How to calculate protein-protein interactions in PyMol?

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Bioinformatics Insights

Bioinformatics Insights

Күн бұрын

Download Link for the script: pymolwiki.org/index.php/Inter...
Welcome to Bioinformatics Insights. This video tutorial will teach you the analysis and calculation of identifying Protein-Protein Interface in a complex PDB structure.
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Пікірлер: 4
@zeeshankhan-mo3sd
@zeeshankhan-mo3sd 4 ай бұрын
You have done great job
@Bioinformaticsinsights
@Bioinformaticsinsights 4 ай бұрын
Thanks for taking interest. Please share it in your community, it might help some one else too.
@juliangrandvallet5359
@juliangrandvallet5359 Ай бұрын
This is extremely helpful, Dr. Quick question, what happens if I already know the interaction sited between the 2 proteins? Can I give that to the script? Because I want to compare the interaction between 2 different proteins (2 different PDB codes)
@Bioinformaticsinsights
@Bioinformaticsinsights Ай бұрын
@Julia if you the interaction interface exactly, then I suggest you to show those residues in PyMol. Why you want to tell the script the these two residues, the script is supposed to identify those two already. In case not then look to he script and tweak the cutoff distance, save and rerun. Yes you can identify between two different proteins, if they are in a complex. If they are individual proteins from PDB, in that case you have to dock them first.
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