First drug to slow Alzheimer's hailed as momentous - BBC News

The first drug to slow the destruction of the brain in Alzheimer's has been called a momentous breakthrough.
The research ends decades of failure and shows a new era of drugs to treat Alzheimer's - the most common form of dementia - is possible.
The drug, lecanemab, has a small effect in the early stages of the disease.
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#Alzheimers #BBCNews

[@user-zy8cy6hn6o]

Alzheimer's has always been one of the most horrifying things, you lose who you you are but stay alive it's a slow and in my opinion quite tragic death. Glad to hear this may be a thing of the past one day.

[@ashleyfairway.540]

never going to happen

[@vice.nor.virtue]

Theres no need to add IMHO bro, it's a horrible way to go...literally the kind of thing you wouldn't imagine for your worst enemy.

[@Reactivate100]

@@Candlesinthewoods stop spreading misinformation. Alzheimer’s is caused by aluminium poisoning in the brain. Best eat you’re greens. Iodine removes fluoride, heavy metals and radiation out of you’re body.

[@tiffymclarkey7948]

Assisted sucide all The way

[@SuperMissblueeyes]

Having lost my Grandad (my Dad's Dad) to Alzheimer's I'd like to say a huge "Thank you" to all the researchers & participants of this trial. Without any of you, this wouldn't have been possible. It's likely that my Dad will also develop Alzheimer's (it seems to be genetic in the males in our family). It brings me comfort to know that my Dad is just young enough to possibly benefit from this if/when he starts to show signs. And I'm very grateful that many other families will be helped by this too.

[@Maryhadalam]

Oh some goods news. What a rarity. Let’s hope it continues.

[@theprinceofpie]

Alzheimer’s is the most costly disease in history. Even a small step towards a cure is huge for everyone affected.

[@BoydGilbreath]

Do you know how much the drug costs? It will deplete Medicare and Medicaid to nothing over two years time. It is in no way a cure. It remains to be seen if it does anything. How do you say it reduced progression when no one has any idea what the progression would have been over that same time period? Alzheimer's progression is different in every case. And please go back to what is Alzheimer's and how is it diagnosed. Slippery, very slippery. And these Amyloid plaques , well if they exist in any human brain, and no one has proven that yet, do they cause Alzheimer's or are they a result of Alzheimer's? Years ago, a simple finding that the brains of Alzheimer's patients had greater amounts of Aluminum in them, thus, Aluminum causes Alzheimer's. Every one threw out every piece of aluminum cookware or utensil, medicines with aluminum salts etc. Not long after they said, Oh, sorry, that's Alzheimer's causes the brain to retain more Aluminum, not Aluminum causes Alzheimer's.

[@theprinceofpie]

​@@BoydGilbreath That's why the lecanemab results are a big deal despite all the problems. It's the first drug targeting amyloid beta that shows positive results. It's another piece of evidence for the amyloid hypothesis.

[@holmhelena]

Such a cruel desease, both for patients and families.

[@hamfahimkabir]

That's so great! Alhamdulillah. I hope it becomes available for everyone, everywhere.

[@pierceaero3005]

Yes! I worked in Alzheimer research. It was frustrating. The lab had a possible remedy that might have stopped the disease outright, but funding was cut. Slowing Alzheimers down now means any possible full remedy might still happen for more of these people than less. Like this guy, one hopes.

[@Reactivate100]

Alzheimer’s is caused by aluminium poisoning in the brain. Best eat you’re greens ! Iodine removes fluoride, heavy metals and radiation out of you’re body.

[@beadmecreative9485]

Can you pls share what your labs solution was? Because that seems impossible

[@ricp3352]

Can you please send me necessary information about this? If this lab was truly close, I am interested in getting funding restored to the project. Thank you

[@pierceaero3005]

@@beadmecreative9485 Impossible was what they told us when they cut the funding. The same science has since been used to give sight to some blind and color vision for a few of those genetically based patient causes. S³ or S-Cubed Research Lab, Sorrento Valley Rd. San Diego. Department of Defense Lab. Scientists from The Salk Institute were also at the BBQs. The science has been there to progress. Thwarting begins by calling it impossible. It is already being done before patient's genetically altered eyes. Guess how.

[@nguoithichhoasim1233]

The medical companies like to research and Or produce the medicines that can bring big interest like drugs for heart diseases , diabetes , cancers .

[@CharlesTheClumsy]

What is Vsauce doing in the thumbnail?

[@jc1006]

Why is the BBC pushing the shit mechanism of action for this drug which has failed in numerous other related drug trials and is associated with doctored images in preclinical research?

[@mccobsta]

The people who made this are amazing you guys rock

[@damithlakmal6352]

This would be great news for people who are suffering from Alzheimer's.

[@honoraryamerica5943]

Would have been nice to receive some basic information on how it works.

[@Pou1gie1]

This could help Chris Hemsworth, since he is at the early stages of his genetic diagnosis.

[@beadmecreative9485]

Wow a momentous event that’s a good thing! #wearelivingintoomanydisasters

[@jamesmit100]

Bravo!

[@public.public]

Farmers obtain twice the incidence of ALL serious diseases compared to the rest of the people. Which of the pesticides is causing dementia and how much less serious disease would there be in the general public if pesticides were banned?

[@kiabtoomlauj6249]

Can't ban pesticides, mid way through our arms race against crop pests... but I do agree with you that farmers have more major health problems than the average person, due to their being the most heavily exposed to heavy industry's most potent animal and crop chemicals. Back to the first issue (and these two are two parallel problems): doing giant mono crops that help feed the entire world of 8B+ people is different from growing a few rows and columns of garden growing in the backyard. Pests are powerful and in large armies. Crops can be destroy, if you don't have powerful chemicals to help control them. That is NATURE. Yes, we modify nature a bit... or, more accurately, we make it mutate at a faster rate, through the use of strong molecular compounds; but again, you just can't stop an arms race that both sides (humans and pests) have been fighting for many generations now. No matter what we do, when we create so much FREE FOODS, there will be uninvited guests. But we don't have to worry about "using ever more deadly compounds," since we, HUMANS, wouldn't be able to outlast pests... so we push this arms race as far and fast as we could. And if we don't use chemicals strong enough to kill both us and pests, in wholesale scales... their mutation to become "super bugs" may not be realized, either... so there will always be an equilibrium, such as what we have no... even if, again, FARMERS, as the first line of thing that keeps the species alive, WILL have to suffer more than other members of society....

[@public.public]

@@kiabtoomlauj6249 Grow up. The alternatives exist and there is no excuse for poisoning the world.

[@imthewatchman]

@@kiabtoomlauj6249 What if the pesticides are causing the need for more pesticides, when do you stop then? This is not Nature, these are dangerous chemicals that are spreading in the air, the water and in our food. i understand spraying some chemicals on crops that are infected, but that isnt what's happening. Not even in ecological farms. Farmers spray this canser on perfectly healthy food just in case. seems to me that farmers have forgotten how to farm.

[@user-hg9op1zf4r]

This news is encouraging to me, not only on a personal level, having seen loved ones deteriorate with dementia but also from a clinical side as I am a 2nd year medical student. Although the drug is in its early days the evidence of it slowing down the initial stages of Alzheimer’s is promising. It was also heartening to hear side effects were small. This truly could be the miracle drug they are hoping it could be. For those affected by this disease this new drug could offer more time to spend with family, and with a sound mind. David’s story was inspiring, and I hope the drug can give him more life. It also gives me hope that in the future we can eradicate this awful disease. I agree with David’s words “that it’s a horrible nasty thing and if we can slow it down.” I can attest to this having seen loved ones suffer. As a future doctor, wishing to do the best I can for my patients in the spirit of beneficence, these advancements give me hope.

[@chitterville7599]

This is exciting news .

[@TonysTechAndCars]

This is amazing steps!

[@TomNook.]

The US pharma company will patent it and sell it for 1000s a month. Only the 0.1% will be able to afford it.

[@taravaotahiti]

So true. That's the sad reality of it in this country.

[@GreenAppelPie]

Meh. It’ll undoubtedly be ridiculously overpriced

[@dougjones4987]

My uncle is taking this medication now and says it works so well he almost forgot he had the disease

[@Mcthindi]

That's great news, Now please do check side effects of it, if it has any !

[@broodyhenloloa]

Technology baby! Science !

[@vierwhey]

I wonder if magic mushrooms can help with Alzheimer since there are some signs that magic mushrooms help with creating new neural pathways in terms of the depression trails

[@skillmeup53]

Give it a go. Let us know how you got on.

[@FMFvideos]

magic? there is no such thing

[@imthewatchman]

@@FMFvideos Psilocybin might be magic.

[@mr.crowgamer6250]

@@FMFvideos maybe there was but it was lost to our people much like magic in lord of the rings after all the events took place

[@FMFvideos]

@@mr.crowgamer6250 no

[@user-hu1vi8oe2h]

Meditation can help too , if anyone keep practicing. Don't believe me ,but u can try with yourself

[@rudylampas2279]

Thanks LORD finally we have hope.

[@TheMariaKatre]

I also heard it can cause bleeding on the brain…

[@samsonsoturian6013]

The FDA will likely find the results not statistically significant

[@user-hu1vi8oe2h]

Good news for the patients,

[@adolfhitlerowicztrocki495]

Is that new Pfizer Alzheimer mRNA jab?

[@Heslehoff]

Yo, BBC, I"m really happy for you, I'mma let you finish, but THC and CBD had the single greatest attribution to the decline of Alzheimer's and dementia of all time.

[@ryanhunter5594]

Is this true?

[@dammitdan106]

@@ryanhunter5594 Leroy Jenkums ain't down with science and sheeit.

[@deborahwyndham-lewis5188]

It helps with cancer too, but you’ll never hear about on mainstream

[@EJ-el8gf]

Yes it’s true but they can’t make enough money off of it

[@Kuro-UWU]

That's not true lmao, you are stoned

[@polishdrow8409]

Big W

[@wynbrown7321]

Amazing how this hasn't been discovered before now.

[@sisfantasto7004]

Brain swelling as side effect is not the yellow of the egg. try to get rid of that side effect.

[@alexlex5792]

Amazing!!

[@jackdobson1992]

My nan doesnt even know who my mum is at times. My mums the eldest of six. I hope this drug helps.

[@ashleyfairway.540]

no it wont. Once the disease is in your brain there is no cure. and there will never be a drug that repairs the brain.

[@jackdobson1992]

@@ashleyfairway.540 my grandad died two days ago. I told mum that nan will be gone within a year. They were together 67 years.

[@ashleyfairway.540]

@@jackdobson1992 my mum has dementia and is in a carehome. it's not what she would have wanted. she doesn't recognise me. I wish the media would actually show what people become with dementia.

[@dammitdan106]

It's not just this drug, but a demonstration that monoclonal antibody theory can significantly slow early accumulation of Aß soluble and neuronal death in humans afflicted with Alzheimers. Many medications have been tried to squelch the accumulation of beta-amyloid in the brain and have failed to show significant improvement. We hope this line of therapy can improve the lives of your family members if they contract the disease.

[@chocolat-kun8689]

yeah, so whats the amount of treatments?

[@chamamemestre]

After the alpha Beta 56 debacle, I will hold my breath.

[@absmith6237]

Is this the drug that causes it or cures it ?

[@relativegifrelativegif8369]

I’ll be taking this in about 50 years

[@joaquin17171717]

£10,000 a shot.

[@curiositycloset2359]

Yay, now we can work forever.

[@thomism1016]

This is momentous🥳🎊🥂. Thank you to all, including David who participated💐🇬🇧⭐️. He may have been in the control group that received a placebo

[@skylark386]

Brain swelling is a serious side effect!

[@sajidkhanmahmood]

this is the concern about new drugs they may well be very effective but how many side effects are there.

[@venlafaxinedomperidone8377]

Why is everything made in the USA? Maybe socialised medicine is not that great i guess

[@sc1338]

Duh lol

[@venlafaxinedomperidone8377]

@@sc1338 everyone seems to be harping about how US healthcare is bad when it innovates the most drugs

[@sc1338]

@@venlafaxinedomperidone8377 no it’s not bad… it’s actually the most advanced. However it’s expensive.

[@venlafaxinedomperidone8377]

@@sc1338 true. Brits and europeans come to deal with the truth

[@kooshikoo6442]

You need to separate medical research from healthcare. In Scandinavia we have socialized healthcare, but not socialized medical research, more than in any other country,apart from University research, which is backed by government funding, as it is in mist countries, to varying degrees, including the U.S The U.S does have more venture capital though, which is a factor. Also, Europe is actually doing pretty well in terms of the pharmaceutical industry.

[@nawwk79]

Thor is ordering a truck load of these new drug.

[@XA1985]

This is going to make billions of dollars

[@kosztaz87]

Strange to look at it this way. How about rather saying it could potentially help millions of people?

[@XA1985]

@@kosztaz87 cuz money comes first 🙄

[@kosztaz87]

@@XA1985 For you or for companies?

[@imthewatchman]

@@kosztaz87 Does it matter? this guy thinks like the rest of the pharmaceutical industry. If it wasn't for the money this drug wouldn't be made. If it wasn't about the money they would look for a preemptive drug in most cases. especially alzheimers.

[@Azrael__]

Yeah, don't believe any of this yet, not after the last times they lied about this and other conditions.

[@RumpleStiltSkin69]

Just juice organic fruit and vegetables and lose the junk/fast food

[@mrrmn19]

At first I thought it's a new Vsauce video

[@mr.crowgamer6250]

Is it weed ? Has to be ganja

[@coolcat6103]

Funny how we have treatments but no cures£££££££ gravy train

[@maximusasauluk7359]

In order to cure something, we need to understand everything about how it works. We barely know anything about our brain, much less diseases that affect it.

[@KissMyFatAxe]

I think you underestimate how difficult it is to find cures certain illnesses.

[@auro1986]

does bbc accelerate it?

[@hbv9057]

How much please ?

[@JoeyBlogs007]

Yeah Yeah. It's called the aging process. Drugs are not the cure.

[@WpGaming1]

Not everyone suffers this lmfao. My Great Grandmother is 94, still drives a car, gets her own groceries, fully aware has no issues doing things for herself or remembering things.

[@imthewatchman]

my mother got it at 49.

[@jeanraphael6756]

If and only if it turn out to be true..as so many false promises along the way...then for all those suffering from that dreadful disease..Good

[@Candlesinthewoods]

Stop eating meat and dairy. Causes disease. As per doctors.

[@akeleven]

I'm not going to watch this video because I know the drug is going to be too expensive for ordinary people. So just stop giving us false hope.

[@helenpauls1496]

Depends where you live. America of course will be expensive.

[@elizabethorok9874]

Thanks a lot Dr Obulor for healing my Aizheimer diseases completely, i will keep letting the world know about your good works and your youtube channel sir🙏.

[@donnacabot3550]

Not without its side effects tho.

[@KissMyFatAxe]

Well duh.

[@ronlacker326]

Poor man. Doesn't know his own people are becoming a minority in their own land. Lost in his own mind. Rest in peace.

[@ricwhite612]

some good news, whatever you do dont give it to apes tho

[@razer0072073]

Why does God do this?

[@jdmmg4904]

♥️

[@chasefancy3092]

LoL this is an absolute joke! When you reverse age the cells in the body , the amyloid plaque will be non existent. It is tantamount to using the system restore feature in Windows. We are living in a simulated world where fiction is actually reality.

[@davidjacobs828]

There was another drug a while back which slowed alzheimers disease...it was called....Err...h..mmm...Err...Err...anyone fancy fish an chips ?

[@MetalheadAndNerd]

Lots of them. None reached the market.

[@alexkumm4488]

Im guessing we're going to give God the credit and not the scientists😂

[@public.public]

PREVENTION

[@HungaryEye]

CBD 👍

[@Reactivate100]

Iodine 👍

[@truthxposed8975]

The drug’s price will be an annual $26,500 for someone who is of average weight and Medicare won't cover it. To get an Alzheimer's diagnosis, you have to have Ambeta and Tau present in the brain. Problem with this is that 57% of these Alzheimer's cases have TDP-43 prion present as well. You cant cure, slow down, treat or stop a prion disease, it's a death sentence. Another 13% of Alzheimer's cases are actually misdiagnosed cases of SCJD. SCJD is the worst of the prion diseases. So, the price tag for this false hope is 26k? GTFO! With that bullshit. Keep reading, I'm not done. This was written in 2003'. There's over 6 million cases now. "Now people are beginning to realize that because something looks like sporadic CJD they can't necessarily conclude that it's not linked to (mad cow disease)," said Laura Manuelidis, section chief of surgery in the neuropathology department at Yale University, who conducted a 1989 study that found 13 percent of Alzheimer's patients actually had CJD. Several studies, including the one by Manuelidis, have found autopsies reveal 3-percent-to-13-percent of patients diagnosed with Alzheimer's or dementia actually suffered from CJD. Those numbers might sound low, but there are 4-million Alzheimer's cases and hundreds of thousands of dementia cases in the United States. A small percentage of those cases could add up to 120,000 or more CJD victims going undetected and not included in official statistics."-

[@maykolee]

Does it cure wokeness and feminism?

[@ryanhunter5594]

The cure for that is marriage and home ownership

[@porkeywings]

Planet of the Apes incoming

[@Floppa221]

That was a mutated virus in planet of the apes, this is a drug

[@dammitdan106]

Nukes, underground brain mutants and violent gorillas! Happy New Year of The Monkey.

[@Jesusmyfoundation-fi4rz]

DO GET READY, GET READY, GET READY GOD IS EVEN AT THE DOOR SEEK GOD WHILE NEAR FOR SALVATION . 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[@boiling_snow_water_]

sounds like more woke science.

[@KissMyFatAxe]

What on earth is woke about this? It's a medical advancement. Next you'll be tell me that a cure for cancer is woke too

[@boiling_snow_water_]

@@KissMyFatAxe it is. the only cure is god.

[@steaver3423]

where is news about conflict russia and ukraine?

[@Villaineditings]

It needs to be given straight to sleepy joe biden

[@DjMellowMoods]

Some ones got a fat bank account now

[@ilirshala2906]

@chrisshemsworth

[@elizabethorok9874]

Thanks a lot Dr Obulor for healing my Aizheimer diseases completely, i will keep letting the world know about your good works and your youtube channel sir🙏.