How to iterate or loop over all the pandas dataframe columns names and rename them or modify them

Python pandas tutorial for beginners on how to loop over all the pandas dataframe column name and changing their name to lowercase or uppercase or replacing space with underscore etc. to make them consistent for data analysis.
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[@prashanthardikar9895]

Does it take a regular expression in replace()

[@arshad1781]

Thanks

[@mohammedchaoukyousrhir1357]

Thank s for this video, please I'm a beginner in Pandas, i want to rename columns that are variants : 0 1 2 3 4 5 Name X 527 547 24 66 70.0 Y 537 552 26 45 57.0 Z 534 540 40 50 68.0 for 1 and 2 ... 5 i want rename those columns , knowing that columns are variants. Thank's a lot.