How to calculate allele frequency?

[@JustGumpy]

Thanks so much! Wasn’t grasping how my professor was teaching but this helped me understand

[@ericablackstock3121]

Hours before my midterm and this explanation saved me! Thank you

[@GeneticsLessons]

How allele frequencies will change if genotype frequencies change: kzbin.info/www/bejne/nHKahqdsgMubgpY How to Find Allele Frequency? kzbin.info/www/bejne/gYi2ip2ci7KAq6c How to Find Allele Frequency kzbin.info/www/bejne/q57TZoada6yDj6M How to find allelic frequencies in a population kzbin.info/www/bejne/q57TZoada6yDj6M

[@lunaestrella3297]

thank you so much, your explanation actually made sense to me!

[@GeneticsLessons]

You are welcome! Thanks for watching.

[@rehanaakram1013]

sir how to calculate allelic frequencies in case of multiple alleles of an autosomal gene,sex linked genes and polyploidy???

[@GeneticsLessons]

Say 3 alleles, OK? F= (a+b+c)^2=1 4 alleles F=(a+b+c+d)^2=1

[@RaviProf]

Dear Sir, thanks for video. What would be the concentration of protein or transcription factors for the minor allele, it has fewer proteins or less transcriptions

[@GeneticsLessons]

Transcriptome (and protein composition - proteome) of the cell depends on two main factors: 1. Time of the cell cycle (some of the genes can up-regulated and down-regulated depending on the cell needs). 2. Cell line (in some organs some genes can be active in others can be completely inactive)

[@RaviProf]

Thank you Sir reply and clearing my doubt. Is it possible that Functional SNP/Nonsynonymous SNP affecting the splicing of gene/change in amino acid

[@GeneticsLessons]

Sure, there are many genetic disorders that are caused by single nucleotide mutation, sometimes even not in gene itself but in regulatory region outside the gene - so even single mutation can substantially change splicing.

[@RaviProf]

Thanks once again Sir,I am glad that you spare your precious time to answer my query. Sir, would you send me your email id.

[@RaviProf]

An SNP G/A was found in the coding region of the examined gene. the resulting codons are ATG and ATA, which both code for tyrosine. The resulting change is, therefore: synonymous, nonsynonymous, shifting of reading frame, stop codon. I believe its nonsynonymous need your suggestions Sir

[@calygirl2706]

You are my life saver! Thank you so much for this video 😉

[@GeneticsLessons]

You are welcome! Thanks for watching.

[@GRYFFETH-gd8qx]

What if they gave you the allele frequency of the recessive single allele? How would I be able to tell the frequency of the dominant phenotype?

[@GeneticsLessons]

Are you serious? if you know the frequency of recessive allele you instantly know the frequency of the dominant allele, just subtract known frequency from 1.

[@Learn-inspire]

Sir, What is the allele frequency of A,B and O blood type in a population having various frequency of A=84 ,B=109 ,AB=47 and O =71 Sir please do it................

[@GeneticsLessons]

You have to use trinomial expansion to solve this problem: (A+B+O)^2 in this formula A, B and O stands for 3 alleles and ^2 stands for diploid number of alleles.

[@Learn-inspire]

Nikolay's Genetics Lessons " Can solve it on page, and do whatsapp [phone]

[@anshulbharti2214]

Avaj to samajh me nahi aya but concept is good 🙏🏻 thanks from ❤️india ❤️

[@ankushkaundal7465]

Awsm trick sir

[@GeneticsLessons]

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[@Spogeboii]

You are the shit. Dont let nobody tell you any different. Thanks so much

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[@1epicdiana]

this helped me so much. Thank you!

[@GeneticsLessons]

Glad it helped!

[@telugufunnymoji5564]

God of genetics

[@ljfresh8170]

how did you get 60% and 40 %

[@GeneticsLessons]

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[@gulzarhossain2699]

Thanks sir, plz many sum video in genetics

[@bende8638]

awsome! very clear to understand

[@GeneticsLessons]

Glad it helped!

[@maharshi3180]

Why we are adding 240 to both of them

[@diwataa]

because you’re splitting the “Aa” in the middle. 480/2 is 240 each for dominant and recessive allele. Hope that helps! Didn’t understand till i rewatched the video 3 times 😅

[@GeneticsLessons]

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[@chummychutoy]

Thx for the help in my homework!

[@elmatabassum4425]

how did you get 60% ?

[@ritrexzz9294]

360 + 240 = 600. (A) 600 divided by (total population) 1000 = .6 or 60%

[@GeneticsLessons]

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[@sanjeevbn1534]

Nice one 🤘🤘

[@komodofpv1267]

THANK YOU SO MUCH

[@GeneticsLessons]

Glad it helped

[@simransingh9306]

thanku so much sir

[@GeneticsLessons]

You're welcome! Thanks for watching.

[@teob1176]

God bless you

[@Masyasmulat1221]

Thank you

[@GeneticsLessons]

You're welcome

[@priyankadube1888]

Thank you so much sir

[@GeneticsLessons]

You are welcome! Thanks for watching.

[@rehanaakram1013]

thank you sir...

[@darkiller89]

Thx and subbed

[@GeneticsLessons]

Welcome!

[@akhilaunni1297]

Thank u sir

[@GeneticsLessons]

Welcome

[@Rockyroad321]

My brain not smart enough to understand biology

[@GeneticsLessons]

It is important to remember that intelligence is not fixed and can be improved with dedication and practice. Anyone can learn biology or any other subject if they have the desire and commitment to do so. It is also essential to recognize that different individuals have different learning styles, and some may find it easier to learn biology than others. Moreover, it is important to have a growth mindset when approaching learning, which means believing that your abilities can be developed through dedication and hard work. Instead of saying "My brain not smart enough to understand biology," it would be more beneficial to say "I need to work hard and consistently to understand biology better."

[@nmesomaeze9699]

Please solve for genotype frequency

[@GeneticsLessons]

I have hundreds of such problems - just check my channel for play list "genotype and phenotype frequencies"

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[@praptimondal5871]

Yes

[@GeneticsLessons]

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[@mslovelee86]

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[@Mysteriousloverhere]

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[@vbabilani]

Why we are adding 240 to both of them

[@GeneticsLessons]

Because Aa conist of "A" and "a" alleles1/2 A and 1/2 a.