factors affecting drug metabolism including stereochemical aspects | L-10 U-1 | medicinal chemistry

In this Video we Cover,
1. physicochemical properties in relation to biological action
By @Carewell pharma
factors affecting drug metabolism including stereochemical aspects
factors affecting drug metabolism medicinal chemistry
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Lecture 10, Unit 1 Medicinal Chemistry 1, B Pharmacy 4th Semester
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Definition :-
drug metabolism :-
It converts lipid soluble compounds to lipid insoluble so that they are not reabsorbed and easily excreted out from body through kidney.
Phase I reactions of drug metabolism involve oxidation, reduction, or hydrolysis of the parent drug, resulting in its conversion to a more polar molecule. Phase II reactions involve conjugation by coupling the drug or its metabolites to another molecule, such as glucuronidation, acylation, sulfate, or glicine.
Factor affecting drug metabolism :- Many factors affect the rate and pathway of metabolism of drugs, and the major influences can be sub-divided into internal (physiological and pathological) and external (exogenous) factors as indicated below: Internal: species, genetic (strain), sex, age, hormones, pregnancy, disease. External: diet, environment.
Enzyme induction :- increase the enzyme ability
enzyme inhibition :- decrease the enzyme ability
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[@siddhipathare]

Thank you so much sir😊❤

[@ankurchauhan6202]

Dhanyawad guru ji

[@manishlohia4554]

Me watching all unit 1 videos, 1 day before exam 😅😅. Finished all unit 1 videos in just 2 hours. . . . . Nice lecture videos 😍😍

[@user-uq3ir7pg7x]

Thanku sir

[@rahulkumarmaurya4488]

Thanks sir

[@abusaifkhan7235]

thanx sir

[@vimlayadav1673]

Thank you sir ❤

[@bhavnamali4126]

Nice 👌👍👍

[@Shubhhhhh]

Sir , why we use chemical inhibitors ?

[@ganeshgani2220]

oka sir

[@SatyaPrakash-qc7dn]

Nice video

[@vivekkumarclasses6346]

👍👍

[@AwaisBaloch-uo9yh]

Love from pakistan

[@kartikeymishra7309]

Sir...apne jo medicinal chemistry k notes site pe diye ...aap plz saare lectures ko ek hi pdf me kr dijiye...kyuki sir iski 1 unit complete ho chuki hai...plz sir

[@divyashreek.s1639]

Where we find the notes??

[@shubhankarpatra5899]

@@divyashreek.s1639 description

[@vaibhavIngawale]

5th sem ki sari video jaldi upload kijiye sir

[@aribakhan8833]

L-10 notes are not available

[@dancervijay7831]

Please sir 7sem ki lecture start karooo

[@afruzurrahman5031]

Sir 2nd semester ke subject lecture shuru kijiye please

[@ravikanaujiya6372]

Sir notes lecture 10 ka

[@user-eu7lg8bk2m]

Sir Pdf open nahi ho raha

[@priyankaprajapati467]

Please upload pharmacology lecture

[@ashwiniborkar1808]

Sir first semester ke lecture start kiji ye plz pharmaceutics nd pharmaceutical Analysis nd Inorganic chemistry

[@user-eu7lg8bk2m]

4th sem.. Ke

[@mrigankadx9155]

Sir please upload more videos

[@carewellpharma]

Aaj ya kal se, Unit 2 bhi kr dege Start

[@mrigankadx9155]

@@carewellpharma thank u sir

[@akshaydhiman2853]

jai hind