How mRNA Vaccines Work - Simply Explained

mRNA vaccines have to potential to end the COVID19 pandemic. How do they work? Are they safe? And how could they've been developed so quickly?
The main idea of mRNA vaccines is to trick our bodies to produce part of a virus. This kickstarts our immune response, without getting us sick. All that's needed is a part of the virus's DNA or RNA, packaged into mRNA. Cool!
(mRNA is the technology behind the vaccines from Pfizer/BioNTech, Moderna & CureVac)
💡 Follow-up video
• mRNA Vaccines: Questio...
I answer 10 of your mostly asked questions (and address some misconceptions).
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☝️ This page also contains answers for frequently asked questions.
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#mrna #vaccine #covid19 #simplyexplained

[@scofah]

I really appreciate how you didn't have any background music or sound effects in this video. I'm so tired of all the noise/racket in the background of videos.

[@The_mountaingirl]

True💯💯

[@wolfthorn1]

too true. Nothing worse than a two minute intro of dubstep at level ten.

[@jeffreyperez2178]

Oh my gosh yes!

[@michaelackerman8455]

I cannot agree more. I find background 'music' so irritating and intrusive that I am unable to watch the video. This video was brilliant, thank you very much!

[@syngen462]

Yes, and 2 vaccines and 100 boosters later!!

[@walkerb392]

But why we also hear people still experiencing symptoms and other illness after getting mRNA vaccines..??

[@john-cp8kx]

The problem is that spikes circulate in the blood and the complex of spike and antibody may deposit itself on the cells of blood vessels causing an inflammatory reaction that damages the cells lining the blood vessels.

[@panamahub]

so basically you don't need the whole enemy to train your soldiers only show them how the enemy's weapon look like.

[@simplyexplained]

Haha yeah! Cool analogy!

[@giovanigalagnara]

If your immune system will not react the spike you now produced more coronavirus. Can you have a presentation using DNA.

[@Memphis2010GFC]

Absolultely!

[@Memphis2010GFC]

We need to keep things in perspective. About 54 million covid vaccine doses have been given worldwide. We would all hope that no one experiences any side effects from the vaccine. I suggest the incidence of serious side effects is rare! It is very easy to highlight cases and blow things totally out of proportion. Which is greater: Getting a severe side effect or getting covid (which has known long-term side effects) and passing it on to others? What is your solution to getting out of the pandemic?

[@fareli91]

More like showing a photo of their enemy rather than just their weapons, and rather than letting them figure out by themselves.

[@Jurassiic]

At 3:05 it says you don’t get sick but many people have gotten sick with the injection , how come ?

[@goodvibes1525]

You don't get sick as in you don't get sick with covid

[@Jurassiic]

@@goodvibes1525 but people with the vaccine have been getting sick with Covid and the different variants.

[@Dish.Washer]

The symptoms right after receiving the vaccine are common responses when your body wants to build immunity. Getting the vaccine doesn't make you invulnerable, just like wearing seatbelts doesn't mean you're not getting hurt if you crash

[@HaloAubreeMariee]

It's symptoms, but not full blown sickness (most times). Your body is producing active virus DNA, so when your cells replicate it, you might experience symptoms of the virus before your body can shut it down. And by the next day, you're usually a-okay again.

[@andrewhate5925]

Why do we need second dose if our immune systems already know that thing

[@MjoedDrikkar]

B cells doesn't last forever, and if it is a reocurring experience your immune system will increase the amount of b cells in total in your body.

[@goodvibes1525]

Many vaccines have a second dose

[@D_B_Cooper]

*10th dose

[@Praestantia]

I swear the thought process that went into these vaccines was clever as hell. Like, who thinks of using our own body to make the key markers of a virus which it will use to identify said virus? That's the most ingenious piece of biomedical engineering idea I've ever heard of.

[@reveal102]

It is clever as hell. Some have likened it to the invention of the transistor.

[@outdoorsrob3023]

But with so many variations one will need booster after booster.

[@SamuelBakutana]

Clever as HEAVEN. Hell isn't that clever.

[@BazzaOTW]

I believe the originator of the mRNA idea struggled to get funding or anyone interested, until of course until COVID came along…

[@BazzaOTW]

@@reveal102 Nobel Prize stuff for services to medicine and humanity in my opinion.

[@Vearyn812]

wow, not mentioned any risks, only the benefits. Bravo

[@davidagiel8130]

Spike proteins themselves can still cause lung damage and blood thickening.

[@talltree3941]

💩

[@awayfarer6813]

@@talltree3941 like, oh 💩 !!!?

[@talltree3941]

@@awayfarer6813 no, like this guy “David” is trying to push some bullshit story to try to scare people from getting the vaccine. So the emoji is meant to mean “bullshit”. But maybe I coud Try: 🐂💩

[@awayfarer6813]

@@talltree3941 Haha, well, I just hope people are doing their due diligence and homework about the vaccine before making a decision, and not stopping at this simple video. I respect whatever personal decision people make...and what I mean by personal is thinking for oneself, and not giving in to coercion or societal pressure either way you go.

[@talltree3941]

@@awayfarer6813 I got fully vaccinated in March. No issues. I live in a large city. Millions have gotten fully vaccinated. I haven’t heard of anyone experiencing any serious side effects.

[@carolejackson8357]

Good simple explanation but missing important parts like how does the body stop this loop of continuing to make the spike proteins. And what are the long term affects.

[@BJ-Hunter513]

Long term effects? It's still in Experimental stages

[@GQ-yb5kt]

Great vid! Straight to the point, easy to digest, and quick. Literally everything i needed to know!

[@conniemcmurray5146]

I think it is misleading that the video didn't make clear that the vaxxx is meant to kill us all.

[@the_modfied_car4903]

@@conniemcmurray5146 go back to school

[@CarlosVAsquez-kp2qf]

@@conniemcmurray5146 so where are all the millions of dead people?

[@Chipchase780]

This is the best and clearest explanation of mRNA vaccines I have heard so far. Excellent !

[@simoneharvey-foote9134]

seriously !

[@temusombash4256]

Very good indeed!

[@funkyfreak97]

Better than my coworkers over a Skype call this morning. "mRNA will fuse to your genes and kill you." I'm still speechless. These people get paid around $25-40 an hour and they think Bill Gates is trying to microchip us. I only realized this morning how nutty a couple people on my team really are.

[@DaniDani-zb4wd]

@@funkyfreak97 Isn't 25-40$/hour quite a bit even for well developed countries? 25-40$/hour is a lot in my country where minimum net salary is 317 US dollars like imagine getting paid around1,5$/hour like not getting paid in a day of work as much as you get paid in one hour.

[@rrajkamal]

I agree 100%!

[@user-uy3eq5hg1s]

My concern is that this is the first time mRNA has been used on humans in such a wide scale before. The experts say it is safe, but how can we know for sure that there will not be long term side effects?

[@jonny555333]

Because we know exactly how it works. It's isn't just some random procedure. We have known how mrna works for decades and we simply are using that knowledge to teach out cells to fight off a virus.

[@maxmorris4562]

@@jonny555333 we don’t know the ramifications and the majority of us can fight off the virus with our immune system so we don’t all need it

[@Mnpat]

@@jonny555333 no, this has never been done before on humans and everyone gettin it are guinea pigs to fight a virus that’s 99.998% survivable!

[@whyp9552]

@@Mnpat lol if you don't have a good resson to get vaccinated (like a disease or whatever) and you don't want to be vaccinated you're irresponsible and more or less an idiot

[@caryfrancis8030]

@@maxmorris4562 we know how RNA works, my buddy began working on this more than 20 years ago.

[@garydean777]

If it is that simple then why are there so many people suffering severe side effects & why are so very many reputable & highly qualified doctors warning us not to take it? I don't get it.

[@theotherorange3586]

I don't think I like the sound of this. What happens when it mutates in your body? Your infecting yourself with something that might cause autoimmune disorder by the looks of it. I will take my chances with nature

[@garydean777]

@@theotherorange3586 A lot of doctors have said precisely that.

[@SreeOne]

I gave thumbs up for the last part of your Video. Dont just trust me, deep dive into the sources. Nice .

[@gailbenton8642]

Sources: Forbes, Wiki, Business Insider, Twitter?

[@Kelsie_Lista_Brinza]

My concern is by sending a message to your cells to replicate the "spike" and then to later attack that spike could be setting our bodies up for autoimmune disease.

[@slooob23]

Which might not materialize for many months or even years later. I am not taking an experimental medication like this until it is proven safe.

[@kenn3758]

The mRNA that tells our cells to produce the spikes are very unstable. They are degraded very quickly and does not remain in your body long term. It is only temporarily there to teach your cells to recognize the enemy. It's like how you would teach maths to kids , but you're not going to stay with them the rest of their lives to show them how to multiply.

[@slooob23]

@@kenn3758 all you are doing is describing the theoretical mode of action and the intention of the medication. What happens in real world situations is unclear at this stage, though people have already died after taking this experimental medication. Describing the intention is somewhat meaningless in this context.

[@kenn3758]

@@slooob23 I understand your point of view. Though I must highlight that this 'theoretical' mechanism has been well studied for decades, meanwhile the deaths (if any) from this category of vaccines are extremely rare. That is like saying you won't walk outside during the rain because lightning could hit you. Yes there may be a slight possibility of negative effects, but the expected benefit you and your community get from this vaccine heavily outweigh them.

[@slooob23]

@@kenn3758 to my knowledge this is the first RNA vaccine ever produced, in that regard how can we have high confidence in it until a suitable period of time and the associated monitoring is complete? We also don't know how long it is effective for, corona viruses being notoriously difficult for lasting immune response. If the vaccine is only effective for a few months the risk profile becomes rather more of an issue.

[@Christophers_Crafts]

Then why are people getting so sick after the second dose?

[@PinkeySuavo]

1) So why more than 1 injection is needed? 2) Why there are any side effects or people feel sick and so on? 3) Why there's a talk about "long term side effects"? How learning the body to fight against virus can cause long term side effects?

[@coleross1562]

you can find these all with a simple google search

[@PinkeySuavo]

@@coleross1562 but im too lazy

[@xxkq0]

I had the 2nd dose of Moderna recently and had pretty bad flu symptoms for about 24 hours (headache especially when moving quickly, muscle pains, fever, skin sensitivity, fatigue etc.). This video says there are few side effects because there is no live virus but side effects are pretty common at least for Moderna and Pfizer, so what is the mechanism that causes this? Immune system overreacting to the spike proteins?

[@Banishedsoulsofficial]

MRNA is a retrovirus. When a virus Is replicating it needs certain conditions. A fever means it is doing what it does to replicate. It's not a vaccine by definition it is infact gene therapy using a man-made retrovirus as a delivery system. You really shouldn't do the boosters, you shouldn't have done the covid shot at all. But that is your choice and you made it

[@adama9032]

To much misinfo thanks for clearing it up

[@thesmiffable]

@@Banishedsoulsofficial You are suffering from what's called the Dunning Kruger effect... you think you understand the whole picture but really, you're clueless.

[@thesmiffable]

When someone can't type mRNA properly, it's a dead giveaway of where they are coming from.

[@cwdgamedev1017]

@@Chad_Max I recently watched a talk given by a biochemist who worked at Pfizer for 10 years. He said that there no attenuation (that he was aware of) of the vaccine's effect, which is to cause cells (which cells?) to produce the spike protein. Once you're injected, your body will be producing those spike proteins indefinitely. And since they're so small, they are able to penetrate the blood brain barrier. This leads to clotting (strokes) and inflammation elsewhere in the body. Your body will constantly be fighting to eliminate them and it likely won't be able to catch them all. They're going to build up and we're going to see what the long term effects of that are. It's probably not going to be pretty.

[@tumnaharring5233]

Thank you so much.. saved me from failing in my Final school year Bio Examinations ... Hoping to get at least 90... 7 questions from the subject came and I answered it will thanks to you

[@MacLuckyPTP]

You will not get 90 if you take vaccines frequently.

[@stellarch9524]

@@MacLuckyPTP what?

[@SHREDTILLDEAD]

@@stellarch9524 you will not live to be 90

[@stellarch9524]

@@SHREDTILLDEAD I like how you didn’t even correctly explain it, this guy is talking about grades not the age so your clearly just as stupid as the guy I replied to

[@lunamoon9935]

One of the best explanation videos ever!!

[@JoannaLaurensings]

So if you can’t get sick, why are some people getting symptoms after taking it?

[@revelations4396]

I like your explanation. However, it must be cautioned that this technology does not have a track record. What will happen when this synthetic rna is produced in other parts of the body? In the case of covid, what about the lipid enclosed nano particles? They are basically tricking the cells into making a synthetic compound. What is being used to create this synthetic compound? What happens to the synthetic compound that was used to create this protein? Can the nano particles be remotely manipulated? How is it possible for the vaccine to enter the cells?

[@PD-yd3fr]

@@renitapayno Jerusalem Times had an article about these mRNA vaccines. I am not an antivaxer I know vaccines work, but this is an entirely new type of vaccine, never been approved for use in humans before. I don't know why they would not used the tried and true weakened/dead virus for a vaccine

[@revelations4396]

@@renitapayno , do you mind sharing that article? I have too many questions about the platforms that they are using with this vaccine. I personally find the whole process very troubling. No one is talking about the nanotechnology used in this vaccine.

[@3274BigBlueBotics]

Tried to warn coworkers against using this new technology that, ultimately, injects itself into your cells and manipulates them to produce spike proteins instead of what it normally produces. Extremely invasive. Most importantly, I said it's not worth taking a risk given you are young and healthy and are at no risk. Of course, they called me anti-vaxxer.

[@tonymak9213]

So that's the theory. But what about all the spike proteins travelling around the body and causing mayhem in vital organs?

[@A3Kr0n]

Listing sources gets a huge thumbs up.

[@JoshxIZ]

You get a gold star if u get ur 2 injections :)

[@shadowman7408]

Still doesn't explain what happens to the cells that manufactured the mrna.

[@thomask2616]

Thank you, most articles act like I am a child when I read them.

[@simplyexplained]

Glad you liked it!

[@fidyculous]

That might be because most of the people are behaving like children during this whole pandemic

[@cindysagers9552]

Wonderful! Thanks for the straightforward explanation. Brilliant!

[@sophielowe1417]

Thank you for taking the time to simply explain. First video that I have found that actually makes it clear and precise.

[@ManufactureBelief]

Please explain how it is impossible for the synthetic mRNA to enter the cell nucleus. I've not seen any explanations on why this is impossible anywhere. They just say it's impossible. As a commercial risk analyst my role requires me to list all the possible risks (even unlikely ones) for any large purchases/contract agreements that need approving by the exec. This is so they can make an informed decision. No one is giving any detailed listing of the risks, including 1, 2, 3 - 5, 10 year and longer term horizons. What are the potential risks, however unlikely, if its even remotely possible, they should be listed so we can make an informed decision. If execs expect such for a mere $1 million purchase, what makes this any different?

[@AstralPhnx]

Incredible video explaining some incredible technology! I'm amazed by the scientists that managed to come up with this technique and put it into effective use! Incredible stuff!

[@garryallison5679]

I wouldnt get to excited. Lets see how it works a year down the line.

[@nickizcool20]

@@garryallison5679 it works great

[@nickizcool20]

@@garryallison5679 I got the vaccine it’s awesome. I feel great

[@3chords490]

@@nickizcool20 the placebo effect....

[@AC-lh3qb]

why are people dying from the vaccine?

[@xxsexhaverxxreal1180]

You can tell if someone is really smart they can explain complex things simply with ease.

[@sweetbeat7]

asking the body to build lots of spike proteins? teaches us how to fight them off? may make sense to some but not to me.

[@camokoy]

The really smart people never took the jab in the first place

[@yako668]

If developing vaccines takes about 8 years to get approved, how comes that the CoronaVac vaccine or Sinopharm which were developed using the traditional method, got approved for emergency use in less than a year?

[@findyourpassion8722]

I love your ability to Simply Explain complex topics. Subscribed.

[@TheMicahwitz]

Talk about the side effects now.

[@melanie8388]

I've been trying to find a clear and simple video to show friends and family, this is perfect - thank you!

[@manu23325]

Nice explanation, but I still don’t understand how the immune system understands that those produced spikes have to be killed, as they don’t cause any harm.

[@djl9154]

Nice explanation and appreciated. The part about not getting sick is not quite accurate though. Maybe that is supposed to work that way, but typically doesn’t from all that I talked with, at least a few days. One study even indicating that the spike protein may be getting in the blood in a few cases, anything can take place if that happens. Guess will find out over time.

[@tslavens3092]

Exactly

[@almomedvedec896]

As time passed we found out in a very concerning way

[@swayp5715]

Thank you brother!

[@mahavati3696]

Well that shattered one or two illusions I had! Thanks for that video.

[@tdottees7146]

just like that huh? did you bother to research further? probably not...

[@randyrandall8274]

@@taraakins8273 Whaaaat? Wow, just....wow 🤦

[@AdamNZ]

I had the worst reaction from my second phizer vaccine and so did my partner.

[@Mr.Monta77]

You don’t know why that happend. It could be something else that caused your reaction. Don’t make the assumption that because two phenomena occour simultaniously, that one is caused by the other. That is a logical fallacy. It could be the vaccine but to claim it is a mono-causal and often erroneous explanation.

[@StefTechSurfer]

Now Govts need to market this with a brief explanation of how the vaccines work and endorsements.

[@MrStruggle0]

Exactly, they’re currently just advertising that you should get it and that everyone’s getting it, instead of actually explaining it so people can see it’s safe without having to take the governments word for it

[@kasiawilk39]

Nie,nie

[@BrandonTorres]

Really good explanation and super understandable, thank you!

[@screeneducation4167]

Except he didn't mention the following: 1. The purpose of the research Dr. Fauci funded was to engineer the spike protein to be EXTREMELY toxic. So the spike protein our bodies manufacture are just as toxic as the spike protein on the virus, and they are causing major problems. 2. It's the spike protein that is mutating to create the new variants, which is why these vaxes don't provide lasting immunity ---- after the spike protein mutates, our immune system no longer recognizes the spike virus. Which is why dead antigen vaccines are so superior --- because we develop immune recognition to all 32 viral proteins, so when the spike protein mutates we can still recognize the rest of the virus.

[@maurakoulik982]

Great explanation and graphics!

[@asymmetricfuzion970]

Dude. Thank you. I’ve recently got the new kurzgesagt book on immunology. It’s great but I either haven’t got to the MRNa but yet or it’s not covered. But I keep hearing about it and I keep hearing about “MRNa entering the cells nucleus” which sounded like bullshit. This totally clears up what the MRNa does so thank you 🙏

[@timstimbre9762]

Awesome, couldn't find any info on the actual breakdown of the produced spikes by the body's immune system after vaccination has taken place. This was clear and concise for laymen like me. :-)

[@lolli2943]

Me too

[@tgy119]

In North America, why is the government not procuring traditional vaccines from Russia or China. If I had a choice, I’d much prefer the traditional weakened or dead virus vaccine over mRNA version.

[@Subfightr]

I HAD the same feeling as you. For me, an mRNA engineered vaccine was new, I didn't understand it, thus I was afraid of it. But when I took the time to watch several hours of videos from the engineers themselves, it was fully explained, the theory behind it, the amazing mechanism used to create it, my fears were lifted. Let us not go back to sleeping under the covers because we are afraid of the monster in the closet, I feel it we were to shine a light on it, we would see our fears are unfounded. I appreciate that you have watched this video at the very least.

[@pushandr_]

Well if you google how Russian, most of Chinese and also Astrazeneca/Cambridge vaccines are made you will realize they are not traditional at al :) They all use an adenoviral vectors to achieve basicially the same what the mRNA vaccines are doing in this video, but with some extra steps (DNA to mRNA transcription) . This vaccines are basically give you an infection with genetically engineered adenovirus (usually in nature this virus is responsible for the common cold), that unable to replicate because of deletion of many important genes in it, they just use this virus to deliver genetic information to the cells of your body, so they can produce some sars-cov-2 spike proteins and trigger the immune system. Still not sure which technology is better though, they all have pros and cons.

[@mahasimha8379]

Sputnik V, traditional no side effect vaccine..

[@pushandr_]

​@@mahasimha8379No, adenovirus based vaccines are quite new, it is completely different technology compared to your seasonal flu shot for example, please use google...

[@Urketadic]

In theory it sounds great, in practice its unfortunately not.

[@mackenmd]

You have done the world a public service by creating this video and I will share this to all corners of my little world and hopefully it'll spread. Thank you also for providing references in the description. Well done!

[@simplyexplained]

Thanks for your kind words! Really means a lot. I hope other people will also see the value (and the trolls stay away)

[@mackenmd]

@@simplyexplained You are very welcome. Ignore all the trolls and anybody else that doesn't have a constructive question or comment. I know, easier said than done. In particular, there is one person I will target this video to: she is a fitness/motivational influencer on KZbin and has urged her followers to avoid vaccines at any cost. I will be sending her your video link directly. Her chief complaint is the mRNA component of the vaccine. This is especially why I'm appreciative of the references in the description. Keep up the fantastic work!

[@martyes9563]

Spread...like a virus!? (Sorry, little vaccine joke)

[@mackenmd]

@@martyes9563 we need laughs so no need to be sorry ;-)

[@chanfranc]

Hope this video will calm down the anti-vaccine people.

[@elizabethhurtado2829]

What if a person already has a hyperactive immune response and how long dies this stay in your body and what is the connection to heart and kidney disease?

[@manon8600]

if mRNA vaccines can't make us sick, how come a lot of people experience covid symptoms (fever, fatigue, etc) a for a few days after vaccination? (not being edgy, just asking sincerely)

[@morris5439]

I wanna to know what kind of body cells will take up those mRNA? Are those cells being specifically selected or randomly absorbed? Once those body cells start marking the viral protein and display on their surface, will the T-cell treat them as foreign and attack those cell also? Just like rejection in transplantation?

[@azaraliyev2064]

Good question and it is about 4 days no answer)

[@morris5439]

@@azaraliyev2064 Either no one can give the exact answer, or someone know the answer but not wanna disclose it.

[@bemusedbandersnatch2069]

I've been wondering about that too. I would assume they're just thrown out of the cell to hang out in the tissues or work their way over to the bloodstream where immune cells can find them. (Cells absorb and release proteins all the time after all.)

[@clarity2371]

Thanks for sharing! Finally some clarity : )

[@haydenmacfarlane7194]

Thanks for the explanation. Easy to understand and relatively quick/to the point.

[@simplyexplained]

Glad you liked it!

[@theorialogos]

Very good explanation, thank you. Many people I know who get vaccinated get sick almost immediately with covid type symptoms. Why is that?

[@jear4766]

You really make it easy to understand. Thank you so much!

[@dan4091]

Good, now we know how it is **supposed** to work, but what are the possible downsides to teaching the body how to make spike proteins.

[@martymcfly5423]

what about all the thousands of people that already died within 24h of taking the shot?? 🤔

[@Kevo-vt5di]

great video. I have two questions: 1.) So if your cells are constantly creating the Spikes from the virus, and your immune system is constantly destroying the spikes, does that mean that your immune system is constantly in fight response? 2.) So if eventually your immune system destroys the Spike RNA in your cell, does that mean your immune system attacks your cells to get to the Spike RNA? How does your immune system destroy the spike RNA in your cell l if it is encoded into your cell?

[@Cajaquarius]

1) Once your B cells have the memory of the spike and the mRNA they quickly isolate and destroy the afflicted cells and remove the alien material. 2) Once isolated by the body, the cells making spikes are injected with enzymes that cause them to undergo self destruction. This is commonly how your body fights and gets over the Cold and the Flu.

[@beetlejuice1209]

@@Cajaquarius I bet you think you're pretty clever but you didn't answer the questions properly but I've got a question for you: 1) How long will your body keep making these spike proteins? Just until your B cells have memory of it is it then you stop making the spike proteins or do you keep making them for A week, A month, A year, decades or the rest of your life? I anxiously await your answer as the clinical trials are still ongoing and so 'They' dont even know yet until 2023 when the trials end...

[@Cajaquarius]

@@beetlejuice1209 Until your B cells have a copy of the protein and make antibodies against it. At that point, your body can instant detect and destroy cells infected with the viral RNA. That is pretty much how all vaccines work and also why you never get the same flu or cold twice.

[@beetlejuice1209]

So you're saying once your B cells recognise the spike protein your body stops producing it, yeah?

[@Kevo-vt5di]

@@Cajaquarius 1.) So you are saying that your B cells only attack the cells that are encoded with the spike protein of the virus? I thought once you get the vaccine, all your cells produce the spike protein. The only concern I have is that this new vaccine may cause Autoimmune diseases, especially in young people that have a more active immune system than older people. Thanks for responding.

[@preetcharan]

The easy going explanation so far.

[@ribbtmcabe8459]

Could you please explain *which* cells end up manufacturing the spikes? Just the muscle cells at the injection site, or does it affect blood cells, or something else? Also, when the cells manufacture the spike protein, do they display this protein on their surface, or do they excrete the protein? Do these mRNA-containing cells get killed by the immune system? Thank you.

[@farshads3367]

Thank you body from Iran. In Iran Moderna and Pfizer are banned! Most people just cheer but little number of them question! The mRNA gets destroyed inside the cell after the cell produces the spike protein.(that's generally how it works with messenger RNAs) "Which cell types end up manufacturing the spike proteins?" Exactly! And they don't seem like talking about it without having their videos and articles removed or censored or not being ordered in google search results! Disgusting! "Do they display this spike protein on their surface, or do they excrete the protein?" Exactly! According to the scientific and official articles I have read, they appear on the surface of the mRNA-targeted cells. This means those cells can be targeted by any type of viruses that use that specific spike protein to inject its genome to the cell for mass production. Like a channel under the walls of city that can be abused by any enemy who knows that channel. From 5:52 of this video it expresses as if the spike proteins are exerted from the cell!!

[@deathstr1ker6666]

A lot of it goes to the liver and spleen.

[@bencorley8687]

Thank you for making this so easy to understand. It really does help give me peace of mind.

[@geraldinemyers7769]

Amazing and totally clear, understandable explanation of covid vaccines. No highly technical mumbo jumbo that most researchers like to try and impress you with. A real breath of fresh air for anyone who wants to know what is happening inside them when they get that shot.

[@norawhite1503]

That's me right now. Just got the second shot so I am wondering what happens to see if I am going to feel bad or not. Amazing video

[@JohnDouqh]

Forgot to mention ade

[@H.K-tm]

Very true. Same here

[@telemarketer1584]

ikr? I watched one and they were like "fancy science words... blah blah" and I didn't understand a thing. This one makes sense! I think it's really important that people explain things in normal terms, so ordinary people can understand it too. Don't try to impress us with technical terms, impress us with a clear, understandable explanation

[@JohnDouqh]

@@telemarketer1584 for a better explanation on how these “vaccines” work. Just go to John Hopkins COVID tracker. Pick your favorite heavily vaccinated country (Israel, Canada, Australia, Gibraltar) look at the timeline of COVID cases and deaths. Notice how the majority occur AFTER the “vaccine” rollout . I’ll let you figure out what that means.

[@alanoliver9956]

The vaccine is mRNA. mRNA is genetic code. The vaccine is genetic code. He forgot to mention that.

[@MikesterCurtis]

The immune system is amazing. I think you could add to the video the effects someone might experience while the immune system tackles the intruder. But keeping it simple is a good way to teach, generally.

[@alland]

So, at 3:30 where it states that these B Cell memories hang around until the same virus infects you again - and presumably fight off any harm or infection - do we know if a person would test positive for coronavirus at that point? I would assume with the abnormally high 45 cycle PCR tests that this would be picked up and somewhat incorrectly classed as an ’infection’ or ‘positive case’? Appreciate any further info on that....

[@jordankeats8327]

Short and sweet, wonderful and informative video!

[@janecridland5105]

Perfect amount of information, explained concisely. Thank you!

[@keyring86]

People are still getting symptoms from the mRNA vaccine, although this video say they shouldn't. Why is that?

[@Mika-El-]

People are in fact dying quite a lot. Or getting disturbingly often very ill.

[@mialon5573]

Doesnt the immune system also destroy the cells that produce these spikes though?

[@Auraya1986]

As a virus a Spike Protein is used to dock on the cell, what happens with all the spike proteins that are now generated by the own body? Do they also dock on a cell or they just floating around in the blood?

[@sadismx2137]

They are supposed to get destroyed. That's the whole point of the vaccine, to train your body to recognize and destroy the spike proteins.

[@Auraya1986]

@@sadismx2137 the body is constantly producing the spike protein and destroying it? It sounds like war

[@sadismx2137]

@@Auraya1986 I'm not sure if its constantly producing it, as the mRNA containing those instructions is also destroyed along with the spike proteins.

[@TooOldFor]

How long do your altered cells keep pumping out spikes? And roughly what percentage of your cells are so altered by the vaccine? When these cells replicate, do their "children" also produce spikes?

[@jtothecc2421]

In theory and observation the mRNA is short lived so no. But other long term effects are unknown.

[@RealArtVandelay]

@@jtothecc2421 doesnt that scare anyone?? Hello? Isnt that a steep price to pay only to avoid feeling like crap for 2-3 days and have a 99.8% recovery chance???

[@romanval69]

@@RealArtVandelay It's a steeper price to survive a COVID infection with permanent lung damage, brain fog, loss of smell/taste, chronic fatigue syndrome that the survivors have to deal with after they 'recover'.

[@nicholaslindenmeyer6472]

@@RealArtVandelay I'm right there with you on that one.

[@heff4heather]

Wait, so what happens if your immune system starts attacking your own cells because they now contain the mRNA of the spikes in their own cells?

[@TravisJeScott]

THEN you have a pandemic

[@bluewaveafrica1092]

Lol

[@heff4heather]

Or is this not how it works, I don't know lol; is the mRNA lost during mitosis or apoptosis??

[@lucristianx]

With every mRNA vaccine I become closer to immortality.

[@seanpatrick2889]

The key is the B cell memory...and you didn’t say that immunity from recovery from natural infection also create the B cells....so...There is that.

[@79HBFerr]

How the body knows when to stop building spikes?

[@Tommy1marg]

cell producing spikes dies... oh wait

[@madhulikamadhu51]

When mRNA runs out

[@vgames6792]

that is a good question, 3:20 is it explain, but really is it? cell it self get cleaned??? and if not then what, my cell will be making some bulllhsittt spikes instead of something else?

[@inbaedae3733]

Better question, howcome mRNA are giving symptoms Especially on the 2nd shot?

[@79HBFerr]

@@inbaedae3733 Relatively simple: immune reaction (interleucines, interferon etc).

[@ibh9999]

Towards the end, the video man says "don't take my words".

[@vasilikitanousa7752]

Don't forget to watch what Dr Robert Malone (he contributed in the creation of mrna vaccines) has said about these vaccines

[@stephenvendryes2910]

Could you do a follow up on why some people have a negative reaction to this type of vaccine?

[@simplyexplained]

Already done

[@barryfox8703]

@@simplyexplained %

[@pigshitpoet]

@@simplyexplained so where is the link to the answer? this is not blockchain. this is a viral pathogen

[@fazeone1212]

@@pigshitpoet people are so gullible .. this explanation is so vague and simple its scary ..

[@soulbatteries]

Its getting censored too. All happy here.

[@courtneyc.647]

So helpful! Thank you so much for this video.

[@deliciosatv8401]

Yes, I agree with you. cool video! clear and easy to understand!

[@SmallFry01]

Amazing, super clear explanation. Well done!

[@progress-ms3du]

Very graphically & clearly illustrated - quick questions tho : 1. What is the synthetic mRNA (syn-mRNA) made from? 2. How & (more importantly) why does the body destroy the syn-mRNA? 3. How long after it's introduction is syn-mRNA removed. ? 4. Does this affect efficacy timelines ( hence booster shots ) ? 5. Does this removal of the synthetic mRNA from the cell have any destructive effect on the cell itself, either in the ribosome or the nucleus or indeed the whole cell? 6. For how long do the B-cells retain the infectant 'information ' ?

[@stefc7122]

Good questions. He also used the words DNA and RNA as if they were the same thing and I’m not sure why. I think the 2 places he does this need further clarification.

[@thepetyo]

Great. The only problem is as it turned out that the spike proteins on their own also make you sick. So I think that part of the explanation is simply not true. Anyone with some info on that?

[@TheRealColt45]

This was great! Thanks for putting together such a logical and simple presentation.

[@elizabethquintal2499]

Excellent video. So simple, easy to understand, informative and educational. Thank you! In fact, this video should be sent to the CDC so they can better inform the public instead of confusing them.👍👏

[@MegaTrivial]

Maybe their intention and point, is to confuse

[@mommyshark5106]

@@MegaTrivial yeah they want fear, not facts.

[@MegaTrivial]

@@mommyshark5106 - it sucks.. I wish authorities were starting to behave normal, no need of power over us LoL 😆😆🙂🔌🔌🔌🔌

[@izamils]

Thank you so much! This really helps me with my Life Sciences 11 Project!

[@DardaniaLion]

You got my subscription. Totally clear explanation.

[@TheLunarElixir]

Great video explanation! I still have questions though, like how is the mRNA destroyed after it enters your cells? When cells get infected by a virus and start producing copies of the virus, the immune system destroys the hijacked cells as well as the virus. What happens to the cells that used the vaccine mRNA after the immune system starts responding to the parts of the virus that it manufactured?

[@aloelivingwithesma]

Good question ! I hope someone has an answer

[@mickdonedee1]

I believe the mRNA has a short life-span and can only produce a finite amount of spike protein before it dies. The cell that hosted the mRNA will die when attacked by killer T cells that find the spike protein on the surface of the host cell. That's because the killer T cell thinks the host cell is an intruder (virus).

[@Tinky1rs]

Mick is correct, but I'd like to respond with another question to keep you thinking. Most cells in your body make proteins all the time. They do that based on the DNA in their nucleus. To make a protein, they need to send an mRNA copy of that code to the protein factory (ribosome) outside the nucleus. So my question: if all proteins in your body are made this way: where do all those mRNAs go? The answer is there are multiple ways to destroy mRNA after it has done its job. RNases (enzymes that cut them up), ones that untag them for ribosomal pick-up, others that tag them for destruction. This usually happens rapdly, so that the building blocks can be reused for new mRNAs.

[@mickdonedee1]

@@Tinky1rs It seems that cells have mechanisms to degrade mRNA to regulate the amount of protein translated by the ribosome. Heat also degrades mRNA.

[@Tinky1rs]

@@mickdonedee1 yeah, those mechanisms include RNases, uncapping, iRNA and even the sequence itself, as stability depends on the actual string of nucleic acids and what loops they can make. Heat definitely plays there too.

[@MiladFarjadian]

Thanks! Easy and understandable.

[@CALO65]

What they don´t say is that in many cases your body does not stop to produce spikes wich can lead to a zykotinstorm and autoimmune sickness = destroyed life.

[@jackjohnson4386]

They don't say that because it's not true. It's complete nonsense you've made up with zero medical education or basis.

[@user-nf1hm3ny6s]

This is such a great explanation! Thank you so much!

[@JoshxIZ]

This is great:) now u too can get this amazing injection from god.

[@bluesky5384]

Thankful for this video and the (majority) of comments being informed and intelligent for once.

[@rowanedy123]

The fact this doesn't have too many views has me worried about humanity as a whole...

[@288theabe]

Half million isn’t enough?

[@jarynn8156]

The anti-vaxxers are too proud of their ignorance to learn how it all works. After all, learning some basic biology might make them realize they were wrong. Can't have that.

[@jarynn8156]

@Jonathan Bacon-Sandwich Nope, but I know enough to understand the science behind how mRNA vaccines work. Its really quite fascinating. The folks screaming from the roof tops about gene therapy are, to put it bluntly, clueless. They don't understand what mRNA is or how it works at even a basic level.

[@tdottees7146]

@@jarynn8156 The anti-vaxxers are the ones that actually did their own research and came to the conclusion to stay the fuck away.

[@jarynn8156]

@@tdottees7146 Eh. They may have done their own Google searches, but lets not call it research. Very rarely are their opinions based on actual scientific evidence. They are based on pulling quotes wildly out of context, extracting numbers from sources that never proclaimed to have the numbers they are after, and, when all of that fails, just straight up making stuff up. I've seen so many people down here in the comments go on about everything from gene therapy to autism to fake quotes from Pfizer that the vaccine will cause miscarriages to claims that the vaccines are somehow the Mark of the Beast. All of which are absolutely devoid of fact. And since proving a negative is super hard, good luck ever reasoning with them.

[@vivekchandraundirwade7059]

Awesome explanation. Keep up the good work Champ!!

[@dongilpark2701]

Nice animation. I rarely looked at this quality video.

[@KingsleyOseiAbrah]

You really made this very easy to understand! Thank you!

[@c0d0r12]

You didn't mention that your cells, when creating the spikes, express them on their own envelopes thus becoming a target of your body's own immune system. They aren't just free floating proteins that get tagged by antibodies. Nifty little factoid to leave out as your body actually attacks itself when the antibodies are developed. This is why people are getting smacked so hard with side effects post injection. There have been all sorts of weird immune responses, not to mention cardiac stress.

[@christopherlocke9616]

Great point, I notice the agenda for this video is pro Rna vaccine. Wouldn’t mass production of the spike protein start opening all the cells at the ace? Those spike proteins are designed to stop immune response too. Also, this is not a vaccine. They changed the definition of vaccine in order to call it a vaccine.

[@arch3866]

yep that exactly happens. however, worse happens when one is normally infected: with the vaccine, it is controlled infection of cells. with normal catching of virus, one would have their cells hijacked unchecked, and would be self-attacked at a larger scale. its not really such a "nifty little factoid to leave out" since it is just not different from how traditional vaccines handle this.

[@iwiffitthitotonacc4673]

Gotta mention that the autoimmune response only affects less than 0.0003% of those who get vaccinated.

[@bryanchavez7164]

My thoughts exactly. Read papers that they haven’t really worked out how to make it more cell specific yet.

[@pjdilans1]

Yeah... these sticky spike proteins viruses use to attach to all other body cells wont possibly get stuck to the cells resulting in those body cells being identified as an invader.... sarcasm... Its hard to understand or believe scientists didnt think of that or know that.

[@reneecowan3194]

Great explanation and easy to understand. Everyone should watch this.

[@flavioernst902]

So how do you know you only extracted the spike DNA? I mean we don't fully understand DNA code jet. There is a possibility the cell produces something else which could possibly be very bad.