How to solve aging | David Sinclair and Lex Fridman

Lex Fridman Podcast full episode: • David Sinclair: Extend...
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GUEST BIO:
David Sinclair is a geneticist at Harvard and author of Lifespan.
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[@ramicaza]

No one's going to talk about how this dude's friend cloned his dog 3 times...

[@kubalewandowski8913]

hey did his friend just cloned his dog 3 times?

[@davidlakhter]

LOL I was thinking the same thing

[@terria.2581]

@@Derty_the_grower they can ban you from a KZbin channel? I never knew this. I knew you could have your own channel and content banned but never knew they could actually ban you from watching a specific channel? That's crazy if it's true..

[@alicantuncer4800]

@@terria.2581 yeah, u can block other profiles to post on your uploads

[@johnphil2006]

Lex, you are bringing the universe to a new paradigm shift by introducing these genius ! Hats off you. 👏

[@guy6567]

thanks lex

[@jb7707]

It fascinates me that some of our oldest stories and best literature warns against seeking "immortality" and the perils of wanting to live forever, yet we still value a long life and seek longer lifespans.

[@hynjus001]

The fight against aging is our modern day tower of babel.

[@stephenbell8337]

Love your work Lex. Hit the spot that one did.

[@NASJAQ]

i'd love to have david on my podcast. brilliant guy

[@davidlakhter]

so it's not necessarily about the shortening of the telomers, but the scratches of the genome that prevents proper expression in a given cell

[@nedi1150]

Hey Lex...can you get his friend on...the guy that just casually clones his dog, please, and thanks.

[@mstr293]

Calorie restriction, OMAD and resveratrol only prolongs our lifespans but doesn't reverse it: That's step 1. Reversing aging is currently unknown but the likes of Sinclair, De Grey and other gerontologist are looking for ways to reverse it and some of them successfully did it on mice: Step two is keep in touch and updated with these people's research AND HOPE that stage 1 would help you live long enough once human trials becomes a reality. Stage three is just my theory. This currently falls within the realm of sci-fi so take it with a grain of salt: I believe that the next stage would be human resurrection. My own take on it since 2004 is a machine that works like a human womb but instead of fetuses, it would be used for bodies that have been recently deceased. Those who put themselves/their dead bodies in cryogenic chambers hope that this type of technology would come true. Hopefully, the success of stage 2 would give us more time for this.

[@yanbibiya]

I dismissed it as you recommended

[@HigherPlanes]

There are lots of stories of whales in the arctic north that still have harpoons lodged in their bodies from the 1800's. Cold temperatures slow ageing. There are microbes that literally live for thousands of years in the freezing cold away from any sunlight.

[@YSFmemories]

i dont think you'd live for very long in the fridge

[@HigherPlanes]

@@YSFmemories Yeah I don't think that's how it works.

[@Khodam101]

In the back of my mind, Singing who wants to live forever! 🎹🎶🎼🎵

[@hermangill8989]

Lex laughs at the randomest things - “you studied bread!” 😂

[@filipinoblackpill6194]

to reverse aging is to seek for enlightenment, not only you are much conscious with the food you take your at peace which lessen the stress of the mind and body.

[@Joseph93]

Can we control our epigenome through conscious choices to the extent we can change how we read our genome?

[@Joseph93]

It makes me wonder if evolution is to some extent “consciously guided” by will in addition to environment

[@Sethslater]

“You studied bread” lol

[@passionnote3922]

That was too funny

[@stockoholics5821]

Finally, a podcast host who let's his guest talk without interrupting or the need to hear himself talk

[@hynjus001]

Finally, a guest who says "One of my friends cloned his dog 3 times"

[@filipinoblackpill6194]

aging also is how you track down your food consumption from 20s upto old age, you cant just cut sugar or processed food when your on your 50s, toolate the damage is already taken place.

[@AR-mx5tc]

"you can clone dog.. One of my friends cloned a dog...3 times..." wtf??? why we not doin this everywhere?!

[@primedailyquotes8759]

Because people are poor lol

[@cryptohouse1676]

The next google or tesla stock is probably going to be in this anti-aging space. Imagine if they get a breakthrough that actually works. People would be willing to give all their money for more youth and time.

[@SpaceTimeBeing_]

Nope. Your aging shouldn't be under their control. It needs to available in hospitals or as free and open source technology.

[@cryptohouse1676]

@@SpaceTimeBeing_ I think reversing aging will never happen in our lifetime if we leave it up to «idealistic» government researchers and hope it will be a free treatment for all. Without giant financial incentives the research will be so slow and involve too few people. I think the government should issue some really large financial awards for companies or individuals that can demonstrate treatments that work. But the thing is, if they actually work, the market will reward them financially anyway. Personally, I am willing to go into crippling debt if it means I can extend my life and reverse the aging process.

[@cryptohouse1676]

@@SpaceTimeBeing_ I mean, solving the problem of aging is extremely hard. It could be like fusion energy. Scientists have been working on fusion for many decades, yet we are still far from having any useful fusion reactors. Most likely aging will not be reversed in our lifetime, but I think it is worth a shot. Worst case, we die as people always have. Best case, we live on! The problem should be tackled from every angle and with all means. Be it governments or greedy private companies. I would rather have a 60% chance of survival and Google owning the cure, than 30% chance of survival but government giving the cure for free.

[@sethbelanger8460]

TRT, GH and metformin? Yup, I think I nailed it.

[@nathanforrest3483]

Don't get married...

[@keenheat3335]

the thing i dont get is why children are capable of be born young if the source parent cell already have these information degraded through aging ? something about the gestation process repair the effect of cellular information degradation ? I guess if neural link is sufficiently advance to download memory onto a fresh brain, you could technically grow a youthful body and just transfer the memory into. Disregarding the whole who's the real clone argument aside.

[@AA-gl1dr]

Human eggs are all made at once at the start of life and released one by one. They’re not made at will continuously like sperm.

[@yammy1688]

TCPip doesn’t work that way 😊

[@WhiteDrake77]

Don't be pedantic, this is what he was referring to: If a packet error occurs, TCP (Transmission Control Protocol) will resend the same information repeatedly, in hopes the data will eventually reach the destination without any problems

[@bengsynthmusic]

So in other words, we age because we rust. Let's go stainless.

[@ahmedoqaidi8088]

We need to find a process or some kind of coating

[@princethomas1566]

I trade features on a better exchange with less fee's. Speaking of FX trading, it's really one of the best business in the world right now, & I make money trading this Financial markets.

[@lucasmiguel5771]

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[@georgewilson2434]

You trade with Christiana? , I'm currently on my 5th trade with her and my Ptfolio has grown big..

[@mariarebecca3080]

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[@Freeforexsignal247ontelegrann]

(Hey im New!, just started with Christiana Monday precisely, she charges a 15% commission on profit made after every trading session and that's fair compared to the effort she puts in to make huge profit

[@tinacruz4430]

I trade with her too. Truth is, a lot of KZbinrs dont actually care if you loose money, they just want more views and traffic! this is why i respect her. She actually takes her time to coach you in steps

[@abdullahnassif6187]

Lex must know about Ripple and the XRPL by now.

[@Gregoaklandmusic]

YOU STUDIED BREAD? - lex fridman

[@MrSkatebox09]

are we already computers??

[@kevinschmidt2171]

Solve aging? I hate that sentence and thought. Aging is a very important perk to humanity. If we get rid of aging or extend life time too much we will stop being a society, we will stop being humanity.

[@enio1111]

Bs

[@MohakJoshi1]

I'm more interested about dog cloning

[@ASMRMoto]

The real question is should aging be solved ? whatever designed this simulation probably knows better in allocating time for every species .. there are plants that live for thousands of years and insects that live for a mere week . waking from a simulation could be blessing in disguise . Solving aging is like solving high school and staying there forever . maybe death is a natural upgrade of consciousness.

[@piersyfy4148]

Lol people joked that the simulation theory thing is just a new religion but you're really taking it there

[@DJC_2003]

There is no simulations there are no gods, nothing was planned it just happened

[@DJC_2003]

You are a product of your brain stop fooling yourself

[@petchlnwzaaa]

Did he just casually said human are pathetic? lol 💀

[@Mr_Anderson_one]

What about kids? Don' t they get a fresh copy of info?

[@VGLV888]

✅☑️

[@AR-mx5tc]

ooh shi actually caught it before 200 views wtf lmfao. so random...

[@abdullahnassif6187]

XRP

[@brianw.4147]

@@johnmcafee2751 matic

[@furkansarihan]

Not that hard

[@reymorales6786]

Who cares about humans aging. Can we figure out how to make our dogs age less quickly first??

[@primedailyquotes8759]

No. Dogs are not that important. They’re just animals.

[@crowkangi]

with a.i. we'll build a god.. but can we turn ourselves into demigods and live indefinitely. if capitalism doesnt kill us all we might have a chance.

[@NASJAQ]

first

[@wherethereslifethereshope9858]

Lex, are you a JW?

[@brjm1604]

David Sinclair sounds like he would hold a great BBQ .... Not!!

[@ProCoach2373]

In the bible God states that our lives will be 120 years. It's held true as the oldest humans have been right around that age. While scientists are valuable on this planet, my faith is in God.

[@DJC_2003]

I guess it's god that does life saving surgeries on people right? I guess it's god that would let them die if they didn't have access to those surgeons right?

[@ProCoach2373]

@@DJC_2003 God gave them the ability and intelligence. It's a matter of perception.

[@ScannyProductions]

the host is totally drunk...

[@frawcisca]

I agree

[@BDS_78]

I disagree with most of what David Sinclair said…

[@graysonmorrow7886]

How so?

[@SpaceTimeBeing_]

Who are you and why?

[@lindegirl3334]

Everyone needs to find out what Trump is on and doing……actually look closely at the super rich they seem to be staying the same and have lots of energy..🇺🇸🇺🇸🇺🇸

[@PaxMundi118]

Trump eats children in the basement of a pizza restaurant.

[@yanbibiya]

You can't boil it down. This chap is just a bit of a quack. It's a hallmark...

[@azhivago2296]

History tells us many "quacks" deliver - one would do well to keep an open mind.

[@yanbibiya]

That's a very cheap reply. One has to access each quack on it'd merits. People want to believe...this kind of belief has existed since the beginning. The hope of it.

[@azhivago2296]

Sorry you feel that way.

[@yanbibiya]

@@azhivago2296 that's very helpful

[@azhivago2296]

Ah