Hormone Therapy for Menopause: A Guide to Doses, Levels, and Delivery Methods | Dr. Susan

[@debbielucas9120]

Dr. Susan, you make everything so easy to understand. YOUR AWESOME!!!

[@peacepocket]

I think the main issue that people have with the pellets is, if there is an issue with the dose, you're literally stuck with it for 3 months before you can make any changes.

[@MaryBethMcCoy]

Agree. That’s why I won’t use pellets.

[@TheBody.TransformationCoach]

And it's not consistent as to when it wears off and how fast it wears off. I feel much better on daily T cream.

[@sheilamccurley7084]

That would be a wrong assumption. Your Doctor will prescribe a medication to lower your estrogen if it is too high. This happened to me once. During my one month post check-up my estrogen levels were way to high.

[@sunnievictoria9917]

@@sheilamccurley7084 yeah but testosterone is another animal. If it's too high, you can't lower it. If it's too high, it can cause irreversible virilization in women.

[@sheilamccurley7084]

@@sunnievictoria9917 It would take the same amount as men and if you have a good doctor who knows his stuff, then that will never happen. I 300 to stay just above the 200 estrogen. You are checked a month later to see if you need a booster of either and then checked again 3 months later to determine your next full dose.

[@u.s.a.-arg.2001]

I have been using bioidentical progesterone cream for 3 years and one of the biggest improvements has been sleeping. I put it on 20 min before falling asleep because it helps tremendously and I live that I can spread it out in 2-4 times a day that way I can keep it more stable during the last 10 days of my cycle. The info you presented is very valuable and appreciated but I do need to correct you about progesterone cream not helping you fall annd stay asleep because it does.

[@marsol_maris]

Dr. Susan thank you so much for putting information out. I came across your channel about a year ago, I educated myself in this subject and then I searched for a gyn specialist in menoupause, she is wonderful. And I've been using pellets since September and the benefits from it blew my mind away. My mind and my body feels like in my 30s....actually I feel MUCH MUCH BETTER than when I was in my 30s. Thanks again for showing us the way❤

[@photosbycarmenkc3509]

Wow, I been going through the M, thank u for ur information.

[@susanvanputten492]

Pellets were also a bad experience for me. I had testosterone inserted when I started menopause and I got a huge lump in my breast b/c my estrogen skyrocketed! It was stage 1 and I decided for mastectomy since I had already lost one breast via stage 0 cancer so now I am on estrogen patch and I have been for 5 years and it’s been great! Of course all doctors think I should not be on hormones but I don’t care I have a gene for heart attack and I feel amazing! Plus on testosterone via cream and oral progesterone:)

[@memcco]

i too had a terrible experience. thank you for sharing yours. Sore right buttock, prolonged, from insertion. And then right sided pain ensued.

[@zolozek3327]

Where can I get testosterone cream ? I HAD a really bad experience with the pellets they gave me a high dose that sent me into another dimension it's was horrible I'm on estraidol patch 0.25 lowest dose

[@drsusan]

That is not correct information. There are very good studies showing that non-oral estradiol does not increase the risk of blood clotting events so a patch or a cream or anything not in pill form would not increase your risk of a stroke. Numerous studies support that statement

[@sun-shine9305]

Possibly your mis understanding her. Because from what I understand from her is that the non oral versions she is all for.

[@NataliyaCoulter]

Seems liver doesn't mind taking progesterone every night, but not a good option for your liver taking estrogen orally.... That doesn't make any sense! If it's a pill its a pill, no matter of what it labeled. Progesterone IUD is a much better option.

[@mgines65]

Thank you for the valuable information. You have no idea how your video helped me understand so much about hormone therapy, there is so much negative information that keeps us from getting the right help. Thank you so much!!

[@svetlanatolonen7831]

Thank you Susan ❤️Greatings from Finland

[@Mira-t4n]

Australian here, I am big advocate of bio identical HT and I do agree that everyone has different absorption and different dosage requirements specific to your body. The best would be to test yourself when you are feeling great and still ovulating and once menopausal then you will know your limit and dosage you need to be on feeling great. otherwise it is a lot of ups and downs till you start feeling balanced. In Au the Dr test your hormones first besides your symptoms then the dosage ( normally they all start with low E 0.5mg which is hardly enough specially if you are still young in your 30ties or 40ties and your body is hungry for higher dosage!) so it takes for ever to level up and balance it with progesterone (the good ratio is somewhere 1:10 ) (so if your E is around 100 your P should be around 10). Also with the progesterone ,bio identical Prometrium capsules are better to take vaginal administration for better absorption and it also helps to reduce systemic side effects such as drowsiness and dizziness by passing the liver! Also when you are taking the Testosterone make sure you have good E levels of Estrogen not too high because T is converted to E via the aromatase enzyme ) so taking lower dosage is safer. Then just monitor your symptoms like: breast fullness or headaches are usually indicator of too high Estrogen or high anxiety levels and not able to get to sleep is low progesterone levels , waking up at night time and hard to go to sleep is low Estrogen, no libido and no energy is low Testosterone, getting hair on bizarre spots like your chin is too high aromatase levels = PCOS...I hope this helps ❣

[@elaynepringle5963]

Very helpful comment

[@maysmith7994]

How about hairloss with HRT?

[@havenwyld]

Wow, this is SO helpful!! Thank you so much for taking the time to share ❤️

[@Mira-t4n]

@@maysmith7994 it is most likely the low E levels or high T. Its good to have blood check done.

[@maysmith7994]

@Mira-t4n thank you. E amd T both are very low, even though I am on HRT. Drs don't really care. I increase the amount of the E gel to double but still losing hair. I am not sure if BHRT work better.

[@chaozee74]

To keep mentioning pellets in such a positive way and not talking about the risks or factors that women should weigh in on, as a Dr, I find that really surprising. 1. Pellets are not FDA approved, which means your insurance will not cover the cost 2. It can be difficult to find compounding pharmacies. 3. The higher cost 4. Finding a Dr that will be willing to prescribe and insert them, and Drs who do insert them, make a lot of money off of recommending this method to women. 5. There isn’t a guarantee that the dose they tell you is really the dose that you are getting, again, no regulations 6. It can be painful and uncomfortable for several weeks after insertion 7. You can’t take them out if you don’t like it or you have an adverse reaction to them, even at a low dose, women have bad reactions. 8. You are stuck with them for 3 months 9. Not all compounding pharmacies are the same and can use ingredients that are not safe or are contaminated by other ingredients they are compounding. 10. You will have the same high cost and possible pain and discomfort every 3 months Some women really do like this method and that is great, but if you’re not also talking about the downsides of pellets, you’re not giving women the full picture.

[@katherineantao4752]

100 % agree with you, thank you

[@cuellarfam85]

It is a high cost, you’re right there but it’s not painful at all. Myself, my husband and 4 of my girlfriends all get the pellets and haven’t experienced pain at all and the three years we’ve been doing it, nor did any of us experience any adverse reactions. Because they run labs six weeks after the pellets you do know how much you’re getting. It’s an option for sure. Expensive? Yes. But for some it’s worth it. I have rheumatoid arthritis, so I take many supplements and medications so for me the pellet is one and done at least for four months. Anything I don’t have to take daily I’m on board with.

[@jeannie4315]

@chaozee74; Thank you for sharing this to us women. I really do appreciate it. And yes the insurance do not coverage the pellets, because I did to pay out of pocket $625.00 and if i had known that FDA did not approved these pellets i would have them. Thank you again.

[@memcco]

we definitely need help from the bloodwork interpretation to the actual integration (dosage, how to apply) of these products. i'm getting exhausted by the industry before even finding the right balance of these hormones (estradiol, dhea, etc) Thank you for your work in this area!

[@LinziClairewheeler]

I know what you are saying but as women with hormaones pre menopause are hormones are unstable in fact too unstable to check it It’s different say to day and hour to hour - It’s true You would see if you tried it Like me Checked my bloods but always changing so untill in menopause when it’s more stable with hrt It doesn’t really help as to what levels of hrt you need ! I went with trial and error Estogel 2,5 was to high had lower back ache swollen So went down to 1.5 ! Wish it was easier but it’s very complex

[@faithf5846]

I wish someone would invent a hormone meter similar to a glucometer. I’m fearful of pellets because once inserted it can’t be taken out until it runs out.

[@drsusan]

Really important to get the right dose ! And yes that would be an awesome invention !😊

[@imaniwilson1848]

Wouldn’t THAT be amazing?!

[@robinstewart6820]

I was overdosed (testosterone) with the first and only pellet I had inserted! I was miserable until it finally was all gone.

[@angelao1953]

Don't be afraid! Mine are a godsend!

[@sherylmorgan4802]

Everyone is different my daughter had the pellets and her hair started falling out

[@leanandmean55]

This spring, I started HRT by weekly injection for T and E and pills for P. Levels are getting to where you suggest. Any comments on injections? Just curious. So glad for Dr. Susan. I spent my 40s having no one listen to me or even suggest any help. Finally, I have someone that will listen and excited to help, but pellets aren't an option.

[@larayne]

The male 5gr t-gel can easily be drawn up in BD syringes (I use two 2ml syringes and then you dispense very accurately from those. I put the gel in a sterile contact lens container first and then draw the gel up with the syringes.

[@russvet]

Also you can you place the gel into 10 ml syringe. And then put on the dose you want every day.

[@ShazWag]

Finding the right personal balance is so important. I developed endometrial hyperplasia and a large uterine polyp after being on HRT for a few years (a transdermal body-identical estradiol gel on my arm and a progesterone capsule in the evening), which meant I needed a D&C procedure. It seemed just one pump of estradiol gel on my arm was too much and made my uterus lining grow too thick (good thing I asked for an ultrasound scan to check, as I was getting jabbing pains!). Now I'm on one pump of _Lenzetto_ spray on my forearm skin once a day and still on the 200mg of progesterone (Femenita) in the evening. So far my uterus lining is fine, just 2mm, but I'll ask my gynaecologist for another ultrasound in 9 months to check it's okay. I think women on HRT should get an ultrasound of the uterus at least once a year to check for hyperplasia, adjusting their HRT dose if necessary. As for blood tests for hormone levels, both my gynaecologist and family doctor said they're pointless, since it's not the same for everyone and hormones are constantly fluctuating, and I would imagine women would know from any symptoms they're having. Regarding testosterone pellets for postmenopausal women, some studies have raised concerns. E.g. pubmed.ncbi.nlm.nih.gov/33518182/

[@drsusan]

Agree it's very personal ! Dose is critical

[@Lbb789]

FDA will never approve pellets bc they're not a pharmaceutical product. Same with the NIH. They get their funding from Pharma. So guess what they're going to say....

[@jennieoh8543]

A Mirena coil really helps mitigate that problem and keeps your uterine lining thin. My Meno specialist does not prescribe testosterone and I am good with her decision for me personally.

[@ShazWag]

@@jennieoh8543 My daughter had the Mirena coil and could feel it when she sat down. Also, there are many cases of the coil embedding itself into the uterine wall and, even worse, migrating to other organs. When this happens, surgery is required and damage such as lesions can occur. It's actually not that uncommon. I'd prefer to stay away from it.

[@jennieoh8543]

@@ShazWag Oh my I have no problems thank goodness!!!!!! So sorry she had to go through that :*( I have had one for years.

[@vhelma21945]

I feel like a second class citizen .. when the FDA doesn’t approve & test HRT and have to fight this uphill battle without any tools 🤯!

[@carannrus]

Your description of this video says that it discusses level, which it did not! Why is it so hard to find a chart that shows optimum levels for post-menopausal women on BHRT?

[@sunnievictoria9917]

optimal test levels for women is 50-70. Optimal estrogen levels are 100-300

[@sunnievictoria9917]

its also about how you are feeling and symptoms, every woman is unique

[@celeste-236]

A level less than 60 means that you’re losing bone. So to stop or prevent bone loss, your estradiol blood work level should be at least 60. So, optimal post menopausal blood work levels are considered to be in the 60-80 range .

[@inspolouise4244]

Go Susan! Come over to Aussie you are most welcome. I have just started The AndroFeme so your feed back on that was awesome. Yes the Govt makes the GP test 3 weeks and then every 3 months to see whats happening with levels. The testing is all free covered by Medicare so we are lucky. I am struggling though how do you know when you have correct doses for all hormones is it a symptom thing or more of just feeling like you have your mojo back.

[@Outofmycastle]

Thank you for all the valuable information. I’m currently trying to decide on the best course of action regarding hormone replacement therapy during perimenopause. From what I’ve understood: 1. Estrogen Options: You recommend estrogen in the form of patches, cream, or pellets. However, you expressed concern about the variation in the levels of hormones like estrogen, progesterone, and testosterone in the blood. You mentioned that these fluctuations are normal, but at the same time, you seemed concerned about the effects of these variations. This is a bit confusing - should I be worried about these hormone fluctuations or not? 2. Measuring Hormone Levels: It seems that measuring hormone levels is quite complex. How is this done accurately? If hormone levels vary throughout the day, how do you ensure that the measurements taken represent an accurate picture over other days? It seems challenging to get a clear understanding of the hormone balance with these fluctuations. 3. Progesterone: I learned that progesterone is better taken orally as a pill because it isn’t well absorbed through the skin. Plus, taking it by mouth provides the added benefit of helping with sleep, which is especially valuable during perimenopause. 4. Testosterone: For testosterone, you recommended taking about one-tenth of the male dosage. However, you mentioned it’s difficult to divide those doses properly. Could you clarify more about this? 5. Timing: You didn’t mention what time of day is best for taking each hormone. I’d really appreciate it if you could provide advice on the best timings for taking estrogen, progesterone, and testosterone. I found this class very informative, and I’m still in the process of choosing what to do, but these are the key points I’m considering.

[@ImHandlingIt]

In early 2023, my estradiol was 5.8 and testosterone was 17.9. Doc started me on compounded estradiol and testosterone cream (4 clicks estradiol 2 mg/Test. 2 mg). And nightly progesterone 100 mg. After 8 months we tested and my Estradiol went up to 110 and Testosterone was at 21. Symptoms seemed to improve (better sleep, libido, no night sweats.) In the past month or so, I’ve noticed more anxiety, worsening sleep, and lowering libido. Tested again and my Estradiol is way down to 9.2. Testosterone is at 31.5. Doc believes in treating symptoms, not labs. But had we tested more regularly, I wonder if we would have seen my levels trending downward and could have adjusted before I started getting symptoms. I also wonder if starting me on Estogen and testosterone at the same time was a bad idea. Some camps say Trudy compete for absorption. Has anyone experienced this? Should I push for separating these hormones?

[@ImHandlingIt]

BTW, these labs were drawn within 3 hours of applying.

[@katc9405]

I agree to get our bloodwork to know where the hormone levels are at BUT the pellets are waaaay more expensive compared to the patches 😌

[@NOELGARAGESALE]

Why does prempo stop working after a period of time? I have been on prempro for almost a year now. Started on a low dose. It was the best 3 months of my life, and then it stopped working. So I went to the next level of dose. Same thing. Had 3 great months, and then it stopped working. Again, it happened on the highest dose of prempro. It seems that no matter how many times the doctor increases my rx for prempro, the cycle will repeat. Can you explain why this is happening? After watching your video, i now know there are other options out there that are better and safer. I scheduled an appointment with a menopause specialist who is more informed with the latest treatment. Can't wait. Thank you for giving me the tool.

[@aubreylowe1361]

Fingers crossed my doctor offers me any form of testosterone and checks my blood levels for estradiol patch! She didn’t want to do any of those things my last visit😳 🙏🏼 🤞🏻

[@Lbb789]

find another doctor.

[@angelao1953]

What @Lbb789 said! Life is too short to deal with indifferent, uncaring, unequiped doctors or providers! I have been on pellets for less than 2 weeks and my knees quit hurting, my ankle quit hurting, I have some libido again (!!!!!) and I feel SO much better. It was hard for me to find an MD/gynecologist who was also an HRT specialist and was super knowledgeable (and she also was forced into menopause early due to chemo herself) and fabulous! It was not easy finding her, but I did! Often providers don't advertise that they are HRT specialist because insurances poo-poo this (even though they should not). DEFINITELY find a better doctor. You are worth it!

[@aubreylowe1361]

Thank you and you’re entirely right! I was able to find a new doctor who I believe will be a lots more helpful and have an appointment in June. I will still see my other doctor on Friday since I already have the appointment but my expectations are low. I too have really bad joint pain lately even though I eat a very healthy diet and am very active. Do you think your pain has been helped by the testosterone? Have a wonderful day!🌻

[@cheylou1]

Same here you might live in canada

[@aubreylowe1361]

@@cheylou1no but right near the Canadian Border in Blaine, WA. 😊

[@MC-iw6nv]

I’m on BIO identical HRT. I’m not comfortable with synthetic HRT.

[@RBeck-uz6kg]

Yes I use T gel as well. Can get is prescribed and decant 1 packet into a clean container then apply amount recommended by health professional. When that amount runs out, decant another little packet into container. A bit of a pain, yet it works for me.

[@MarianneWilkinson0312]

I do the same thing. It’s ‘off label’ use as a female but I know it is less than a compounding pharmacy. I get the small packets and I to apply every 3-4 days a packet but I do the same thing and use a quarter of it every day for four days. Within a week the urgent dramatic I have to urinate feeling went away!

[@b.f.2581]

Dr. Susan, Thank you for the invaluable education. I will appreciate your perspective for my question. I have been on estradiol, Mylan patches, .05mg/twice/wk. I thought the patches are synthetic, made in the lab. I don’t know where it was sourced? Should I be concerned that it is not a plant based? I think the compounding ones are plant based. Is the plant based, bio-indentical products better than the synthetic, bio-indentical products? Thank you for your kind perspective and all you do❤️.

[@rmh691]

The problem with compounding pharmacies is that you are really trusting that the pharmacist and pharmacy is reputable and delivering the same dose with each prescription. This has been shown time and time again not to be the case. For example, and this goes for any drug - say your prescription is for 5 mg. dose. When they looked at prescriptions issued over a six month period, On a 30 day refill schedule, all six prescriptions had widely varying strengths from a quarter as much to three times as much. So until this is FDA approved and you can buy it that way like you can buy estrogen, it’s a crap shoot what you are getting month to month from a compounding pharmacy. Also, you do not mention that there are patients where the pellet dose is too much where they get side effects and you are stuck if that happens for as long as those pellets are in you because they cannot be removed. If you’re using a patch or a cream and the dose is too high for you, you simply stop using it and don’t take the next dose. That’s a huge difference and I don’t understand why you don’t mention that.

[@NiaLaLa_V]

Yeah I have a hard time trusting anyone now because I worked as a clipper in the legal cannabis industry in washington state. I am also a curious person so I got close with the managers and learned about the process, and I found out they were selling stuff under the same name so people think it is always the same product but it wasn't. It varied from plant to plant, harvest to harvest, the levels of all the phenols and flavonoids and stuff they market it for were changing in every single batch. The whole year I worked there they never figured out how to get consistency in the product but they kept selling it and they were meeting all legal requirements because they only make them monitor things like the thc amount.

[@jisbell6308]

Lots of information. Thank you. It would be very helpful to include what the desired levels are for estradiol and testosterone if it is so important to check levels.

[@MsFrancoise01]

I think for estradiol it should be around 400; 800 is high

[@jamiescho7420]

How do you feel about taking progesterone for 21 days and off for 7 days? Any advantage/disadvantages?

[@anne-louisegoldie]

I'm very nterested in this too.

[@ShazWag]

@@anne-louisegoldie My gynaeloclogst suggested I do this to try and encourage a bleed, as my endometrial lignin was becoming too thick from the estradiol, but I didn't bleed and eventually needed a D&C. I've since been on just one pump of _Lenzetto_ transdermal spray, instead of an estradiol gel, and I still take my progesterone every day - both continuously, without any breaks.

[@bbjonas4233]

​@@anne-louisegoldieWhat is the benefit to this?

[@angieflowe3925]

Would love to know this too

[@anne-louisegoldie]

@@bbjonas4233 I need to know more about it, but I've heard that a few days break from progesterone may be beneficial for the receptors. From another menopause specialist on KZbin 😊xx

[@lisaaudy352]

I work in a clinic where we provide timing sheets for blood draws. For example, we instruct our patients to take estradiol 6 hours prior to their lab appointment (if it’s oral).

[@drsusan]

It's great to have protocols, but I would definitely tell your providers not to take any estradiol orally that is not standard of care and increases the risk of blood clotting events!

[@silviadamen]

Women's International Pharmacy offers Testosterone in a cream and it's VERY easy to order and use, once you have a prescription from a doctor. The key is to FIND a doctor that will actually prescribe it!

[@celeste-236]

In the USA, for women, testosterone is considered a “controlled substance “ and must be created through a compound pharmacy ( expensive), unlike for men who can go to CVS or any other pharmacy and get a testosterone script filled easily and inexpensively. I learned that fact from Dr Shawn Tassone, a gynecologist who is licensed in 34 states and does virtual appointments and actually accepts new patients.

[@sheahill3340]

I have been on pellets for ten years, before and after hysterectomy. No problems and no adverse effects. I tried shots and patches and both were much more problematic.

[@denisepeter7050]

I love these sessions. So informative. ❤❤❤

[@LindaJones-z6o]

I am 66 and been on HRT for 15 years. When I first started I was taking .037 patch and 100 mg progesterone daily. After a few years I had numerous breast biopsies because of suspicious areas. I got tired of it and switched to taking progesterone the first 10 days of the month only. I was told progesterone keeps your breasts in an agitated state. I would like to go back to daily dosage but cautious. What do you recommend?

[@nikas8318]

Do you have in your practice postmenopausal patients on testosterone only without supplemental estrogen and progesterone? And if yes, do you see them converting testosterone into estrogen in blood work?

[@Juliet875]

So ridiculous they approve pellets for men and not for women. I'm on pellets for Estradiol and Testosterone, love them. So easy to deal with, don't even have to think about it. I was on Progesterone cream and creams just don't work very well. I'm taking 200mg pill now, game changer. Pellets are great, just have to find the right level. Yes, blood work is so important. Thank you so much, great video!

[@goodsingersnotjustcutesong1323]

No one seems to mention costs. Many, if not most, insurances won't pay for the testing or pellets and insertion visits.

[@NotACat2237]

This came at a good time. I'm currently switching off the patch because I started having an allergy to it.

[@ginas57]

Same here. Started on a patch but my skin gets red bumps every single time

[@Sumermak]

Don’t go off it… just switch the patch to a different ones your probably allergic to the adhesive.

[@sassyt1545]

The NIH did a study on contact dermatitis from estrogen patches and the conclusion suggested site rotation of the patch and/or a small amount of clobetasol (topical steroid), prior to patch application to ward off allergic skin reactions.

[@monicagalvan5645]

Can you provide healthy ranges of estradiol, testosterone and progesterone for post menopausal women on HRT?

[@drsusan]

There is no consensus on this and there is hot debate about it, but in general Estradiol levels in the 40 to 100 pg/ml range reduce symptoms and also provide protect protection for all of the health benefits that we want without any adverse side effects The highest levels of testosterone that we achieve as women in our 20's are approximately 50 to 100 ng/dL So my personal opinion is, we should stay somewhere within that range and at levels over 150 we start to see side effects

[@bluejean-1968]

I'm new to your channel. You look amazing!! As far as your teachings, Menopause Barbie could learn a thing or two from you. For years I used a 20% compounded progesterone cream only to find out that I should have been using a 3% or 5% cream for much better absorption.

[@nbinghi]

Thank you so much for all the helpful info! But, what is a compound pharmacy and how does one find one?

[@sunnievictoria9917]

google

[@kathealy60]

Great episode! I appreciate the dosing suggestion for the testosterone pellet; I believe I got too much when I got mine originally. What is your feeling on the dosage for estrogen calculation for the pellet? Thank you!

[@laila11778]

I think my dosage was too high too because the tri-est cream made my skin blotch terribly. I just quit. It was just too much but they said it was the lowest dosage.

[@drsusan]

6-10 mg for E in pellet - I start almost everyone on 6 mg unless they are over 200 pounds

[@kathealy60]

@@drsusan Thanks so much - this is helpful as I see my practitioner today!

[@kmjdebay]

@@drsusan Thank you. My OBGYN provider was trained by Rebecca Glaser and we worked on the right T dose for about a year and I was OK on 100, but then in 2021 I chose to increase to 112.5 to better protect my bones. I am on 112.5 T and 25 E. Next time I will try lower E, but I have had trouble thinking on a lower dose. Theoretically, is 6mg equivalent to .05 patch? I was on a patch for years at .1, then .075, until I stopped making any testosterone. I've been on pellets since 2010.

[@hulasenorita]

@@drsusanis 125 for testosterone dosage good for 132 lbs is my weight and 5.2 height.

[@tinajames2940]

First appt next week. In zoom pre-appt meeting she said she doesn’t check hormones because post menopausal there are none. She just puts patients on very low level. All women have some levels of hormones at different times in life right? Considering canceling and looking further for a doc. This one was in another state. Aren’t many close by for this type treatment.

[@staceys3019]

Could you please explain how the results vary from a saliva test compared to a blood test.

[@drsusan]

The idea is that saliva measures free levels of T - we can also check that in blood now. So usually more difficult and expensive to do salivary testing and no additional benefit

[@Jesusiswatchingyou-123]

What about sublingual or buccal method of estradiol tablets?

[@christyhelferich2325]

Thank you for all of the great information.❤

[@doodieevanshenagan3330]

With patches, if you swim, one should get water proof bandaides to cover the patch……wondering about baths.

[@encinosarah]

Where are your recommendations for proper/ideal estradiol serum levels?

[@Ann-MD]

Hello, thank you for this video. Have you seen anyone using the estradiol patch and experience bleeding?

[@jenniferwinograd]

I started my estradiol patch at .025 dose and my symptoms abated. The things I noticed the most were that hot flashes, heart palpitations, insomnia and lack of coordination went away. However, another OBGYN I follow on KZbin mentioned .025 is too low of a dose to have an impact on the main reason I am taking estradiol: long term bone, brain, and cardiovascular health. That made me try .05 dosage which made my breasts incredibly sore. It was intolerable. So I went back down to .025 dose which feels like it's the dose that eliminates my symptoms and yet I'm still wondering whether It is enough to protect my bones, brain, and heart. I'm hoping it will. Because of this video I just reached out to my doctor to ask if I can get a blood panel to check my hormone levels, but I'm wondering if it is possible for some people that .025 is in fact enough? I'm not on testosterone and I'm still confused as to why I would want to be on it other than libido? Beyond the libido aspect of it, is there any other reason to be on it?

[@msmc2685]

Health benefits are not dependent on your dose. It’s your blood levels. You want a mininum of 60 to protect bones for estradiol. I keep my levels at least 250. That’s where I feel best.

[@ShazWag]

You could have a consultation with _Menopause Taylor_ , who also has a You Tube channel. She really knows her stuff!

[@christinemack2153]

I believe it can help build muscle.

[@drsusan]

Blood levels would be helpful in your case. Happy to see you in person or virtually!

[@jenniferwinograd]

@@ShazWag Thank you. But a Menopause Taylor video was the reason I went up to .05 dose. She mentioned that the minimally effective dose for long term health benefits was a .05 patch. It really was too high for me though. I was very uncomfortable. I am 5'8" and weigh 123 pounds. I wonder what role BMI plays in dosage.

[@Susan-xg7qn]

I am missing something , not sure. You say to get blood work done to check your levels, for estrogen & progestrone, but then say how can they be accurate if you levels go up & down, depending on time of day you apply gel , or have a patch ? So, this is confusing and contradicting ? I am 61, 4 years on HRT, 1 pump Gel, and 100mg progestrone. FYI.

[@drsusan]

No, it's not contradictory. I explained it as well as possible. It's important to time the blood draw. I mentioned in detail if you're wearing a patch, it doesn't much matter when you draw it however, it will fluctuate during the week and we want to be not excessively high or low with progesterone and we don't need to draw the blood level and with cream or gel you want to draw it 6 hours later. As I mentioned the reason to do this is to make sure your level is not excessively high or zero which is possible, even with a patch. The alternative is not drawing your blood at all and you would have absolutely no idea what's going on so we need to understand that levels to fluctuate, but we want to rule out having excessively high or close to zero absorption.

[@DianneElizabeth64]

If we had testicles, you better believe all this would be solid science by now. I have to use the infrared sauna for mycotoxins. I have very sensitive receptors in my breasts & lymphnode. Going to try a cream next

[@marinawong9662]

Why don’t they have time release version of these hormone pills? Is it really difficult to get one done?

[@kellywebster6428]

Great idea to me

[@Publious]

When do you draw blood after pellet insertion Dr Susan? And what are optimal levels?

[@jartotable]

What about splitting up the cream dose into 2 doses. One on am second at 5pm?

[@cleanqueen75]

I’m 67 and have been on Prometrium 100mg for about 2 months. I also take estradiol/testosterone cream since 2012. I eat healthy, no dairy or gluten, take DIM and other supplements like Vitamin D3 etc. In the last 6 months I have keep putting on inches and weight. I have really been struggling with my weight. My hormone doctor sent me to a nutritionist for 4 months. Nothing has helped. I’m really considering going off HRT. I’m frustrated and nothing is working!

[@rupalpatel5749]

Very good information, thank you. Just started climara 0.025mg patch once a week and prometrium 100mg daily, 2 weeks now. Feeling bodyache, sinus congestion, sore throat and headache. It was also showing under adverse reactions in the package insert. Should I try it for few more weeks? Will it go away? Other options? Thanks

[@BarboraVystejnova]

Thank you for so much information ❤️

[@finnster5800]

I’m wondering if the same options and FDA approvals are in Canada?

[@emcoss]

I purchased T gel last week in Mexico. I’m using 1/20th the men’s dose to start. Let’s see how I feel.

[@peacepocket]

is it over the counter in Mexico or did you have to get a prescription?

[@emcoss]

Over the counter.

[@biquarius]

So how is it going with the gel?

[@emcoss]

It’s going great. Increased dosage slightly after 2-3 weeks. Starting to feel like when I had the T via pellets.

[@jenniferv]

Ridiculous you had to go to Mexico for it. This is crazy.

[@sueharrison8818]

I was given Estrogen, progesterone, testosterone, cream after ONLY A SALIVA TEST... JUST STARTED THE CREAMS, ON A WEEK AND ITS NOT TOO HIGH OF A DOSE, BUT I did not get blood test... Is SALIVA TEST GOOD ENOUGH? IM CONCERNED!!! THKS MUCH

[@marlenede-abel1336]

This was very interesting - I was wondering what your thoughts on trouches (not sure if we have the pellets in Australia).

[@jennysiepka9900]

They work well too. Just make sure the base isnt polyethylene glycol❤

[@jackiemansfield8325]

The gyno provider I just visited told me that I don’t need any blood work, or hormones. I’m 64, 16 years without periods, and want to start taking hormones to prevent any possible future diseases, but am adrift now…

[@annab5090]

See a different doctor. Find o e that works with hormones.

[@kimberlypotts8922]

Dr. Susan, I began my perimenopause journey with a dark green estradiol/ testosterone pill. Within months realized there was way too much testosterone here. Then moved to pellets. Wonderful… until it wasn’t. Engorged clitoris, growing hairs on my chin, raging anger… My blood felt like it was fizzing or vibrating. Totally a cowboy experiment, to use your own words. I ended up in the emergency room in tachycardia. Went back to estradiol 1 mg, then adjusted up to 2 mg. Felt great again, initially, after the upgrade to 2 mg but now on a rollercoaster again. I simply am at a loss. My bloodwork shows testosterone at 0. Absolutely no libido. At this point my only goal is to just have energy and be positive. I know that I can do better but just do not know where to adjust.

[@MarianneWilkinson0312]

Dear Kimberly- so sorry to hear all that you went through. Please think about a private consultation with a meno doctor such as: Dr Louise Newson, and Dr Mary Claire Haver (i think), Dr Barbi Taylor. You should be able to do them via phone or Zoom. Best of luck!! The first one I listed I have followed for 5 years now.

[@3hotspuds]

I've had something similar happen with the T and vibration sensation. Since the pellet is now gone and your level at zero maybe try the cream in a super low dose?

[@biquarius]

Do you have a naturopathic doc? They make testosterone creams that can compound exactly what you need 😊

[@susandeakin6513]

My GYN doctor would never agree to prescribe testosterone made for males. I had to cry in her office to let me have some compounded cream T for libido. She gave me 1% cream.

[@SusanWautelet-ob9xh]

Do you feel like the cream is working? i just had my bloodwork drawn for T. No libido for me, i'm foggy and very moody so i'm hoping the T will give me the last of the missing puzzle piece.

[@janereinhardt4715]

Maybe a 1% placebo.

[@drsusan]

1 percent is meaningless- you need to ask how many mg you are getting . 5 mg daily would be standard (at least in Australia !)

[@CatamaranChannel]

1% = 2.5mg is fine, just use more. 2% = 5mg is the standard, which is 10 times less then what men mostly get/want.

[@sandandsparrow]

Unfortunately health insurance doesn't cover compounded creams, pellets or sprays.

[@MsFrancoise01]

Is the Divigel bio identical ? If not, it's not the horse urine, right? Just making sure 🙏🏼💕

[@thearmchairparisian5343]

Here’s a question - reflux and HT. I was on oral compounded BHT for 5 years and suffered the entire time with daily reflux that interfered with my quality of life. But hey, I didn’t have debilitating hot flashes and was able to sleep most nights, so I put up with it. I went off the BHT because I had a funky mammogram - that in the end turned out to be nothing but my doctor told me I should get off them. Fast forward a year and 2 stable mammograms and the doc is denying that he told me to get off the hormones and that I can go back on them. I had another doc tell me the reflux was because it was oral BHT, but in reading, I am finding that all delivery systems are said to cause reflux. Anybody have experience with this? Any BHT that *doesnt* cause reflux??? *I should note that the year I have been off the BHT, the reflux is blessedly gone.

[@Abbasblesseddaughter]

I use lavender oil. It has really helped and no prescription.

[@bbenabe]

For what?

[@debbielucas9120]

Sleep?

[@natashyas4149]

Estrogen patch. Progesterone pill at night b/c helps you sleep. Testosterone pellet, compounding pharmacy.

[@katrinabennett2759]

Dear Dr. Susan, how do you feel about pulse-dose 1st 12 calendar days of month only for a post-menopausal woman? I am concerned that my better since Progesterone-sleep will be affected and this will also cause a "bleed" 😢

[@angelinadrobina5037]

A question for you if you would be so kind. I asked for progesterone to help me sleep and it did but I felt pretty rubbish the next day / I commented on one of Dominique’s videos and Dr Taylor said of course you felt terrible you don’t need it (because I have had a hysterectomy and still have my ovaries) so I am confused and still sleepless 👀👀 I do see a prominent OBGYN bashing ‘Pellet farms’ and I do think it’s unnecessary as you can clearly see you and others that promote them are so genuine and want to help women so don’t condone that attitude Thank you for all of your hard work 🙏🏻 I love my Estrodial gel and am waiting the three months to see a specialist to get testosterone in Australia / I’ll be sticking to the lowest dose after your comment thank you for that 🇦🇺

[@drsusan]

Barbie Taylor is correct that you don't need progesterone for uterine cancer prevention but it does help many women sleep but everybody is different so there are lots of other wonderful products I can help with sleep like magnesium 5HTP melatonin and gaba. I would make sure that you're taking bioidentical progesterone that does help most people sleep, but everybody is different and I've made a lot of videos about sleep. I hope you find them helpful.

[@tesiemarie8942]

I was told you still need progesterone. Our ovaries still make it and Estradiol. Why would you replace one and not the other? I have also learned that lack of progesterone can cause thyroid problems. Sure nuff, went to have labs done and my thyroid is low. I will be starting progesterone next week. I too had a complete hysterectomy(still have ovaries). I am on the pellets now, but still have depression, anxiety and some panic attacks. I’ve never in my life had these problems. The pellets do help a good bit, but I am going to add progesterone to see if it helps me more. I hope you get better soon

[@angelinadrobina5037]

@@tesiemarie8942 and you 🙏🏻💛💛

[@juliaantos4605]

My PCP gave me the name of a Menopause Specialist because I was having trouble sleeping. She said I could either get sleeping pills or try HRT. I took the name of the Menopause Specialist and made an appointment 2 months ago.

[@drsusan]

Menopause.Org is a great resource and we would be happy to see you here either in person or remotely

[@lacolora]

New subscriber here....I'm so frustrated because my Dr. will not give me a prescription because I have a history of breast cancer in my FAMILY!...There's so many new researches that state that it's ok to use. My biggest concern is Vaginal Dystrophy, everything else I can live with. Any suggestions would be much appreciated!!!

[@tc4585]

Estrodiol cream. Twice a week.

[@mazeygirl2408]

Did she ever talk about injections? She mentioned it in the wording on the screen but never discussed it. I have not ever done the pellets and the reason why is once you do it your stuck with it for months. I agree with some of the other people on here finding the right balance is definitely the key. Going to talk to my FMDr about injections, which gives me more control. I had to have a complete hyster at 23 and 55 now so I have tried alot of things that have just been meh.

[@msmc2685]

Best way to get a close to correct dose of T would be using TCyp 200mg/ml and use a tiny bit of that. Inject 1/10 of man’s dose 2x week. I use a compounded TCyp that’s 50mg/ml and injecting 9 mg a week divided in 3 small doses a week.

[@janmartell9792]

I'm 66 yrs old and have been on bio identical hormones for about ten yrs. Originally I used capsules which took my hot flashes away. I switched drs and she prescribed creams. Ever since I've used the cream my hot flashes are back. It's been two year now. My dr says my levels are good, as of saliva trsting. Do you have any idea why I'm having hot flahes since stopping the capsules?

[@drsusan]

Hot flashes mean your estradiol level is too low. I would suggest trying a patch. There's no science supporting using saliva testing and if you're having hot flashes, then your levels are too low no matter what your doctor tells you.

[@Andrea-64]

I finally got hrt after 10 years of trying. Been on for a month and a half. I now have severe osteoporosis. I'm on estrogel 0.06 progesterone 100mg. Still have hot flashes brain fog poor sleep and extremely exhausted day and night. I've asked for the estrogen to be increased but I'm being ignored. I'm low income so I won't be going to a compounded pharmacy. I live in Canada.

[@patriciadrank6543]

I can see that you really like the pellets. I have to let you know that I had a bad experience with these. On my third Injection of the pellets I had 2 issues. The pellet was inserted incorrectly, and not only was it very painful for a couple of weeks but, I started bleeding as in having a period when I was 65. The doctor told me that I should just have a hysterectomy. Keep in mind that when I started these. I had no issues. Needless to say, I never went back to that doctor. I am estrogen sensitive, and she wasn't willing to work with me. All that she wanted to do was surgery. This would have been a money maker for her. So I have had no help with hormones and now I am 70 with osteoporosis.

[@MarianneWilkinson0312]

Dear Patricia - so sorry you went through all that ! Please continue to seek expert doctors on KZbin - there are several that have made it their mission to help educate woman of their options. Some do consults.

[@melgun13]

Loved this video. Thx for getting into the weeds regarding dosages. I recently started estrogen patch 0.025 with amazing results immediately, but when it was time to add the progesterone (200 mg for ten days) it felt like too much causing some GI symptoms and reducing the estradiol benefit. I was two months shy of menopause and getting close to 54 in age. Initially I was miffed to not be put on continuous being so close to menopause, but it gave me the chance to see how I felt on E alone first. Should I ask to have Progesterone lowered to 100 or is this not recommended in cyclical? I just haven't felt the same since the first 10 day cycle and not looking forward to the next one. I feel like the P is having a negative effect on my digestion, when the E greatly improved it.

[@bluejean-1968]

Oral progesterone caused digestive issues with me, as well. I'll assume you are talking oral P. What I do is order 5% progesterone cream from Ona's Naturals (1/4 tsp is 62mg) I'll take 100 mg twice a day. No prescription needed. The cream does not cause digestive issues. I used to need a prescription for my compounded progesterone cream, but then I found Ona's creams. They are much more easily absorbed because of the small percentages they have of 3% & 5%. The 10% & 20% creams do not absorb well so don't order them. If you doctor doesn't put you on continuous progesterone, then just buy progesterone cream at Ona's and dose yourself.

[@melgun13]

@@bluejean-1968 thanks for the suggestion. I doubt my Dr will go for this as there isn't much literature supporting creams for uterus protection. Hopefully with the increased funding going towards women's health we'll have better answers in the not too distant future.🤞

[@bbenabe]

I’m on 100 and it’s working great. I take it right before bed.

[@jenniferenage9263]

@bluejean-1968 are you on estradiol cream as well? Thanks for this info.

[@LeighClark-zf8oi]

What do you think of labial compounded cream?

[@drsusan]

Great locally for dryness - but doesn't get got your system to help anything else

[@MrDandelio]

No one seems to talk about the fact that our hormones cycle even after menopause. My hormones cycle weekly (the same way as in monthly menstrual cycle only shorter ) . I thought having a patch and progesterone would smooth it up but nope! The same cycle happens , and I still go through severe mood dips, bone pain and sleeplessness during my ‘period’ two days a week ( sometimes even cramping and spotting). It drives me nuts because I’m very unstable. 🤪

[@melissab467]

Does the transdermal dose reflect the actual absorption rate? Transdermal applications are not 100% absorbed.

[@bnb97a16]

I am on .05mg estradiol patch & 200mg micronized progesterone. My serum estradiol is 54 while my serum progesterone is 0.3 so my NP wants me to increase progesterone. The 200mg progesterone makes me sleepy even the next day & I actually felt better on 100mg progesterone so I don’t know what to do!

[@amyphillips367]

I’ve done estradiol gel and patch. My body did not absorb it.

[@sheilamccurley7084]

I have been on pellets for 7 years. My doctor gives me a slightly higher dose of testosterone than estrogen. I have found that my BHRT has stopped night time incontinence.

[@susanhudson5371]

It was determined back in January that at some point I had had a subacute stroke. I am 63yo and previously took Estradiol .05mg for the past 10-12 years. I was told to stop that medication since it can cause strokes. Now I am not sleeping well and have terrible night sweats. I can't get Veozah because my insurance doesn't cover and it would cost me $500. Now I am taking Paxil but it's not helping much. What are my options?

[@drsusan]

Non oral estrogen does not increase risk of stroke. That's misinformation:)

[@ImHandlingIt]

22:20. But if it’s giving me negative symptoms, I can stop taking it. Can’t do that with a pellet.

[@chemistryofwellness]

What do u think about estriol? It's hardly mentioned....

[@michellewilson1221]

can you give your thoughts on Bijuva? I take it because when I used an estrodial patch and oral progesterone, I had gastritis. Taking Bijuva doesn't cause it. I am not totally sure which one did it but I am assuming it was the progesterone since it was oral. What would you suggest to a patient like me to take? Patch and progesterone???? I am on testosterone shots and do well with those. I used to use pellets, but I need to be on something that insurance covers... that's actually why I haven't come to your clinic... need to go through insurance :)

[@drsusan]

I have no experience with that product :)

[@susanvanputten492]

Also, I had a primary tell me oral estrogen was the only way to get heart protective benefits! I stopped b/c my estrogen plummeted into post menopause I couldn’t keep my estrogen levels up with a pill.

[@BreindelPhotography]

If you check the blood level and it's a crazy high or crazy low level, what are you going to do? It could be a different level when you check again later the same day

[@l.beukema8570]

I am curious how to come by pellets in the Netherlands. I am now on patches, I am interested in pellets. How would I go about that?

[@drsusan]

I am not sure if they're available overseas you would have to do some research

[@julienelson7082]

I'm confused with one of the last things you said. Go to Australia to get testosterone cream? My doc prescribed testosterone gel here in the states. Is cream harder to get than gel? Come to think of it, you never mentioned gel form. ????

[@drsusan]

You can get anything compounded ! my suggestion was if you were completely opposed to compounding we have no other option then to use male products or go to Australia

[@julienelson7082]

Thank you! That makes sense.

[@carolanncoleman137]

Taking estradiol patch . O5 testosterone crème by compounding and 100 mg progesterone by mouth, curious as to how I would know if I need more progesterone since you said 100-200 mg/it’s hard in Mi to get a menopause specialist, went to 2 drs and one stopped answering the phone, who prescribed these but told me to stop preglanone and dhea, the other dr said no don’t stop them. Who do you think is correct?

[@drsusan]

100 mg is the minimum dose that has been studied to prevent uterine cancer but some people take more than that if they need it for sleep or moods or anxiety I personally take 200 mg but anything over 100 mg is safe Would be happy to see you remotely or in person to discuss

[@carolanncoleman137]

@@drsusan I would like that but when I called your office some months ago they said no because I lived in Michigan. Is it possible? I asked my combination naturopath/MD office for the doses you recommended and they agreed to give the prescription. So far I feel fantastic.I don’t know if can put my email here since not sure who will view it. I’m Carol Ann

[@netlane100]

Would you recommend to take estradiol continuously or 3 weeks a month? My naturopath believes, that continious hrt can give a risk of bad estrogen metabolites, so he also suggests to take DIM and brocoli extract. What do you think about it?

[@drsusan]

You've been making estradiol all your life -continuous estradiol is the standard of cure. That's what I recommend. You've never had a time in your life when you took a break from it so I don't know why that would be suggested. If you're using estradiol, that is the same stuff you've had all of your life. There's no need to take any products to worry about any " bad metabolites". This is biologically identical to what you've made since you were 12 years old.

[@netlane100]

@@drsusan Thank you very much!

[@jackiecoupland3620]

But what a sad about taking them to protect from estrogen disrupters in environment?

[@valkimpton5566]

Dr Hardwick, what is the type of measurement used for estradiol you use? is it picogram per millilitre? (you recccommend for ex. 40-80 but please add the rest! I am in Canada

[@nireeburr]

Hello & CAN U HELP PL…. Thank u great video session. 💯 I’m trying to understand this question. Coz no one can help me . I’m more emotional than ever before.. But I’ve gone thru the top 5 worst traumatic events other than war ( I’m so sorry to those whom are 🙏🏻😪) I have CPTSD ADHD DEPRESSION SOCIAL ANXIETY & grieving the loss of mum to cancer and a family who have rejected all of me coz they don’t believe anything about me. I don’t see them before this , but now I’ve cut that cord of constant disgust etc .. plus thyroid levels all over the show due to the above. I can’t get any help at all here.. partly coz I’m too scared coz family don’t believe me.. my body has gone from fit loving life, fair group of friends to none. Just dog and I.. I have panic attacks leaving the house every dam time.. So I took myself to dr for blood test . I would think I was doing it to him.. I had possibly hemrods that day.. coz of itch ( TMI 😮) I told him all that’s here below. He gave me estrogel to rub . No dose ,no blood test b4 hand . I I have pins and needles in hands constantly. So i updated all vitamins after listening to hours of info .. that keeps it away so I could sleep if I ever can get in the bed.. to sleep. I digressed a lot sorry .. So the question is why when I used one pea sized amount of estrogel in mornings … within that day my body copies one of these things without a doubt … -1st one was what we call trigger finger, then it was tennis elbow or carpal tunnel wrist or shoulders freeze .. this comes about randomly and same random amount of time frame. This time my legs have fluid and right knee looks like I’ve twisted it and it’s fat puffy , stiffness to squat down or left leg .. power is gone.. the back of knee feels like it’s grown muscle . then I go make a dr appointment.. it either goes away totally as I’m arriving to his office.. or I show him and he has no dam idea.. types it in his records . That’s the visit to dr! my skin is so dry it cracks and bleeds ..my nails are like claws . When I’m looking down at them they look like they are lifting off toe nail bed. And doctor thinks there’s nothing wrong yet I feel like I’m in someone else’s body, thoughts and feelings along with suicidal thoughts every day at 2-3 pm.. I had my partial hysterectomy back in 2017-18.. I lost the plot 4 weeks after it. I’d stopped all my meds and no one informed me what to do . I was momentarily about to do something really bad at the time .. coz I was a mess & it was so loud ..the only way to stop was lights out. My good ace doctor call me to say stop don’t hurt ur self.. ur blood test and numbers are off the charts .need new ones and estrogen was 890 or close to 900. She was shocked . Told me was I feeling like dying at that moment.. Yep I was in progress for disaster. Now with all of this .. one would expect no clinical notes are shared with drs as req.. like now .. I don’t think I need it but coz of all this stuff happening Estrog will make me feel better and help with skin. BS . & can u help at all . ? I have my last blood test results and did all hormone testing today.. can u help a desperate lady in Australia who’s using all compounding hormones and thyroid meds 2 stay alive..

[@claudiaformolo6535]

How do we know our estrogen is too high or too low? I thought in Peri menopause one experiences symptoms because the levels start decreasing... but mine is at 269 and according to my obgyn is way too high. She wanted to treat me with birth control pills instead. And I'm having terrible symptoms. After a lot of push back I convinced her to get me started on a low dosage, She put me at 0.0375 mg.

[@StrideOrDie71]

That was your number on one day. It could’ve been 50 the next day, then 130 the day after that. This is why we need to go off symptoms and not blood levels. For me, if I’m too high I’m anxious and manic. Too low and I’m depressed. Took a lot of trial and error to get me at the right dose. How are you doing on the .0375?

[@13nlsc]

But what about if we still need to take progesterone orally?