate you.

[@centauro3974]

The problem here IS that people only thinks that dutasteride and finasteride reduces DHT levels, when 5-alfa-reductase mediates in much other processes, like neurosteroids formation

[@letsgethair]

Correct. Will be covered extensively in one of my next vids

[@velocity1852]

So what does that mean?

[@acquiesce100]

Good to see you both doing a podcast. I have a feeling Kevin is going to do a response video to this.

[@Aasmrrrelax1]

Are you bald?

[@Obez45]

But I don't get it 0.5mg DUT will only remove _50%_ of DHT from the scalp vs FIN's 40% - there is still 50% left of DHT to do it's thing and this would also be similar at other sites in the body that DHT is created. Moreover, isn't serum DHT useless anyway? It's bound up via shbg so it serves no purpose outside the areas it was created. I always saw serum DHT as just “spillage” from the areas that DHT was created so it's not an accurate indication on exactly how much DHT is being inhibited in said areas - it's definitely not 95% decrease. Basically DUT is not getting rid of all DHT in the body - it's practically impossible to do that, it's removing 25% more than FIN.

[@letsgethair]

Dutasteride is definitely not perfect. Neither is Finasteride. They inactivate the whole 5ar enzyme family in more than 20 tissues in your body. Thats more than we need. Micro dosing Fin is in my opinion the best you can do (risk/reward - wise) - especially if you are lucky to start ASAP as soon as you notice first hair loss signs.

[@Charly_dvorak]

2.5mg dut supresses 79% of scalp DHT

[@DTOLL9000]

Finasteride only worked for 2 years for me, I am now losing hair again nearly 4 years in. Dutasteride is my last hope.

[@alcanvart]

what noorwood are you

[@DTOLL9000]

@@alcanvart Nw1 and diffuse thinning, also have retrograde alopecia.

[@Vegas.-]

Hair transplant is the way

[@Twanger..]

I've been taking 0.5 Dutasteride, eight months now. Can't say I've had any noticible side effects, except crazy dreams or nightmares. I've also added 2.5 Oral minoxidil for a month, once again, no noticeable sides.

[@aleksandarstojceski3139]

Every day use? What kind of dreams.

[@Twanger..]

@@aleksandarstojceski3139 shit dreams

[@123ChrisG]

You say look at the research but a meta came out literally stating that after adulthood DHT has no use. Testosterone is far more important for everything including sex drive. And testosterone levels will raise as a result of Dut administration.

[@LaszloGalffy]

its still ismportant as the secondary male sexual hormones. For many people it contributes to healthy sex drive and mental health. Once you swith it off, come the side effects with libifódo troubles, brain fog etc. And i am 100% that its more than just 2% people always mention.

[@123ChrisG]

@@LaszloGalffy I’m sure it’s affecting biology and psychology a tiny little bit, but it’s way over exaggerated. And we know that the majority of those reports are nocebo effect and false reports. And we even have studies showing this to be the case and how strong nocebo effect is. Added to the fact Dutasteride is a much more potent DHT blocker compared with Finasteride yet it has half the side effects. Work that one out? It’s really not something to ever worry about. Fortunately for people who want to save their hair DHT has no real benefits. And you can always stop or lower the dose, just like steroids and aromatise inhibitors DHT blockers are not permanent, PFS itself is made up, it’s literally a nocebo effect there is no scientific basis for it, and if it were true then people wouldn’t need to be taking finasteride permanently because apparently DHT is permanently lowered. People are just whiners. 1. Mondaini N, Gontero P, Giubilei G, et al. Finasteride 5mg and Sexual Side Effects: How Many of these are Related to a Nocebo Phenomenon? The Journal of Sexual Medicine. 2007;4 (6):1708-1712. doi: 10.1111/5.1743-6109.2007.00563.X 2. Tuttle AH, Tohyama S, Ramsay T, et al. Increasing placebo responses over time in U.S. clinical trials of neuropathic pain. PAIN. 2015;156(12):2616-2626. doi:10.1097/ j.pain.0000000000000333 3. Howick J, Webster R, Kirby N, Hood K. Rapid overview of systematic reviews of nocebo effects reported by patients taking placebos in clinical trials. Trials. 2018;19(1):674. doi:10.1186/13063-018-3042-4

[@123ChrisG]

@@LaszloGalffy so from my point of view, based on actual scientific evidence i am 100% that it is much less than 2% and as for secondary male sexual hormones we have data on that too. For example in this study PMCID: PMC3192006NIHMSID: NIHMS291918PMID: 21196939 A role for dihydrotestosterone treatment in older men? We find that DHT does not play a significant role in the normal physiology of adults. The most notable effects are prostate enlargement and male pattern hair loss as they age. There is no real “benefit” or reason to have more DHT in your body. And it’s toxic like all androgens, DHT being the most toxic and damaging is very detrimental to your overall health, especially cardiovascular health long term, it’s also why men get leathery non elastic skin as they age, thats not just sun damage thats DHT as well.

[@123ChrisG]

@@LaszloGalffyno thats bs, studies show it has no effect in adults. Ive posted a load of studies and citations but my comments have been deleted on this channel. The truth is that most of the 1-2% are actually nocebo effect. So in reality it’s probably around 0.75% of people who actually have side effects. And it’s funny because the reported side effects of Dutasteride are less than that of Finasteride yet Dutasteride blocks far more DHT. So yeah it’s all just over exaggerated nonsense. DHT is very toxic like all androgens but testosterone has the ability to convert to estrogen mitigating the damage, DHT is just plain toxic. So If you want leathery skin, CVD and hair loss keep your DHT.

[@123ChrisG]

@@LaszloGalffy well okay do you have any high quality evidence to support your claim? Anecdotes or case studies do not count.

[@VolcardoReviewer]

Fin worked for me for about 2 years. Then I switched to Dut. Thankfully I didn’t get any additional side effects. In fact the sides I got from Fin no longer existed with Dut. Oral min actually gave me sides.

[@DTOLL9000]

Same, fin only worked for about 2 years and now I am losing hair again rapidly, starting dutasteride in a few days.

[@njclem]

I will preface this by saying every person can have varying experiences with these drugs, but the statement that DHT plays a role in cognitive function and glucose control is very limited and far from definitive. If there is new, groundbreaking research that I am unable to find on this topic, please feel free to provide a link.

[@nbvvc-pi6pi]

All this is really confusing to me, i did a blood test months after being on finasteride, my results came back i had low dht, the finasteride did nothing for me, maybe small pain at start but went away, my sex drive went up if anything, i am nw5 i would say, i read up that low dht should not have hairloss, but shouldnt be great for body hair like a beard. Im the opposite i have hair loss, but can grow a full beard. Im thinking of dutasteride! See what happens

[@j-uk2189]

I’ve been on dutasteride for 4 years everyday and never experienced any side effects? I suppose everyone is different. If I apply topical minoxidil, I respond well, but get awful side effects such as shortness of breathe etc.

[@naimhammami4590]

Thanks again for sharing your knowledge and witnesses with us 👍

[@welfareleech1525]

he continued taking DUT as the side effect went away. What's the problem? it states that on the leaflet. Sounds like every medicine there is available.

[@kaisersoze851]

Hey bro! Love your channel. Sorry if this is a bit unrelated, but do you take supplements such as DIM or Ashwagandha currently alongside with Finasteride, or perhaps zinc supplement? I would love a video on this and perhaps ways you balance hormones as much as possible while taking Finasteride

[@ricardorodriguesrr18]

I tried dim with calcium glucanate caused me ED and fin also caused me ED . I'm trying fin at .025 mg. Daily yo see i don't get side effects.

[@newjerseylion4804]

Duasteride is fine when the does is 0.5 mg. But Avodart has 5 mg which way higher. Also topical solution is always an alternative

[@unclechaelsneckvein]

The argument that if it was redundant we'd not have it is absolute BS. DHT is important during puberty. Not after AFAIK. His story is basically that he got side effects, they went away after a few month and then he got scared? (not talking down on him but that's what it seems to me) and stopped. What is the argument against dutasteride again? He says we need it and we should focus on the other effects of the drug not just hair, but what are those?

[@euanjackson811]

Yeah he just used anecdote to say people shouldn’t use it not bit strange. Wonder if he got sides from fin or oral minoxidil would he say the same.

[@letsgethair]

It is not just about DHT guys. With Dutasteride you shut down production of further metabolites - synthesis of which is dependent on 5 alpha reduction. Good example is allopregnonolone - antidepressant having anxiety reducing effects. Another ones: 5α-deoxycorticosterone, 5α-dihydrocortisol, 5α-dihydro-aldosterone and others. Their function I can explain in another video because this video was mainly about sharing Killian's experience. Furthermore, DHT is a paracrine hormone (acts in the tissues). Therefore it does not make sense to lower the DHT more than 90% in your whole body first, in order to get the DHT lowering in the tissues second (scalp in our case). With FIn I am more forgiving, since it leaves 30-40% systemic DHT untouched. Dut is also much better at inhibiting type 2 5AR - which means it is already a more effective version of Fin - even if Dut couldnt inhibit type 1 5AR. Side effects people get from Dut or Fin are not only because of DHT suppression but also likely because of suppressing all of the 5AR dependent hormones and metabolites your body wants to utilize for proper function, otherwise these metabolites woulnt exist. With increasing epidemic of low sperm counts and infertility issues, Dutasteride is a bad choice for anybody who is interested in having kids the quick and easy way in the near future. Btw in the clip he also mentioned a doc who did not want to prescribe Dut to him for health concerns so he had to find a different doc.

[@unclechaelsneckvein]

@@letsgethair I would love a Haircafe-styled detailed video about this as I don't know too much about the details of how dutasteride works and the details of the potential side effects (I only know of those it shares with finasteride). But I think there should be data to support any such claims since dutasteride has been out there for a long time and I'm sure there are studies about any negative effects it can have. It makes sense that this video is not about the details of dutasteride (but part of a conversation with a guest), I was just taken aback a little by the lack of precise claims or anything backing them up. Saying dutasteride MUST be dangerous based on how it works is very different from saying it IS dangerous because we know of cases, etc. So I'd love a follow up video where you share your knowledge about this topic.

[@letsgethair]

​@@unclechaelsneckvein I will share more on this in one of my upcoming videos so you get a better picture.

[@unclechaelsneckvein]

@@letsgethair Thanks dude!

[@DinoSpumoni-rn3of]

Where is this full conversation? Interested to listen to the whole thing

[@vipGamerONE]

Thanks for this interview 🤩👍🏻 Personally I use Fin 0.5 it's working great plus derma roller 1 weekly with ketoconazole shampoo twice weekly 👍🏻

[@BlockStabFatality]

So you had no sides on Finasteride, but you had sides on Dutasteride. Therefore DHT must be this very important hormone in adults and people should stay away. Amazingly narrow perspective.

[@harshmishra8701]

I am getting rashes with itching from finasteride. Should I switch to dutasteride?

[@velocity1852]

Yes if you get any side effects on finasteride you should probably definitely stop it.

[@velocity1852]

But more importantly talk to a dermatologist you feel you can trust

[@SDMotorsports]

Always hating on dut, this lad

[@Jaythesparrow]

It’s a shame really, probably annoyed that he got sides from it or something

[@acquiesce100]

People also have to realise that he works for his hair transplant surgeon and his surgeon needs leads in what is now becoming an ever increasing competitive market for surgeons.

[@omarion07]

I had low libido, erection problems and couldn’t lift as heavy few weeks after starting dutasteride. The side effects are there.

[@mattsvoid]

@@omarion07I’ve never had a girlfriend so the side effects don’t really scare me

[@bennybenny7382]

is topical FIN 0.1% better than oral fin at reducing systemic effects? I want to minimize side effects, I know manual company has 0.1% topical fin

[@letsgethair]

0.1% has a pretty solid systemic DHT suppression. Look up the studies form Casserini et al. Should be a bit better than oral Fin 1mg but not by much. 0.025% is better for sure when it comes to safety but the efficacy will suffer. I tried switchiing from 0.5mg a day onto 0.025% a day for 14 months and lost ground.

[@Vakator-29]

So only some get sides because we all have different levels of dht and a specific % to function properly? Seems hairloss is case by case then and a cure for all seems almost impossible 🤔. And why does dht cause hairloss in the first place? Our hair is fine and then all of a sudden dht becomes a problem it seems like. Is it just poor genetics? But then it would seem a majority of men have poor genetics since hair loss is a huge issue.i also womder if there are things that can activate dht hairloss? Like stress, if stress increases dht then could you start experiencing hair loss that you think is stress related but is actually dht related meaning that your dht levels were fine but then stress raised your dht too high amd now you have hair loss? But now that you have dht hair loss the only thing that will help is a dht blocker? Its like something activated in your body and now dht is a lifelong issue? Is this more abt dht or more abt our hair follicles? So maybe our genetic issues aren't because of dht but because of the follicles being weak? And what abt only some hair falling out? This seems to prove that its a follicle issue and not dht since we dont lose all of our hair at once. Do we even know why dht causes hair to stop growing in the first place? Why cant we just make the follicles stronger instead of blocking dht?

[@BashLoGiudice]

This dude looks good bald and with hair Enjoy your lives fam

[@commenton1]

"I don't want this model hairline anymore" says no one ever 😂

[@conandoyle1740]

Anyone here on the fence looking to test Dutasteride right away ? I think I will hop straight on, pull through even with sides until they go away. Just having to find the correct dose now

[@EliteRamon]

Dont do it. it gave me terrible side effects snd im stuck with them for 5 months

[@conandoyle1740]

@@EliteRamon try sodium valproate + mesterolone or hcg.

[@kevinlimpert8523]

True story for me in 2020 when I got serious about trying to get hair back I first thought by getting stem cell injections that would be the is all end all .when the doctor told me what to expect I just went all in and pretty much threw the kitchen sink at it .hair Cafe was one of my influences as well as Killian with the oral minoxidil as I still keep using today .I was taking both finasteride and dutasteride on alternating days .I never gotten any shed from anything, probably didn't have anymore to loose as I was a Norwood 6 for over twenty years and my transplants were also thinning out .all I experienced was a slow gradual hair growth .I dropped using dutasteride after my 2.5 year mark and no drop off .however I been doing my own experimenting with injecting vertiprofin in my scalp and found that to be a game changer .I still keep getting more gains from minoxidil and finasteride even after the 3 3/4 mark .I think vertiprofin does more than just grow hair in the future donor sites I believe it reverses fibrosis

[@aleksandarstojceski3139]

Where do you get if from?

[@Samfrancis0000]

Sorry, thehairchemist, but not all of us can afford to drop 100,000 USD on hair transplants. For many of us aggressive medical therapy is the only affordable option

[@VolodymyrPankov]

After hair transplant without the same chemical therapy the hair will die, because DHT.

[@Jaythesparrow]

100,000 USD 😂😂 a bit much buddy

[@Freakazoid23]

i just paid for mine and i paid 2k. i get it done in 3 months and the only thing i have to pay besides the surgery is the flight. so i pay 2.5k for the whole thing. people spend more on laptops…

[@legion-t5j]

​@@Freakazoid23 And ur donor is likely butchered

[@naimhammami4590]

@@Jaythesparrow yes too much buddy . I was a NW 6 at 37 year and did 2 succesfull hairtransplants in Turkey and im completely rebirthed .Its not me that state it but people just didnt believe ...anyway what i want to say is for approx between 5k and 6k you can comeback . Just dont go to hairmills for 1000 euro . If somebody wants piocturs from before/after i'll send you on email.Of course i'am on Finasteride 1.25mg daily .I start it by microdosing and upped 1 by 1 ... I hope this give you a better idea about hairtransplants . So your 100.000 USD bro 🤣

[@Maverick-Ascendant]

I feel like same dutasteride is not working for my hair but finasteride does ,! .

[@Qwxiq]

So blocking an important hormone like dht became normal? I cant believe that bc if you take medications to block other hormones like dopamine or insulin you cant just get away with it you’ll have side effect for sure! I need to understand this

[@DTOLL9000]

Apparently your test rises more on dut than fin so that could be causing you more hair loss.

[@Moral-Medicin]

@@Qwxiqexactly bro. Finasteride has literally killed people. They don’t talk about how it will kill you at certain doses.

[@spearfish]

I had way worse side effects on fin than I do on dut

[@Moral-Medicin]

PFS is real. I got it and transferred it to my brother.

[@verivillon]

Incest moment

[@capo4ever334]

That downlighting is brutal on your hairline bro. I’d think about switching it up

[@letsgethair]

yeah haha. I dont care to be honest. I'd care if it looked like it 24/7 but we all know it doesnt.

[@Aasmrrrelax1]

He should switch up fr 😂

[@richp6716]

This guy is unaware of evolutionary timeframes? Ask him about his recurrent laryngeal nerve

[@Gibonz]

2.5mg dut ED master race checking in 👋

[@rgowlikar1]

you should get Alex from hair regrowth with alex on your show

[@a.karatas953]

DHT is necessary to produce Testosterone. The Body recycles DHT to testosterone. So, if you reduce DHT, you reduce by time your testosterone.

[@mattsvoid]

trt bro

[@amaretsu6053]

That logic doesnt nake sense. If you never produced dht in thr first place you wouodnt need to recycle because you kept the spare testerone

[@a.karatas953]

@@amaretsu6053 yes, you are right i missunderstood that. The body converts 10 % of free Testosterone to DHT. DHT is more potent for sexdrive, muscle growth and energy than Teststosterone. But if DHT does not effects Testosterone, why my Testosterone levels decreased rom a good level to a low level only by reducing DHT with Finasteride? Why did my moring erections stopped with DHT-blockers? I think, the body also needs DHT to produce Testosterone in a way of a recycle procedure?? Aftr stopping DHT-Blockers, my Testosterone increased again.

[@Qwxiq]

@@amaretsu6053you just figured this out in you brain, human body dont work like that

[@amaretsu6053]

@@Qwxiq DHT is only a paracrine hormone , not an endocrine hormone like testosterone. It's only made in the places where it has an effect, aka it's only made where you find 5AR enzymes which are scalp and prostate and those are the main target issues where DHT acts. Testosterone on the other hand is made in the testes and then it's sent out in the blood where it has an overall effect on the body and brain. Testosterone is NEVER EVER made from DHT😂. The reason why DHT never needs to be recycled or anything is because it's only made and targeted LOCALLY. It's a paracrine hormone. The Brain doesn't care if there is too much DHT in the scalp !! Your brain don't care if you go bald , in fact your brain doesn't even know it's going bald because DHT levels are affected by 5AR enzymes that are existing in skin and scalp and prostate! But the brain does care if there is too much testosterone because it's an endocrine hormone ! So it will decrease testosterone production if there is too much, e.g. when you're taking steroids

[@pierop96]

I don't understand if he took topical Dutasteride or pill.

[@exactly1176]

Pill

[@Twanger..]

Could I run the Oral minoxidil perhaps alone, and hope for decent gains?

[@akilbarboni4198]

No, you will have like a year or two success, but eventually hairloss will catch on. You need to be on either fin or dut for long term success.

[@Twanger..]

@@akilbarboni4198 Hmm, trouble is i get Avodart easily prescribed here in the UK, and the temptation is to carry on with it. It does scare me somewhat, but so far I feel OK, just don't have any or very little crown regrowth thus far to make it worthwhile.

[@TricksterLawlet]

Nope because you're not stopping the root cause of androgenic alopecia

[@Qwxiq]

@@TricksterLawletinstead of taking dht blocker and destroy our manhood why not just make a medicine to stenght and protect those follicles from getting impaced by the hormone?

[@PacificVoyager660]

Oral min has the worst side effects. If you are afraid of fin/dut's side effects I wouldn't touch oral min at all.

[@Aionjimme]

3 years a lot of shedding with fin, like every month… (i think because of the half life). Now 6 years 0.5mg dut daily and rarely shed. Less interested in sexual things but that’s not a bad thing. Still interested enough for sure.

[@pandacalvin9561]

I had bad side effect even with finastrate. I became more touchy and get teary easily. So i stop for a month and now i try again for .25 every second day. I still get a bit touchy. Unsure it is really for me.

[@Aasmrrrelax1]

Bro WTH just stop taking it if you gonna micro dose that badly 😂

[@acquiesce100]

Talk to your Dr's instead of Dr KZbinrs. And do your research to find a DR who is understanding and empathetic and has a vast amount experience in these drugs as well as treating hair loss with both Fin and Dutasteride. Stop looking for Dr KZbinrs who also have a vested interest in getting leads for their surgeons they work with.

[@cooley685]

I suffered sexual side affects using finasteride

[@Qwxiq]

What did u do about it? Have you done bloodwork?

[@Moral-Medicin]

It will kill you. Don’t take it.

[@legion-t5j]

Kevin mann DISAGREES with evidence

[@Aasmrrrelax1]

🙏

[@NateBro]

Yep! He’s not swayed by anecdotal evidence. Probably a good thing

[@verivillon]

What evidence? He got side effects that went away lol. This isn’t anything new. What’s crazy is deciding that the drug is bad for you because you got temporary side effects and enhanced benefits.

[@exactly1176]

I call BS here . The HairChemist basically recommend oral minoxidil but does fear mongering about dutasteride ? OM literally has a black warning box on it and might damage your heart even at " low dose " while dutasteride has the same side effects profile as finasteride as it's shown in literature. Adults don't depends on DHT to function properly, they depend on testosterone. Dutasteride basically increses testosterone (more than finasteride) which is a good thing. I'm on dutasteride (was on finasteride before that) and noticed no differences whatsoever in terms of side effects. If anything i feel even better on dut (probably the increased in testosterone compared to fin). I even did sperm analyst in a laboratory (plan to try to have kids) while on dut and my sperm test ended up with good results on all parameters (including sperm count). What i do is i eat as healthy as possible, do exercise, don't smoke, don't drink alcohol, don't take hot shower / bath (bad for sperm) and i take zinc supplements. That's it. My sperm quality was even worse before i started finasteride (i did a test before). Conclusion : 5ar inhibitors are not birth controle. Millions of men have kids while on these drugs. Just have a healthy lifestyle and you will be fine. I feel like the HairChemist has a bias issue about oral minoxidil and dutasteride while here i talk about facts . Not a fan. Also the HairChemist seems obsessed with hairtransplant to the point where he does more hairtransplants even with a juvenile hairline which is a bit ridiculous.

[@aphelios9157]

The only side effect I have from Dutasteride is less volume in ejaculation, does that mean also less sperm count? or maybe not

[@exactly1176]

​@aphelios9157 semen volume is not connected to sperm count, sperm health etc etc... In fact you can have a low semen volume but a perfectly healthy sperm (it's also my case). But i had low semen volume way before starting 5ar inhibitors. So I wouldn't worry too much 😉. Just make sure you have a healthy diet, do exercise and avoid " too hot " showers / bath. And you should be fine

[@Obez45]

Hey Exactly1176 how is the 2.5mg of DUT twice weekly going so far? Any improvements yet?

[@exactly1176]

​@Obez45 it's definitely improving so far . I see new small baby hair a bit everywhere (that I didn't have before) but it's still too early to give you a proper conclusion. I will update on haircafe in 6 months . But definitely, the growth is better since I added 2.5mg twice a week on top on 0.5mg everywhere :)

[@Aasmrrrelax1]

@@exactly1176been on fin 1 my for 1 month and 15 days and full density back 🗣️

[@skrajina8037]

0.12mg of dut once a week is more than enough

[@Qwxiq]

This dose is not available

[@skrajina8037]

@@Qwxiq u take 0.50 and cut it into 4 pieces bro

[@TheMatrixgod]

Ive been on fin every other day 1 mill pill,i slowed down shedding like a month later,now being 6 months ive noticed im back up,so not sure if this is the fin shedding period or the fin stopped working,anyone have knowledge of this?

[@StgoergegreatStGoerge]

Thank you for your time Sir

[@atharvashinde9578]

This guy behaving like he's androgen insentive

[@deanhorn2369]

I bet when his balding gets bad he gona use duta again.

[@JuanCarlosLTO]

Glad to see nothing but medical doctors in the comment section! Allow me to go get my popcorn please

[@TheHairChemist]

It was great joining you in Prague Matt 🙏 see our references in the description section.☝️

[@johnmorgan7989]

Finally someone who actually admits thar dht is NOT a junk hormone. It plays an important roll in many parts of the body and brain

[@itaintobeezy]

It plays an important role during puberty. Not after

[@GAPIntoTheGame]

Nothing really to suggest it is important post puberty

[@letsgethair]

It is not just about DHT guys. You are shutting down the work of the whole 5AR enzyme family in your body. DHT is only one thing they mediate. DHT is what we are taught to care about in the hair loss industry. The issue goes deeper though. Maybe in another vid

[@MrShowoff27]

It doesn't, but if I did it would be an important role, not roll.

[@itaintobeezy]

@@letsgethair Would love to see a video on this topic 👍

[@robjows]

Who tf is this guy?

[@BlueOceanSky]

DHT is not useless. It is important, but the body can compensate without it in most cases. Hence the ~15% side effect rate on finasteride. DHT is more androgenous than T. T levels can fluctuate and the presence of DHT helps compensate for spontaneous low T circulation. It’s like a reservoir pump of androgens. It also helps maintain normal T/E balance. Side effects with 5ar inhibitors happen when a lack of DHT allows excess aromatization to occur, leading to excessive estrogen levels. This in turn signals your body to reduce LH and FSH levels, which means lower testosterone levels in order for the body to achieve normal estrogen levels. So now you have lower testosterone and low DHT when on finasteride. That lack of androgenocity can lead to side effects.

[@bennybenny7382]

how does the body compensate? does testosterone increase or something?

[@BlueOceanSky]

@@bennybenny7382 the body’s hormonal hypothalamus - pituitary axis is trying to find hormonal balance. When it senses excess estrogen it reduces the amount of LH & FSH hormonal to the testis. LH signal the testis to produce testosterone. The majority of Estrogen comes from aromatase enzyme converting T to E. So if the body reduces T production, E levels will come back to normal. DHT allows the body to operate at higher androgen to estrogen ratios because DHT itself cannot aromatize to estrogen. For those that can “compensate” Finasteride isn’t causing their feedback loop to decrease testosterone. This is probably because the estrogen increase was very minimal, they don’t have a lot of aromatase enzyme to aromatize T to E. Aromatase enzyme is typically found in fat cells. Those with higher fat composition will suffer from higher estrogen increases when taking Finasteride. Propecia studies indicated that total T and E levels increased by around 5-10% on average. So a personal who’s has a normal E level of around 24 ng/dl, going up to 26 ng/dl is still within the normal healthy estrogen range for men, and the body wouldn’t need to reduce LH and total T levels. Additionally, their current T levels, even without DHT, provided a sufficient level of androgens to the tissues that need it. Those who are overweight or genetically contained more aromatase enzyme will see the imbalance occur that manifests through side effects.

[@Vakator-29]

Would high t activities not compensate for this? I know it sounds like defeating the purpose but what of you can find the perfect balance? so that you have enough dht to be "alright" but also not enough to cause hairloss or excessive hairloss.

[@Fahin475]

But fin has shown to increase free testosterone levels in men by up to 10% so how are u saying it makes your testosterone levels lower...

[@BlueOceanSky]

@@Fahin475 in most men it does. But for those that suffer side effects you’ll find that either their estrogen is too high or their testosterone is too low.

[@SteveJonesOwnsDSP]

a good sum-up video, no fluff, just important bits

[@Jaythesparrow]

Nope, definitely fluff

[@1in7.8b]

Bros hair style is horrible

[@shopcenter2ify]

Who ?

[@vinceslapchopper]

looks like a freaking squirrel haha. if I were him, I would be much more insecure about being gray in my early thirties than planning my completely unnecessary 10th hair transplant. his gray hairs are making him look much older than any temporal recession he tries to fix ever would