Heart muscle AP, ECC and Tension

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This video tutorial reviews the relationship between AP, ECC and Muscle tension:
0:00. Introduction
0:33. Anatomy of the graph
1:59. 1. AP propagates along membrane, down T-Tubule and activates L-type Calcium channel
2:14. 2. Ca flows into cell and binds to and activates the RyR receptor
2:25. 3. SR releases loads of Ca into the cytoplasm
2:31. 4. Rise in cytoplasmic Ca activates the myosin and actin to contract
2:42. Cytoplasmic Ca must decline for cell to relax (SERCA)
2:52. This is a very sequential process ...
3:43. In-A-Nutshell and Acknowledgements

[@danielxavier8984]

You are genuinely the best thing the universe has made. Thank you so much for everything.

[@TheNotedAnatomist]

Haha … You are so welcome

[@Dr_Slaykone]

Amazing video. Happy I found this channel.

[@ns687]

Thank you for this clear and coherent video. Your dynamic 'bam' and 'peeow' teaching style made it much easier to follow and visualise the ion fluxes. This sequence will definitely stick with me-though I'll have to resist using the sound effects in my exam answers!

[@TheNotedAnatomist]

Haha thanks 🙏🏻

[@Gudi923]

You're the GOAT

[@James-Specter]

Eid Mubarak Dr.David 🎉

[@lindathompson4770]

As a patient trying to understand a LBBB, could an imbalance of electrolytes cause the block?

[@alanwaterman1328]

Title: AP coupling to Systole