Energetics of Glycolysis and Kreb's Cycle

[@SkyAssassin9]

I was very lost and you explained all this so well. THANK YOU !!! :D

[@hussainbiology]

thanks for appreciation..Glad it helps....✌️

[@atiranjanameshram5611]

thank you so much sir God bless you

[@hussainbiology]

thanks for appreciation...

[@mahanandachavan7259]

Tqsm sir for dis amazing vedio except more vedios from u 👍👍 I'm ur new subscriber 😍😍😍

[@catyvi]

thank you so much Sir!! This video is very helpful! 💕

[@mehwishnawaz9369]

Very nice Thank you so much for clearing our concepts

[@hussainbiology]

Always here to help....and i am really grateful for ur support 😊😊

[@joyitabanik5036]

Who ever the people commented here that it's a wrong calculation.then I m sorry to say you guys need to work harder to get to know with new research stuffs.and must go through new research papers.you will get it in Google itself. And sir thank you for this nice explanation..

[@hussainbiology]

thanks for ur support...

[@pals2436]

Thank you so much. I was confused about it for long time 🙏

[@hussainbiology]

glad it helps... thanks for appreciation

[@harunozkaya4226]

Good explanation 👌 Ty 🙏

[@onrebooting2658]

Thanks brother jazakallah

[@Bdhianaonzbajaonzosks]

Learned wrong calculation 2 year back Now it's cleared from here 💜💜 Thankyou And yours videos are very very helpful and best thing is the time 💜💜♥️♥️

[@hussainbiology]

Glad to hear that...Thanks for appreciation

[@lubnaazad2502]

abcd

[@sumeranazneen390]

marvelous way explaining.❤️

[@hussainbiology]

thanks Sumera for appreciation.... glad to know that it helps

[@nishat2000]

Why 8 NADH and how??? It's 6 NADH ( 3×2)

[@learnwithzoologist2436]

Amazing explanation thanks a lot sir

[@hussainbiology]

thanks for appreciation..Glad to know that it helps ✌️

[@alenjohney3813]

Thank you very much sir 🙏🙏🙏🙏

[@hussainbiology]

thanks for appreciation..Glad to know that it helps

[@cheriedhar8010]

Thank u sir for representing in such easy n understandable way...👍👍

[@hussainbiology]

It's my pleasure,,,, and thanks for appreciation

[@eyram8396]

Thanks 👍

[@smitayadav546]

Thanks you sir 🙏🙏🙏🙏

[@ayushrawat9424]

Sir a question was asked in our exam What is the net gain of ATP when each molecule of glucose is converted to two molecules of pyruvic acid? Options were:8,4,6,2 Sir we will go with which option? Pls reply🙏🏻

[@hussainbiology]

2 Net Gain

[@zmkhan8610]

Which one would be better for energy production glycolysis or TCA???

[@yogeshrajoria5825]

Tomorrow is my biochemistry xam. Hope i'll do it better.

[@hussainbiology]

All the best buddy and surely you will do better.....

[@hrithikchatterjee1773]

Sir total atp produced both glycolysis and tca is 38 in our book?and net atp in glycolysis 8 and in tca ar 24?

[@hussainbiology]

this is for advanced studies.. U can stick to NCERT for exams

[@hrithikchatterjee1773]

@@hussainbiology sir i am in bpharm

[@sasrikarajan7804]

this was so helpful

[@rajdubey7751]

Nice explanation sir..but in many books total atp is also written as 38 or 36 how are they formed sir

[@nwanagauche5915]

Depending on the shuttle mechanism it used Malate aspartate shuttle = 38 ATP Glycerol-3 - phosphate dehydrogenase. = 36 ATP

[@harshcharytalks6470]

Even though if we go with this we will get only 37 ATP.....coz in oxidative decorboxilation 2NADH×2.5=5 Glycolysis and citric acid cycle we will get either 30 or 32 Total....30+5=35 32+5=37

[@idowulawal8522]

Sir, I thought 6NADH are gotten in TAC, how is it 8, please?🙏

[@sasssovaa]

Sir then wat z the total atp produced in aerobic respiration?

[@hussainbiology]

30 to 32 Why this ambiguity is bcz the NADH produced in Glycolysis are present in Cytoplasm, so in order to deliver them into ETC we need to put them into Matrix of Mitochondria so for that we have shuttles. Malate and Glycerol Shuttle. ✓NADH sent to Mitochondria via Malate yields = 2.5 ATPs or 3 ATPs ( 3 Atps for lower classes ) ✓ NADH sent to Mitochondria via Glycerol Shuttle yields : 1.5 ATPs ( or 2 ATPs for lower classes) That is why we get difference of two ATPs.

[@hussainbiology]

updated *

[@sasssovaa]

Thank u sir 😇

[@coolstuff8868]

Thank you so much ☺

[@hussainbiology]

thanks for appreciation

[@hanaaaa8383]

thank you! helped me alot!

[@hussainbiology]

You are welcome ✌️

[@santoshmahadik9984]

Plz make video on How To Find ATP ?

[@Saud4793]

Sir ,are teaching at Resonance still?

[@dailyupdates2239]

What is the difference between net gain of ATP molecules in aerobic respiration and total production of ATP molecules in aerobic respiration?? What is the value of both qs?

[@vasudev1431]

Net gain implies that ATP produced was not used in the cycle so we can say, (Net gain=Total ATP produced-Used ATP) !

[@mohdshahwaj5454]

Thank you sir g... ❤

[@hussainbiology]

thanks for appreciation.. Glad to know that it helps ✌️

[@kusumbanaly3966]

Thnx sir🇨🇮☺️

[@hussainbiology]

You are welcome

[@harshitaggarwal3094]

If glycolysis is itself an energy producing pathway , from where does initial investment of "2 ATP" comes from , so to complete energy requiring phase.

[@wahajuddin2323]

God made it for a reason... Don't go crazy wit such type of Questions.. make your life easy and not complex thank you

[@edthoreum7625]

HarShit,not complex!

[@khyberempire870]

NADH provide that energy

[@Megha486]

Used from the cycle itself to activate Glucose

[@kasimmulani4663]

Thanks you sir

[@bidhisingh9982]

Jeeo Raja.

[@hussainbiology]

Thanks Bidhi for your unending support

[@dikshasinghrajpoot1058]

Give citric acid reactions with cone. HNO3. Please sir tell me

[@mohammadbaqirkhan8576]

Nadh and nadh2 both produce same energy or not ??

[@hussainbiology]

Yes , to be precise. NADH yields 2.5 ATPs in ETC

[@mohammadbaqirkhan8576]

@@hussainbiology thank you sir for quick reply

[@avyaripad7321]

Can youe explain how glycolysis form 2 net ATP? Because we add 2 ATP in 1st step and 2 phosphate in 3rd step so how 2 net ATP are produced while we have the phosphates is it re-arranging or producing?

[@varunkumar-ee7jq]

Bro very simple the ATP u get towards the end of reactions are not 1 as given in ncert They r 2*1=2(because the BPGA and PEP are 3 carbon compounds and hence it utilises one ATP but we r accounting for 6 carbon glucose hence we have to multiply by 2) Therefore u have 2 steps producing 2ATPs which equals 4ATP synthesised and 2 is consumed in the start as u said Hence net gain=2ATP

[@satyajitpodder8505]

Tca cycle produces 6 Nadh and 2 Fadh2..how it can be 8 nadh?

[@hussainbiology]

Actually i have summarised all together ,,,, I have included the 2 NADH from Pyruvate oxidation ( Pyruvate to Acetyl COA ) that is why it is 8 NADH , if we exclude Pyruvate oxidation then it is 6 NADH.

[@modesty8021]

Isn't net result of glycolysis 8ATP? I'm in class 11

[@hussainbiology]

Net Result of Glycolysis is 2 ATPs + 2 NADH ✓ 1 NADH then later generates 2.5 ATP in ETC Means Glycolysis generates 2 ATPs + (2 NADH = 5 atps) so a total of 7 ATPs.. But if we assume 1 NADH generates 3 ATPs in ETC ( like we study in lower classes ) that takes a toll to 8 ATPs.

[@modesty8021]

@@hussainbiology sir, am I supposed to answer 2 Or 8 now?please help I'm really confused

[@hussainbiology]

@Modesty 2 ATPs..... 8 in a way only when we Send NADH to ETC ,,,

[@invinciblemani7603]

Still confused how many atp are formed by cellular respiration 🤔🤔🤔 in 11 ncert net gain of 38 ATP molecules are produced..given

[@hussainbiology]

Stick to NCERT if u are going for lower level exams or go according to this video if going for NET , GATE or any other higher level exams.

[@invinciblemani7603]

@@hussainbiology one nadh #3 ATP.....one fadh#2ATp

[@hussainbiology]

good for lower level only. Otherwise it is 2.5 for NADH and 1.5 for FADH2

[@Tube-uv9fp]

In the citric acid cycle there is only a production of 6 NADH not 8 sir

[@shaifalipatel379]

sir in glycolysis during substrate level phosphorylation total of 4 ATP are formed. Then sir you explained it as 2 ATP

[@hussainbiology]

i am talking about Net gain ATPs....

[@shaifalipatel379]

Ohhh I got it sir. Thank you so much sir

[@musaddiqueashfaqueshaikh4333]

How many ATP are genrate frome anareaobic repiration ??

[@ramchandrasuthar2848]

Very nice bhai ji

[@hussainbiology]

thanks Brother,,,,

[@L0n30pium]

Sir in my ncert it's written for 1 pyruvate Krebs cycle occurs once and 3 NADH are produced. So for 1 glucose it's 2 pyruvate therefore ig its 6NADH so how come it's written 8NADH? Please explain sir I'm very confused

[@patelrajen7354]

Thanks sir

[@biology_mcqs3037]

Laga reh bhai

[@hussainbiology]

Shukriya Bhai,,,,, Congo for your 1 K

[@abdullahsaif5314]

Sir 6 NADH produced not 8

[@fatemaafrojeshithi8471]

It's very helpful sir. Jazakallah khairon. But in my book it's pointed that the net amount of ATP is (36 or 38).I was really confused about the amount so that I searched for this video but now I am more confused😅which one is the right answer... .!!!!...????....

[@hussainbiology]

See Fatema... Why this ambiguity is bcz the NADH produced in Glycolysis are present in Cytoplasmic , so in order to deliver them into ETC we need to put them into Matrix of Mitochondria so for that we have shuttles. Malate and Glycerol Shuttle. ✓NADH sent to Mitochondria via Malate yields = 2.5 ATPs or 3 ATPs ( 3 Atps for lower classes ) ✓ NADH sent to Mitochondria via Glycerol Shuttle yields : 1.5 ATPs ( or 2 ATPs for lower classes) That is why we get difference of two ATPs.

[@hussainbiology]

If u are studying for lower classes like at Secondary level then stick to ur books. This one is for higher studies where even 0.5 ATPs matter. 1 NADH in ETC Yields 2.5 ATP,s not 3 .and FADH2 yields 1.5 ATPs not 2. But for lower studies we opt out the fractions and go for 3 and 2 ATps respectively.

[@fatemaafrojeshithi8471]

@@hussainbiology oh I see. Now it's quite clear.

[@mtdpkmtdpk9698]

@@hussainbiology but sir, in the video you said 32 ATP , but in some books the mention it as 36 or 38 ATP, which one is correct, 32 ATP OR 38 ATP?

[@karnativenkateswarreddy4633]

Bro it's wrong calculation that U didnt mention the about energetics of linked step of glycolysis and c3 cycle And as a result net gain will be 36 or 38

[@hussainbiology]

If u are studying for lower classes like at Secondary level then stick to ur NCERT books . This one is for higher studies where even 0.5 ATPs matter. 1 NADH in ETC Yields 2.5 ATP,s not 3 .and FADH2 yields 1.5 ATPs not 2. But for lower studies we opt out the fractions and go for 3 and 2 ATps respectively.

[@abhijitsingh07]

@@hussainbiology exactly said

[@marypa2780]

@@hussainbiology it's better to pin this reply😊

[@مهراوه-ق2ط]

هل يمكن حل هذا سؤال Explain the energy yield of CHO metabolism from one glucose molecule.

[@sanjibdasx25]

I have seminar after 30 min ...hope it goes well 😂

[@hussainbiology]

All the best Sam. My best wishes......

[@priyanshinamdevshorts]

sir kabhi hindi se bhi dal dijiye kriye samjhna me easy hota h😊

[@hussainbiology]

haan g zaroor

[@farzeenkhan9779]

How 8 nadh in citric acid

[@awaisdiyar5753]

How? CAC = 1GTP=1GPT 3NADH=7.5 ATP 1FADH= 1.5 ATP =10 ATP Multiple by 2 =20 ATP BE SURE

[@MinahilAsif-iu5xv]

❤❤

[@wahajuddin2323]

Really helpful again... but it would be better if yoy explain where and when the two different shuttles are used... don't matter... M gonna appear the fucking exam wit your teaching... rhank you

[@bushrajaved3846]

Sir total ATP produces in glycolysis are four amd net gain is two Some video mentioned that from total four two used in the start but how they r produced in last two steps and two atp are already used to start process My question from where these two atp come to start process And how met gain is two

[@hussainbiology]

See Bushra, the initial Atps come from the Atp /Adp cycle , that is always on within the cells...... And whatever calculation is given in this video is 100 % authentic for higher/advanced studies... ( For NCERT there are some fractions which they don't consider so results are different on Ncert Books )

[@nishat2000]

8 NADH why????

[@kingpew162]

Kashur Zindabad

[@hussainbiology]

zindabad

[@sabeenaakbar7235]

Isn't it 38 atps🥴

[@deepakbk8053]

you are wrong .please check your wrong which you did

[@praveenreyno]

Sir use FOR not PER and instead of F u r using P sir please pronounce correctly because I seen this video 4 times also I didn’t understand u r English

[@hussainbiology]

Apologies.. I am not a native English speaker .. I have English my 3rd language

[@PreetiVerma-ny8tg]

If u can't manage ur videos in english then speak in hindi. It will be more effective.

[@joyitabanik5036]

Bro you guys don't even know this simple explanation .go through new research papers.it's a correct calculation

[@wardaq7724]

His speech is intelligible. What are you even talking about?