(Fig 5-C.09) MRI Findings of Autologous Chondrocyte Implantation

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📌 Cartilife®: Fourth-Generation ACI
✅ Costal Cartilage as a Source
The study by Siclari et al. (2012) investigates using costal cartilage for cartilage repair.
It details the method of harvesting costal cartilage, expanding the chondrocytes, and using them in a scaffold-free approach.
The research highlights the advantages of costal cartilage, including its abundant supply and robust chondrogenic potential.
Cartilife® is a fourth-generation ACI in which pellet-type chondrocyte tissue is implanted without a scaffold, reducing the rehabilitation period and minimizing side effects such as foreign body reactions.
Donor tissue is collected from the patient's rib cartilage, cultured for 6-7 weeks to generate pellets containing cartilage cells and extracellular substrates, and then transplanted to the defective area.
References
J Knee Surg. 2021 Jan;34(1):2-10
Radiology 2015; 277:23-43
Clin Imaging. 2019 Nov-Dec;58:129-139
Journal of Orthopaedic Research, 30(6), 876-882
Regen Ther. 2022 May 3;20:126-137
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