Gary Karpen - New Insights into Formation, Organization and Function of Heterochromatin Condensates

(Raw Video/Audio Only Due To Technical Difficulties) Gary Karpen received his PhD from the University of Washington’s Department of Genetics in 1987. He then performed postdoctoral work with Allan Spradling at the Carnegie Institute. Karpen was a professor at the Salk Institute for Biological Studies (La Jolla, California) from 1991 to 2003 before moving to Lawrence Berkeley National Laboratory (LBNL) and the University of California, Berkeley. Karpen is a Pew Scholar in the Biomedical Sciences, an author of more than 90 papers, book chapters, and review articles, and holds five patents. He served as LBNL Life Sciences Division Director from 2011 to 2015. The Karpen lab’s current research in the molecular and cell biology department at UC Berkeley continues a long-standing interest in chromosome structure and function, with a special emphasis on how biophysical and epigenetic mechanisms impact chromosome inheritance, nuclear architecture, genome stability, and human health.
This talk was given at the 2023 Symposium on Physical Genomics at Northwestern University, sponsored by the Center for Physical Genomics and Engineering and the Robert H. Lurie Comprehensive Cancer Center.